Scholars@Duke
Angel V Peterchev

Angel V Peterchev

Professor in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
40 Duke Medicine Circle, Box 3620 DUMC, Durham, NC 27710

Scholarly Works - Preprints

Acute Increase of Excitatory Activity in Pyramidal Neurons of Rat Motor Cortex under Static Magnetic Field

Preprint · July 22, 2026 Objectives: Transcranial application of a static magnetic field (SMF) was reported to result in subsequent modulation of neural excitability in the human motor cortex, but the acute mechanisms underlying this effect are unknown. We explore the mech ... Full text Cite

Histologically Informed Multiscale Modeling of the Neuronal Elements Activated by TMS.

Preprint · June 9, 2026 BACKGROUND: The primary neural site(s) at which action potentials are initiated by transcranial magnetic stimulation (TMS) remain poorly understood. Multiscale computational models provide biophysically based hypotheses, but model accuracy is constrained b ... Full text Link to item Cite

Understanding the mechanisms of lateral parietal memory modulation in Mild Cognitive Impairment

Preprint · 2026 The application of transcranial magnetic stimulation (TMS) to lateral parietal cortex has shown promise in improving episodic memory in older adults with Mild Cognitive Impairment (MCI). Previous work has suggested that such improvements are achieved by ac ... Full text Cite

Kilohertz transcranial magnetic perturbation (kTMP) as a new non-invasive method to modulate cortical excitability.

Preprint · September 3, 2025 Non-invasive brain stimulation (NIBS) provides a method for safely perturbing brain activity, and has been employed in basic research to test hypotheses concerning brain-behavior relationships with increasing translational applications. We introduce and ev ... Full text Link to item Cite

Motor network reorganization associated with rTMS-induced writing improvement in writer's cramp dystonia.

Preprint · January 18, 2025 BACKGROUND: Writer's cramp (WC) dystonia is an involuntary movement disorder with distributed abnormalities in the brain's motor network. Prior studies established the potential for repetitive transcranial magnetic stimulation (rTMS) to either premotor cor ... Full text Link to item Cite

Reduced Auditory Perception and Brain Response with Quiet TMS Coil.

Preprint · July 2, 2024 BACKGROUND: Electromagnetic forces in transcranial magnetic stimulation (TMS) coils generate a loud clicking sound that produces confounding auditory activation and is potentially hazardous to hearing. To reduce this noise while maintaining stimulation eff ... Full text Link to item Cite

Kilohertz Transcranial Magnetic Perturbation (kTMP): A New Non-invasive Method to Modulate Cortical Excitability

Preprint · March 18, 2024 AbstractBackgroundNon-invasive brain stimulation (NIBS) provides a method for safely perturbing brain activity, and has been employed in basic research to test hypotheses concernin ... Full text Cite

Circuits and Mechanisms for TMS-Induced Corticospinal Waves: Connecting Sensitivity Analysis to the Network Graph

Preprint · 2024 ABSTRACT Transcranial magnetic stimulation (TMS) is a non-invasive, FDA-cleared treatment for neuropsychiatric disorders with broad potential for new applications, but the neural circuits that are engaged during TMS are still poorly understood. R ... Full text Cite

Three Novel Methods for Determining Motor Threshold with Transcranial Magnetic Stimulation Outperform Conventional Procedures

Preprint · 2022 Objective Thresholding of neural responses is central to many applications of transcranial magnetic stimulation (TMS), but the stochastic aspect of neuronal activity and motor evoked potentials (MEPs) challenges thresholding methods. We analyzed ... Full text Cite