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Anyi Mazo-Vargas

Assistant Professor of Biology
Biology
137 Bio Science Dr, Durham, NC 27708
124 Science Drive - FFSC 3313, Durham, NC 27708

Overview


Anyi Mazo-Vargas is originally from Cali, Colombia, where she graduated from the Biology program at Universidad del Valle. She then pursued a master’s degree at the University of Puerto Rico in Mayaguez, focusing on weevil beetles and phylogenetics. After moving to the United States, Anyi worked as a laboratory manager at Duke University in Dr. Buchler’s lab, utilizing luciferases to study the cell cycle of Saccharomyces yeast. These experiences inspired her to pursue a PhD in the Entomology Department at Cornell University, where she combined her knowledge in insects, evolution, and genetics to study butterfly color patterning. At Cornell, she investigated genes involved in wing element patterning and their regulation. She later joined George Washington University as a postdoctoral researcher, working on transgenesis projects in both moths and butterflies.

The AMV Laboratory at Duke employs genetics, functional genomics, and developmental biology approaches to untangle the genetic basis of morphological adaptive traits. Our research aims to dissect the underlying developmental processes and place our findings within a micro- and macro-evolutionary framework. We seek to identify genomic and developmental properties, explaining how adaptive traits such as wing patterns and wing shapes involved in mimicry, camouflage, thermoregulation, and other defense mechanisms develop and evolve.

Current Duke Appointments & Affiliations


Assistant Professor of Biology · 2024 - Present Biology, Trinity College of Arts & Sciences

Recent Scholarly Works


araucan regulates butterfly wing iridescence by coordinating scale structure and pigmentation.

Journal article Proceedings. Biological sciences · May 2026 Butterfly wings exhibit a remarkable diversity of structural iridescent colours, yet the genetic regulation of iridescence remains poorly understood. Here, we show that the Iroquois-complex transcription factor gene araucan plays a role in modulating wing ... Full text Cite

ABCG transporter knockouts alter integument and eye pigmentation with gene-specific effects on viability in butterflies and moths

Preprint · 2026 ABSTRACT Insects possess remarkable diversity in pigmentation across life stages, generated from a limited number of pigment precursors. ABCG transporters play central roles in pigmentation by mediating the intracellular transport of these precur ... Full text Cite

The <i>ivory</i> lncRNA regulates seasonal color patterns in buckeye butterflies.

Journal article Proceedings of the National Academy of Sciences of the United States of America · October 2024 Long noncoding RNAs (lncRNAs) are transcribed elements increasingly recognized for their roles in regulating gene expression. Thus far, however, we have little understanding of how lncRNAs contribute to evolution and adaptation. Here, we show that a conser ... Full text Cite
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Recent Grants


Genomic, ecological and evolutionary drivers of the elaborate structural color in Parides butterflies

FellowshipPrincipal Investigator · Awarded by Simons Foundation · 2026 - 2031

Training Program in Developmental and Stem Cell Biology

Inst. Training Prgm or CMEMentor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2001 - 2027

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Education


Cornell University · 2020 Ph.D.

External Links


Mazo-Vargas Lab