Bach Nguyen

Journal article J Am Chem Soc · February 4, 2026 Darobactins are ribosomally synthesized and post-translationally modified peptides (RiPPs) with potent activity against Gram-negative pathogens. Their antibiotic function depends on a distinctive β-strand architecture stabilized by an ether cross-link betw ... Full text Link to item Cite

Radical-Mediated Nucleophilic Peptide Cross-Linking in Dynobactin Biosynthesis.

Journal article J Am Chem Soc · November 20, 2024 Dynobactins are recently discovered ribosomally synthesized and post-translationally modified peptide (RiPP) antibiotics that selectively kill Gram-negative pathogens by inhibiting the β-barrel assembly machinery (Bam) located on their outer membranes. Suc ... Full text Link to item Cite