Scholars@Duke
Ankoor Shah

Ankoor Shah

Associate Professor of Medicine
Medicine, Rheumatology and Immunology
ankoor.shah@duke.edu
Box 3874, Durham, NC 27710
Duke South, Purple Zone, Room, Durham, NC 27710

Scholarly Works - Journal articles

Palliative Care in Rheumatology: Perspectives of Rheumatologists and Palliative Care Clinicians Across the United States.

Journal article J Rheumatol · August 1, 2026 OBJECTIVE: To explore perspectives of rheumatologists and palliative care (PC) clinicians on the role of PC in rheumatic disease (RD). METHODS: We developed 2 questionnaires, 1 for rheumatologists and a second for PC clinicians, exploring education about t ... Full text Link to item Cite

Association of Type III and Type VI Collagen Neoepitopes With Disease Severity in Systemic Sclerosis.

Journal article J Rheumatol · May 1, 2026 OBJECTIVE: Dysregulated collagen turnover is implicated in systemic sclerosis (SSc) pathogenesis. We evaluated collagen turnover biomarkers in relation to the severity of fibrotic manifestations, key cytokines, and progression in SSc. METHODS: Baseline and ... Full text Link to item Cite

Paging Palliative Care: Barriers to Referral and Why Rheumatologists Aren't Making the Call (Yet).

Journal article J Pain Symptom Manage · December 2025 PAGING PALLIATIVE CARE: Barriers to Referral and Why Rheumatologists Aren't Making the Call (Yet). CONTEXT: People with serious rheumatic disease experience high morbidity and mortality, yet palliative care (PC) remains an underutilized resource for these ... Full text Link to item Cite

Hand Swelling and Other Non-Raynaud Phenomenon Symptoms as the Initial Presentation of Systemic Sclerosis: Prevalence and Clinical Associations in Two US Cohorts.

Journal article Arthritis Rheumatol · November 2025 OBJECTIVE: Raynaud phenomenon (RP) is often the initial clinical manifestation of systemic sclerosis (SSc), but some patients develop other manifestations first. To help elucidate the diversity of SSc presentation in its early stages, we describe the initi ... Full text Link to item Cite

Psychometric Evaluation of the Scleroderma Skin Questionnaire: A Novel Patient-Reported Outcome for Skin Disease in Patients With Systemic Sclerosis.

Journal article J Rheumatol · March 1, 2025 OBJECTIVE: We aimed to evaluate the psychometric properties of the Scleroderma Skin Questionnaire (SSQ), a novel patient-reported outcome (PRO) to assess systemic sclerosis (SSc)-related skin symptoms. METHODS: Participants were recruited from the SSc Coll ... Full text Link to item Cite

Using linked electronic medical record-pharmacy data to examine lupus medication adherence: A retrospective cohort study.

Journal article Lupus · October 2024 INTRODUCTION: Medication nonadherence is common in systemic lupus erythematosus (SLE) and associated with morbidity and mortality. We explored the reliability of pharmacy data within the electronic medical record (EMR) to examine factors associated with no ... Full text Link to item Cite

Pregnancy Outcomes of Women Veterans with Autoimmune Disease.

Journal article Womens Health Rep (New Rochelle) · 2024 BACKGROUND/OBJECTIVE: Women Veterans (WV) are exposed to unique risk factors for the development of autoimmune diseases (AID), which can increase risk of pregnancy complications. To characterize pregnancy outcomes in this population, our team performed a d ... Full text Link to item Cite

CONQUER Scleroderma: association of gastrointestinal tract symptoms in early disease with resource utilization.

Journal article Rheumatology (Oxford) · October 3, 2023 OBJECTIVES: SSc is associated with increased health-care resource utilization and economic burden. The Collaborative National Quality and Efficacy Registry (CONQUER) is a US-based collaborative that collects longitudinal follow-up data on SSc patients with ... Full text Link to item Cite

Lymphocyte subset abnormalities in early severe scleroderma favor a Th2 phenotype and are not altered by prior immunosuppressive therapy.

Journal article Rheumatology (Oxford) · October 6, 2022 OBJECTIVES: The Scleroderma: Cyclophosphamide or Transplantation (SCOT) trial compared hematopoietic stem cell transplant to CYC treatment in patients with early SSc with progressive skin and lung or kidney involvement. Here we describe lymphocyte phenotyp ... Full text Link to item Cite

Adipose-Derived Regenerative Cell Transplantation for the Treatment of Hand Dysfunction in Systemic Sclerosis: A Randomized Clinical Trial.

Journal article Arthritis Rheumatol · August 2022 OBJECTIVE: Hand dysfunction is common in systemic sclerosis (SSc). We undertook this study to evaluate the capacity of autologous adipose-derived regenerative cells (ADRCs) to improve hand function in SSc patients. METHODS: The Scleroderma Treatment with C ... Full text Link to item Cite

A 79-Year-Old Female Patient With Altered Mental Status and Anemia.

Journal article Arthritis Care Res (Hoboken) · April 2022 Full text Link to item Cite

Re-evaluating inclusion criteria for autologous hematopoietic stem cell transplantation in advanced systemic sclerosis: Three successful cases and review of the literature.

Journal article J Scleroderma Relat Disord · June 2021 Systemic sclerosis is a chronic autoimmune disease with a poor prognosis, particularly when a patient has rapidly progressive skin or pulmonary involvement. Autologous hematopoietic stem cell transplant is an emerging treatment for this condition, that has ... Full text Link to item Cite

Stem Cell Therapy as a Treatment for Autoimmune Disease-Updates in Lupus, Scleroderma, and Multiple Sclerosis.

Journal article Curr Allergy Asthma Rep · March 24, 2021 PURPOSE OF REVIEW: Evidence for hematopoietic stem cell transplantation (HCT) in autoimmune disease has been building since the 1990s; however, many clinicians may not yet be aware of its applications to autoimmune disease. We review the basic tenets of HC ... Full text Link to item Cite

Subacute cutaneous lupus erythematosus and dermatomyositis associated with anti-programmed cell death 1 therapy.

Journal article Br J Dermatol · September 2019 Programmed cell death 1 (PD-1) blockade has rapidly emerged as an effective therapy for a wide variety of metastatic malignancies. It has been associated with multiple immune-related adverse effects, including cutaneous eruptions. We describe two patients ... Full text Link to item Cite

Generation of a Core Set of Items to Develop Classification Criteria for Scleroderma Renal Crisis Using Consensus Methodology.

Journal article Arthritis Rheumatol · June 2019 OBJECTIVE: To generate a core set of items to develop classification criteria for scleroderma renal crisis (SRC) using consensus methodology. METHODS: An international, multidisciplinary panel of experts was invited to participate in a 3-round Delphi exerc ... Full text Link to item Cite

Patient-reported outcome instruments for assessing Raynaud's phenomenon in systemic sclerosis: A SCTC Vascular Working Group Report.

Journal article J Scleroderma Relat Disord · October 2018 The episodic nature of Raynaud's phenomenon (RP) in systemic sclerosis (SSc) has led to a reliance on patient-reported outcome (PRO) instruments such as the Raynaud's Condition Score (RCS) diary. Little is known about the utilisation in routine clinical pr ... Full text Link to item Cite

Atypical Cutaneous Presentations of Sarcoidosis: Two Case Reports and Review of the Literature.

Journal article Curr Allergy Asthma Rep · June 14, 2018 PURPOSE OF REVIEW: The goal of this review is to provide the reader with an updated summary of the cutaneous manifestations of systemic sarcoidosis, with a particular emphasis on the predilection of sarcoidosis for scars, tattoos, and other areas of trauma ... Full text Link to item Cite

(Meth)acrylate allergy: frequently missed?

Journal article Br J Dermatol · April 2018 Full text Link to item Cite

Systemic Manifestations in Pyridox(am)ine 5'-Phosphate Oxidase Deficiency.

Journal article Pediatr Neurol · November 2017 OBJECTIVE: Pyridoxine is converted to its biologically active form pyridoxal-5-phosphate (P5P) by the enzyme pyridox(am)ine 5'-phosphate oxidase and serves as a cofactor in nearly 200 reactions in the central nervous system. Pyridox(am)ine 5'-phosphate oxi ... Full text Link to item Cite

Islands of Inflammation: Neurosarcoidosis.

Journal article Am J Med · February 2017 Full text Link to item Cite

Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: a randomized clinical trial.

Journal article JAMA · May 26, 2015 IMPORTANCE: Soy isoflavone supplements are used to treat several chronic diseases, although the data supporting their use are limited. Some data suggest that supplementation with soy isoflavone may be an effective treatment for patients with poor asthma co ... Full text Link to item Cite

Better medicine by default.

Journal article Med Decis Making · February 2014 BACKGROUND: American health care is transitioning to electronic physician ordering. These computerized systems are unique because they allow custom order interfaces. Although these systems provide great benefits, there are also potential pitfalls, as the b ... Full text Link to item Cite

Size matters--nanotechnology and therapeutics in rheumatology and immunology.

Journal article Curr Rheumatol Rev · 2014 Nanotechnology, or the use of technology at the submicron scale, and its application to medicine (nanomedicine) draws from many ideas and technological advancements across myriad fields of materials technology and has improved biomedical understanding. Nan ... Full text Link to item Cite

The pathologic and clinical intersection of atopic and autoimmune disease.

Journal article Curr Allergy Asthma Rep · December 2012 Hypersensitivity reactions of the immune system have been broadly categorized into the atopic and autoimmune depending on whether the antigen triggering the reaction is endogenous (or self) or exogenous, the types of cellular and humoral components involve ... Full text Link to item Cite

Gout, hyperuricemia, and the risk of cardiovascular disease: cause and effect?

Journal article Curr Rheumatol Rep · April 2010 Gout and hyperuricemia have long been suspected to be risk factors for cardiovascular disease. However, studies have frequently failed to distinguish whether these entities have an independent effect on cardiovascular risk or serve as markers for other ris ... Full text Link to item Cite

Thoracic endografting in a patient with hereditary hemorrhagic telangiectasia presenting with a descending thoracic aneurysm.

Journal article J Vasc Surg · February 2010 A 53-year-old woman with no classic risk factors for aneurysm disease presented with the sudden onset of chest pain and dyspnea. A large descending thoracic aortic aneurysm with focal type B dissection was identified and excluded by emergency thoracic endo ... Full text Link to item Cite

T cell large granular lymphocyte leukemia associated with rheumatoid arthritis and neutropenia.

Journal article Clin Immunol · August 2009 T cell large granular lymphocyte leukemia (T-LGL) is a disease characterized by clonal expansion of cytotoxic T cells (CTLs). It generally follows an indolent course and is notable for an association with chronic inflammation, neutropenia and rheumatoid ar ... Full text Link to item Cite