Overview
Anyi Mazo-Vargas is originally from Cali, Colombia, where she graduated from the Biology program at Universidad del Valle. She then pursued a master’s degree at the University of Puerto Rico in Mayaguez, focusing on weevil beetles and phylogenetics. After moving to the United States, Anyi worked as a laboratory manager at Duke University in Dr. Buchler’s lab, utilizing luciferases to study the cell cycle of Saccharomyces yeast. These experiences inspired her to pursue a PhD in the Entomology Department at Cornell University, where she combined her knowledge in insects, evolution, and genetics to study butterfly color patterning. At Cornell, she investigated genes involved in wing element patterning and their regulation. She later joined George Washington University as a postdoctoral researcher, working on transgenesis projects in both moths and butterflies.
The AMV Laboratory at Duke employs genetics, functional genomics, and developmental biology approaches to untangle the genetic basis of morphological adaptive traits. Our research aims to dissect the underlying developmental processes and place our findings within a micro- and macro-evolutionary framework. We seek to identify genomic and developmental properties, explaining how adaptive traits such as wing patterns and wing shapes involved in mimicry, camouflage, thermoregulation, and other defense mechanisms develop and evolve.
Current Appointments & Affiliations
Recent Publications
The <i>ivory</i> lncRNA regulates seasonal color patterns in buckeye butterflies.
Journal Article Proceedings of the National Academy of Sciences of the United States of America · October 2024 Long noncoding RNAs (lncRNAs) are transcribed elements increasingly recognized for their roles in regulating gene expression. Thus far, however, we have little understanding of how lncRNAs contribute to evolution and adaptation. Here, we show that a conser ... Full text CiteA long noncoding RNA at the cortex locus controls adaptive coloration in butterflies.
Journal Article Proceedings of the National Academy of Sciences of the United States of America · September 2024 Evolutionary variation in the wing pigmentation of butterflies and moths offers striking examples of adaptation by crypsis and mimicry. The cortex locus has been independently mapped as the locus controlling color polymorphisms in 15 lepidopteran sp ... Full text CiteRecent Grants
Training Program in Developmental and Stem Cell Biology
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2001 - 2027View All Grants