Scholars@Duke
Ashutosh Chilkoti

Ashutosh Chilkoti

Alan L. Kaganov Distinguished Professor of Biomedical Engineering
Biomedical Engineering
Box 90281, Durham, NC 27708-0281
3381 CIEMAS, Durham, NC 27708

Scholarly Works - Conferences

Abstract 4481: Genetically encoded chimeric polypeptide nanoparticles for gemcitabine delivery to solid tumors

Conference Cancer Research · October 1, 2014 AbstractGemcitabine (2′,2′-difluorodeoxycytidine) (dFdC) is a chemotherapeutic drug indicated for the treatment of pancreatic, bladder, NSCLC, breast and ovarian cancers. The use of gemcitabine for the treat ... Full text Cite

Abstract 4583: In situ photocontrolled intratumoral depot for combined photodynamic therapy and brachytherapy for solid tumor

Conference Cancer Research · October 1, 2014 AbstractIntratumoral (i.t.) drug delivery can circumvent the transport barriers_high intratumoral fluid pressure and irregular vascularization_of solid tumors that limit the effectiveness of systemically del ... Full text Cite

Surface initiated polymerization and its applications in medicine

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · August 10, 2014 Link to item Cite

Genetically encoded polypeptide nanoparticles for delivery of drugs

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · March 16, 2014 Link to item Cite

The language of protein polymers

Conference ACS Symposium Series · January 1, 2014 Proteins are heteropolymers of one or more amino acid residues arranged in a molecularly defined fashion. The precise control of amino acid sequence in protein biosynthesis programs the folding of these heteropolymers into diverse three-dimensional structu ... Full text Cite

Genetically engineered polypeptide conjugates and fusions for drug delivery

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · September 8, 2013 Link to item Cite

Enzyme catalyzed polymerization of DNA amphiphiles that self-assemble into star-like micelles

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · September 8, 2013 Link to item Cite

Syntax of "smart" peptide polymers governs their function

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · September 8, 2013 Link to item Cite

Elastin-based amphiphilic copolymers as precision building blocks for controlled self-assembly

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · September 8, 2013 Link to item Cite

Interactions of elastin-like polypeptides with model membranes on GUVs

Conference EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS · July 1, 2013 Link to item Cite

Abstract 5615: Evaluation of the antitumoral efficacy and toxicity of injectable, polymeric radionuclide seeds in a noninvasive preclinical prostate tumor model.

Conference Cancer Research · April 15, 2013 AbstractBrachytherapy continues to be one of the predominant radiotherapy modalities for the treatment of prostate cancer. Depending on the stage of the cancer, it is employed either as a stand-alone treatme ... Full text Cite

Abstract 4509: Genetically encoded chimeric polypeptide nanoparticles for paclitaxel delivery to triple negative breast cancer.

Conference Cancer Research · April 15, 2013 AbstractTriple negative breast cancer (TNBC) represents an important clinical challenge, because TNBC, like other breast cancer subtypes is highly metastatic, but TNBC displays a shorter median time to relap ... Full text Cite

Abstract 4341: A novel injectable polymer liquid that self-assembles into radioactive “seeds” for brachytherapy.

Conference Cancer Research · April 15, 2013 AbstractBrachytherapy seeds are made by sealing radionuclides in metal or other non-degradable material (resin or glass) and surgically implanted into the tumor tissue. Brachytherapy has shown some efficacy ... Full text Cite

Delivery of paclitaxel with elastin-like polypeptides

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · April 7, 2013 Link to item Cite

Biomolecular toolbox for the in situ synthesis of protein-polymer conjugates

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · August 19, 2012 Link to item Cite

Field-induced nanolithography for the patterning of non-fouling polymer brushes

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · March 25, 2012 Link to item Cite

Genetically encoded stimulus responsive elastin-like polypeptides: Applications in drug delivery

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · March 25, 2012 Link to item Cite

Designing interfaces for optical biosensors

Conference Optics Infobase Conference Papers · January 1, 2009 I will describe two interfaces for optical biosensors: (1) a label-free biosensor that exploits the local surface plasmon resonance of noble metal nanostructures; and (2) a polymer brush interface on glass that abolishes non-specific adsorption leading to ... Full text Cite

PMSE 446-Architecture of polymer-drug conjugate controls in vivo fate and efficacy

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · August 17, 2008 Link to item Cite

PMSE 206-Architecture of polymer-drug conjugate controls in vivo fate and efficacy

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · April 6, 2008 Link to item Cite

POLY 351-Thermally responsive elastin biopolymers for drug delivery

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · April 6, 2008 Link to item Cite

Materials Research Society Symposium Proceedings: Preface

Conference Materials Research Society Symposium Proceedings · December 1, 2004 Cite

Mechanics of stimulus-responsive elastin-like polypeptides studied by force spectroscopy.

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · August 22, 2004 Link to item Cite

3-D reconstruction of tumor vascular networks

Conference JOURNAL OF VASCULAR RESEARCH · January 1, 2004 Link to item Cite

Fabrication of "smart" protein nanostructures using molecular recognition and dip-pen nano-lithography.

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · September 1, 2003 Link to item Cite

Nanoparticle biosensors

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · March 1, 2003 Link to item Cite

Passive and active nonfouling polymer grafts.

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · March 1, 2003 Link to item Cite

Fabrication of surface confined, stimulus-responsive polymer nanostructures using dip-pen nanolithography.

Conference ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY · March 1, 2003 Link to item Cite