Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., University of North Carolina at Chapel Hill 1990
• 

  Duke Appointment History

  • Associate Research Professor in the Institute for Genome Sciences & Policy, Institutes and Centers, School of Medicine 2013 - 2014
  • Associate Research Professor in the Institute for Genome Sciences & Policy, Institutes and Centers, School of Medicine 2009 - 2013
• Research
• 

  Selected Grants

  • Postdoctoral Training in Genomic Medicine Research awarded by National Institutes of Health 2017 - 2022
  • Identification of Novel Bioactive Lipid Metabolites for Predicting Liver-related Outcomes in Persons Co-Infected with HIV and HCV awarded by National Institutes of Health 2017 - 2022
  • Control of COPII vesicle trafficking by intracellular protein glycosylation awarded by National Institutes of Health 2017 - 2021
  • Cell signaling through O-GlcNAc reader proteins awarded by National Institutes of Health 2016 - 2021
  • Novel tissue injury regulation at an organ-organ junction awarded by National Institutes of Health 2016 - 2021
  • Role of Cell Adhesion and the Cytoskeleton in Epidermal Integrity awarded by National Institutes of Health 2015 - 2020
  • Proteomic Signatures of Space Radiation Induced Cardiovascular Degeneration awarded by National Aeronautics and Space Administration 2016 - 2020
  • Qualification of Prognostic and Diagnostic Biomarkers of Knee Osteoarthritis awarded by National Institutes of Health 2017 - 2020
  • Metabolomic Signatures Predictive of Outcomes to Treatments for Major Depression awarded by National Institutes of Health 2016 - 2020
  • Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer awarded by National Institutes of Health 2018 - 2019
  • Differentiation Induced Changes in Centrosomes and Microtubule Organization awarded by National Institutes of Health 2014 - 2019
  • Inhibition of Wnt/B-Catenin Signaling in Colorectal Cancer Therapy awarded by National Institutes of Health 2013 - 2019
  • Enzymology of Chlamydial Pathogenesis awarded by National Institutes of Health 2013 - 2019
  • Analysis of Hepatic Tissues using Tandem Mass Spectrometry and the Biocrates p180 Kit awarded by Gilead Sciences, Inc. 2018
  • Quantitative Analysis of the Postsynaptic Inhibitory Complex In Vivo awarded by National Institutes of Health 2015 - 2017
  • Kinase Target of Diverse Cell Surface Receptors in Cancer Invasion and Metastasis awarded by National Institutes of Health 2011 - 2017
  • Aptamers as Proteomic Tools for Pancreatic Cancer Biomarker Identification awarded by National Institutes of Health 2015 - 2016
  • Instrumentation for Quantitative Phosphoproteomics and Acetylomics awarded by National Institutes of Health 2014 - 2015
  • Prevention of Temporal Lobe Epilepsy awarded by National Institutes of Health 2012 - 2014
  • Truncated GLI1 In Glioblastoma awarded by National Institutes of Health 2014
  • Proteomic Profiling of Human Heart Tissue Exposed to Microgravity awarded by National Aeronautics and Space Administration 2012 - 2013
  • S-nitrosothiol-regulated pathways in acute lung injury awarded by National Institutes of Health 2010 - 2013
  • Molecular mechanisms of chemoresistance in breast cancer awarded by National Institutes of Health 2010 - 2012
  • The effects of Nlrp12 and IL-1b in inflammatory disorders awarded by National Institutes of Health 2010 - 2012
  • Mapping the Architecture of Cancer Signaling Pathways awarded by National Institutes of Health 2009 - 2012
  • Quantitative and Qualitative Differential Expression Proteomics awarded by National Institutes of Health 2010 - 2011
• Publications & Artistic Works
• 

  Selected Publications

  • Book Sections

    • Millington, DS, Zhang, H, Arthur Moseley, M, Will Thompson, J, and Smith, P. "Direct Solvent Extraction and Analysis of Biomarkers in Dried Blood Spots Using a Flow-Through Autosampler." In Dried Blood Spots: Applications and Techniques, 314-324. June 30, 2014.  Full Text
    • Moseley, MA. "Quantitative Proteomics in Genomic Medicine." In Genomic and Personalized Medicine, 155-165. August 29, 2013.  Full Text

  • Conference Papers

    • Kraus, V, Catterall, J, Soderblom, E, Moseley, M, and Suchindran, S. "Development of a serum biomarker panel highly predictive of knee osteoarthritis progression." April 2016.  Full Text
    • Kraus, V, Catterall, J, Soderblom, E, Moseley, M, and Suchindran, S. "Development of a serum biomarker panel highly predictive of a knee osteoarthritis diagnosis." April 2016.  Full Text
    • Foster, MW, Gwinn, WM, Kelly, FL, Brass, DM, Thompson, JW, Moseley, MA, Morgan, DL, and Palmer, SM. "Proteomic Analysis Reveals Significant Epithelial Remodeling After In Vitro Exposure To Diacetyl Vapor." 2016.  Link to Item
    • Foster, MW, Thompson, JW, Brass, DM, Moseley, MA, Morgan, DL, and Palmer, SM. "Plasma Metabolomics Analysis Identifies Candidate Biomarkers Of Flavoring-Induced Bronchiolitis Obliterans." 2016.  Link to Item
    • Kazi, Z, Berrier, K, Lu, C, Bali, D, Will Thompson, J, Arthur Moseley, M, and Kishnani, P. "Proteomics to identify signature proteins in patients likely to mount an immune response to enzyme replacement therapy in infantile Pompe disease." February 2015.  Full Text
    • Quinones, QJ, Ma, Q, Zhang, Z, Henao, R, Soderblom, E, Moseley, MA, Newgard, C, Drew, K, Barnes, BM, and Podgoreanu, MV. "Proteomic Profiling Reveals Reduction in Electron Transport Chain Proteins in the Hearts of Hibernating Arctic Ground Squirrels Compared with Rats after Surgical Ischemia and Reperfusion: A Convergence of Mammalian Cardio-protective Strategies." November 25, 2014.  Link to Item
    • Figueiredo-Freitas, C, Foster, MW, Nogueira, L, Liang, J, Yamashita, A, Dulce, R, Thompson, JW, Hare, JM, Moseley, MA, Sorenson, MM, and Pinto, JR. "S-Nitrosylation Decreases Ca2+ Sensitivity and Actomyosin ATPase Activity of Contractile Proteins in Cardiac Myofibrils." January 29, 2013.  Full Text  Link to Item
    • Naggie, S, Osinusi, A, Himmel, T, Lucas, J, Thompson, JW, Dubois, LG, Moseley, MA, Clark, PJ, Kottilil, S, and Patel, K. "Targeted proteomics signature identifies corticosteroid binding globulin peptides as highly predictive of treatment response in IL28B unfavorable genotype patients." October 2012.  Link to Item
    • Foster, M, Thompson, JW, Forrester, M, Sha, Y, Bowles, D, Moseley, MA, and Marshall, H. "Quantitative proteomics of the cytokine-modulated NOS2 interactome in airway epithelial cells." July 15, 2012.  Full Text  Link to Item
    • Philipp, M, Soderblom, EJ, Thompson, JW, Caron, MG, and Moseley, MA. "A Label-free Quantitative Phosphoproteomic Platform To Assess The Phosphorylation State Of A Complex Sample." March 2011.  Link to Item
    • Foster, MW, Potts, EN, Soderblom, EJ, Yang, Z, Gooden, DM, Moseley, MA, Foster, WM, and Que, LG. "Systemic And/Or Local Aerosol Inhibition Of S-Nitrosoglutathione Reductase (GSNOR) Ameliorates Physiologic, Biologic, And Proteomic Phenotypes In An Allergic Mouse Model Of Inflammatory Airway Disease." 2011.  Link to Item
    • Foster, MW, Yang, Z, Thompson, JW, Ball, CH, Turner, M, Moseley, MA, and Que, LG. "A Proteomic Investigation Of GSNOR-Regulated Pathways In Cytokine-Stimulated Mouse Alveolar Macrophages." 2011.  Link to Item
    • III, PV, Thompson, JW, Soderblom, EJ, Foster, M, Burns, VA, Rogers, JG, Milano, CA, Moseley, MA, and Bowles, DE. "Ischemic Human Heart Failure is Associated With Decreased Phosphorylation of Pyruvate Dehydrogenase and Triosephosphate Isomerase: Proteomic Evidence Supporting Carbohydrate Utilization Preference in the End-Stage Failing Ischemic Heart." November 23, 2010.  Link to Item
    • Tutaeva, V, Thompson, JW, Foster, MW, Moseley, MA, Holly, SP, Delahunty, M, Parise, LV, and Telen, MJ. "S-Nitrosylation of Rap1and Relationship to Rap1 Activity and Disease Status In SCD." November 19, 2010.  Link to Item
    • Patel, K, Lucas, J, Thompson, JW, Moseley, MA, Uzarski, DM, Tillmann, HL, Califf, RM, McCarthy, J, and McHutchison, JG. "HIGH PREDICTIVE ACCURACY OF AN UNBIASED PROTEOMIC PROFILE TO PREDICT SUSTAINED VIROLOGIC RESPONSE IN GENOTYPE 1 CHRONIC HEPATITIS C PATIENTS." October 2008.  Link to Item

  • Journal Articles

    • Hardison, RL, Heimlich, DR, Harrison, A, Beatty, WL, Rains, S, Moseley, MA, Thompson, JW, Justice, SS, and Mason, KM. "Transient Nutrient Deprivation Promotes Macropinocytosis-Dependent Intracellular Bacterial Community Development." Msphere 3, no. 5 (September 12, 2018).  Full Text
    • Juvvadi, PR, Moseley, MA, Hughes, CJ, Soderblom, EJ, Lennon, S, Perkins, SR, Thompson, JW, Geromanos, SJ, Wildgoose, J, Richardson, K, Langridge, JI, Vissers, JPC, and Steinbach, WJ. "Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs." Journal of Proteome Research 17, no. 2 (February 2018): 780-793.  Full Text
    • Moseley, MA, Hughes, CJ, Juvvadi, PR, Soderblom, EJ, Lennon, S, Perkins, SR, Thompson, JW, Steinbach, WJ, Geromanos, SJ, Wildgoose, J, Langridge, JI, Richardson, K, and Vissers, JPC. "Scanning Quadrupole Data-Independent Acquisition, Part A: Qualitative and Quantitative Characterization." Journal of Proteome Research 17, no. 2 (February 2018): 770-779.  Full Text
    • Bowden, JA, Heckert, A, Ulmer, CZ, Jones, CM, Koelmel, JP, Abdullah, L, Ahonen, L, Alnouti, Y, Armando, AM, Asara, JM, Bamba, T, Barr, JR, Bergquist, J, Borchers, CH, Brandsma, J, Breitkopf, SB, Cajka, T, Cazenave-Gassiot, A, Checa, A, Cinel, MA, Colas, RA, Cremers, S, Dennis, EA, Evans, JE, Fauland, A, Fiehn, O, Gardner, MS, Garrett, TJ, Gotlinger, KH, Han, J, Huang, Y, Neo, AH, Hyötyläinen, T, Izumi, Y, Jiang, H, Jiang, H, Jiang, J, Kachman, M, Kiyonami, R, Klavins, K, Klose, C, Köfeler, HC, Kolmert, J, Koal, T, Koster, G, Kuklenyik, Z, Kurland, IJ, Leadley, M, Lin, K, Maddipati, KR, McDougall, D, Meikle, PJ, Mellett, NA, Monnin, C, Moseley, MA, Nandakumar, R, Oresic, M, Patterson, R, Peake, D, Pierce, JS, Post, M, Postle, AD, Pugh, R, Qiu, Y, Quehenberger, O, Ramrup, P, Rees, J, Rembiesa, B, Reynaud, D, Roth, MR, Sales, S, Schuhmann, K, Schwartzman, ML, Serhan, CN, Shevchenko, A, Somerville, SE, St John-Williams, L, Surma, MA, Takeda, H, Thakare, R, Thompson, JW, Torta, F, Triebl, A, Trötzmüller, M, Ubhayasekera, SJK, Vuckovic, D, Weir, JM, Welti, R, Wenk, MR, Wheelock, CE, Yao, L, Yuan, M, Zhao, XH, and Zhou, S. "Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma." Journal of Lipid Research 58, no. 12 (December 2017): 2275-2288.  Full Text
    • Shwab, EK, Juvvadi, PR, Waitt, G, Soderblom, EJ, Moseley, MA, Nicely, NI, and Steinbach, WJ. "Phosphorylation of Aspergillus fumigatus PkaR impacts growth and cell wall integrity through novel mechanisms." Febs Letters 591, no. 22 (November 9, 2017): 3730-3744. (Letter)  Full Text
    • St John-Williams, L, Blach, C, Toledo, JB, Rotroff, DM, Kim, S, Klavins, K, Baillie, R, Han, X, Mahmoudiandehkordi, S, Jack, J, Massaro, TJ, Lucas, JE, Louie, G, Motsinger-Reif, AA, Risacher, SL, Alzheimer’s Disease Neuroimaging Initiative, , Alzheimer’s Disease Metabolomics Consortium, , Saykin, AJ, Kastenmüller, G, Arnold, M, Koal, T, Moseley, MA, Mangravite, LM, Peters, MA, Tenenbaum, JD, Thompson, JW, and Kaddurah-Daouk, R. "Targeted metabolomics and medication classification data from participants in the ADNI1 cohort." Scientific data 4 (October 17, 2017): 170140-.  Full Text
    • Banks, CJ, Rodriguez, NW, Gashler, KR, Pandya, RR, Mortenson, JB, Whited, MD, Soderblom, EJ, Thompson, JW, Moseley, MA, Reddi, AR, Tessem, JS, Torres, MP, Bikman, BT, and Andersen, JL. "Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-Mediated Inhibition of Mitochondrial Respiration." Molecular and Cellular Biology 37, no. 20 (October 2017).  Full Text
    • Toledo, JB, Arnold, M, Kastenmüller, G, Chang, R, Baillie, RA, Han, X, Thambisetty, M, Tenenbaum, JD, Suhre, K, Thompson, JW, John-Williams, LS, MahmoudianDehkordi, S, Rotroff, DM, Jack, JR, Motsinger-Reif, A, Risacher, SL, Blach, C, Lucas, JE, Massaro, T, Louie, G, Zhu, H, Dallmann, G, Klavins, K, Koal, T, Kim, S, Nho, K, Shen, L, Casanova, R, Varma, S, Legido-Quigley, C, Moseley, MA, Zhu, K, Henrion, MYR, van der Lee, SJ, Harms, AC, Demirkan, A, Hankemeier, T, van Duijn, CM, Trojanowski, JQ, Shaw, LM, Saykin, AJ, Weiner, MW, Doraiswamy, PM, Kaddurah-Daouk, R, and Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium, . "Metabolic network failures in Alzheimer's disease: A biochemical road map." Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association 13, no. 9 (September 2017): 965-984.  Full Text
    • Wang, H, Drake, SK, Yong, C, Gucek, M, Lyes, MA, Rosenberg, AZ, Soderblom, E, Arthur Moseley, M, Dekker, JP, and Suffredini, AF. "A Genoproteomic Approach to Detect Peptide Markers of Bacterial Respiratory Pathogens." Clinical chemistry 63, no. 8 (August 2017): 1398-1408.  Full Text
    • Brass, DM, Gwinn, WM, Valente, AM, Kelly, FL, Brinkley, CD, Nagler, AE, Moseley, MA, Morgan, DL, Palmer, SM, and Foster, MW. "The Diacetyl-Exposed Human Airway Epithelial Secretome: New Insights into Flavoring-Induced Airways Disease." American journal of respiratory cell and molecular biology 56, no. 6 (June 2017): 784-795.  Full Text
    • Tu, TM, Kolls, BJ, Soderblom, EJ, Cantillana, V, Ferrell, PD, Moseley, MA, Wang, H, Dawson, HN, and Laskowitz, DT. "Apolipoprotein E mimetic peptide, CN-105, improves outcomes in ischemic stroke." Annals of clinical and translational neurology 4, no. 4 (April 2017): 246-265.  Full Text
    • Vargas-Muñiz, JM, Renshaw, H, Waitt, G, Soderblom, EJ, Moseley, MA, Palmer, JM, Juvvadi, PR, Keller, NP, and Steinbach, WJ. "Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus." Biochemical and Biophysical Research Communications 485, no. 2 (April 2017): 221-226.  Full Text
    • Wang, L, Ko, ER, Gilchrist, JJ, Pittman, KJ, Rautanen, A, Pirinen, M, Thompson, JW, Dubois, LG, Langley, RJ, Jaslow, SL, Salinas, RE, Rouse, DC, Moseley, MA, Mwarumba, S, Njuguna, P, Mturi, N, Wellcome Trust Case Control Consortium 2, , Kenyan Bacteraemia Study Group, , Williams, TN, Scott, JAG, Hill, AVS, Woods, CW, Ginsburg, GS, Tsalik, EL, and Ko, DC. "Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis." Science Advances 3, no. 3 (March 8, 2017): e1602096-null.  Full Text  Open Access Copy
    • Burke, TW, Henao, R, Soderblom, E, Tsalik, EL, Thompson, JW, McClain, MT, Nichols, M, Nicholson, BP, Veldman, T, Lucas, JE, Moseley, MA, Turner, RB, Lambkin-Williams, R, Hero, AO, Woods, CW, and Ginsburg, GS. "Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection." Ebiomedicine 17 (March 2017): 172-181.  Full Text
    • Shwab, EK, Juvvadi, PR, Waitt, G, Soderblom, EJ, Moseley, MA, Nicely, NI, Asfaw, YG, and Steinbach, WJ. "A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus." Mbio 8, no. 1 (February 7, 2017).  Full Text
    • Alexander, GM, Huang, YZ, Soderblom, EJ, He, X-P, Moseley, MA, and McNamara, JO. "Vagal nerve stimulation modifies neuronal activity and the proteome of excitatory synapses of amygdala/piriform cortex." Journal of Neurochemistry 140, no. 4 (February 3, 2017): 629-644.  Full Text
    • Foster, MW, Gwinn, WM, Kelly, FL, Brass, DM, Valente, AM, Moseley, MA, Thompson, JW, Morgan, DL, and Palmer, SM. "Proteomic Analysis of Primary Human Airway Epithelial Cells Exposed to the Respiratory Toxicant Diacetyl." Journal of Proteome Research 16, no. 2 (February 2017): 538-549.  Full Text
    • Peterson, CT, Lucas, J, John-Williams, LS, Thompson, JW, Moseley, MA, Patel, S, Peterson, SN, Porter, V, Schadt, EE, Mills, PJ, Tanzi, RE, Doraiswamy, PM, and Chopra, D. "Corrigendum: Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI)." Scientific reports 6 (October 10, 2016): 34678-.  Full Text
    • Feger, BJ, Thompson, JW, Dubois, LG, Kommaddi, RP, Foster, MW, Mishra, R, Shenoy, SK, Shibata, Y, Kidane, YH, Moseley, MA, Carnell, LS, and Bowles, DE. "Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection." Scientific Reports 6 (September 27, 2016): 34091-null.  Full Text
    • Park, H-S, Chow, EWL, Fu, C, Soderblom, EJ, Moseley, MA, Heitman, J, and Cardenas, ME. "Calcineurin Targets Involved in Stress Survival and Fungal Virulence." Plos Pathogens 12, no. 9 (September 9, 2016): e1005873-null.  Full Text  Open Access Copy
    • Peterson, CT, Lucas, J, John-Williams, LS, Thompson, JW, Moseley, MA, Patel, S, Peterson, SN, Porter, V, Schadt, EE, Mills, PJ, Tanzi, RE, Doraiswamy, PM, and Chopra, D. "Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI)." Scientific Reports 6 (September 9, 2016): 32609-null.  Full Text
    • Quinones, QJ, Zhang, Z, Ma, Q, Smith, MP, Soderblom, E, Moseley, MA, Bain, J, Newgard, CB, Muehlbauer, MJ, Hirschey, M, Drew, KL, Barnes, BM, and Podgoreanu, MV. "Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats." Anesthesiology 124, no. 6 (June 2016): 1296-1310.  Full Text
    • Harrison, A, Dubois, LG, St John-Williams, L, Moseley, MA, Hardison, RL, Heimlich, DR, Stoddard, A, Kerschner, JE, Justice, SS, Thompson, JW, and Mason, KM. "Comprehensive Proteomic and Metabolomic Signatures of Nontypeable Haemophilus influenzae-Induced Acute Otitis Media Reveal Bacterial Aerobic Respiration in an Immunosuppressed Environment." Molecular & Cellular Proteomics : Mcp 15, no. 3 (March 2016): 1117-1138.  Full Text
    • Vargas-Muñiz, JM, Renshaw, H, Richards, AD, Waitt, G, Soderblom, EJ, Moseley, MA, Asfaw, Y, Juvvadi, PR, and Steinbach, WJ. "Dephosphorylation of the Core Septin, AspB, in a Protein Phosphatase 2A-Dependent Manner Impacts Its Localization and Function in the Fungal Pathogen Aspergillus fumigatus." Frontiers in Microbiology 7 (January 2016): 997-null.  Full Text
    • Barrientos, T, Laothamatas, I, Koves, TR, Soderblom, EJ, Bryan, M, Moseley, MA, Muoio, DM, and Andrews, NC. "Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle." Ebiomedicine 2, no. 11 (November 2015): 1705-1717.  Full Text
    • Figueiredo-Freitas, C, Dulce, RA, Foster, MW, Liang, J, Yamashita, AMS, Lima-Rosa, FL, Thompson, JW, Moseley, MA, Hare, JM, Nogueira, L, Sorenson, MM, and Pinto, JR. "S-Nitrosylation of Sarcomeric Proteins Depresses Myofilament Ca2+)Sensitivity in Intact Cardiomyocytes." Antioxidants & Redox Signaling 23, no. 13 (November 2015): 1017-1034.  Full Text
    • Vermulst, M, Denney, AS, Lang, MJ, Hung, C-W, Moore, S, Moseley, MA, Thompson, JW, Madden, V, Gauer, J, Wolfe, KJ, Summers, DW, Schleit, J, Sutphin, GL, Haroon, S, Holczbauer, A, Caine, J, Jorgenson, J, Cyr, D, Kaeberlein, M, Strathern, JN, Duncan, MC, and Erie, DA. "Corrigendum: Transcription errors induce proteotoxic stress and shorten cellular lifespan." Nature Communications 6 (October 14, 2015): 8738-8738.  Full Text
    • Foster, MW, Gerhardt, G, Robitaille, L, Plante, P-L, Boivin, G, Corbeil, J, and Moseley, MA. "Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures." Analytical chemistry 87, no. 20 (October 2015): 10247-10254.  Full Text
    • Vermulst, M, Denney, AS, Lang, MJ, Hung, C-W, Moore, S, Moseley, MA, Thompson, JW, Madden, V, Gauer, J, Wolfe, KJ, Summers, DW, Schleit, J, Sutphin, GL, Haroon, S, Holczbauer, A, Caine, J, Jorgenson, J, Cyr, D, Kaeberlein, M, Strathern, JN, Duncan, MC, and Erie, DA. "Transcription errors induce proteotoxic stress and shorten cellular lifespan." Nature Communications 6 (August 25, 2015): 8065-null.  Full Text
    • Bauernfeind, AL, Soderblom, EJ, Turner, ME, Moseley, MA, Ely, JJ, Hof, PR, Sherwood, CC, Wray, GA, and Babbitt, CC. "Evolutionary Divergence of Gene and Protein Expression in the Brains of Humans and Chimpanzees." Genome biology and evolution 7, no. 8 (August 2015): 2276-2288.  Full Text  Open Access Copy
    • Juvvadi, PR, Muñoz, A, Lamoth, F, Soderblom, EJ, Moseley, MA, Read, ND, and Steinbach, WJ. "Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus." Antimicrobial Agents and Chemotherapy 59, no. 8 (August 2015): 4946-4955.  Full Text
    • Lamoth, F, Juvvadi, PR, Soderblom, EJ, Moseley, MA, and Steinbach, WJ. "Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus." Antimicrobial Agents and Chemotherapy 59, no. 8 (August 2015): 4727-4733.  Full Text
    • Vargas-Muñiz, JM, Renshaw, H, Richards, AD, Lamoth, F, Soderblom, EJ, Moseley, MA, Juvvadi, PR, and Steinbach, WJ. "The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulence." Fungal Genetics and Biology : Fg & B 81 (August 2015): 41-51.  Full Text
    • Yung, C-M, Vereen, MK, Herbert, A, Davis, KM, Yang, J, Kantorowska, A, Ward, CS, Wernegreen, JJ, Johnson, ZI, and Hunt, DE. "Thermally adaptive tradeoffs in closely related marine bacterial strains." Environmental microbiology 17, no. 7 (July 2015): 2421-2429.  Full Text
    • Foster, MW, Morrison, LD, Todd, JL, Snyder, LD, Thompson, JW, Soderblom, EJ, Plonk, K, Weinhold, KJ, Townsend, R, Minnich, A, and Moseley, MA. "Quantitative proteomics of bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis." Journal of Proteome Research 14, no. 2 (February 2015): 1238-1249.  Full Text
    • Juvvadi, PR, Ma, Y, Richards, AD, Soderblom, EJ, Moseley, MA, Lamoth, F, and Steinbach, WJ. "Identification and mutational analyses of phosphorylation sites of the calcineurin-binding protein CbpA and the identification of domains required for calcineurin binding in Aspergillus fumigatus." Frontiers in Microbiology 6 (January 2015): 175-null.  Full Text
    • Paglia, G, Angel, P, Williams, JP, Richardson, K, Olivos, HJ, Thompson, JW, Menikarachchi, L, Lai, S, Walsh, C, Moseley, A, Plumb, RS, Grant, DF, Palsson, BO, Langridge, J, Geromanos, S, and Astarita, G. "Ion mobility-derived collision cross section as an additional measure for lipid fingerprinting and identification." Analytical Chemistry 87, no. 2 (January 2015): 1137-1144.  Full Text
    • Saka, HA, Thompson, JW, Chen, Y-S, Dubois, LG, Haas, JT, Moseley, A, and Valdivia, RH. "Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells." Plos One 10, no. 4 (January 2015): e0124630-null.  Full Text  Open Access Copy
    • Pfenning, AR, Hara, E, Whitney, O, Rivas, MV, Wang, R, Roulhac, PL, Howard, JT, Wirthlin, M, Lovell, PV, Ganapathy, G, Mouncastle, J, Moseley, MA, Thompson, JW, Soderblom, EJ, Iriki, A, Kato, M, Gilbert, MTP, Zhang, G, Bakken, T, Bongaarts, A, Bernard, A, Lein, E, Mello, CV, Hartemink, AJ, and Jarvis, ED. "Convergent transcriptional specializations in the brains of humans and song-learning birds." Science (New York, N.Y.) 346, no. 6215 (December 2014): 1256846-null.  Full Text  Open Access Copy
    • Mehta, K, Soderblom, EJ, Thompson, JW, Que, LG, Marshall, HE, Moseley, MA, and Foster, MW. "Targeted proteomics for unraveling the post-translational regulation of human nitric oxide synthase 2." Nitric Oxide 42C (November 15, 2014): 132-.  Full Text  Link to Item
    • Olson, AL, Tucker, AT, Bobay, BG, Soderblom, EJ, Moseley, MA, Thompson, RJ, and Cavanagh, J. "Structure and DNA-binding traits of the transition state regulator AbrB." Structure (London, England : 1993) 22, no. 11 (November 2014): 1650-1656.  Full Text
    • Jagannathan, S, Hsu, JC-C, Reid, DW, Chen, Q, Thompson, WJ, Moseley, AM, and Nicchitta, CV. "Multifunctional roles for the protein translocation machinery in RNA anchoring to the endoplasmic reticulum." The Journal of biological chemistry 289, no. 37 (September 2014): 25907-25924.  Full Text
    • Foster, MW, Thompson, JW, Ledford, JG, Dubois, LG, Hollingsworth, JW, Francisco, D, Tanyaratsrisakul, S, Voelker, DR, Kraft, M, Moseley, MA, and Foster, WM. "Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A." Journal of Proteome Research 13, no. 8 (August 2014): 3722-3732.  Full Text
    • Tucker, AT, Bobay, BG, Banse, AV, Olson, AL, Soderblom, EJ, Moseley, MA, Thompson, RJ, Varney, KM, Losick, R, and Cavanagh, J. "A DNA mimic: the structure and mechanism of action for the anti-repressor protein AbbA." Journal of Molecular Biology 426, no. 9 (May 2014): 1911-1924.  Full Text
    • Tucker, AT, Bobay, BG, Banse, AV, Olson, AL, Soderblom, EJ, Moseley, MA, Thompson, RJ, Varney, KM, Losick, R, and Cavanagh, J. "A DNA mimic: The structure and mechanism of action for the anti-repressor protein AbbA." Journal of Molecular Biology 426, no. 9 (May 1, 2014): 1911-1924.  Full Text
    • Paglia, G, Williams, JP, Menikarachchi, L, Thompson, JW, Tyldesley-Worster, R, Halldórsson, S, Rolfsson, O, Moseley, A, Grant, D, Langridge, J, Palsson, BO, and Astarita, G. "Ion mobility derived collision cross sections to support metabolomics applications." Analytical Chemistry 86, no. 8 (April 2014): 3985-3993.  Full Text
    • Yang, W, Sheng, H, Thompson, JW, Zhao, S, Wang, L, Miao, P, Liu, X, Moseley, MA, and Paschen, W. "Small ubiquitin-like modifier 3-modified proteome regulated by brain ischemia in novel small ubiquitin-like modifier transgenic mice: putative protective proteins/pathways." Stroke 45, no. 4 (April 2014): 1115-1122.  Full Text
    • Iwabuchi, M, Sheng, H, Thompson, J, Wang, L, Dubois, LG, Gooden, D, Moseley, M, Paschen, W, and Yang, W. "Characterization of the ubiquitin-modified proteome regulated by transient forebrain ischemia." Journal of Cerebral Blood Flow and Metabolism 34, no. 3 (March 1, 2014): 425-432.  Full Text
    • Iwabuchi, M, Sheng, H, Thompson, JW, Wang, L, Dubois, LG, Gooden, D, Moseley, M, Paschen, W, and Yang, W. "Characterization of the ubiquitin-modified proteome regulated by transient forebrain ischemia." Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism 34, no. 3 (March 2014): 425-432.  Full Text
    • Lamoth, F, Juvvadi, PR, Soderblom, EJ, Moseley, MA, Asfaw, YG, and Steinbach, WJ. "Identification of a key lysine residue in heat shock protein 90 required for azole and echinocandin resistance in Aspergillus fumigatus." Antimicrobial Agents and Chemotherapy 58, no. 4 (January 6, 2014): 1889-1896.  Full Text
    • Little, D, Thompson, JW, Dubois, LG, Ruch, DS, Moseley, MA, and Guilak, F. "Proteomic differences between male and female anterior cruciate ligament and patellar tendon." PloS one 9, no. 5 (January 2014): e96526-.  Full Text
    • Schechter, MA, Hsieh, MKH, Njoroge, LW, Thompson, JW, Soderblom, EJ, Feger, BJ, Troupes, CD, Hershberger, KA, Ilkayeva, OR, Nagel, WL, Landinez, GP, Shah, KM, Burns, VA, Santacruz, L, Hirschey, MD, Foster, MW, Milano, CA, Moseley, MA, Piacentino, V, and Bowles, DE. "Phosphoproteomic profiling of human myocardial tissues distinguishes ischemic from non-ischemic end stage heart failure." PLoS ONE 9, no. 8 (January 2014): e104157-.  Full Text  Open Access Copy
    • Yang, W, Sheng, H, Thompson, JW, Zhao, S, Wang, L, Miao, P, Liu, X, Moseley, MA, and Paschen, W. "Small ubiquitin-like modifier 3-modified proteome regulated by brain ischemia in novel small ubiquitin-like modifier transgenic mice: Putative protective proteins/pathways." Stroke 45, no. 4 (January 1, 2014): 1115-1122.  Full Text
    • Benjamin, AM, Thompson, JW, Soderblom, EJ, Geromanos, SJ, Henao, R, Kraus, VB, Moseley, MA, and Lucas, JE. "A flexible statistical model for alignment of label-free proteomics data--incorporating ion mobility and product ion information." BMC bioinformatics 14 (December 16, 2013): 364-.  Full Text  Open Access Copy
    • Fouda, GG, Jaeger, FH, Amos, JD, Ho, C, Kunz, EL, Anasti, K, Stamper, LW, Liebl, BE, Barbas, KH, Ohashi, T, Moseley, MA, Liao, H-X, Erickson, HP, Alam, SM, and Permar, SR. "Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk." Proc Natl Acad Sci U S A 110, no. 45 (November 5, 2013): 18220-18225.  Full Text  Open Access Copy  Link to Item
    • Foster, MW, Thompson, JW, Forrester, MT, Sha, Y, McMahon, TJ, Bowles, DE, Moseley, MA, and Marshall, HE. "Proteomic analysis of the NOS2 interactome in human airway epithelial cells." Nitric Oxide 34 (November 2013): 37-46.  Full Text
    • Foster, MW, Thompson, JW, Forrester, MT, Sha, Y, McMahon, TJ, Bowles, DE, Moseley, MA, and Marshall, HE. "Proteomic analysis of the NOS2 interactome in human airway epithelial cells." Nitric oxide : biology and chemistry 34 (November 2013): 37-46.  Full Text
    • Hoos, MD, Richardson, BM, Foster, MW, Everhart, A, Thompson, JW, Moseley, MA, and Colton, CA. "Longitudinal study of differential protein expression in an Alzheimer's mouse model lacking inducible nitric oxide synthase." Journal of Proteome Research 12, no. 10 (October 2013): 4462-4477.  Full Text
    • Thompson, JW, Forrester, MT, Moseley, MA, and Foster, MW. "Solid-phase capture for the detection and relative quantification of S-nitrosoproteins by mass spectrometry." Methods (San Diego, Calif.) 62, no. 2 (August 2013): 130-137. (Review)  Full Text
    • Langley, RJ, Tsalik, EL, van Velkinburgh, JC, Glickman, SW, Rice, BJ, Wang, C, Chen, B, Carin, L, Suarez, A, Mohney, RP, Freeman, DH, Wang, M, You, J, Wulff, J, Thompson, JW, Moseley, MA, Reisinger, S, Edmonds, BT, Grinnell, B, Nelson, DR, Dinwiddie, DL, Miller, NA, Saunders, CJ, Soden, SS, Rogers, AJ, Gazourian, L, Fredenburgh, LE, Massaro, AF, Baron, RM, Choi, AMK, Corey, GR, Ginsburg, GS, Cairns, CB, Otero, RM, Fowler, VG, Rivers, EP, Woods, CW, and Kingsmore, SF. "An integrated clinico-metabolomic model improves prediction of death in sepsis." Sci Transl Med 5, no. 195 (July 24, 2013): 195ra95-null.  Full Text  Link to Item
    • Foster, MW, Thompson, JW, Que, LG, Yang, IV, Schwartz, DA, Moseley, MA, and Marshall, HE. "Proteomic analysis of human bronchoalveolar lavage fluid after subsgemental exposure." J Proteome Res 12, no. 5 (May 3, 2013): 2194-2205.  Full Text  Link to Item
    • Richardson, BM, Soderblom, EJ, Thompson, JW, and Moseley, MA. "Automated, reproducible, titania-based phosphopeptide enrichment strategy for label-free quantitative phosphoproteomics." Journal of biomolecular techniques : JBT 24, no. 1 (April 2013): 8-16.  Full Text
    • Kummarapurugu, AB, Fischer, BM, Zheng, S, Milne, GL, Ghio, AJ, Potts-Kant, EN, Foster, WM, Soderblom, EJ, Dubois, LG, Moseley, MA, Thompson, JW, and Voynow, JA. "NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation." J Biol Chem 288, no. 7 (February 15, 2013): 4681-4691.  Full Text  Link to Item
    • Fan, Y, Thompson, JW, Dubois, LG, Moseley, MA, and Wernegreen, JJ. "Proteomic analysis of an unculturable bacterial endosymbiont (Blochmannia) reveals high abundance of chaperonins and biosynthetic enzymes." Journal of Proteome Research 12, no. 2 (February 2013): 704-718.  Full Text
    • Juvvadi, PR, Belina, D, Soderblom, EJ, Moseley, MA, and Steinbach, WJ. "Filamentous fungal-specific septin AspE is phosphorylated in vivo and interacts with actin, tubulin and other septins in the human pathogen Aspergillus fumigatus." Biochemical and Biophysical Research Communications 431, no. 3 (February 2013): 547-553.  Full Text
    • Soderblom, EJ, Thompson, JW, Schwartz, EA, Chiou, E, Dubois, LG, Moseley, MA, and Zennadi, R. "Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation." Clinical proteomics 10, no. 1 (January 3, 2013): 1-.  Full Text  Open Access Copy
    • Foster, MW, Thompson, JW, Que, LG, Yang, IV, Schwartz, DA, Moseley, MA, and Marshall, HE. "Proteomic Analysis Of Human Bronchoalveolar Lavage Fluid After Subsegmental Challenge." AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 187 (2013).  Link to Item
    • Juvvadi, PR, Gehrke, C, Fortwendel, JR, Lamoth, F, Soderblom, EJ, Cook, EC, Hast, MA, Asfaw, YG, Moseley, MA, Creamer, TP, and Steinbach, WJ. "Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus." Plos Pathogens 9, no. 8 (January 2013): e1003564-null.  Full Text
    • Ralston-Hooper, KJ, Turner, ME, Soderblom, EJ, Villeneuve, D, Ankley, GT, Moseley, MA, Hoke, RA, and Ferguson, PL. "Application of a label-free, gel-free quantitative proteomics method for ecotoxicological studies of small fish species." Environmental Science & Technology 47, no. 2 (January 2013): 1091-1100.  Full Text
    • Thompson, JW, Forrester, MT, Moseley, MA, and Foster, MW. "Solid-phase capture for the detection and relative quantification of S-nitrosoproteins by mass spectrometry." Methods 62, no. 2 (2013): 130-137.  Full Text
    • Chan, MY, Lin, M, Lucas, J, Moseley, A, Thompson, JW, Cyr, D, Ueda, H, Kajikawa, M, Ortel, TL, and Becker, RC. "Plasma proteomics of patients with non-valvular atrial fibrillation on chronic anti-coagulation with warfarin or a direct factor Xa inhibitor." Thromb Haemost 108, no. 6 (December 2012): 1180-1191.  Full Text  Link to Item
    • Thompson, JW, Zhang, H, Smith, P, Hillman, S, Moseley, MA, and Millington, DS. "Extraction and analysis of carnitine and acylcarnitines by electrospray ionization tandem mass spectrometry directly from dried blood and plasma spots using a novel autosampler." Rapid Communications in Mass Spectrometry : Rcm 26, no. 21 (November 2012): 2548-2554.  Full Text
    • Thalassinos, K, Vissers, JPC, Tenzer, S, Levin, Y, Thompson, JW, Daniel, D, Mann, D, DeLong, MR, Moseley, MA, America, AH, Ottens, AK, Cavey, GS, Efstathiou, G, Scrivens, JH, Langridge, JI, and Geromanos, SJ. "Design and application of a data-independent precursor and product ion repository." Journal of the American Society for Mass Spectrometry 23, no. 10 (October 2012): 1808-1820.  Full Text
    • Schumacher, MA, Min, J, Link, TM, Guan, Z, Xu, W, Ahn, Y-H, Soderblom, EJ, Kurie, JM, Evdokimov, A, Moseley, MA, Lewis, K, and Brennan, RG. "Role of unusual P loop ejection and autophosphorylation in HipA-mediated persistence and multidrug tolerance." Cell Reports 2, no. 3 (September 20, 2012): 518-525.  Full Text
    • Gu, JJ, Lavau, CP, Pugacheva, E, Soderblom, EJ, Moseley, MA, and Pendergast, AM. "Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1." Science Signaling 5, no. 233 (July 17, 2012): ra51-null.  Full Text
    • Lucas, JE, Thompson, JW, Dubois, LG, McCarthy, J, Tillmann, H, Thompson, A, Shire, N, Hendrickson, R, Dieguez, F, Goldman, P, Schwarz, K, Patel, K, McHutchison, J, and Moseley, MA. "Metaprotein expression modeling for label-free quantitative proteomics. (Published online)" BMC Bioinformatics 13 (May 4, 2012): 74-.  Full Text  Link to Item
    • Petricka, JJ, Schauer, MA, Megraw, M, Breakfield, NW, Thompson, JW, Georgiev, S, Soderblom, EJ, Ohler, U, Moseley, MA, Grossniklaus, U, and Benfey, PN. "The protein expression landscape of the Arabidopsis root." Proc Natl Acad Sci U S A 109, no. 18 (May 1, 2012): 6811-6818.  Full Text  Link to Item
    • Qian, J, Chen, F, Kovalenkov, Y, Pandey, D, Moseley, MA, Foster, MW, Black, SM, Venema, RC, Stepp, DW, and Fulton, DJR. "Nitric oxide reduces NADPH oxidase 5 (Nox5) activity by reversible S-nitrosylation." Free Radic Biol Med 52, no. 9 (May 1, 2012): 1806-1819.  Full Text  Link to Item
    • Foster, MW, Yang, Z, Gooden, DM, Thompson, JW, Ball, CH, Turner, ME, Hou, Y, Pi, J, Moseley, MA, and Que, LG. "Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition." J Proteome Res 11, no. 4 (April 6, 2012): 2480-2491.  Full Text  Link to Item
    • Yang, W, Thompson, JW, Wang, Z, Wang, L, Sheng, H, Foster, MW, Moseley, MA, and Paschen, W. "Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics." Journal of Proteome Research 11, no. 2 (February 2012): 1108-1117.  Full Text
    • Zennadi, R, Whalen, EJ, Soderblom, EJ, Alexander, SC, Thompson, JW, Dubois, LG, Moseley, MA, and Telen, MJ. "Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium." Blood 119, no. 5 (February 2012): 1217-1227.  Full Text
    • Henao, R, Thompson, JW, Moseley, MA, Ginsburg, GS, Carin, L, and Lucas, JE. "Hierarchical factor modeling of proteomics data." 2012 IEEE 2nd International Conference on Computational Advances in Bio and Medical Sciences, ICCABS 2012 (2012).  Full Text
    • Okada, H, Uezu, A, Soderblom, EJ, Moseley, MA, Gertler, FB, and Soderling, SH. "Peptide array X-linking (PAX): a new peptide-protein identification approach." PLoS One 7, no. 5 (2012): e37035-.  Full Text  Link to Item
    • Saka, HA, Thompson, JW, Chen, Y-S, Kumar, Y, Dubois, LG, Moseley, MA, and Valdivia, RH. "Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms." Molecular Microbiology 82, no. 5 (December 2011): 1185-1203.  Full Text
    • Okada, H, Uezu, A, Mason, FM, Soderblom, EJ, Moseley, MA, and Soderling, SH. "SH3 domain-based phototrapping in living cells reveals Rho family GAP signaling complexes. (Published online)" Sci Signal 4, no. 201 (November 29, 2011): rs13-.  Full Text  Link to Item
    • Andersen, JL, Thompson, JW, Lindblom, KR, Johnson, ES, Yang, C-S, Lilley, LR, Freel, CD, Moseley, MA, and Kornbluth, S. "A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2." Molecular cell 43, no. 5 (September 2011): 834-842.  Full Text
    • Melvin, JA, Murphy, CF, Dubois, LG, Thompson, JW, Moseley, MA, and McCafferty, DG. "Staphylococcus aureus sortase A contributes to the Trojan horse mechanism of immune defense evasion with its intrinsic resistance to Cys184 oxidation." Biochemistry 50, no. 35 (September 2011): 7591-7599.  Full Text
    • Patel, K, Lucas, JE, Thompson, JW, Dubois, LG, Tillmann, HL, Thompson, AJ, Uzarski, D, Califf, RM, Moseley, MA, Ginsburg, GS, McHutchison, JG, McCarthy, JJ, and MURDOCK Horizon 1 Study Team, . "High predictive accuracy of an unbiased proteomic profile for sustained virologic response in chronic hepatitis C patients." Hepatology (Baltimore, Md.) 53, no. 6 (June 2011): 1809-1818.  Full Text
    • Soderblom, EJ, Philipp, M, Thompson, JW, Caron, MG, and Moseley, MA. "Quantitative label-free phosphoproteomics strategy for multifaceted experimental designs." Anal Chem 83, no. 10 (May 15, 2011): 3758-3764.  Full Text  Link to Item
    • Andersen, JL, Thompson, JW, Buchakjian, MR, Moseley, MA, and Kornbluth, S. "Abstract 4697: Metabolic regulation of caspase-2." Cancer Research 71, no. 8 Supplement (April 15, 2011): 4697-4697.  Full Text
    • Reidel, B, Thompson, JW, Farsiu, S, Moseley, MA, Skiba, NP, and Arshavsky, VY. "Proteomic profiling of a layered tissue reveals unique glycolytic specializations of photoreceptor cells." Molecular & Cellular Proteomics : Mcp 10, no. 3 (March 2011): M110.002469-null.  Full Text
    • Forrester, MT, Hess, DT, Thompson, JW, Hultman, R, Moseley, MA, Stamler, JS, and Casey, PJ. "Site-specific analysis of protein S-acylation by resin-assisted capture." Journal of Lipid Research 52, no. 2 (February 2011): 393-398.  Full Text
    • Roulhac, PL, Ward, JM, Thompson, JW, Soderblom, EJ, Silva, M, Moseley, MA, and Jarvis, ED. "Microproteomics: Quantitative Proteomic Profiling of Small Numbers of Laser-Captured Cells." Cold Spring Harbor Protocols 2011, no. 2 (February 1, 2011): pdb.prot5573-pdb.prot5573.  Full Text  Open Access Copy
    • Roulhac, PL, Ward, JM, Thompson, JW, Soderblom, EJ, Silva, M, Moseley, MA, and Jarvis, ED. "Microproteomics: quantitative proteomic profiling of small numbers of laser-captured cells. (Published online)" Cold Spring Harb Protoc 2011, no. 2 (February 1, 2011): pdb.prot5573-.  Open Access Copy  Link to Item
    • Cyr, DD, Lucas, JE, Thompson, JW, Patel, K, Clark, PJ, Thompson, A, Tillmann, HL, McHutchison, JG, Moseley, MA, and McCarthy, JJ. "Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C." PLoS One 6, no. 7 (2011): e21854-.  Full Text  Link to Item
    • Kozubowski, L, Thompson, JW, Cardenas, ME, Moseley, MA, and Heitman, J. "Association of calcineurin with the COPI protein Sec28 and the COPII protein Sec13 revealed by quantitative proteomics." PLoS One 6, no. 10 (2011): e25280-.  Full Text  Link to Item
    • Okada, H, Uezu, A, Mason, FM, Soderblom, EJ, 3rd, MAM, and Soderling, SH. "SH3 domain-based phototrapping in living cells reveals Rho family GAP signaling complexes." Science signaling 4, no. 201 (2011): rs13-.  Full Text
    • Lee, A, Toffaletti, DL, Tenor, J, Soderblom, EJ, Thompson, JW, Moseley, MA, Price, M, and Perfect, JR. "Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis." Infection and Immunity 78, no. 10 (October 2010): 4213-4225.  Full Text
    • Benhar, M, Thompson, JW, Moseley, MA, and Stamler, JS. "Identification of S-nitrosylated targets of thioredoxin using a quantitative proteomic approach." Biochemistry 49, no. 32 (August 2010): 6963-6969.  Full Text  Open Access Copy
    • Morris, DP, Roush, ED, Thompson, JW, Moseley, MA, Murphy, JW, and McMurry, JL. "Kinetic characterization of Salmonella FliK-FlhB interactions demonstrates complexity of the Type III secretion substrate-specificity switch." Biochemistry 49, no. 30 (August 2010): 6386-6393.  Full Text  Open Access Copy
    • West, GM, Thompson, JW, Soderblom, EJ, Dubois, LG, Dearmond, PD, Moseley, MA, and Fitzgerald, MC. "Mass spectrometry-based thermal shift assay for protein-ligand binding analysis." Anal Chem 82, no. 13 (July 1, 2010): 5573-5581.  Full Text  Open Access Copy  Link to Item
    • Xia, W, Bacus, S, Husain, I, Liu, L, Zhao, S, Liu, Z, Moseley, MA, Thompson, JW, Chen, FL, Koch, KM, and Spector, NL. "Resistance to ErbB2 tyrosine kinase inhibitors in breast cancer is mediated by calcium-dependent activation of RelA." Molecular cancer therapeutics 9, no. 2 (February 2, 2010): 292-299.  Full Text
    • Andersen, JL, Johnson, CE, Freel, CD, Parrish, AB, Day, JL, Buchakjian, MR, Nutt, LK, Thompson, JW, Moseley, MA, and Kornbluth, S. "Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2." The Embo Journal 28, no. 20 (October 2009): 3216-3227.  Full Text
    • Forrester, MT, Thompson, JW, Foster, MW, Nogueira, L, Moseley, MA, and Stamler, JS. "Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture." Nature Biotechnology 27, no. 6 (June 2009): 557-559.  Full Text
    • Li, J, Martin, A, Cox, AD, Moxon, ER, Richards, JC, and Thibault, P. "Mapping bacterial glycolipid complexity using capillary electrophoresis and electrospray mass spectrometry." Methods in Enzymology 405 (2006): 369-397.  Full Text
    • Bodnar, WM, Blackburn, RK, Krise, JM, and Moseley, MA. "Exploiting the complementary nature of LC/MALDI/MS/MS and LC/ESI/MS/MS for increased proteome coverage." Journal of the American Society for Mass Spectrometry 14, no. 9 (2003): 971-979.  Full Text
    • Bodnar, WM, Bell, DJ, Blackburn, RK, Davis, RG, Flynn, HR, Forrest, RM, Krise, JM, Lee, MJ, Moseley, MA, Moyer, MB, and al, E. "Evaluation of automated in-gel digestion coupled with MALDI/MS and MALDI/MS/MS for protein identification." Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (2002): 171-172.
    • Ostrowski, LE, Blackburn, K, Radde, KM, Moyer, MB, Schlatzer, DM, Moseley, A, and Boucher, RC. "A proteomic analysis of human cilia: identification of novel components." Molecular & cellular proteomics : MCP 1, no. 6 (2002): 451-465.
    • Schlatzer, D, Armstrong, J, Blackburn, K, Burkhart, W, Davis, R, Iving, A, Jing, J, Kadwell, S, Krise, J, Moyer, M, and al, E. "LC/LC/MS/MS analysis of a complex proteome and protein classification by gene onology." Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (2002): 189-190.
    • Vissers, JPC, Blackburn, RK, and Moseley, MA. "A novel interface for variable flow nanoscale LC/MS/MS for improved proteome coverage." Journal of the American Society for Mass Spectrometry 13, no. 7 (2002): 760-771.  Full Text
    • Koc, EC, Burkhart, W, Blackburn, K, Koc, H, Moseley, A, and Spremulli, LL. "Identification of four proteins from the small subunit of the mammalian mitochondrial ribosome using a proteomics approach." Protein Science 10, no. 3 (2001): 471-481.  Full Text
    • Koc, EC, Burkhart, W, Blackburn, K, Moseley, A, and Spremulli, LL. "The small subunit of the mammalian mitochondrial ribosome: Identification of the full complement of ribosomal proteins present." Journal of Biological Chemistry 276, no. 22 (2001): 19363-19374.  Full Text
    • Koc, EC, Burkhart, W, Blackburn, K, Moyer, MB, Schlatzer, DM, Moseley, A, and Spremulli, LL. "The large subunit of the mammalian mitochondrial ribosome: Analysis of the complement of ribosomal proteins present." Journal of Biological Chemistry 276, no. 47 (2001): 43958-43969.  Full Text
    • Koc, EC, Ranasinghe, A, Burkhart, W, Blackburn, K, Koc, H, Moseley, A, and Spremulli, LL. "A new face on apoptosis: Death-associated protein 3 and PDCD9 are mitochondrial ribosomal proteins." FEBS Letters 492, no. 1-2 (2001): 166-170.  Full Text
    • Moseley, MA. "Current trends in differential expression proteomics: isotopically coded tags." Trends in Biotechnology 19, no. 10 Suppl (2001): S10-S16.
    • Tolley, L, Jorgenson, JW, and Moseley, MA. "Very high pressure gradient LC/MS/MS." Analytical Chemistry 73, no. 13 (2001): 2985-2991.  Full Text
    • Smith, JJ, Evans, EK, Murakami, M, Moyer, MB, Moseley, MA, Vande Woude, G, and Kornbluth, S. "Wee1-regulated apoptosis mediated by the crk adaptor protein in Xenopus egg extracts." J Cell Biol 151, no. 7 (December 25, 2000): 1391-1400.  Open Access Copy  Link to Item
    • Koc, EC, Burkhart, W, Blackburn, K, Moseley, A, Koc, H, and Spremulli, LL. "A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins." Journal of Biological Chemistry 275, no. 42 (2000): 32585-32591.
    • Li, J, Thibault, P, Martin, A, Richards, JC, Wakarchuk, WW, and Wilp, WVD. "Development of an on-line preconcentration method for the analysis of pathogenic lipopolysaccharides using capillary electrophoresis-electrospray mass spectrometryApplication to small colony isolates." Journal of Chromatography A 817, no. 1-2 (1998): 325-336.  Full Text
    • Opiteck, GJ, Jorgenson, JW, III, MAM, and Anderegg, RJ. "Two-Dimensional Microcolumn HPLC Coupled to a Single-Quadrupole Mass Spectrometer for the Elucidation of Sequence Tags and Peptide Mapping." Journal of Microcolumn Separations 10, no. 4 (1998): 365-375.
    • Opiteck, GJ, Ramirez, SM, Jorgenson, JW, and III, MAM. "Comprehensive two-dimensional high-performance liquid chromatography for the isolation of overexpressed proteins and proteome mapping." Analytical Biochemistry 258, no. 2 (1998): 349-361.  Full Text
    • Chen, C, Jeffery, D, Jorgenson, JW, Moseley, MA, and Pollack, GM. "Sensitive analysis of [D-Pen^2,5]enkephalin in rat serum by capillary electrophoresis and laser-induced fluorescence detection." Journal of Chromatography B: Biomedical Applications 697, no. 1-2 (1997): 149-162.  Full Text
    • MacNair, JE, Opiteck, GJ, Jorgenson, JW, and III, MAM. "Research methods and applications rapid separation and characterization of protein and peptide mixtures using 1.5 μm diameter non-porous silica in packed capillary liquid chromatography/mass spectrometry." Rapid Communications in Mass Spectrometry 11, no. 12 (1997): 1279-1285.  Full Text
    • MacNair, JE, Opiteck, GJ, Jorgenson, JW, and Moseley, MA. "Rapid separation and characterization of protein and peptide mixtures using 1.5 microns diameter non-porous silica in packed capillary liquid chromatography/mass spectrometry." Rapid Communications in Mass Spectrometry : Rcm 11, no. 12 (January 1997): 1279-1285.  Full Text
    • Gan, LS, Moseley, MA, Khosla, B, Augustijns, PF, Bradshaw, TP, Hendren, RW, and Thakker, DR. "CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells." Drug metabolism and disposition: the biological fate of chemicals 24, no. 3 (March 1996): 344-349.
    • Tomer, KB, Moseley, MA, Deterding, LJ, and Parker, CE. "Capillary liquid chromatography/ mass spectrometry." Mass Spectrometry Reviews 13, no. 5-6 (1994): 431-457.
    • Moseley, MA, and Unger, SE. "Packed capillary liquid chromatography/electrospray ionization/mass spectrometry in the pharmaceutical sciences: Characterization of protein mixtures." Journal of Microcolumn Separations 4, no. 5 (September 1992): 393-398.  Full Text
    • Moseley, MA, Jorgenson, JW, Shabanowitz, J, Hunt, DF, and Tomer, KB. "Optimization of capillary zone electrophoresis/electrospray ionization parameters for the mass spectrometry and tandem mass spectrometry analysis of peptides." Journal of the American Society for Mass Spectrometry 3, no. 4 (1992): 289-300.  Full Text
    • Deterding, LJ, Moseley, MA, Tomer, KB, and Jorgenson, JW. "Nanoscale separations combined with tandem mass spectrometry." Journal of Chromatography 554, no. 1-2 (1991): 73-82.  Full Text
    • Deterding, LJ, Parker, CE, Perkins, JR, Moseley, MA, Jorgenson, JW, and Tomer, KB. "Nanoscale separations. Capillary liquid chromatography-mass spectrometry and capillary zone electrophoresis-mass spectrometry for the determination of peptides and proteins." Journal of Chromatography A 554, no. 1-2 (1991): 329-338.  Full Text
    • Moseley, MA, Deterding, LJ, Tomer, KB, and Jorgenson, JW. "Nanoscale packed-capillary liquid chromatography coupled with mass spectrometry using a coaxial continuous-flow fast atom bombardment interface." Analytical Chemistry 63, no. 14 (1991): 1467-1473.
    • Moseley, MA, Deterding, LJ, Tomer, KB, and Jorgenson, JW. "Determination of bioactive peptides using capillary zone electrophoresis/mass spectrometry." Analytical Chemistry 63, no. 2 (1991): 109-114.
    • Moseley, MA, Deterding, LJ, Tomer, KB, and Jorgenson, JW. "Capillary zone electrophoresis-mass spectrometry using a coaxial continuous-flow fast atom bombardment interface." Journal of Chromatography 516, no. 1 (1990): 167-173.  Full Text
    • Pleasance, S, Thibault, P, Moseley, MA, Deterding, LJ, Tomer, KB, and Jorgenson, JW. "Continuous flow fast atom bombardment with packed microcolumns: A comparison of precolumn versus coaxial matrix delivery." Journal of the American Society for Mass Spectrometry 1, no. 4 (1990): 312-319.  Full Text
    • Deterding, LJ, Moseley, MA, Tomer, KB, and Jorgenson, JW. "Coaxial continuous flow fast atom bombardment in conjunction with tandem mass spectrometry for the analysis of biomolecules." Analytical Chemistry 61, no. 22 (1989): 2504-2511.
    • Moseley, MA, Deterding, LJ, Tomer, KB, and Jorgenson, JW. "Capillary-zone electrophoresis/fast-atom bombardment mass spectrometry: design of an on-line coaxial continuous-flow interface." Rapid communications in mass spectrometry : RCM 3, no. 3 (1989): 87-93.
    • Moseley, MA, Deterding, LJ, Tomer, KB, and Jorgenson, JW. "Coupling of capillary zone electrophoresis and capillary liquid chromatography with coaxial continuous-flow fast atom bombardment tandem sectro mass spectrometry." Journal of Chromatography A 480, no. C (1989): 197-209.
    • Moseley, MA, Deterding, LJ, Wit, JSMD, Tomer, KB, Kennedy, RT, Bragg, N, and Jorgenson, JW. "Optimization of a coaxial continuous flow fast atom bombardment interface between capillary liquid chromatography and magnetic sector mass spectrometry for the analysis of biomolecules." Analytical Chemistry 61, no. 14 (1989): 1577-1584.
    • de Wit, JSM, Deterding, LJ, Moseley, MA, Tomer, KB, Jorgenson, JW, and Caprioli, RM. "Design of a coaxial continuous flow fast atom bombardment probe." Rapid Communications in Mass Spectrometry 2, no. 5 (May 1988): 100-104.  Full Text
    • Raymer, JH, Moseley, MA, Pellizzari, ED, and Velez, GR. "Capillary supercritical fluid chromatography coupled with matrix isolation fourier transform infrared spectroscopy (SFC-MI-FTIR)." Journal of High Resolution Chromatography 11, no. 2 (February 1988): 209-211.  Full Text
    • Pellizzari, ED, Moseley, MA, and Cooper, SD. "Recent advances in the analysis of polychlorinated biphenyls in environmental and biological media." Journal of chromatography 334, no. 3 (November 1985): 277-314. (Review)  Full Text
    • Gurka, DF, Umaña, M, Pellizzari, ED, Moseley, A, and De Haseth, JA. "The Measurement of On-The-Fly Fourier Transform Infrared Reference Spectra of Environmentally Important Compounds." Applied Spectroscopy 39, no. 2 (March 1985): 297-303.  Full Text
    • Cooper, SD, Moseley, MA, and Pellizzari, ED. "Surrogate standards for the determination of individual polychlorinated biphenyls using high-resolution gas chromatography with electron capture detection." Analytical Chemistry 57, no. 13 (1985): 2469-2473.  Full Text
    • Pellizzari, ED, Moseley, MA, and Cooper, SD. "Recent advances in the analysis of polychlorinated biphenyls in environmental and biological media." Journal of Chromatography 334, no. 3 (1985): 277-314.
    • Moseley, MA, Pellizzari, ED, and Williams, LR. "EVALUATION OF SIMCA PATTERN RECOGNITION FOR USE WITH POLYCHLORINATED BIPHENYL DATA SETS." National Meeting - American Chemical Society, Division of Environmental Chemistry 24, no. 2 (1984): 63-64.
    • Moseley, MA, and Pellizzari, ED. "Polysiloxane deactivated fused silica capillaries containing immobilized stationary phases." Journal of High Resolution Chromatography 5, no. 9 (September 1982): 472-475.  Full Text
    • Hines, JW, Erickson, MD, Newton, DL, Moseley, MA, Retzlaff, LM, and Pellizzari, ED. "Simple fabrication of a “Grob” injector." Journal of High Resolution Chromatography 5, no. 1 (January 1982): 52-53.  Full Text
    • MOSELEY, MA, and PELLIZZARI, ED. "POLYSILOXANE DEACTIVATED FUSED SILICA CAPILLARIES CONTAINING IMMOBILIZED STATIONARY PHASES." HRC & CC J HIGH RESOLUT CHROMATOGR CHROMATOGR COMMUN V 5, no. N 9 (1982): 472-475.
    • Moseley, MA, and Pellizzari, ED. "DEVELOPMENT AND EVALUATION OF WALL COATED OPEN-TUBULAR COLUMNS FOR GC ANALYSIS OF INDIVIDUAL POLYCHLORINATED BIPHENYL ISOMERS." HRC & CC. Journal of high resolution chromatography & chromatography communications 5, no. 8 (1982): 404-412.
    • Wertz, DW, and Moseley, MA. "Vibrational study of the metal-olefin bond in 1,5-cyclooctadiene complexes of rhodium(I), palladium(II), and platinum(II)." Inorganic Chemistry 19, no. 3 (1980): 705-708.
    • Wertz, DW, and Moseley, MA. "A vibrational study of the metal-olefin bond in norbornadiene complexes of Rh(I), Pd(II) and Pt(II)." Spectrochimica Acta Part A: Molecular Spectroscopy 36, no. 5 (1980): 467-472.
    • Henao, R, Thompson, JW, Moseley, MA, Ginsburg, GS, Carin, L, and Lucas, JE. "Latent protein trees." Annals of Applied Statistics 7, no. 2: 691-713.  Full Text  Open Access Copy  Link to Item

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