Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellowship, Rheumatology, Duke University School of Medicine 2008 - 2010
  • Resident, Internal Medicine, Duke University School of Medicine 2005 - 2008
  • M.D., University of Medicine and Dentistry of New Jersey 2005
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Medicine, Medicine, Rheumatology and Immunology, Medicine 2012 - 2021
• Research
• 

  Selected Grants

  • A randomized, double-blind, placebo-controlled, repeat-dose, multicenter trial to evaluate the efficacy, safety, tolerability and pharmscokinetics of HZN-825 in patients with Diffuse Cutaneous Systemic Sclerosis awarded by Horizon Therapeutics Ireland DAC 2022 - 2024
  • ACE Covid 19 Admin. Supplement: Molecular Regulation of B cells and T cells in Human SLE - Cost Reimbursable awarded by Emory University 2021 - 2023
  • Collaborative National Quality and Efficacy Registry for Tracking Disease Progression in Systemic Sclerosis Scleroderma) Patients awarded by Scleroderma Research Foundation 2022 - 2023
  • Evaluation of Brentuximab Vedotin for Diffuse Cutaneous Systemic Sclerosis: A Phase I/II Multicenter, Randomized, Double-Blinded Safety Study - Cost Reimbursable Code awarded by Benaroya Research Institute at Virginia Mason 2021 - 2023
  • Evaluation of Brentuximab Vedotin for Diffuse Cutaneous Systemic Sclerosis: A Phase I/II Multicenter, Randomized, Double-Blinded Safety Study - Fixed Price Code awarded by Benaroya Research Institute at Virginia Mason 2018 - 2023
  • A trial to evaluate the safety of long term treatment with nintedanib in patients with scleroderma related lung fibrosis. awarded by Boehringer Ingelheim Pharmaceuticals, Inc. 2018 - 2021
  • Symptom Clusters in Systemic Sclerosis awarded by National Institutes of Health 2020 - 2021
  • An Extended Access Program to Assess Long-Term Safety of Bardoxolone Methyl in Patients with Pulmonary Hypertension awarded by Reata Pharmaceuticals, Inc. 2017 - 2021
  • Reata CTD with PAH awarded by Reata Pharmaceuticals, Inc. 2016 - 2021
  • Affinergy Scleroderma Antibody study awarded by Affinergy, LLC 2018 - 2020
  • Validation of an Algorithm to Identify Incident Interstitial Lung Disease in Patients with Rheumatoid Arthritis awarded by University of Alabama at Birmingham 2018 - 2020
  • A double blind, randomised, placebo-controlled trial evaluating efficacy and safety of oral nintedanib treatment for at least 52 weeks in patients with `Systemic Sclerosis associated Interstitial Lung Disease'(SSc-ILD). awarded by Boehringer Ingelheim Pharmaceuticals, Inc. 2016 - 2019
  • STAR Scleroderma awarded by Cytori Therapeutics, Inc. 2015 - 2018
• 

  External Relationships

  • Affinergy, Inc.
  • Boehringer Ingleheim
  • Grand Rounds
  • Horizon Pharmaceuticals
  • Reata
  • Seattle Genetics
  • Talaris
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Shah, Ankoor, Jan Storek, Rob Woolson, Ashley Pinckney, Lynnette Keyes-Elstein, Paul K. Wallace, Gregory D. Sempowski, et al. “Lymphocyte subset abnormalities in early severe scleroderma favor a Th2 phenotype and are not altered by prior immunosuppressive therapy.” Rheumatology (Oxford) 61, no. 10 (October 6, 2022): 4155–62. https://doi.org/10.1093/rheumatology/keac015.
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    • Khanna, Dinesh, Paul Caldron, Richard W. Martin, Suzanne Kafaja, Robert Spiera, Shadi Shahouri, Ankoor Shah, et al. “Adipose-Derived Regenerative Cell Transplantation for the Treatment of Hand Dysfunction in Systemic Sclerosis: A Randomized Clinical Trial.” Arthritis Rheumatol 74, no. 8 (August 2022): 1399–1408. https://doi.org/10.1002/art.42133.
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    • Maheswaranathan, Mithu, Anand S. Lagoo, Louis Diehl, and Ankoor Shah. “A 79-Year-Old Female Patient With Altered Mental Status and Anemia.” Arthritis Care Res (Hoboken) 74, no. 4 (April 2022): 555–61. https://doi.org/10.1002/acr.24571.
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    • Maheswaranathan, Mithu, Anne F. Buckley, Andrew B. Cutler, Lisa Criscione-Schreiber, and Ankoor Shah. “Cerebral Autosomal-Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Syndrome, a Central Nervous System Vasculitis Mimic.” Arthritis Rheumatol 73, no. 12 (December 2021): 2239. https://doi.org/10.1002/art.41922.
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    • Shah, Ankoor, J. Spierings, J. M. van Laar, and Keith M. Sullivan. “Re-evaluating inclusion criteria for autologous hematopoietic stem cell transplantation in advanced systemic sclerosis: Three successful cases and review of the literature.” J Scleroderma Relat Disord 6, no. 2 (June 2021): 199–205. https://doi.org/10.1177/2397198320985766.
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    • Cardones, Adela R., Russell P. Hall, Keith M. Sullivan, Joanna Hooten, Seung Yun Lee, Beiyu Liu, Cynthia L. Green, et al. “Quantifying Skin Stiffness in Graft-Versus-Host Disease, Morphea, and Systemic Sclerosis Using Acoustic Radiation Force Impulse Imaging and Shear Wave Elastography.” J Invest Dermatol 141, no. 4 (April 2021): 924-927.e2. https://doi.org/10.1016/j.jid.2020.07.031.
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    • Ramalingam, Sendhilnathan, and Ankoor Shah. “Stem Cell Therapy as a Treatment for Autoimmune Disease-Updates in Lupus, Scleroderma, and Multiple Sclerosis.” Curr Allergy Asthma Rep 21, no. 3 (March 24, 2021): 22. https://doi.org/10.1007/s11882-021-00996-y.
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    • Marano, A. L., J. M. Clarke, M. A. Morse, A. Shah, W. Barrow, M. A. Selim, R. P. Hall, and A. R. Cardones. “Subacute cutaneous lupus erythematosus and dermatomyositis associated with anti-programmed cell death 1 therapy.” Br J Dermatol 181, no. 3 (September 2019): 580–83. https://doi.org/10.1111/bjd.17245.
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    • Butler, Emily-Ann, Murray Baron, Agnes B. Fogo, Tracy Frech, Cybele Ghossein, Eric Hachulla, Sabrina Hoa, et al. “Generation of a Core Set of Items to Develop Classification Criteria for Scleroderma Renal Crisis Using Consensus Methodology.” Arthritis Rheumatol 71, no. 6 (June 2019): 964–71. https://doi.org/10.1002/art.40809.
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    • Pauling, John D., Tracy M. Frech, Michael Hughes, Jessica K. Gordon, Robyn T. Domsic, Marina E. Anderson, Francesca Ingegnoli, et al. “Patient-reported outcome instruments for assessing Raynaud's phenomenon in systemic sclerosis: A SCTC Vascular Working Group Report.” J Scleroderma Relat Disord 3, no. 3 (October 2018): 249–52. https://doi.org/10.1177/2397198318774307.
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    • Leverenz, David L., Christopher Henderson, and Ankoor Shah. “Atypical Cutaneous Presentations of Sarcoidosis: Two Case Reports and Review of the Literature.” Curr Allergy Asthma Rep 18, no. 8 (June 14, 2018): 40. https://doi.org/10.1007/s11882-018-0794-6.
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    • Rolls, S., S. Rajan, A. Shah, J. F. Bourke, M. M. Chowdhury, S. A. Ghaffar, C. Green, et al. “(Meth)acrylate allergy: frequently missed?” Br J Dermatol 178, no. 4 (April 2018): 980–81. https://doi.org/10.1111/bjd.16402.
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    • Guerriero, Réjean M., Archana A. Patel, Brian Walsh, Fiona M. Baumer, Ankoor S. Shah, Jurriaan M. Peters, Lance H. Rodan, Pankaj B. Agrawal, Phillip L. Pearl, and Masanori Takeoka. “Systemic Manifestations in Pyridox(am)ine 5'-Phosphate Oxidase Deficiency.” Pediatr Neurol 76 (November 2017): 47–53. https://doi.org/10.1016/j.pediatrneurol.2017.05.024.
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    • Balevic, Stephen J., and Ankoor Shah. “Islands of Inflammation: Neurosarcoidosis.” Am J Med 130, no. 2 (February 2017): 157–60. https://doi.org/10.1016/j.amjmed.2016.09.009.
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    • Sullivan, Keith M., Ankoor Shah, Stefanie Sarantopoulos, and Daniel E. Furst. “Review: Hematopoietic Stem Cell Transplantation for Scleroderma: Effective Immunomodulatory Therapy for Patients With Pulmonary Involvement.” Arthritis Rheumatol 68, no. 10 (October 2016): 2361–71. https://doi.org/10.1002/art.39748.
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    • Smith, Lewis J., Ravi Kalhan, Robert A. Wise, Elizabeth A. Sugar, John J. Lima, Charles G. Irvin, Allen J. Dozor, Janet T. Holbrook, and Janet T. American Lung Association Asthma Clinical Research Centers. “Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: a randomized clinical trial.” Jama 313, no. 20 (May 26, 2015): 2033–43. https://doi.org/10.1001/jama.2015.5024.
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    • Ansher, Cara, Dan Ariely, Alisa Nagler, Mariah Rudd, Janet Schwartz, and Ankoor Shah. “Better medicine by default.” Med Decis Making 34, no. 2 (February 2014): 147–58. https://doi.org/10.1177/0272989X13507339.
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    • Henderson, Carl S., Andrew C. Madison, and Ankoor Shah. “Size matters--nanotechnology and therapeutics in rheumatology and immunology.” Curr Rheumatol Rev 10, no. 1 (2014): 11–21. https://doi.org/10.2174/1573403x10666140914155926.
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    • Shah, Ankoor. “The pathologic and clinical intersection of atopic and autoimmune disease.” Curr Allergy Asthma Rep 12, no. 6 (December 2012): 520–29. https://doi.org/10.1007/s11882-012-0293-0.
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    • Shah, Ankoor, and Robert T. Keenan. “Gout, hyperuricemia, and the risk of cardiovascular disease: cause and effect?” Curr Rheumatol Rep 12, no. 2 (April 2010): 118–24. https://doi.org/10.1007/s11926-010-0084-3.
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    • Andersen, Nicholas D., John Dubose, Ankoor Shah, Teng Lee, Stephanie B. Wechsler, and G Chad Hughes. “Thoracic endografting in a patient with hereditary hemorrhagic telangiectasia presenting with a descending thoracic aneurysm.” J Vasc Surg 51, no. 2 (February 2010): 468–70. https://doi.org/10.1016/j.jvs.2009.08.058.
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    • Shah, Ankoor, Louis F. Diehl, and E William St Clair. “T cell large granular lymphocyte leukemia associated with rheumatoid arthritis and neutropenia.” Clin Immunol 132, no. 2 (August 2009): 145–52. https://doi.org/10.1016/j.clim.2009.03.515.
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  • Conference Papers

    • Shah, Ankoor, Megan Clowse, Daniel Wojdyla, and Amanda Eudy. “Primary Non-adherence in Patients with Systemic Lupus Erythematosus.” In Arthritis & Rheumatology, Vol. 72, 2020.
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    • Shah, Ankoor, Jan Storek, Rob Woolson, Lynette Keyes-Elstein, Paul Wallace, Maureen D. Mayes, Leslie Crofford, et al. “Lymphocyte Immunophenotypes at Randomization on the Scleroderma: Cyclophosphamide or Transplantation Trial: Comparison of Treatment Naive and DMARD Treated Participants with Healthy Controls.” In Arthritis & Rheumatology, Vol. 70. WILEY, 2018.
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    • Xie, Fenglong, Narender Annapureddy, Lang Chen, Jason Leonard Lobo, Jim C. Oates, Ankoor Shah, Huifeng Yun, Shuo Yang, and Jeffrey R. Curtis. “Rheumatoid Arthritis and the Risk for Interstitial Lung Disease: A Comparison of Risk Associated with Biologic and Conventional Dmards.” In Arthritis & Rheumatology, Vol. 69. WILEY, 2017.
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    • Khanna, Dinesh, Maureen D. Mayes, Robert W. Simms, Virginia D. Steen, Steven Cohen, Paul Caldron, Richard Martin, et al. “Feasibility of Same Day Adipose Tissue Harvest, Cell Processing and Subcutaneous Delivery of Adipose Derived Regenerative Cells into Fingers of Scleroderma Patients within a Randomized Double Blind Clinical Trial.” In Arthritis & Rheumatology, Vol. 68. WILEY, 2016.
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    • Pauling, John, Tracy M. Frech, Michael Hughes, Jessica K. Gordon, Robyn T. Domsic, Francesca Ingegnoli, Neil J. McHugh, et al. “Attitudes Toward Patient-Reported Outcome Instruments for the Assessment of Raynaud's Phenomenon in Systemic Sclerosis.” In Arthritis & Rheumatology, Vol. 68. WILEY, 2016.
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    • Chao, Nelson J., Yevgeniya Gora Foster, Krista Rowe, Ankoor Shah, and Adela Rambi Cardones. “Pulse Cyclophosphamide for Steroid-Refractory Chronic Graft-Versus-Host Disease.” In Biology of Blood and Marrow Transplantation, 22:S393–95. Elsevier BV, 2016. https://doi.org/10.1016/j.bbmt.2015.11.918.
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    • Shah, Ankoor, Samuel Broderick, Karen Chiswell, Asba Tasneem, and John S. Sundy. “Status of the Allergy and Immunology Clinical Trials Portfolio: Data From Clinicaltrials.Gov.” In Journal of Allergy and Clinical Immunology, 131:AB107–AB107. Elsevier BV, 2013. https://doi.org/10.1016/j.jaci.2012.12.1055.
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    • Shah, Ankoor, Samuel Broderick, Karen Chiswell, Asba Tasneem, and John S. Sundy. “Status of the Rheumatology Clinical Trials Portfolio: Data From Clinicaltrials.Gov.” In Arthritis and Rheumatism, 64:S785–86. WILEY-BLACKWELL, 2012.
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    • Shah, Ankoor, and John S. Sundy. “Predictors of Outcomes in Gout with Comorbid Chronic Kidney Disease.” In Arthritis and Rheumatism, 63:S404–S404. WILEY-BLACKWELL, 2011.
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