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Arthur Greenberg

Professor Emeritus of Medicine
Medicine, Nephrology
Duke Box 2747, Durham, NC 27710
2424 Erwin Road, Suite 605, Durham, NC 27705

Featured Works


Treatment of chronic hyponatremia: now we know how, but do we know when or if?

Journal article J Am Soc Nephrol · April 2010 Featured Publication Full text Link to item Cite

Effect of dipyridamole plus aspirin on hemodialysis graft patency.

Journal article N Engl J Med · May 21, 2009 Featured Publication BACKGROUND: Arteriovenous graft stenosis leading to thrombosis is a major cause of complications in patients undergoing hemodialysis. Procedural interventions may restore patency but are costly. Although there is no proven pharmacologic therapy, dipyridamo ... Full text Link to item Cite

When is it appropriate to use vasopressin receptor antagonists?

Journal article J Am Soc Nephrol · June 2008 Featured Publication Hyponatremia is a common and challenging disorder. The mainstays of treatment until recently were water restriction and hypertonic saline. The first nonpeptide vasopressin receptor antagonist (VRA) is now approved by the US Food and Drug Administration for ... Full text Link to item Cite

Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized controlled trial.

Journal article JAMA · May 14, 2008 Featured Publication CONTEXT: The arteriovenous fistula is the preferred type of vascular access for hemodialysis because of lower thrombosis and infection rates and lower health care expenditures compared with synthetic grafts or central venous catheters. Early failure of fis ... Full text Link to item Cite

Tolvaptan, an oral vasopressin V2 receptor antagonist for heart failure?

Journal article Am J Kidney Dis · December 2007 Featured Publication Full text Link to item Cite

Hyponatremia treatment guidelines 2007: expert panel recommendations.

Journal article Am J Med · November 2007 Featured Publication Although hyponatremia is a common, usually mild, and relatively asymptomatic disorder of electrolytes, acute severe hyponatremia can cause substantial morbidity and mortality, particularly in patients with concomitant disease. In addition, overly rapid cor ... Full text Link to item Cite

Familial hypocalciuric hypercalcemia in the donor and recipient of a living related donor kidney transplant.

Journal article Am J Transplant · March 2007 Featured Publication Familial hypocalciuric hypercalcemia (FHH) is caused by heterozygous inactivation of the calcium-sensing receptor, which is notably expressed in parathyroid and kidney. FHH is characterized by asymptomatic hypercalcemia and hypophosphatemia and confers min ... Full text Link to item Cite

Postinfectious glomerulonephritis in renal allograft recipients.

Journal article Transplantation · November 15, 2006 Featured Publication Postinfectious glomerulonephritis (PIGN) is a rare etiology of de novo glomerulonephritis following kidney transplantation. To date, there have only been eight cases reported in the literature. We report an additional three patients transplanted at our ins ... Full text Link to item Cite

Vasopressin receptor antagonists.

Journal article Kidney Int · June 2006 Featured Publication The first non-peptide vasopressin receptor antagonist (VRA) was recently approved by the United States Food and Drug Administration, and several others are now in late stages of clinical development. Phase 3 trials indicate that these agents predictably re ... Full text Link to item Cite

Kidney disease other than renal crisis in patients with diffuse scleroderma.

Journal article J Rheumatol · April 2005 Featured Publication OBJECTIVE: To determine the frequency and severity of kidney abnormalities in patients with diffuse scleroderma. METHODS: All patients with diffuse scleroderma seen at the University of Pittsburgh between 1972 and 1993 were included in the study. Kidney fu ... Link to item Cite

Intravenous immunoglobulin and plasmapheresis in acute humoral rejection: experience in renal allograft transplantation.

Journal article Hum Immunol · April 2005 Featured Publication Acute humoral rejection (AHR) in kidney transplantation is associated with higher rates of allograft loss when compared with acute cellular rejection (ACR). Treatment with intravenous immunoglobulin (IVIG) combined with plasmapheresis (PP) has been used re ... Full text Link to item Cite

Hyperkalemia: a review.

Journal article J Intensive Care Med · 2005 Featured Publication Potassium is the principal intracellular cation, and maintenance of the distribution of potassium between the intracellular and the extracellular compartments relies on several homeostatic mechanisms. When these mechanisms are perturbed, hypokalemia or hyp ... Full text Link to item Cite

Diuretic complications.

Journal article Am J Med Sci · January 2000 Featured Publication BACKGROUND: Diuretics are widely used and generally safe, but like any therapeutic agents, they may cause side effects. METHODS: A review of recent literature pertaining to diuretic usage was performed, with emphasis on specific reports of side effects. Re ... Link to item Cite

Hyperkalemia in hospitalized patients: causes, adequacy of treatment, and results of an attempt to improve physician compliance with published therapy guidelines.

Journal article Arch Intern Med · April 27, 1998 Featured Publication BACKGROUND: Hyperkalemia is a common, potentially life-threatening disorder. Electrocardiograms are considered to be sensitive indicators of the presence of hyperkalemia. Since the treatment of hyperkalemia involves relatively few maneuvers and because its ... Full text Link to item Cite

Hypernatremia in hospitalized patients.

Journal article Ann Intern Med · January 15, 1996 Featured Publication OBJECTIVE: To determine the incidence, clinical characteristics, and outcome for general medical-surgical hospital patients with hypernatremia. DESIGN: A prospective cohort study. SETTING: A 942-bed urban university hospital. PATIENTS: All patients who dev ... Full text Link to item Cite

Hemoperitoneum complicating chronic peritoneal dialysis: single-center experience and literature review.

Journal article Am J Kidney Dis · March 1992 Featured Publication Hemoperitoneum is a well-recognized, if uncommon, complication of chronic peritoneal dialysis. In this review of 424 patients maintained on peritoneal dialysis at a single center during an 11-year period, 26 patients (6.1%) developed one or more episodes o ... Full text Link to item Cite

Cyclosporine nephrotoxicity in cardiac allograft patients--a seven-year follow-up.

Journal article Transplantation · October 1990 Featured Publication Renal function was observed retrospectively in a population of 228 adults who underwent a cardiac allograft at the University of Pittsburgh from June 1980 through June 1987, survived a minimum of one year, and received cyclosporine. Renal function was dete ... Full text Link to item Cite

Variant of Bartter's syndrome with a distal tubular rather than loop of Henle defect.

Journal article Nephron · 1988 Featured Publication A 19-year-old normotensive patient had all of the clinical features of Bartter's syndrome: hypokalemia, elevated renin and aldosterone levels and increased excretion of prostaglandin E. In contrast to the patients described by Bartter, the patient had a no ... Full text Link to item Cite

Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant recipients.

Journal article Am J Kidney Dis · January 1987 Featured Publication To characterize the two forms of cyclosporine nephrotoxicity, we examined renal function in the immediate and late postoperative periods after cardiac transplantation. Moderate azotemia occurred during the first postoperative week in 58% of 43 cyclosporine ... Full text Link to item Cite