Scholars@Duke
Arriel Benis

Arriel Benis

Adjunct Associate Professor in the Department of Biomedical Engineering
Biomedical Engineering
101 Science Dr, Durham, NC 27701
ORCID iDhttps://orcid.org/0000-0002-9125-8300

Scholarly Works - Journal articles

"Do It by Myself" or Autonomy, Participation, and Assistive Devices and Technology Needs of Children and Youth With Disabilities: Text Mining Analysis of a National Survey in France.

Journal article JMIR medical informatics · July 2026 BackgroundA 2019 French national online survey explored activity limitations and participation restrictions among children and youth with disabilities for which innovative solutions could help.ObjectiveThe primary aim of this study was to ... Full text Open Access Cite

Preface

Journal article Studies in Health Technology and Informatics · May 21, 2026 Cite

Teaching Applied Artificial Intelligence in Health Schools: An Example from Rouen and Nice Universities in France.

Journal article Studies in health technology and informatics · May 2026 This SaNuRN initiative developed a teaching module on applied AI for health residents, fellows, and CME professionals, responding to the French Ministry of Health's call to integrate digital health education. It covers AI theory, applications across health ... Full text Cite

A cloud-edge reference architecture for intertwining health digital domains.

Journal article Health informatics journal · January 2026 Objective: In the present work, LinkAll is introduced as a novel architectural model designed to enable real-time monitoring and cross-referential data analysis in remote monitoring systems across human, animal, and environmental health domains. Lin ... Full text Open Access Cite

Dynamic machine learning models for predicting cesarean delivery risk in women with no prior cesarean delivery: A retrospective nationwide cohort analysis.

Journal article International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · November 2025 ObjectiveTo develop and validate advanced machine learning (ML) models for predicting unplanned intrapartum cesarean deliveries in women with no previous cesarean delivery, using both static and dynamic clinical data.MethodsA retrospectiv ... Full text Open Access Cite

Preface

Journal article Studies in Health Technology and Informatics · October 2, 2025 Full text Cite

On the Design of a FAIR Data Maturity Model for OneAquaHealth.

Journal article Studies in health technology and informatics · October 2025 The scope of this work is to describe the overall process of assessing the compliance of the main Digital Objects produced in the OneAquaHealth project with the FAIR principles (Findability, Accessibility, Interoperability, and Reusability) via a custom FA ... Full text Cite

AI Scribes in Health Care: Balancing Transformative Potential With Responsible Integration.

Journal article JMIR medical informatics · August 2025 UnlabelledThe administrative burden of clinical documentation contributes to health care practitioner burnout and diverts valuable time away from direct patient care. Ambient artificial intelligence (AI) scribes-also called "digital scribes" or "A ... Full text Open Access Cite

Automated Elicitation of Human and Ecological Health Indicators: An LLM-Based Practical Implementation for One Digital Health.

Journal article Studies in health technology and informatics · August 2025 This paper presents a new method for automating the identification of human and ecological health indicators using the One Digital Health framework, which combines One Health and Digital Health principles. By applying mainly Large Language Models, we condu ... Full text Open Access Cite

Implementing FAIR Principles in Health Terminology Servers: The HeTOP Case Study Hosting ODH-UT.

Journal article Studies in health technology and informatics · May 2025 The compliance of health terminology servers with the FAIR principles is crucial for establishing an interoperable digital health ecosystem that facilitates health data exchange. These servers must maintain high-quality standards while providing persistent ... Full text Cite

Digital Platform for Pediatric Mental Health Support During Armed Conflicts: Development and Usability Study.

Journal article JMIR formative research · December 2024 BackgroundThe prevalence of mental health disorders among children and adolescents presents a significant public health challenge. Children exposed to armed conflicts are at a particularly high risk of developing mental health problems, necessitat ... Full text Open Access Cite

Enhancing Lessons on the Internet of Things in Science, Technology, Engineering, and Medical Education with a Remote Lab.

Journal article Sensors (Basel, Switzerland) · October 2024 Integrating remote Internet of Things (IoT) laboratories into project-based learning (PBL) in higher education institutions (HEIs) while exploiting the approach of technology-enhanced learning (TEL) is a challenging yet pivotal endeavor. Our proposed appro ... Full text Open Access Cite

Empowering healthcare education: A multilingual ontology for medical informatics and digital health (MIMO) integrated to artificial intelligence powered training in smart hospitals.

Journal article Health informatics journal · October 2024 Objective: A comprehensive understanding of professional and technical terms is essential to achieving practical results in multidisciplinary projects dealing with health informatics and digital health. The medical informatics multilingual ontology ... Full text Cite

A Structured Social Media Health Support Program after Bariatric Surgery.

Journal article Applied clinical informatics · October 2024 BackgroundSocial media networks have been found to provide emotional, instrumental, and social support, which may contribute to improved adherence to postbariatric surgery care recommendations.ObjectivesThis study aimed to evaluate the im ... Full text Open Access Cite

Initiating a One Digital Health Unified Terminology (ODH-UT) to Facilitate Community Expansion.

Journal article Studies in health technology and informatics · August 2024 One Digital Health (ODH) merges the Digital Health and One Health approaches to create a comprehensive framework for future health ecosystems. In this rapidly evolving field, a standardized vocabulary is not just a convenience, but a necessity to ensure ef ... Full text Cite

Enhancing Technology-Focused Entrepreneurship in Higher Education Institutions Ecosystem: Implementing Innovation Models in International Projects

Journal article Education Sciences · July 1, 2024 Innovation models are key to fostering technology-focused entrepreneurship in higher education institutions (HEIs). These models create dynamic environments that encourage collaboration, creativity, and problem-solving skills among students and faculty. HE ... Full text Cite

Digital Health Education for the Future: The SaNuRN (Santé Numérique Rouen-Nice) Consortium's Journey.

Journal article JMIR medical education · April 2024 SaNuRN is a five-year project by the University of Rouen Normandy (URN) and the Côte d’Azur University (CAU) consortium to optimize digital health education for medical and paramedical students, professionals, and administrators. The project includes a ski ... Full text Open Access Cite

Sharing Digital Health Educational Resources in a One-Stop Shop Portal: Tutorial on the Catalog and Index of Digital Health Teaching Resources (CIDHR) Semantic Search Engine.

Journal article JMIR medical education · March 2024 BackgroundAccess to reliable and accurate digital health web-based resources is crucial. However, the lack of dedicated search engines for non-English languages, such as French, is a significant obstacle in this field. Thus, we developed and imple ... Full text Open Access Cite

Understanding metric-related pitfalls in image analysis validation.

Journal article ArXiv · February 23, 2024 Validation metrics are key for the reliable tracking of scientific progress and for bridging the current chasm between artificial intelligence (AI) research and its translation into practice. However, increasing evidence shows that particularly in image an ... Link to item Cite

Metrics reloaded: recommendations for image analysis validation.

Journal article Nature methods · February 2024 Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. In biomedical image analysis, chosen performance metrics often do not reflect the domain interest, and thus fail to adequately measure ... Full text Open Access Cite

Understanding metric-related pitfalls in image analysis validation.

Journal article Nature methods · February 2024 Validation metrics are key for tracking scientific progress and bridging the current chasm between artificial intelligence research and its translation into practice. However, increasing evidence shows that, particularly in image analysis, metrics are ofte ... Full text Open Access Cite

International scientific communication on COVID-19 data: management pitfalls understanding.

Journal article Journal of public health (Oxford, England) · February 2024 BackgroundDuring the pandemic, countries utilized various forms of statistical estimations of coronavirus disease-2019 (COVID-19) impact. Differences between databases make direct comparisons and interpretations of data in different countries a ch ... Full text Cite

Novel ways to analyse and cope alert-fatigue phenomenon in intensive care units

Journal article ITM Web of Conferences · 2024 In Intensive Care Units (ICUs), patient monitoring relies on many devices configured to trigger alarms when specific physiological parameters surpass pre-established thresholds, including metrics like heart rate and oxygen saturation. Nevertheless, ... Full text Cite

Alert-Grouping: Smart Personalization of Monitoring System Thresholds to Help Healthcare Teams Struggle with Alarm Fatigue in Intensive Care.

Journal article Journal of medical systems · November 2023 In Intensive Care Units (ICUs), patients are monitored using various devices that generate alerts when specific metrics, such as heart rate and oxygen saturation, exceed predetermined thresholds. However, these alerts can be inaccurate and lead to alert fa ... Full text Cite

Telehealth Ecosystems in Practice

Journal article · October 20, 2023 Full text Cite

Leveraging Data and Technology to Enhance Interdisciplinary Collaboration and Health Outcomes.

Journal article Yearbook of medical informatics · August 2023 ObjectiveTo give an overview of recent research and propose a selection of best papers published in 2022 in Informatics for One Health.MethodsAn extensive search using PubMed and Web of Science was conducted to identify peer-reviewed arti ... Full text Open Access Cite

Digital Emergency Management for a Complex One Health Landscape: the Need for Standardization, Integration, and Interoperability.

Journal article Yearbook of medical informatics · August 2023 ObjectivePlanning reliable long-term planning actions to handle disruptive events requires a timely development of technological infrastructures, as well as the set-up of focused strategies for emergency management. The paper aims to highlight the ... Full text Open Access Cite

The Need for Green and Responsible Medical Informatics and Digital Health: Looking Forward with One Digital Health.

Journal article Yearbook of medical informatics · August 2023 One Health is an important initiative to view the world in a more integrative sense of our health and environment. Digital Health provides essential support to all of us as healthcare professionals and customers. One Digital Health (ODH) combines both One ... Full text Open Access Cite

One Digital Health Intervention for Monitoring Human and Animal Welfare in Smart Cities: Viewpoint and Use Case.

Journal article JMIR medical informatics · May 2023 Smart cities and digital public health are closely related. Managing digital transformation in urbanization and living spaces is challenging. It is critical to prioritize the emotional and physical health and well-being of humans and their animals in the d ... Full text Open Access Cite

EFMI

Journal article Yearbook of Medical Informatics · December 4, 2022 Full text Cite

One Digital Health for more FAIRness.

Journal article Methods of information in medicine · December 2022 BackgroundOne Digital Health (ODH) aims to propose a framework that merges One Health's and Digital Health's specific features into an innovative landscape. FAIR (Findable, Accessible, Interoperable, and Reusable) principles consider applications ... Full text Open Access Cite

Early Detection and Control of the Next Epidemic Wave Using Health Communications: Development of an Artificial Intelligence-Based Tool and Its Validation on COVID-19 Data from the US.

Journal article International journal of environmental research and public health · November 2022 Social media networks highly influence on a broad range of global social life, especially in the context of a pandemic. We developed a mathematical model with a computational tool, called EMIT (Epidemic and Media Impact Tool), to detect and control pandemi ... Full text Open Access Cite

Medical informatics and digital health multilingual ontology (MIMO): A tool to improve international collaborations.

Journal article International journal of medical informatics · November 2022 BackgroundEven if English is the leading language for international communication, it is essential to keep in mind that research runs at the local level by local teams generally communicating in their local/national language, especially in Europe ... Full text Cite

Digital Health Multilingual Ontology to Index Teaching Resources.

Journal article Studies in health technology and informatics · August 2022 The aim of this paper is to present the use of Medical Informatics Multilingual Ontology (MIMO) to index digital health resources that are (and will be) included in SaNuRN (project to teach digital health). MIMO currently contains 1,379 concepts and is int ... Full text Cite

Quantitative and qualitative analysis of the quality of life of Type 1 diabetes patients using insulin pumps and of those receiving multiple daily insulin injections.

Journal article Health and quality of life outcomes · August 2022 IntroductionInsulin pump therapy represents an alternative to multiple daily injections and can improve glycemic control and quality of life (QoL) in Type 1 diabetes mellitus (T1DM) patients. We aimed to explore the differences and factors related ... Full text Open Access Cite

Trends in the Prevalence of Chronic Medication Use Among Children in Israel Between 2010 and 2019: Protocol for a Retrospective Cohort Study.

Journal article JMIR research protocols · August 2022 BackgroundPrescription of psychostimulants has significantly increased in most countries worldwide for both preschool and school-aged children. Understanding the trends of chronic medication use among children in different age groups and from diff ... Full text Open Access Cite

Accident & Emergency Informatics and One Digital Health.

Journal article Yearbook of medical informatics · August 2022 ObjectivesClimate changes are the major challenge in public and individual health, as they modify the ecosystem and yield contagious diseases from animal to human. Furthermore, we notice the rapid development of elderly, changing the population de ... Full text Open Access Cite

WikiMeSH: Multi Lingual MeSH Translations via Wikipedia.

Journal article Studies in health technology and informatics · May 2022 ObjectiveThe aim of this paper is to propose an extended translation of the MeSH thesaurus based on Wikipedia pages.MethodsA mapping was realized between each MeSH descriptor (preferred terms and synonyms) and corresponding Wikipedia page ... Full text Cite

Social Media and the Internet of Things for Emergency and Disaster Medicine Management.

Journal article Studies in health technology and informatics · May 2022 Social Media and the Internet of Things are nowadays full and strong components of day-to-day life worldwide. Both allow communicating with others 24 hours a day, 7 days a week without distance limitations. During the last decade, on-site citizens have sha ... Full text Cite

Intergenerational knowledge management in a cutting-edge Israeli industry: Visions and challenges.

Journal article PloS one · January 2022 Knowledge management is a multifaceted, complex, end-to-end organizational process dealing with collecting and using data, information, and knowledge generated by a group of individuals. The current study examines the changes required in companies' quality ... Full text Open Access Cite

Data-Driven Decision Making and Proactive Citizen-Scientist Communication: A Cross-Sectional Study on COVID-19 Vaccination Adherence.

Journal article Vaccines · November 2021 Due to the severe impact of COVID-19 on public health, rollout of the vaccines must be large-scale. Current solutions are not intended to promote an active collaboration between communities and public health researchers. We aimed to develop a digital platf ... Full text Open Access Cite

One Digital Health Is FAIR.

Journal article Studies in health technology and informatics · November 2021 The One Digital Health framework aims at transforming future health ecosystems and guiding the implementation of a digital technologies-based systemic approach to caring for humans' and animals' health in a managed surrounding environment. To integrate and ... Full text Cite

Reasons for Utilizing Telemedicine during and after the COVID-19 Pandemic: An Internet-Based International Study.

Journal article Journal of clinical medicine · November 2021 The COVID-19 pandemic challenges healthcare services. Concomitantly, this pandemic had a stimulating effect on technological expansions related to telehealth and telemedicine. We sought to elucidate the principal patients' reasons for using telemedicine du ... Full text Open Access Cite

Statin Therapy for Primary Prevention in the Elderly and Its Association with New-Onset Diabetes, Cardiovascular Events, and All-Cause Mortality.

Journal article The American journal of medicine · May 2021 PurposeThis study assessed associations of the use of statins for primary prevention with cardiovascular outcomes among adults ages ≥70 years.MethodsIn a retrospective population-based cohort study, new users of statins without cardiovasc ... Full text Cite

Training the Next Industrial Engineers and Managers about Industry 4.0: A Case Study about Challenges and Opportunities in the COVID-19 Era.

Journal article Sensors (Basel, Switzerland) · April 2021 Training the next generation of industrial engineers and managers is a constant challenge for academia, given the fast changes of industrial technology. The current and predicted development trends in applied technologies affecting industry worldwide as fo ... Full text Open Access Cite

Reasons for Taking the COVID-19 Vaccine by US Social Media Users.

Journal article Vaccines · March 2021 Political and public health leaders promoting COVID-19 vaccination should identify the most relevant criteria driving the vaccination decision. Social media is increasingly used as a source of vaccination data and as a powerful communication tool to increa ... Full text Open Access Cite

Social Media Engagement and Influenza Vaccination During the COVID-19 Pandemic: Cross-sectional Survey Study.

Journal article Journal of medical Internet research · March 2021 BackgroundVaccines are one of the most important achievements of modern medicine. However, their acceptance is only partial, with vaccine hesitancy and refusal representing a major health threat. Influenza vaccines have low compliance since repeat ... Full text Open Access Cite

An Early Stage Researcher's Primer on Systems Medicine Terminology.

Journal article Network and systems medicine · February 2021 Background: Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an e ... Full text Open Access Cite

One Digital Health: A Unified Framework for Future Health Ecosystems.

Journal article Journal of medical Internet research · February 2021 One Digital Health is a proposed unified structure. The conceptual framework of the One Digital Health Steering Wheel is built around two keys (ie, One Health and digital health), three perspectives (ie, individual health and well-being, population and soc ... Full text Open Access Cite

Change in Threads on Twitter Regarding Influenza, Vaccines, and Vaccination During the COVID-19 Pandemic: Artificial Intelligence-Based Infodemiology Study.

Journal article JMIR infodemiology · January 2021 BackgroundDiscussions of health issues on social media are a crucial information source reflecting real-world responses regarding events and opinions. They are often important in public health care, since these are influencing pathways that affect ... Full text Open Access Cite

Communication Behavior Changes Between Patients With Diabetes and Healthcare Providers Over 9 Years: Retrospective Cohort Study.

Journal article Journal of medical Internet research · August 2020 BackgroundHealth organizations and patients interact over different communication channels and are harnessing digital communications for this purpose. Assisting health organizations to improve, adapt, and introduce new patient-health care practiti ... Full text Open Access Cite

Network and Systems Medicine: Position Paper of the European Collaboration on Science and Technology Action on Open Multiscale Systems Medicine.

Journal article Network and systems medicine · January 2020 Introduction: Network and systems medicine has rapidly evolved over the past decade, thanks to computational and integrative tools, which stem in part from systems biology. However, major challenges and hurdles are still present regarding validation ... Full text Open Access Cite

A Multi-Lingual Dictionary for Health Informatics as an International Cooperation Pillar.

Journal article Studies in health technology and informatics · July 2019 Even if, English is generally used for international communication, it is essential to keep in mind that research is running at the local level by local teams generally communicating in their local/national language. Bearing these in mind, the "European Fe ... Full text Cite

A Social Networks Data Historian Supporting Research in Emergency & Disaster Medicine and Management.

Journal article Studies in health technology and informatics · January 2019 The aim of this initial research is to show that data and information collected from Internet Social Networks support the understanding of individual and collective behaviors which can help emergencies and disasters managers to mitigate and to improve prep ... Cite

Incident gout and chronic Kidney Disease: healthcare utilization and survival.

Journal article BMC rheumatology · January 2019 BackgroundUncontrolled gout can cause significant joint and organ damage and has been associated with impairments in quality of life and high economic cost. Gout has also been associated with other comorbid diseases, such as chronic kidney disease ... Full text Open Access Cite

Population-based cohort of 500 patients with Gaucher disease in Israel.

Journal article BMJ open · January 2019 ObjectiveTo characterise a population-based cohort of patients with Gaucher disease (GD) in Israel relative to the general population and describe sociodemographic and clinical differences by disease severity (ie, enzyme replacement therapy [ERT] ... Full text Open Access Cite

Patterns of Patients' Interactions With a Health Care Organization and Their Impacts on Health Quality Measurements: Protocol for a Retrospective Cohort Study.

Journal article JMIR research protocols · November 2018 BackgroundData collected by health care organizations consist of medical information and documentation of interactions with patients through different communication channels. This enables the health care organization to measure various features of ... Full text Cite

Administrative health databases for addressing emerging issues in adults with CHD: a systematic review.

Journal article Cardiology in the young · June 2018 The need for population-based studies of adults with CHD has motivated the growing use of secondary analyses of administrative health data in a variety of jurisdictions worldwide. We aimed at systematically reviewing all studies using administrative health ... Full text Cite

Healthcare Informatics Project-Based Learning: An Example of a Technology Management Graduation Project Focusing on Veterinary Medicine.

Journal article Studies in health technology and informatics · January 2018 Teaching Healthcare Informatics using Project-Based Learning focuses students on active and inquiry-based learning and allows them to gain some knowledge and skills in the field. From the perspective of Technology Management, which is at the cross-road of ... Full text Cite

Identification and Description of Healthcare Customer Communication Patterns Among Individuals with Diabetes in Clalit Health Services: A Retrospective Database Study.

Journal article Studies in health technology and informatics · January 2017 HMOs record medical data and their interactions with patients. Using this data we strive to identify sub-populations of healthcare customers based on their communication patterns and characterize these sub-populations by their socio-demographic, medical, t ... Full text Cite

Dynamics of circulating hypoxia-mediated miRNAs and tumor response in patients with high-grade glioma treated with bevacizumab.

Journal article Journal of neurosurgery · October 2016 OBJECTIVE Bevacizumab is an antiangiogenic agent under investigation for use in patients with high-grade glioma. It produces a high rate of radiological response; however, this response should be interpreted with caution because it may reflect normalizatio ... Full text Cite

Obesity or smoking: Which factor contributes more to the incidence of myocardial infarction?

Journal article European journal of internal medicine · July 2016 ObjectiveComparing the contributions of smoking and obesity to the risk of myocardial infarction (MI) can help prioritize behavioral modifications. The objective of this study was to determine the relative risk of smoking, obesity and the joint bu ... Full text Cite

Stimulant use for ADHD and relative age in class among children in Israel.

Journal article Pharmacoepidemiology and drug safety · June 2016 BackgroundDiagnosis of children with attention-deficit/hyperactivity disorder (ADHD) is increasing. The present study sought to identify characteristics and medication treatment patterns of children with ADHD and compare them by relative age in cl ... Full text Open Access Cite

Sex-specific prediction of interferon beta therapy response in relapsing-remitting multiple sclerosis.

Journal article Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · June 2015 Multiple sclerosis (MS) is a demyelinating disorder predominantly affecting young people. Currently, interferon beta (IFNβ) is a common treatment for MS. Despite a large effort in recent years, valid biomarkers with predictive value for clinical outcome an ... Full text Cite

Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis.

Journal article FASEB journal : official publication of the Federation of American Societies for Experimental Biology · September 2005 The molecular mechanisms by which obesity increases the risk of cardiovascular diseases are poorly understood. The purpose of this study was to identify candidate biomarkers overexpressed in adipose tissue of obese subjects that could link expanded fat mas ... Full text Cite

Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects.

Journal article FASEB journal : official publication of the Federation of American Societies for Experimental Biology · November 2004 Adipose tissue produces inflammation and immunity molecules suspected to be involved in obesity-related complications. The pattern of expression and the nutritional regulation of these molecules in humans are poorly understood. We analyzed the gene express ... Full text Cite

In vivo epinephrine-mediated regulation of gene expression in human skeletal muscle.

Journal article The Journal of clinical endocrinology and metabolism · May 2004 The stress hormone epinephrine produces major physiological effects on skeletal muscle. Here we determined skeletal muscle mRNA expression profiles before and during a 6-h epinephrine infusion performed in nine young men. Stringent statistical analysis of ... Full text Cite

Improving classification of microarray data using prototype-based feature selection

Journal article ACM SIGKDD Explorations Newsletter · December 2003 This paper addresses the problem of improving accuracy in the machine-learning task of classification from microarray data. One of the known issues specifically related to microarray data is the large number of inputs (genes) versus the small numbe ... Full text Cite