Anushka Palipana

Journal Article Hypertension · February 2025 BACKGROUND: Dietary Approaches to Stop Hypertension (DASH) is a recommended first-line treatment for adults with hypertension, yet adherence to DASH is low. To evaluate the efficacy of a digital health intervention (DHI), compared with attention control, o ... Full text Link to item Cite

Real-world association between ivacaftor initiation and lung function variability: A registry study.

Journal Article Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · February 2025 BackgroundIncreased variability in forced expiratory volume in 1 s of % predicted (FEV1pp) has been associated with accelerated lung function decline in individuals with cystic fibrosis (CF). Lung function variability is a leading predi ... Full text Cite

Secular and modulator-specific drifts in the predictive performance of a rapid lung function decline algorithm: a cystic fibrosis patient registry study

Journal Article Discover Data · September 24, 2024 Full text Cite

A case study of inclusion of rural populations in research: Implications for science and health equity.

Journal Article Clin Transl Sci · August 2024 Prior research highlights that rural populations have been historically underrepresented/excluded from clinical research. The primary objective of this study was to describe the inclusion of rural populations within our research enterprise using Clinical R ... Full text Open Access Link to item Cite

Efficacy of BETTER transitional care intervention for diverse patients with traumatic brain injury and their families: Study protocol of a randomized controlled trial.

Journal Article PLoS One · 2024 OBJECTIVE: The purpose of this study is to examine the efficacy of BETTER (Brain Injury, Education, Training, and Therapy to Enhance Recovery) vs. usual transitional care management among diverse adults with traumatic brain injury (TBI) discharged home fro ... Full text Open Access Link to item Cite

Bayesian two-stage modeling of longitudinal and time-to-event data with an integrated fractional Brownian motion covariance structure.

Journal Article Biometrics · January 2024 It is difficult to characterize complex variations of biological processes, often longitudinally measured using biomarkers that yield noisy data. While joint modeling with a longitudinal submodel for the biomarker measurements and a survival submodel for a ... Full text Cite

Social-environmental phenotypes of rapid cystic fibrosis lung disease progression in adolescents and young adults living in the United States.

Journal Article Environmental advances · December 2023 BackgroundCystic fibrosis (CF) is a genetic disease but is greatly impacted by non-genetic (social/environmental and stochastic) influences. Some people with CF experience rapid decline, a precipitous drop in lung function relative to patient- and ... Full text Cite

Predicting Individualized Lung Disease Progression in Treatment-Naive Patients With Lymphangioleiomyomatosis.

Journal Article Chest · June 2023 BackgroundLung function decline varies significantly in patients with lymphangioleiomyomatosis (LAM), impeding individualized clinical decision-making.Research questionCan we aid individualized decision-making in LAM by developing a dynam ... Full text Cite

Built environment factors predictive of early rapid lung function decline in cystic fibrosis.

Journal Article Pediatric pulmonology · May 2023 BackgroundThe extent to which environmental exposures and community characteristics of the built environment collectively predict rapid lung function decline, during adolescence and early adulthood in cystic fibrosis (CF), has not been examined. Full text Cite

Seasonality, mediation and comparison (SMAC) methods to identify influences on lung function decline.

Journal Article MethodsX · January 2021 This study develops a comprehensive method to assess seasonal influences on a longitudinal marker and compare estimates between cohorts. The method extends existing approaches by (i) combining a sine-cosine model of seasonality with a specialized covarianc ... Full text Cite