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Ashutosh Chilkoti

Alan L. Kaganov Distinguished Professor of Biomedical Engineering
Biomedical Engineering
Box 90281, Durham, NC 27708-0281
3381 CIEMAS, Durham, NC 27708

Scholarly Works - Book sections


Surface Patterning

Book section · January 1, 2020 Surface patterning becomes an important tool in biomedical research and applications, as it enables systematic investigation of cell-biomaterial interaction as well as rapid, high-throughput tests for disease diagnosis and drug screening. Recent advances i ... Full text Cite

Enzymatic synthesis and modification of high molecular weight DNA using terminal deoxynucleotidyl transferase.

Book section · January 2019 The recognition that nucleic acids can be used as polymeric materials led to the blossoming of the field of DNA nanotechnology, with a broad range of applications in biotechnology, biosensors, diagnostics, and drug delivery. These applications require effi ... Full text Cite

2.5 Elastin-like polypeptides

Book section · January 1, 2017 Elastin-like polypeptides are a family of stimuli-responsive biopolymers that have been extensively studied for biomedical applications. Derived from tropoelastin, they mimic many of elastin’s remarkable material properties, yet can be designed with a mole ... Full text Cite

Design of Sequence-Specific Polymers by Genetic Engineering

Book section · January 1, 2017 Protein polymers are macromolecules of repeats of one or more amino acids that are arranged in a precisely defined sequence. The precise arrangement of their repeat units and their precisely defined length distinguish protein polymers from their synthetic ... Full text Cite

Elastin-Like Polypeptides: Bio-Inspired Smart Polymers for Protein Purification, Drug Delivery and Tissue Engineering

Book section · January 1, 2016 Elastin-Like Polypeptides (ELPs) have several interesting properties that are relevant to their use in biotechnology and medicine. ELPs have several interesting properties that are relevant to their use in biotechnology and medicine. First, ELPs exhibit re ... Full text Cite

Surface Patterning

Book section · January 1, 2013 Full text Cite

Individual plasmonic nanostructures as label free biosensors

Book section · January 1, 2012 This chapter reviews our work and that of other groups in the use of individual plasmonic nanostructures that are presented by a substrate for the labelfree detection of biomolecular binding events. This class of single particle nanosensors is based on the ... Full text Cite