Barbara R. Shaw
William T. Miller Distinguished Professor Emeritus of Chemistry

Our laboratory studies the chemical reactivity of DNA and synthesizes modified nucleic acids as potential antitumor and antisense agents. We use biophysical, biochemical, and genetic techniques together with synthetic chemistry to understand pathways of mutation in DNA and to design novel nucleic acid analogues that might find use in the control of gene expression and signal transduction, in the treatment of tumors and cancer, and in antisense and gene therapy.

Current Appointments & Affiliations

Contact Information

  • 1105 French Family Science Ctr, Box 90346, Chemistry Department, Durham, NC 27708-0346
  • Box 90346, Durham, NC 27708-0346

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.