Journal articlePsychiatry Res · August 2026
Exposure to toxic substances has been linked to poorer mental health among U.S. military veterans broadly, but less is known about specific psychiatric outcomes, such as suicidal thoughts and behaviors (STBs). In the current observational cohort study, we ...
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Journal articleJ Am Heart Assoc · July 7, 2026
BACKGROUND: The ability to predict cardiometabolic risk is essential to support efforts to prevent future onset of disease. Biomarkers that assess biological aging-the rate of decline in physiological functioning that occurs across the systems of the human ...
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Journal articleJ Am Med Inform Assoc · July 1, 2026
OBJECTIVE: Phase II of MVP-CHAMPION, a federal collaboration between the Veterans Affairs Healthcare System (VA) and the Department of Energy (DoE), leveraged large-scale clinical, geo-spatial, and genetic data with state-of-the-art artificial intelligence ...
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Journal articleArch Suicide Res · June 23, 2026
OBJECTIVE: Combat has been related to suicidal thoughts and behaviors via increased PTSD and depression in prior work; however, such studies have been limited by sample size, reliance on self-report, failure to account for other disorders, and a limited fo ...
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Journal articleDrug Alcohol Depend · June 1, 2026
BACKGROUND: The insula helps regulate affective distress and plays a critical role in maintaining tobacco use disorder. Task-based functional connectivity underlying cognitive performance during affective distress has previously distinguished between curre ...
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Journal articleEBioMedicine · June 2026
BACKGROUND: Bipolar disorder (BD) is a major mood disorder influenced by both genetic and environmental factors. While DNA methylation from peripheral tissues can reflect both genetic and environmental influences and reveal insights into disease biology, i ...
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Journal articleNeurobiol Aging · May 29, 2026
Individuals with post-traumatic stress disorder (PTSD) are at higher risk for age-related physical comorbidities, such as cardiovascular disorders, and exhibit accelerated epigenetic and brain aging. The present study examined PTSD as a moderator of the as ...
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Journal articleJ Head Trauma Rehabil · May 2026
OBJECTIVE: Military service over the last several decades has been associated with an increased risk of injuries, including traumatic brain injury (TBI). Veterans with a history of TBI often experience poor health outcomes and have higher rates of prematur ...
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Journal articleJ Affect Disord · April 15, 2026
Suicide remains a critical concern within the United States, particularly among U.S. veterans. Anger is a known correlate of suicidal ideation (SI) but little is understood about their moment-to-moment relationship. This short communication uses ecological ...
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Journal articleJ Trauma Stress · April 2026
Dysregulated anger is a prevalent concern for veterans with posttraumatic stress disorder (PTSD) and is associated with negative psychosocial outcomes. The tendency to perceive ambiguous interpersonal situations as hostile, also known as hostile interpreta ...
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Journal articleJ Am Med Inform Assoc · April 1, 2026
OBJECTIVE: Predictive models of suicide risk have focused on features extracted from structured data found in electronic health records, with limited consideration of predisposing life events (LE) expressed in unstructured clinical text such as housing ins ...
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Journal articleJ Head Trauma Rehabil · March 18, 2026
OBJECTIVE: To determine whether lifetime blast exposure severity is independently associated with accelerated biological aging among post-9/11 Veterans. SETTING: Veterans Affairs medical centers in the southeastern United States. PARTICIPANTS: In total, 11 ...
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Journal articlePsychol Trauma · March 2026
OBJECTIVE: Interpersonal violence is a common barrier to reintegration into civilian life in post-9/11 veterans. Alcohol use and anger, also common among veterans, are both risk factors for violence. The present study used longitudinal data to examine rela ...
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Journal articleJ Affect Disord · January 15, 2026
BACKGROUND: Suicide is a leading cause of death among younger veterans; however, the genetic basis of suicide remains largely unknown. While prior genome-wide association studies (GWAS) have identified common variants associated with suicidal ideation and ...
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Journal articleBrain Behav Immun · January 2026
Posttraumatic stress disorder (PTSD) is associated with poor health. Prior research has shown stressful events are associated with inflammatory biomarkers, such as soluble urokinase plasminogen activator receptor (suPAR), suggesting systemic chronic inflam ...
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Journal articleJ Gen Intern Med · December 19, 2025
BACKGROUND: The Veterans Health Administration (VA) is committed to consistently addressing high rates of tobacco use among U.S. military veterans. OBJECTIVE: This study examined the extent to which social determinants of health (SDOH) were associated with ...
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Journal articleJ Psychiatr Res · November 2025
Exposure to toxins, such as pesticides, smoke from burning oil fields, and nerve gas, during military operations have been linked to poor physical health among veterans. However, less is known about how these exposures may affect mental health outcomes, es ...
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Journal articleInternational Journal of Mental Health and Addiction · October 1, 2025
Cannabis use problems are on the rise in the USA, and there is a significant need for novel approaches to increase heavy cannabis users’ access to evidence-based treatment. The objective of this randomized clinical trial (RCT) was to evaluate the efficacy ...
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Journal articleJ Psychiatr Res · September 2025
Epigenome-wide association studies (EWAS) have identified cytosine-phosphate-guanine sites (CpGs) associated with trauma and PTSD. However, prior studies have largely focused on cross-sectional associations, and it remains unclear whether epigenetic profil ...
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Journal articlePsychiatry Res · September 2025
Veterans die by suicide at almost twice the rate of non-veterans, and risks for suicide can be further increased after sustaining traumatic brain injury (TBI). This is notable, given that over 20 % of post-9/11 Veterans are estimated to have experienced TB ...
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Journal articlemedRxiv · August 24, 2025
Suicidal thoughts and behaviors originate from heterogeneous mechanisms, including behavioral disinhibition characteristic of "externalizing" disorders (e.g., substance use disorders, antisocial personality disorder, etc.). Prior work has demonstrated stro ...
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Journal articleNicotine Tob Res · August 22, 2025
INTRODUCTION: Certain psychiatric populations have especially low smoking cessation rates. This highlights the need to identify smoking treatments that increase cessation rates by addressing factors thought to impede their success. Behavioral activation (B ...
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Journal articleCognit Ther Res · July 22, 2025
PURPOSE: Insomnia, characterized by difficulty initiating or maintaining sleep, is a robust transdiagnostic correlate of suicidal ideation (SI). Nevertheless, there remains a lack of research exploring factors that may account for this association. One app ...
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Journal articleJ Gerontol A Biol Sci Med Sci · June 10, 2025
BACKGROUND: Epigenetic aging measures have promise as surrogate health outcomes in randomized control trials and observational cohort studies. The value of these measures, however, will reflect the extent to which they are associated with prospective healt ...
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Journal articleJ Clin Psychiatry · May 7, 2025
Objective: Antidepressants are commonly prescribed, yet understanding of consequences for cardiovascular disease (CVD) risk is less well-developed. We examined associations of antidepressants (selective serotonin reuptake inhibitors [SSRIs], serotonin nore ...
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Journal articleSuicide Life Threat Behav · April 2025
INTRODUCTION: Although nonsuicidal self-injury (NSSI) is more common among military veterans than adult civilians, little is known about NSSI disorder among veterans. METHOD: The present study explored NSSI characteristics among veterans meeting criteria f ...
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Journal articleJ Psychiatr Res · March 2025
The rate of death by suicide is elevated among Veterans of all eras. Chronic symptoms of pain, depression, and sleep disturbances are also common among Veterans, and these symptoms are associated with suicidal thoughts and behaviors. About 25% of the 697,0 ...
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Journal articleInt J Ment Health Addict · February 7, 2025
OBJECTIVE: Alcohol and cannabis use are each associated with suicidal thoughts and behaviors and nonsuicidal self-injury (NSSI) in military veterans, but less is known with regard to concurrent use. The present study compared U.S. veterans (N = 1098; 78% m ...
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Journal articleEur J Prev Cardiol · January 27, 2025
AIMS: Elevated lipoprotein(a) [Lp(a)] is a causal risk factor for atherosclerotic cardiovascular disease, but the mechanisms of risk are debated. Studies have found inconsistent associations between Lp(a) and measurements of atherosclerosis. We aimed to as ...
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Journal articleAnn Behav Med · January 4, 2025
BACKGROUND: Posttraumatic stress disorder (PTSD) is associated with chronic disease risk, particularly cardiovascular disease (CVD). However, few studies have combined detailed measurements of trauma exposure and PTSD with incident chronic disease outcomes ...
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Journal articleJ Gerontol A Biol Sci Med Sci · January 2, 2025
Injuries characterizing recent military service, such as traumatic brain injury and posttraumatic stress disorder, are linked to accelerated biological aging. If recent veterans have accelerated aging, they might also show early onset of aging-related phen ...
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Journal articleMil Psychol · 2025
Prior research has established the psychometric properties of the Critical Warzone Experiences (CWE) scale among post-9/11 Iraq/Afghanistan-era veterans; however, the psychometric properties of the CWE among Gulf War I-era veterans have not yet been establ ...
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Journal articleGenome Med · December 18, 2024
BACKGROUND: The occurrence of post-traumatic stress disorder (PTSD) following a traumatic event is associated with biological differences that can represent the susceptibility to PTSD, the impact of trauma, or the sequelae of PTSD itself. These effects inc ...
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Journal articlePsychol Trauma · December 2024
OBJECTIVE: Problematic anger is commonly reported among veterans with posttraumatic stress disorder (PTSD) and is associated with numerous psychosocial impairments. There is a clear need to develop innovative and effective anger interventions. One of the c ...
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Journal articleTraumatology · December 2024
ObjectiveAlthough not all trauma-exposed individuals develop posttraumatic stress disorder (PTSD) symptoms or NSSI, it has been suggested that those who use NSSI as a means of coping with PTSD symptoms increase their acquired capability for suicid ...
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Journal articleJ Psychiatr Res · December 2024
People with lower levels of social connection are at increased risk for suicidal thoughts and behaviors. This extends to populations at greater risk of death by suicide, including U.S. military veterans. Despite this well-established association, it is unc ...
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Journal articleContemp Clin Trials · November 2024
BACKGROUND: Nearly 2 million U.S. veterans live with co-occurring alcohol use disorder and posttraumatic stress disorder (AUD/PTSD). Extant AUD/PTSD treatments emphasize symptom reduction, sometimes overlooking psychosocial functioning improvements, and ha ...
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Journal articleJAMA Intern Med · November 1, 2024
IMPORTANCE: Cognitive behavioral therapy for insomnia (CBTi) is the standard of care for treating insomnia disorder, but access is limited. Alternative approaches are needed to expand access to the standard of care. OBJECTIVE: To examine the effectiveness ...
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Journal articleJ Gerontol A Biol Sci Med Sci · November 1, 2024
BACKGROUND: Sickle cell disease (SCD) is a chronic medical condition characterized by red blood cell sickling, vaso-occlusion, hemolytic anemia, and subsequently, end-organ damage and reduced survival. Because of this significant pathophysiology and early ...
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Journal articleCommun Biol · October 21, 2024
Genome-wide association studies (GWAS) identify genetic variants underlying complex traits but are limited by stringent genome-wide significance thresholds. We present GRIN (Gene set Refinement through Interacting Networks), which increases confidence in t ...
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Journal articleMil Psychol · September 2, 2024
Military sexual assault (MSA) is a prevalent issue among military personnel that has been linked to adverse mental and physical health outcomes, including posttraumatic stress disorder (PTSD) and suicidal thoughts and behaviors. The present study sought to ...
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Journal articlePsychol Trauma · September 2024
OBJECTIVES: Cognitive processing therapy (CPT) is an evidence-based psychotherapy for posttraumatic stress disorder (PTSD); however, little is known about how interrelationships between PTSD symptoms change over the course of treatment. The current study e ...
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Journal articleMol Psychiatry · August 2024
Persons diagnosed with schizophrenia (SCZ) or bipolar I disorder (BPI) are at high risk for self-injurious behavior, suicidal ideation, and suicidal behaviors (SB). Characterizing associations between diagnosed health problems, prior pharmacological treatm ...
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Journal articleAlzheimers Res Ther · June 29, 2024
BACKGROUND: Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are associated with self-reported problems with cognition as well as risk for Alzheimer's disease and related dementias (ADRD). Overlapping symptom profiles observed in cogni ...
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Journal articlePsychiatry Res · June 2024
Measures of epigenetic aging derived from DNA methylation (DNAm) have enabled the assessment of biological aging in new populations and cohorts. In the present study, we used an epigenetic measure of aging, DunedinPACE, to examine rates of aging across dem ...
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Journal articleJ Psychiatr Res · June 2024
Exposure to toxins-such as heavy metals and air pollution-can result in poor health and wellbeing. Recent scientific and media attention has highlighted negative health outcomes associated with toxic exposures for U.S. military personnel deployed overseas. ...
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Journal articleJ Subst Use Addict Treat · May 2024
INTRODUCTION: Alcohol use disorder (AUD) is prevalent among veterans, and excessive alcohol use is associated with significant mental and physical health consequences. Currently, the largest cohort of veterans seeking services at the VA are those from the ...
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Journal articleNat Genet · May 2024
Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has thus been limited. We performed a multi-ancestry ...
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Journal articleSci Rep · April 5, 2024
The Phenome-Wide Association Study (PheWAS) is increasingly used to broadly screen for potential treatment effects, e.g., IL6R variant as a proxy for IL6R antagonists. This approach offers an opportunity to address the limited power in clinical trials to s ...
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Journal articleJ Am Heart Assoc · March 5, 2024
BACKGROUND: Posttraumatic stress disorder (PTSD) has been associated with ischemic heart disease in women veterans, but evidence for associations with other cardiovascular disorders remains limited in this population. This retrospective longitudinal cohort ...
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Journal articleCrisis · March 2024
Background: Recent findings indicate that firefighters may be at increased risk for death by suicide; however, there has been only limited suicide prevention work in fire service to date. Aim: The objective of this program evaluation project was to develop ...
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Journal articlePsychiatry Res · March 2024
Cannabis use has been increasing over the past decade, not only in the general US population, but particularly among military veterans. With this rise in use has come a concomitant increase in cannabis use disorder (CUD) among veterans. Here, we performed ...
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Journal articleJAMA Psychiatry · February 1, 2024
IMPORTANCE: Many psychiatric outcomes share a common etiologic pathway reflecting behavioral disinhibition, generally referred to as externalizing (EXT) disorders. Recent genome-wide association studies (GWASs) have demonstrated the overlap between EXT dis ...
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Journal articleTransl Psychiatry · January 31, 2024
BACKGROUND: The causal effects of gut microbiome and the development of posttraumatic stress disorder (PTSD) are still unknown. This study aimed to clarify their potential causal association using mendelian randomization (MR). METHODS: The summary-level st ...
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Journal articleSci Rep · January 20, 2024
We present an ensemble transfer learning method to predict suicide from Veterans Affairs (VA) electronic medical records (EMR). A diverse set of base models was trained to predict a binary outcome constructed from reported suicide, suicide attempt, and ove ...
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Journal articleTransl Psychiatry · January 6, 2024
People who experience trauma and develop posttraumatic stress disorder (PTSD) are at increased risk for poor health. One mechanism that could explain this risk is accelerated biological aging, which is associated with the accumulation of chronic diseases, ...
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Journal articleArch Suicide Res · 2024
OBJECTIVE: Pain confers risk for suicidal thoughts and behaviors. Experiential avoidance (EA), which is relevant to both pain and suicide risk, has not been studied as a potential mechanism for this relationship. The present study tested the hypothesis tha ...
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Journal articleDeath Stud · 2024
Nonsuicidal self-injury (NSSI) is a robust predictor of suicide attempts. However, understanding of NSSI and associated treatment utilization among Veterans is limited. Although impairment may be assumed, few studies examine the association between NSSI an ...
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Journal articleArch Suicide Res · 2024
INTRODUCTION: Research indicates that being married is associated with reduced risk of suicide and self-directed violence (SDV) relative to being divorced. Simultaneously, difficulties within relationships predict poorer health outcomes. However, research ...
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Journal articleBehav Ther · January 2024
Many interventions for cannabis use disorder (CUD) are associated with decreases in frequency and quantity of use but fail to increase overall rates of sustained abstinence. It is currently unknown whether reductions in use (in the absence of sustained abs ...
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Journal articleBehav Sleep Med · 2024
OBJECTIVES: Obstructive sleep apnea (OSA) among veterans is frequently underdiagnosed and undertreated. The present study sought to: 1) characterize the prevalence and rate of treatment of OSA among VA users and non-users and 2) examine the associations be ...
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Journal articleJACC Adv · January 2024
BACKGROUND: Post-traumatic stress disorder (PTSD) is associated with increased rates of incident ischemic heart disease (IHD) in women. OBJECTIVES: The purpose of this study was to determine mechanisms of the PTSD-IHD association in women. METHODS: In this ...
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Journal articlePLoS One · 2024
Tobacco-related deaths remain the leading cause of preventable death in the United States. Veterans suffering from posttraumatic stress disorder (PTSD)-about 11% of those receiving care from the Department of Veterans Affairs (VA)-have triple the risk of d ...
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Book section · January 1, 2024
The International Classification of Diseases and Diagnostic and Statistical Manual of Mental Disorders, published by the World Health Organization and American Psychiatric Association, respectively, identify multiple psychiatric disorders specifically asso ...
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Journal articleJ Am Med Inform Assoc · December 22, 2023
OBJECTIVE: To apply deep neural networks (DNNs) to longitudinal EHR data in order to predict suicide attempt risk among veterans. Local explainability techniques were used to provide explanations for each prediction with the goal of ultimately improving ou ...
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Journal articleJ Assoc Res Otolaryngol · December 2023
PURPOSE: Chronic age-related imbalance is a common cause of falls and subsequent death in the elderly and can arise from dysfunction of the vestibular system, an elegant neuroanatomical group of pathways that mediates human perception of acceleration, grav ...
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Journal articlePsychiatry Res · November 2023
Nonsuicidal self-injury (NSSI) is a debilitating concern among U.S. veterans, with wall/object-punching commonly endorsed as an NSSI method. We examined how this behavior relates to other NSSI methods and psychosocial outcomes. We conducted a latent class ...
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Journal articleJAMA Netw Open · October 2, 2023
IMPORTANCE: Cardiovascular disease (CVD) remains the leading cause of death in the US. Women veterans have higher rates of CVD compared with civilian US women; however, analyses of recent trends in mortality from cardiac disease for women veterans are lack ...
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Journal articlePrev Med Rep · October 2023
Tobacco cessation is reduced in U.S. military veterans experiencing homelessness. Mobile contingency management (mCM) is a promising treatment for tobacco use among populations experiencing homelessness, but past CM studies have largely been small, have re ...
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Journal articleAm J Psychiatry · October 1, 2023
OBJECTIVE: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale genome-wide association studies (GWASs) recently discovered and cross-validated genome-wide significant (GWS) loci for suicide attempt (SA). The present stud ...
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Preprint · September 8, 2023
Tobacco-related deaths exceed those resulting from homicides, suicides, motor vehicle accidence, alcohol consumption, illicit substance use, and acquired immunodeficiency syndrome (AIDS), combined. Amongst U.S. veterans, this trend is particularly concerni ...
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Journal articleDrug Alcohol Depend Rep · September 2023
BACKGROUND: Shame and guilt are key emotions known to amplify trauma-related symptoms in veterans. Maintenance of symptoms is facilitated by avoidance behaviors, such as substance use. However, limited research has examined the associations between shame, ...
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Journal articleSuicide Life Threat Behav · August 2023
INTRO: Nonsuicidal self-injury (NSSI) is associated with marked functional impairment and is a robust predictor of suicide attempts. Prevalence rates of NSSI, and self-directed violence more broadly, are elevated among military veterans. Despite the inclus ...
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Journal articlemedRxiv · July 11, 2023
BACKGROUND: Many psychiatric outcomes are thought to share a common etiological pathway reflecting behavioral disinhibition, generally referred to as externalizing disorders (EXT). Recent genome-wide association studies (GWAS) have demonstrated the overlap ...
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Journal articleJ Psychosom Res · July 2023
OBJECTIVE: Posttraumatic stress disorder (PTSD) is associated with elevated risk of coronary heart disease (CHD); however, the effects of PTSD treatment on CHD biomarkers is unknown. This study examined whether cognitive processing therapy (CPT) improves 2 ...
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ConferenceSleep · June 13, 2023
STUDY OBJECTIVES: Prior work has established associations between post-traumatic stress disorder (PTSD), disrupted sleep, and cardiovascular disease (CVD), but few studies have examined health correlates of nightmares beyond risks conferred by PTSD. This s ...
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Journal articleInt J Cogn Ther · April 14, 2023
Experiential avoidance (EA) is associated with posttraumatic stress disorder (PTSD) and self-injurious thoughts and behaviors (SITBs) across different populations, and extant literature has demonstrated a strong relationship between PTSD and SITBs. However ...
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Journal articlemedRxiv · March 8, 2023
OBJECTIVE: Persons diagnosed with schizophrenia (SCZ) or bipolar I disorder (BPI) are at high risk for self-injurious behavior, suicidal ideation, and suicidal behaviors (SB). Characterizing associations between diagnosed mental and physical health problem ...
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Journal articlePLoS Genet · March 2023
Suicidal ideation (SI) often precedes and predicts suicide attempt and death, is the most common suicidal phenotype and is over-represented in veterans. The genetic architecture of SI in the absence of suicide attempt (SA) is unknown, yet believed to have ...
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Journal articleBiol Psychiatry · February 15, 2023
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) and posttraumatic stress disorder (PTSD) are associated, but it is unclear if this is a causal relationship or confounding. We used genetic analyses and sibling comparisons to clarify the directio ...
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Journal articleJAMA Psychiatry · February 1, 2023
IMPORTANCE: Suicide is a leading cause of death; however, the molecular genetic basis of suicidal thoughts and behaviors (SITB) remains unknown. OBJECTIVE: To identify novel, replicable genomic risk loci for SITB. DESIGN, SETTING, AND PARTICIPANTS: This ge ...
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Journal articleJ Psychiatr Res · February 2023
Traumatic experiences and genetic heritability are among the most widely acknowledged risk factors leading to the development of psychopathology; including posttraumatic stress disorder (PTSD) and major depressive disorder (MDD). The purpose of this study ...
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Journal articleContemp Clin Trials · February 2023
BACKGROUND: Cognitive Behavioral Therapy for Insomnia (CBTi) is recommended as first-line treatment for insomnia, yet patient access to CBTi is limited. Self-help CBTi could increase patient access. Self-help CBTI with provider sup]port is more effective a ...
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Journal articlePsychol Serv · 2023
Depression and posttraumatic stress disorder (PTSD) are two of the most common mental health conditions experienced by veterans. It is unclear what individual and system level factors are associated with receiving mental health treatment for these concerns ...
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Journal articleDeath Stud · 2023
Cannabis use has been indicated as a risk factor for suicide in veterans. This study of Gulf War veterans tested the relationship between self-report past year cannabis use and (a) past year suicidal ideation and (b) risk for suicidal behavior. Data were f ...
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Journal articleSleep Adv · 2023
STUDY OBJECTIVES: The purpose of this study was to (1) estimate trauma associated sleep disorder (TASD) prevalence among post-9/11 era veterans and to describe differences in service and comorbid mental health clinical characteristics among individuals wit ...
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Journal articleFront Psychiatry · 2023
INTRODUCTION: The U.S. suicide mortality rate has steadily increased during the past two decades, particularly among military veterans; however, the epigenetic basis of suicidal thoughts and behaviors (STB) remains largely unknown. METHODS: To address this ...
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Journal articleFront Psychiatry · 2023
INTRODUCTION: Despite a recent global decrease in suicide rates, death by suicide has increased in the United States. It is therefore imperative to identify the risk factors associated with suicide attempts to combat this growing epidemic. In this study, w ...
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Journal articleCirc Genom Precis Med · December 2022
BACKGROUND: The risk of arterial diseases may be elevated among family members of individuals having multifocal fibromuscular dysplasia (FMD). We sought to investigate the risk of arterial diseases in families of individuals with FMD. METHODS: Family histo ...
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Journal articlePsychol Med · December 2022
BACKGROUND: Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are commonly reported co-occurring mental health consequences of psychological trauma exposure. The disorders have high genetic overlap. Trauma is a complex phenotype but ...
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Journal articleComplement Ther Clin Pract · November 2022
Complementary and integrative health (CIH) approaches have gained empirical support and are increasingly being utilized among veterans to treat a myriad of conditions. A cluster of medically unexplained chronic symptoms including fatigue, headaches, joint ...
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Journal articleOphthalmology · November 2022
PURPOSE: Primary open-angle glaucoma (POAG) is a degenerative eye disease for which early treatment is critical to mitigate visual impairment and irreversible blindness. POAG-associated loci individually confer incremental risk. Genetic risk score(s) (GRS) ...
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Journal articleJ Psychiatr Res · September 2022
Suicide is a major public health problem affecting US Veterans and the US in general. Many variables (e.g., demographic, clinical, biological, geographic) have been associated with risk for suicide and suicidal behavior, including altitude; however, the ex ...
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Journal articlePsychiatry Res · September 2022
Nonsuicidal self-injury (NSSI) is a robust predictor of suicidal thoughts and behaviors; however, while there are typically only small differences observed in the prevalence of NSSI between men and women, this condition has been largely overlooked and unde ...
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Journal articleSuicide Life Threat Behav · August 2022
INTRODUCTION: Nonsuicidal self-injury (NSSI) is associated with significant impairment and is a robust predictor of suicidal ideation, attempts, and death by suicide; however, the present lack of a brief screening instrument for NSSI coupled with consisten ...
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Journal articleJ Trauma Stress · August 2022
Military sexual assault (MSA) is a prevalent issue among military personnel that can have direct implications on postmilitary mental health. Gulf War era U.S. veterans represent the first cohort in which women veterans were integrated into most aspects of ...
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Journal articlePsychiatry Res · August 2022
Prior research suggests a possible association between attention-deficit/hyperactivity disorder (ADHD) symptoms and nonsuicidal self-injury (NSSI) in veterans. However, this association has not yet been replicated. The present study sought to replicate and ...
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Journal articleContemp Clin Trials · August 2022
BACKGROUND: Smoking is a prevalent concern among Veterans, especially those with posttraumatic stress disorder (PTSD). Despite the availability of interventions for smoking cessation, these treatments have not been as effective among Veteran populations, p ...
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Journal articleBMC Med Genomics · July 6, 2022
BACKGROUND: Genome-wide Association Studies (GWAS) aims to uncover the link between genomic variation and phenotype. They have been actively applied in cancer biology to investigate associations between variations and cancer phenotypes, such as susceptibil ...
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Journal articleJ Affect Disord · July 1, 2022
BACKGROUND: Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are each common among Unites States (U.S.) military veterans and frequently co-occur (i.e., PTSD+AUD). Although comorbid PTSD+AUD is generally associated with worse outcomes re ...
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Journal articleJ Psychiatr Res · July 2022
The onset and persistence of life events (LE) such as housing instability, job instability, and reduced social connection have been shown to increase risk of suicide. Predictive models for suicide risk have low sensitivity to many of these factors due to u ...
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Journal articleJ Biomed Inform · June 2022
Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and irregular sampling o ...
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Journal articleSuicide Life Threat Behav · April 2022
BACKGROUND: The affective states most strongly associated with nonsuicidal self-injury (NSSI) remain poorly understood, particularly among veterans. This study used ecological momentary assessment (EMA) to examine relationships between affect ratings and N ...
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Journal articleBiol Psychiatry · April 1, 2022
BACKGROUND: Posttraumatic stress disorder (PTSD) is heritable and a potential consequence of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD phenotype measurement and incorporation of lifetime trauma exposure (LTE) info ...
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Journal articleJAMA Intern Med · April 1, 2022
IMPORTANCE: Coronavirus disease 2019 (COVID-19) confers significant risk of acute kidney injury (AKI). Patients with COVID-19 with AKI have high mortality rates. OBJECTIVE: Individuals with African ancestry with 2 copies of apolipoprotein L1 (APOL1) varian ...
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Journal articlePsychiatry Res · April 2022
Ecological momentary assessment (EMA) is a useful tool to investigate antecedents and consequences of nonsuicidal self-injury (NSSI), a robust predictor of Veteran suicide risk. Despite elucidating temporal changes among dynamic variables, EMA remains unde ...
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Journal articleMol Psychiatry · April 2022
To identify pan-ancestry and ancestry-specific loci associated with attempting suicide among veterans, we conducted a genome-wide association study (GWAS) of suicide attempts within a large, multi-ancestry cohort of U.S. veterans enrolled in the Million Ve ...
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Journal articlePsychol Trauma · March 2022
OBJECTIVE: Concurrent posttraumatic stress disorder and substance use disorder (PTSD/SUD) in U.S. military veterans represents an urgent public health issue associated with significant clinical challenges. Although previous research has shown that veterans ...
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Journal articleJ Psychiatr Res · March 2022
Nonsuicidal self-injury (NSSI) has been identified as one of the strongest predictors of suicide attempts. Wall/object punching is a particularly prevalent form of NSSI among male veterans that has been linked to both impulsivity and anger. The objective o ...
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Journal articleNicotine Tob Res · February 1, 2022
INTRODUCTION: Smokeless tobacco (ST) use and cessation rates have remained unchanged while cigarette smoking has declined, and cessation rates have increased. Text message programs have proved effective for cigarette smokers but have not been evaluated for ...
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Journal articlePain Med · February 1, 2022
OBJECTIVE: Depression and chronic pain are major problems in American veterans, yet there is limited long-term research examining how they relate to one another in this population. This study examined the relationship between depressive symptoms and pain i ...
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Journal articleBiol Psychiatry · February 1, 2022
BACKGROUND: Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared an ...
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Journal articlePsychosom Med · February 2022
OBJECTIVE: Heart rate variability (HRV) is a useful index of psychological and physiological stress. Although several wristband devices have purported to measure HRV, none have demonstrated reliability when compared with the criterion-standard Holter monit ...
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Journal articleTransl Psychiatry · December 16, 2021
The volume of subcortical structures represents a reliable, quantitative, and objective phenotype that captures genetic effects, environmental effects such as trauma, and disease effects such as posttraumatic stress disorder (PTSD). Trauma and PTSD represe ...
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Journal articleTransl Behav Med · December 14, 2021
Older veterans with posttraumatic stress disorder (PTSD) are at increased risk of obesity and cardiometabolic disease. Physical activity and healthy eating are two behaviors that impact health, functional independence, and disease risk in later life, yet f ...
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Journal articleJ Trauma Stress · December 2021
Veterans with posttraumatic stress disorder (PTSD) often experience high levels of hostility. Although studies have found that PTSD is associated with poorer quality of life (QoL), increased functional impairment, lower levels of social support, and increa ...
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Journal articleSuicide and Life Threatening Behavior · December 1, 2021
Objective: To determine in veterans whether severity of combat exposure was predictive of subsequently receiving a suicide risk assessment (SRA), and whether this relationship was meditated by depression symptomatology. Method: We conducted an electronic m ...
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Journal articleJ Health Psychol · November 2021
This study investigated prevalence and factors associated with prenatal smoking among US women veterans using cross-sectional data from a cohort study of veterans from recent wars utilizing Veterans Health Administration primary care (N = 6190). Among the ...
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Journal articlePsychol Serv · November 2021
Sexual assault is associated with increased psychological distress. It is possible that military sexual assault (MSA) is associated with heightened psychological distress compared to adult sexual assault that occurs pre- or postmilitary service due to the ...
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Journal articleJ Interpers Violence · October 2021
Difficulty controlling anger is a significant concern among combat veterans with posttraumatic stress disorder (PTSD), yet few controlled studies have examined the efficacy of anger treatments for this population. This study examined the effects of a group ...
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Journal articleJ Psychiatr Res · October 2021
A substantial minority of deployed Gulf War veterans developed posttraumatic stress disorder (PTSD), depression, and several chronic illnesses. Although military combat and exposure to certain nuclear, biological, and chemical agents (NBCs) increase risk f ...
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Journal articlePLoS Med · August 2021
BACKGROUND: Worldwide, nearly 800,000 individuals die by suicide each year; however, longitudinal prediction of suicide attempts remains a major challenge within the field of psychiatry. The objective of the present research was to develop and evaluate an ...
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Journal articleNicotine Tob Res · June 8, 2021
INTRODUCTION: The high smoking prevalence amongst individuals with psychiatric disorders constitutes a major public health disparity. Negative reinforcement models of addiction posit that severe tobacco withdrawal symptoms, related to the affective vulnera ...
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Journal articleJAMA Cardiol · June 1, 2021
IMPORTANCE: Posttraumatic stress disorder (PTSD) is associated with greater risk of ischemic heart disease (IHD) in predominantly male populations or limited community samples. Women veterans represent a growing, yet understudied, population with high leve ...
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Journal articleJ Psychiatr Res · June 2021
Suicidal ideation (SI) is a prevalent issue in the veteran population. A number of factors have been identified as risk factors for suicidal ideation (SI) in veterans, including suicide attempts, depression, posttraumatic stress disorder (PTSD), and drug u ...
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Journal articleJ Psychiatr Res · June 2021
An association has been found between cannabis use disorder (CUD) and violence in several clinical populations, including veterans with posttraumatic stress disorder (PTSD), and there is evidence that CUD has been increasing among veterans since September ...
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Journal articleNicotine Tob Res · May 24, 2021
INTRODUCTION: Smoking cessation mobile health (mHealth) programs are effective and have been recommended for integration into health care services but have not been evaluated in real-world health care settings. The Veterans Health Administration, a safety ...
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Journal articleJ Affect Disord · May 15, 2021
BACKGROUND: Expanding on research that has identified nonsuicidal self-injury (NSSI) as a strong predictor of suicide risk, the present study examined NSSI disorder (NSSID) and borderline personality disorder (BPD) as unique contributors to lifetime suicid ...
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Journal articleNat Commun · May 10, 2021
Serum concentration of hepatic enzymes are linked to liver dysfunction, metabolic and cardiovascular diseases. We perform genetic analysis on serum levels of alanine transaminase (ALT), alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) using ...
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Journal articleJ Psychiatr Res · May 2021
Up to 14% of veterans engage in nonsuicidal self-injury (NSSI) in their lifetime and this behavior is a relatively strong predictor of suicidal behavior compared to other identified risk factors. Further, NSSI is a clinically relevant behavior in its own r ...
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Journal articleNat Med · April 2021
Drug repurposing provides a rapid approach to meet the urgent need for therapeutics to address COVID-19. To identify therapeutic targets relevant to COVID-19, we conducted Mendelian randomization analyses, deriving genetic instruments based on transcriptom ...
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Journal articleContemp Clin Trials · March 2021
Posttraumatic stress disorder (PTSD) has been associated with accelerated progression of coronary heart disease (CHD). However, the underlying pathophysiological pathway has remained elusive and it is unclear whether there is a direct link between PTSD and ...
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Journal articleJ Psychiatr Res · March 2021
Veterans have high rates of suicide, and nonsuicidal self-injury (NSSI) is one of the strongest predictors of suicide risk; however, there is presently little known about antecedents of NSSI that might inform intervention efforts. Accumulating research sug ...
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Journal articlePain Med · February 23, 2021
OBJECTIVE: Chronic pain is common in military veterans with traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD). Neurofeedback, or electroencephalograph (EEG) biofeedback, has been associated with lower pain but requires frequent travel ...
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Journal articleAlzheimers Res Ther · February 4, 2021
BACKGROUND: Identification of genetic risk factors that are shared between Alzheimer's disease (AD) and other traits, i.e., pleiotropy, can help improve our understanding of the etiology of AD and potentially detect new therapeutic targets. Previous epidem ...
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Journal articlePsychiatry Res · February 2021
With its recent inclusion in the Diagnostic and Statistical Manual, nonsuicidal self-injury disorder (NSSID) has received limited research attention, especially in samples of military veterans. The present study sought to identify diagnostic predictors of ...
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Journal articleClin Psychol Psychother · January 2021
Moral injury merits further study to clarify its identification, prevalence, assessment and intersection with psychosocial and psychiatric problems. The present study investigated the screening potential of the Brief Moral Injury Screen (BMIS) in a sample ...
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Journal articlePLoS One · 2021
BACKGROUND: The risk factors associated with the stages of Coronavirus Disease-2019 (COVID-19) disease progression are not well known. We aim to identify risk factors specific to each state of COVID-19 progression from SARS-CoV-2 infection through death. M ...
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Journal articleFront Neurosci · 2021
Growing research suggests that posttraumatic stress disorder (PTSD) may be a risk factor for poor cardiovascular health, and yet our understanding of who might be at greatest risk of adverse cardiovascular outcomes after trauma is limited. In this study, w ...
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Journal articleFront Neurosci · 2021
Posttraumatic stress disorder (PTSD) is a complex psychiatric disorder that can develop following exposure to traumatic events. The Psychiatric Genomics Consortium PTSD group (PGC-PTSD) has collected over 20,000 multi-ethnic PTSD cases and controls and has ...
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Journal articleWomens Health Issues · 2021
INTRODUCTION: Military sexual trauma (MST)-exposure to sexual harassment or assault during military service-is a major health priority for the Veterans Health Administration (VHA). We examined the health correlates of MST in the largest sample of U.S. wome ...
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Journal articleSubst Abuse · 2021
Alcohol and tobacco are the 2 most frequently used drugs in the United States and represent the highest co-occurrence of polysubstance use. The objective of this study was to refine an intervention combining mobile contingency management with cognitive-beh ...
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Journal articleJ Clin Psychol · December 2020
OBJECTIVE: This study explored the boundaries of the proposed diagnostic criteria for nonsuicidal self-injury disorder (NSSID) as outlined in the Conditions for Further Study section of the Diagnostic and Statistical Manual, Fifth Edition. We sought to fal ...
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Journal articleSuicide Life Threat Behav · December 2020
OBJECTIVE: Previous studies of military veterans have produced mixed findings regarding whether combat exposure is directly related to suicidal ideation or is indirectly related to suicidal ideation via its influence on other factors. The present study use ...
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Journal articleNat Commun · November 24, 2020
Epigenetic differences may help to distinguish between PTSD cases and trauma-exposed controls. Here, we describe the results of the largest DNA methylation meta-analysis of PTSD to date. Ten cohorts, military and civilian, contribute blood-derived DNA meth ...
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Journal articleJ Gerontol A Biol Sci Med Sci · October 15, 2020
BACKGROUND: Military veterans living with post-traumatic stress disorder (PTSD) face significant physical and functional health disparities, which are often aggravated over time and in the context aging. Evidence has shown that physical activity can positi ...
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Journal articleJ Behav Med · October 2020
Previous research has shown that African Americans (AA) report higher pain intensity and pain interference than other racial/ethnic groups as well as greater levels of other risk factors related to worse pain outcomes, including PTSD symptoms, pain catastr ...
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Journal articleJournal of traumatic stress · October 2020
Difficulty controlling anger is the most commonly reported reintegration concern among veterans with posttraumatic stress disorder (PTSD). One of the mechanisms associated with problematic anger is a tendency to interpret ambiguous interpersonal situations ...
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Journal articleJ Dual Diagn · October 2020
The objective of this study was to investigate the feasibility and acceptability of a multi-component mobile contingency management (CM) pilot intervention for smoking cessation for people with schizophrenia. Methods: This intervention included mobile CM ( ...
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Journal articleJ Behav Med · August 2020
Exercise training positively impacts mental health, yet remains untested in older adults with posttraumatic stress disorder (PTSD). We conducted a randomized controlled pilot trial to test the feasibility and acceptability of exercise training in older vet ...
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Journal articleEur J Psychotraumatol · July 29, 2020
Behavioural, structural, and functional neuroimaging have implicated the hippocampus as a critical brain region in posttraumatic stress disorder (PTSD) pathogenesis. Recent work in a normative, primarily European, sample identified 15 unique genetic loci c ...
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Journal articleNeuropsychopharmacology · July 2020
Posttraumatic stress disorder (PTSD) may develop when mechanisms for making accurate distinctions about threat relevance have gone awry. Generalization across conceptually related objects has been hypothesized based on clinical observation in PTSD, but the ...
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Journal articleNat Genet · July 2020
We investigated type 2 diabetes (T2D) genetic susceptibility via multi-ancestry meta-analysis of 228,499 cases and 1,178,783 controls in the Million Veteran Program (MVP), DIAMANTE, Biobank Japan and other studies. We report 568 associations, including 286 ...
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Journal articleAssessment · June 2020
In this study, we examined the validity of the Personality Assessment Inventory Alcohol (ALC) scale in 736 male veterans presenting for formal evaluation of posttraumatic stress disorder (PTSD). The ALC scale exhibited convergence with other measures of al ...
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Journal articleJ Affect Disord · May 15, 2020
BACKGROUND: Theoretical models and cross-sectional empirical studies of suicide indicate that anger is a factor that may help explain the association between posttraumatic stress disorder (PTSD) and suicide, but to date no longitudinal studies have examine ...
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Journal articleJ Aggress Maltreat Trauma · April 10, 2020
Although military sexual assault (MSA) has been well-established as a risk factor for psychopathology (e.g., PTSD, depression), little research has examined the association between MSA and self- and other-directed violence. Furthermore, there has been a gr ...
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Journal articleScience · March 20, 2020
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide associati ...
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Journal articleClin Epigenetics · March 14, 2020
BACKGROUND: Previous studies using candidate gene and genome-wide approaches have identified epigenetic changes in DNA methylation (DNAm) associated with posttraumatic stress disorder (PTSD). METHODS: In this study, we performed an EWAS of PTSD in a cohort ...
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Journal articleBiol Psychiatry Cogn Neurosci Neuroimaging · March 2020
BACKGROUND: The amygdala is a subcortical structure involved in socioemotional and associative fear learning processes relevant for understanding the mechanisms of posttraumatic stress disorder (PTSD). Research in animals indicates that the amygdala is a h ...
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Journal articleTransl Psychiatry · February 10, 2020
To investigate how unpredictable threat during goal pursuit impacts fronto-limbic activity and functional connectivity in posttraumatic stress disorder (PTSD), we compared military veterans with PTSD (n = 25) vs. trauma-exposed control (n = 25). Participan ...
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Book section · February 3, 2020
Over the past two decades, considerable research attention has focused on examining the role of anger in posttraumatic stress disorder (PTSD). Anger has been consistently associated with PTSD across populations, with the strongest associations found in mil ...
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Journal articleNeuropsychopharmacology · February 2020
Combat-exposed Veterans are at increased risk for developing psychological distress, mood disorders, and trauma and stressor-related disorders. Trauma and mood disorders have been linked to alterations in brain volume, function, and connectivity. However, ...
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Journal articleJ Health Psychol · 2020
Women may be disproportionately vulnerable to acute pain, potentially due to their social landscape. We examined whether positive and negative social processes (social support and social undermining) are associated with acute pain and if the processes are ...
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Journal articleTraumatology · January 1, 2020
People with anxiety-related disorders often engage in safety behaviors: overt or covert actions performed to prevent the occurrence of a feared outcome and/or reduce associated distress. Although clinical experience and conceptual models of posttraumatic s ...
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Journal articleJ Affect Disord · January 1, 2020
BACKGROUND: This study investigates the empirical association between psychosocial protective factors and subsequent suicidal ideation in veterans. METHODS: We conducted a national longitudinal survey in which participants were randomly drawn from over one ...
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Journal articleQual Health Res · December 2019
The objective of this study was to identify common themes among women veterans who smoke or recently quit and had used smoking cessation treatment within the Veterans Health Administration (VHA). The study built upon previous research by utilizing in-depth ...
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Journal articleDrug Alcohol Depend · December 1, 2019
BACKGROUND: Cigarette smoking is robustly associated with attention-deficit/hyperactivity disorder (ADHD), but little is known about psychological mechanisms accounting for this comorbid relationship. This study examined difficulties in emotion regulation, ...
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Journal articleTransl Behav Med · November 25, 2019
Patient-reported outcome (PRO) measures are particularly important in mental health services because patients are the central and essential source of information about their mental health status. PRO measures have the potential to engage patients in meanin ...
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Journal articleNat Commun · October 8, 2019
The risk of posttraumatic stress disorder (PTSD) following trauma is heritable, but robust common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD cases and 170,000 controls we conduct a genome-wide association study ...
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Journal articleAm J Hum Genet · October 3, 2019
Large-scale multi-ethnic cohorts offer unprecedented opportunities to elucidate the genetic factors influencing complex traits related to health and disease among minority populations. At the same time, the genetic diversity in these cohorts presents new c ...
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Journal articleJ Psychophysiol · October 2019
Autonomic dysfunction, in particular under-regulation of heart rate (HR) by the baroreflex, is implicated in development of insulin resistance (IR). According to reactivity hypothesis, sympathetic response to stressors may be more sensitive at predicting I ...
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Journal articleWomens Health Issues · June 25, 2019
BACKGROUND: Chronic pain conditions are common among both male and female Iraq/Afghanistan-era veterans and can have substantial negative impacts on quality of life and function. Although in general women tend to report higher levels of pain intensity than ...
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Journal articleWomens Health Issues · June 25, 2019
BACKGROUND: The Department of Veterans Affairs Million Veteran Program (MVP) is the largest ongoing cohort program of its kind, with 654,903 enrollees as of June 2018. The objectives of this study were to examine gender differences in the MVP cohort with r ...
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Journal articleJ Affect Disord · June 15, 2019
BACKGROUND: Posttraumatic stress disorder (PTSD) and negative affect (e.g., anger, depression, anxiety), are highly co-occurring. It remains unclear whether changes in PTSD symptoms subsequently impact negative affect, or vice versa. This study assessed as ...
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Journal articleJAMA Netw Open · May 3, 2019
IMPORTANCE: There is a well-established negative association of educational attainment (EA) and other traits related to cognitive ability with posttraumatic stress disorder (PTSD), but the underlying mechanisms are poorly understood. OBJECTIVES: To investi ...
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Journal articlePsychol Serv · May 2019
This study evaluated whether a history of traumatic brain injury (TBI) was associated with increased risk for recent suicidal ideation (SI) after accounting for demographics, depression, posttraumatic stress disorder (PTSD), and sleep quality. In terms of ...
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Journal articlePsychiatry Res · April 2019
Around half of Iraq and Afghanistan war veterans with traumatic brain injury (TBI) have co-occurring posttraumatic stress disorder (PTSD). Research on the differences between male and female veterans with co-occurring PTSD/TBI is sparse. This study evaluat ...
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Journal articleBehav Ther · March 2019
The objective of this study was to use qualitative methodology to tailor and refine an existing smoking cessation intervention for the population of people who use cigarettes and are diagnosed with schizophrenia, schizoaffective, or psychotic disorder. Suc ...
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Journal articleAddict Behav · March 2019
AIMS: Compared to the general U.S. population, military veterans and those living in rural areas disproportionately smoke cigarettes at higher rates, leading to increased health consequences. In the current study, prevalence and severity of cigarette smoki ...
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Journal articlePsychiatry Res · February 2019
Despite accumulated evidence linking trauma exposure to major depressive disorder (MDD), there is limited understanding as to why some trauma survivors subsequently develop MDD. The behavioral model of depression points to a negative reinforcement cycle of ...
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Journal articleJ Trauma Stress · February 2019
U.S. veterans are at increased risk for suicide compared to their civilian counterparts and account for approximately 20% of all deaths by suicide. Posttraumatic stress disorder (PTSD) and borderline personality features (BPF) have each been associated wit ...
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Journal articleJ Affect Disord · January 15, 2019
BACKGROUND: Suicidal ideation is a problem that disproportionately affects veterans. Moreover, veterans with posttraumatic stress disorder (PTSD) appear to be at particularly high risk for suicide. OBJECTIVE: The purpose of the present research was to exam ...
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Journal articleBehav Sleep Med · 2019
Objective/Background: Despite a well-established role of guilt cognitions in the maintenance and treatment of posttraumatic stress disorder (PTSD), relationships of guilt cognitions to nightmares are not well understood. This study investigated the ways in ...
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Journal articleArch Suicide Res · 2019
The objective of the present study was to use retrospective data to test the hypothesis that cannabis dependence would be associated with an increased rate of post-deployment suicide attempts. Participants included 319 veterans who had deployed to either I ...
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Journal articleJ Head Trauma Rehabil · 2019
OBJECTIVE: To investigate effects of cognitive rehabilitation with mobile technology and social support on veterans with traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD). PARTICIPANTS: There were 112 dyads, comprised by a veteran and a ...
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Journal articleAnxiety Stress Coping · January 2019
BACKGROUND/OBJECTIVES: Inner-city Black women may be more susceptible to posttraumatic stress disorder (PTSD) than White women, although mechanisms underlying this association are unclear. Living in urban neighborhoods distinguished by higher chronic stres ...
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Journal articleJ Addict Med · 2019
OBJECTIVE/BACKGROUND: Posttraumatic stress disorder (PTSD) and smoking are often comorbid. Combining PTSD and smoking cessation treatments could increase access to each treatment and could provide improved rates of smoking cessation through reductions in P ...
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Journal articleEur J Psychotraumatol · 2019
Objective: Although Combat exposure is associated with a range of psychiatric outcomes, many veterans do not develop psychopathology. Resilience is a multifaceted construct associated with reduced risk of distress and psychopathology; however, few studies ...
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Journal articleMil Behav Health · 2019
The present study describes the knowledge about smoking and nicotine among a sample of current Iraq-/Afghanistan-era veterans who smoke (N = 117). A majority of participants had knowledge regarding general risks of smoking and benefits of nicotine replacem ...
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Journal articleArch Phys Med Rehabil · December 2018
OBJECTIVE: To characterize behavioral and health outcomes in veterans with traumatic brain injury (TBI) acquired in nondeployment and deployment settings. DESIGN: Cross-sectional assessment evaluating TBI acquired during and outside of deployment, mental a ...
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Journal articleJ Affect Disord · December 1, 2018
BACKGROUND: Posttraumatic stress is associated with elevated risk for cardiovascular disease (CVD). Relatively little research, particularly among women, has documented mechanisms by which PTSD might confer CVD risk during early adulthood. The purpose of t ...
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Journal articleSleep · December 1, 2018
STUDY OBJECTIVES: To determine whether high-frequency heart rate variability (HF-HRV) during sleep differs between those with and without posttraumatic stress disorder (PTSD) as a function of sleep type (non-rapid eye movement [NREM] vs. rapid eye movement ...
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Journal articleClin J Pain · November 2018
BACKGROUND: Given high levels of traumatic stress for low-income, inner-city women, investigating the link between posttraumatic stress disorder (PTSD) and pain is especially important. PURPOSE: Using the conservation of resources theory, we investigated d ...
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Journal articlePsychiatry Res · November 2018
Death by suicide and suicidal behavior are major concerns among U.S. military veterans; however, no genome-wide association studies (GWAS) studies of suicidal behavior have been conducted among U.S. military veterans to date, despite the elevated rate of s ...
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Journal articleSuicide Life Threat Behav · October 2018
The present research investigated wall/object punching as a form of nonsuicidal self-injury (NSSI) among 1,143 veterans seeking treatment for posttraumatic stress disorder (PTSD). Wall/object punching was remarkably common in this sample (43%), and its inc ...
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Journal articleJournal of Smoking Cessation · September 1, 2018
We evaluated the feasibility of incorporating integrated care (IC) for smoking cessation into routine care for homeless veterans at seven Department of Veterans Affairs (VA) Medical Centers and the utility of the learning collaborative (LC) model in facili ...
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Journal articleMil Med · September 1, 2018
INTRODUCTION: In response to a strong focus on suicide prevention for all veterans, the Department of Veterans Affairs (VA) recently revised policy to provide emergency mental healthcare for veterans who received Other Than Honorable (OTH) discharges from ...
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Journal articleJAMA Cardiol · September 1, 2018
IMPORTANCE: Electronic health record (EHR) biobanks containing clinical and genomic data on large numbers of individuals have great potential to inform drug discovery. Individuals with interleukin 6 receptor (IL6R) single-nucleotide polymorphisms (SNPs) wh ...
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Journal articleJ Interpers Violence · August 2018
Military sexual trauma (MST) has been linked with increased rates of mental health disorders among veterans. Few studies have addressed how MST is related to use of VA and non-VA health care. The purpose of the current study was to (a) examine the associat ...
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Journal articleJ Affect Disord · August 1, 2018
BACKGROUND: Researchers have theorized that increased rates of suicide in the military are associated with combat exposure; however, this hypothesis has received inconsistent support in the literature, potentially because combat exposure may be indirectly ...
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Journal articleAdm Policy Ment Health · July 2018
This article examines the public safety rationale for a federal policy of prohibiting gun sales to veterans with psychiatric disabilities who are assigned a fiduciary to manage their benefits from the Department of Veterans Affairs. The policy was evaluate ...
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Journal articleJ Stud Alcohol Drugs · July 2018
OBJECTIVE: This study aimed to examine among veterans (a) whether alcohol consumption patterns are associated with probability of psychiatric symptoms and (b) whether an alcohol use disorder (AUD) history explains psychiatric symptoms among nondrinkers. ME ...
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Journal articlePsychoneuroendocrinology · June 2018
BACKGROUND: Recent studies examining the association between posttraumatic stress disorder (PTSD) and accelerated aging, as defined by DNA methylation-based estimates of cellular age that exceed chronological age, have yielded mixed results. METHODS: We co ...
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Journal articleAm J Cardiol · May 15, 2018
Moderate alcohol consumption has been associated with a lower risk of coronary artery disease (CAD) in the general population but has not been well studied in US veterans. We obtained self-reported alcohol consumption from Million Veteran Program participa ...
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Journal articlePsychol Serv · May 2018
Violence toward others has been identified as a serious postdeployment adjustment problem in a subset of Iraq- and Afghanistan-era veterans. In the current study, we examined the intricate links between posttraumatic stress disorder (PTSD), commonly cited ...
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Journal articleJ Am Heart Assoc · April 21, 2018
BACKGROUND: While adherence to healthful dietary patterns has been associated with a lower risk of coronary artery disease (CAD) in the general population, limited data are available among US veterans. We tested the hypothesis that adherence to Dietary App ...
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Journal articlePsychol Assess · April 2018
Suicide and violence are significant problems in a subset of Iraq/Afghanistan-era veterans. This study investigates how posttraumatic stress disorder (PTSD) and resilience in veterans are associated with suicidal ideation and violent impulses while control ...
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Journal articleAddict Behav · April 2018
INTRODUCTION: Cannabis is the most widely used illicit drug in the U.S. with 19.8 million current users. Population-based data indicate that almost all cannabis users (90%) have a lifetime history of tobacco smoking and the majority (74%) currently smoke t ...
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Journal articleTransl J Am Coll Sports Med · March 15, 2018
Posttraumatic stress disorder (PTSD) affects up to 30% of military veterans. Older veterans, many of whom have lived with PTSD symptoms for several decades, report a number of negative health outcomes. Despite the demonstrated benefits of regular exercise ...
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Journal articleMol Psychiatry · March 2018
The Psychiatric Genomics Consortium-Posttraumatic Stress Disorder group (PGC-PTSD) combined genome-wide case-control molecular genetic data across 11 multiethnic studies to quantify PTSD heritability, to examine potential shared genetic risk with schizophr ...
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Journal articlePsychiatry Res · March 2018
This study employed secondary analyses of existing ecological momentary assessment (EMA) data to characterize hostile and irritable affect in the day-to-day experience of 52 smokers with, and 65 smokers without, posttraumatic stress disorder (PTSD). EMA mo ...
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Journal articleJ Consult Clin Psychol · February 2018
OBJECTIVE: Although research using combat veteran samples has demonstrated an association between posttraumatic stress disorder (PTSD) and violence toward others, there has been relatively little research examining this relationship among individuals with ...
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Journal articlePsychiatry Res · January 2018
Alcohol misuse is associated with negative mental and physical health outcomes, which presents a public health concern in veterans. However, less is known regarding outcomes among veterans with low to moderate alcohol consumption. This study included veter ...
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Journal articleFront Psychiatry · 2018
Posttraumatic stress disorder (PTSD) is a prevalent, chronic disorder with high psychiatric morbidity; however, a substantial portion of affected individuals experience remission after onset. Alterations in brain network topology derived from cortical thic ...
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Journal articleJ Dual Diagn · 2018
OBJECTIVE: The aim of this research was to determine whether augmenting standard smoking cessation treatment by wearing an active nicotine patch before the smoking quit date improves rates of smoking cessation in individuals with posttraumatic stress disor ...
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Journal articleWomens Health Issues · 2018
OBJECTIVES: Prenatal smoking is the leading preventable cause of poor obstetric outcomes, yet treatment options are limited. Past reviews of prenatal smoking cessation have often grouped all counseling into a single category, which ignores the fact that ps ...
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Journal articleEur J Psychotraumatol · 2018
Background: The term resilience is applied in numerous ways in the mental health field, leading to different perspectives of what constitutes a resilient response and disparate findings regarding its prevalence following trauma. Objective: illustrate the i ...
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Journal articleInt J Behav Med · December 2017
PURPOSE: We examined the relation of alcohol consumption to glucose metabolism and insulin resistance (IR) as a function of depressive symptoms, adiposity, and sex. METHOD: Healthy adults (aged 18-65Â years) provided fasting blood samples and information on ...
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Journal articleAm J Med Genet B Neuropsychiatr Genet · December 2017
Suicide is a global public health problem with particular resonance for the US military. Genetic risk factors for suicidality are of interest as indicators of susceptibility and potential targets for intervention. We utilized population-based nonclinical c ...
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Journal articleTransl Psychiatry · November 30, 2017
Depending on the traumatic event, a significant fraction of trauma survivors subsequently develop PTSD. The additional variability in PTSD risk is expected to arise from genetic susceptibility. Unfortunately, several genome-wide association studies (GWAS) ...
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Journal articleGenome Med · November 27, 2017
BACKGROUND: The nature and underlying mechanisms of the observed increased vulnerability to posttraumatic stress disorder (PTSD) in women are unclear. METHODS: We investigated the genetic overlap of PTSD with anthropometric traits and reproductive behavior ...
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Journal articleJ Atten Disord · November 2017
OBJECTIVE: Mindfulness meditation training is garnering increasing empirical interest as an intervention for ADHD in adulthood, although no studies of mindfulness as a standalone treatment have included a sample composed entirely of adults with ADHD or a c ...
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Journal articleRehabil Psychol · November 2017
OBJECTIVE: Sleep disturbance is a key behavioral health concern among Iraq and Afghanistan era veterans and is a frequent complaint among veterans with a history of mild traumatic brain injury (mTBI). Currently, it is unclear whether sleep disturbance is a ...
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Journal articleJ Gen Intern Med · November 2017
BACKGROUND: Research using the Veterans Health Administration (VA) electronic medical records (EMR) has been limited by a lack of reliable smoking data. OBJECTIVE: To evaluate the validity of using VA EMR "Health Factors" data to determine smoking status a ...
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Journal articleJ Affect Disord · October 15, 2017
BACKGROUND: Suicidal ideation (SI) is a serious issue affecting U.S. veterans, and those with posttraumatic stress disorder (PTSD) are at an especially high risk of SI. Guilt has been associated with both PTSD and SI and may therefore be an important link ...
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Journal articleJ Pers · October 2017
OBJECTIVE: Although it is well established that neuroticism increases the risk of posttraumatic stress disorder (PTSD), little is known about the mechanisms that promote PTSD in individuals with elevated levels of neuroticism. Across two studies, we examin ...
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Journal articlePain Med · September 1, 2017
OBJECTIVE: To examine pain symptoms and co-occurring psychiatric and functional indices in male and female Iraq/Afghanistan-era veterans. DESIGN: Self-reported data collection and interviews of Iraq/Afghanistan-era veterans who participated in a multisite ...
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Journal articlePain Med · September 1, 2017
OBJECTIVE: Cigarette smoking and musculoskeletal pain are prevalent among Department of Veterans Affairs (VA) health care system users. These conditions frequently co-occur; however, there is limited empirical information specific to Afghanistan/Iraq era v ...
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Journal articleInt J Methods Psychiatr Res · September 2017
The United States (US) Department of Veterans Affairs (VA) Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC) Post-Deployment Mental Health (PDMH) multi-site study examines post-deployment mental health in US military Afghanistan ...
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Journal articleAm J Med Genet B Neuropsychiatr Genet · September 2017
Compelling evidence suggests that epigenetic mechanisms such as DNA methylation play a role in stress regulation and in the etiologic basis of stress related disorders such as Post traumatic Stress Disorder (PTSD). Here we describe the purpose and methods ...
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Journal articleJ Clin Sleep Med · August 15, 2017
STUDY OBJECTIVES: Insomnia is a widespread issue among United States adults and rates of insomnia among veterans are even higher than the general population. Prior research examining primary care provider (PCP) perspectives on insomnia treatment found that ...
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Journal articleAIDS Behav · July 2017
The Veterans Health Administration is the largest U.S. medical provider for persons living with HIV (PLHIV). Although HIV and veteran status are known risk factors for smoking, there are no population estimates of smoking prevalence among veteran PLHIV. Us ...
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Journal articleJ Psychiatr Res · June 2017
The objective of the present research was to examine the association between lifetime cannabis use disorder (CUD), current suicidal ideation, and lifetime history of suicide attempts in a large and diverse sample of Iraq/Afghanistan-era veterans (NÂ =Â 3233) ...
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Journal articlePsychiatry Res · June 2017
The objective of the present research was to examine the association between ADHD symptoms and nonsuicidal self-injury (NSSI) in male Iraq/Afghanistan-era veterans with and without PTSD. Approximately 25% of veterans screened positive for clinically-signif ...
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Journal articlePsychosom Med · June 2017
OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to elevated heart rate (HR) and reduced heart rate variability (HRV) in cross-sectional research. Recent evidence suggests that this link may be driven by individual differences in autonomic a ...
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Journal articleAnxiety Stress Coping · March 2017
BACKGROUND AND OBJECTIVES: Involvement in wartime combat often conveys a number of deleterious outcomes, including posttraumatic stress disorder (PTSD), depression, hostility, aggression, and suicidal ideation. Less studied is the effect of engagement in w ...
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Journal articleJ Abnorm Psychol · February 2017
This research sought to determine whether smoking influences affect by means other than withdrawal reduction. Little previous evidence suggests such an effect. We surmised that such an effect would be especially apparent in posttraumatic stress disorder (P ...
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Journal articleJ Psychiatr Res · January 2017
The aim of the present study was to attempt to replicate the recently reported finding associating rs2400707 of the Adrenoceptor Beta 2, Surface (ADRB2) gene and childhood trauma on PTSD symptoms. Participants included a predominantly veteran cohort of non ...
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Journal articlePsychiatry Res · January 2017
Nonsuicidal self-injury (NSSI) has been defined as deliberately damaging one's body tissue without conscious suicidal intent. NSSI is a robust predictor of suicidal ideation and attempts in adults. While NSSI has been associated with other-directed violenc ...
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Journal articleJ Dual Diagn · 2017
OBJECTIVES: Smokers with posttraumatic stress disorder (PTSD) have increased difficulty achieving and maintaining abstinence. Contingency management approaches to smoking cessation interventions have demonstrated short-term efficacy but are limited by high ...
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Journal articleBehav Brain Sci · January 2017
In this commentary, we contest Van Lange and colleagues' central claim that "countries closer to the equator are generally more violent." We point to the lack of credible empirical evidence for this assertion and suggest that the CLASH model uses the langu ...
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Journal articlePsychosom Med · December 9, 2016
OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to elevated heart rate (HR) and reduced heart-rate variability (HRV) in cross-sectional research. Recent evidence suggests that this link may be driven by individual differences in autonomic a ...
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Journal articleAddict Behav · November 2016
BACKGROUND: SmokefreeVET is a text messaging smoking cessation program available to veterans enrolled in the Veterans Health Administration. SmokefreeVET was developed in collaboration with the National Cancer Institute as part of the SmokefreeTXT initiati ...
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Journal articleJ Subst Abuse Treat · October 2016
INTRODUCTION: The primary objective of this project was to examine the effectiveness of an Internet-based smoking cessation intervention combined with a tele-health medication clinic for nicotine replacement therapy (NRT) compared to referral to clinic-bas ...
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Journal articleJ Trauma Stress · October 2016
Prior research has demonstrated that individuals exposed to trauma have shown impaired autonomic function. We sought to determine if heart rate variability (HRV), a marker of impaired autonomic function, differed across periods of wake, rest, and sleep as ...
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Journal articleJ Abnorm Psychol · October 2016
We find Brewin's (2016) critiques of the narratives, power, and coherence measures in Rubin et al. (2016) without merit; his suggestions for a "revised formulation" (p. 1015) of coherence are contradicted by data readily available in the target article but ...
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Journal articleMent Health Phys Act · October 2016
UNLABELLED: Individuals with posttraumatic stress disorder (PTSD) have elevated rates of morbidity, and a sedentary lifestyle can cause and aggravate the physical health needs of adults with PTSD. The primary aim of this paper was to explore the impact of ...
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Journal articleJ Racial Ethn Health Disparities · September 15, 2016
INTRODUCTION: Access to the internet at home may be an important barrier to electronic health (eHealth) smoking cessation interventions. The current study explored possible sociodemographic disparities in access to the internet at home among veteran smoker ...
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Journal articlePsychosom Med · September 2016
OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to elevated heart rate (HR) and reduced heart rate variability (HRV) in cross-sectional research. Using ecological momentary assessment and minute-to-minute HRV/HR monitoring, we examined whet ...
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Journal articleAddict Behav · September 2016
Existing models of the role of posttraumatic stress disorder (PTSD) symptoms and smoking have almost exclusively examined mean symptom levels, rather than the acute elevations that might trigger smoking lapse immediately or increase risk of a smoking lapse ...
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Journal articleContemp Clin Trials · September 2016
INTRODUCTION: Smoking is the most preventable cause of morbidity and mortality in U.S. veterans. Rural veterans in particular have elevated risk for smoking and smoking-related illness. However, these veterans underutilize smoking cessation treatment, whic ...
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Journal articleAddict Behav · August 2016
BACKGROUND: Individuals with posttraumatic stress disorder (PTSD) are more likely to smoke and more likely to relapse following a quit attempt than individuals without PTSD. Thus, there is a significant need to study promising interventions that might impr ...
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Journal articlePsychiatry Res · June 30, 2016
Research in both civilian and military populations has demonstrated that females who experience childhood sexual abuse (CSA) are more likely to experience sexual assault in adulthood than females who did not experience CSA. Among veteran samples, however, ...
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Journal articleAm J Respir Crit Care Med · June 15, 2016
RATIONALE: The incidence and risk factors of post-traumatic stress disorder (PTSD) related to the intensive care unit (ICU) experience have not been reported in a mixed veteran and civilian cohort. OBJECTIVES: To describe the incidence and risk factors for ...
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Journal articleAm J Drug Alcohol Abuse · May 2016
BACKGROUND: Binge drinking is a significant public health concern linked to a number of health and psychosocial problems. Military service in Afghanistan (OEF) and Iraq (OIF) has been associated with posttraumatic stress disorder (PTSD) and increased hazar ...
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Journal articlePsychol Addict Behav · May 2016
Recent research has documented high rates of comorbidity between cannabis use disorders and posttraumatic stress disorder (PTSD) in veterans. However, despite possible links between PTSD and cannabis use, relatively little is known about cannabis use in ve ...
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Journal articleJ Psychosom Res · April 2016
OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to chronic inflammation, a condition that poses a risk for cardiovascular disease. Attenuated vagal activity has been proposed as a potential mediator of PTSD and inflammation, although associ ...
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Journal articlePsychol Trauma · March 2016
Subthreshold posttraumatic stress disorder (PTSD) is a chronic condition that is often ignored, the cumulative effects of which can negatively impact an individual's quality of life and overall health care costs. However, subthreshold PTSD prevalence rates ...
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Journal articleJ Psychosom Res · March 2016
OBJECTIVE: Exposure to trauma-related cues has been associated with a prolonged decrease in heart rate variability (HRV) under laboratory conditions, however the relationship between PTSD symptoms and HRV has not been evaluated during everyday life. The pr ...
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Journal articlePain Med · January 2016
BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans, many of whom continue to experience persistent pain symptoms despite multiple pharmacological interventions. Preclinical data suggest that neurosteroids such as allopr ...
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Journal articleBehav Ther · January 2016
Posttraumatic stress disorder (PTSD) and smoking are often comorbid, and both problems are in need of improved access to evidence-based treatment. The combined approach could address two high-priority problems and increase patient access to both treatments ...
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Journal articleJ Abnorm Psychol · January 2016
We examined the coherence of trauma memories in a trauma-exposed community sample of 30 adults with and 30 without posttraumatic stress disorder. The groups had similar categories of traumas and were matched on multiple factors that could affect the cohere ...
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Journal articlePsychiatry · 2016
OBJECTIVE: Most veterans with posttraumatic stress disorder (PTSD) are not violent, yet research has demonstrated that there is a substantial minority who are at increased risk. This study tested hypotheses regarding hyperarousal symptoms and hostile cogni ...
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Book section · January 1, 2016
The present study assessed drug use and the validity of self-reports of substance use among help-seeking veterans referred to a specialty clinic for the assessment of posttraumatic stress disorder (PTSD). Patients (n = 341) were asked to provide a urine sa ...
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Journal articleTransl Psychiatry · December 15, 2015
Fear conditioning is an established model for investigating posttraumatic stress disorder (PTSD). However, symptom triggers may vaguely resemble the initial traumatic event, differing on a variety of sensory and affective dimensions. We extended the fear-c ...
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Journal articlePsychol Serv · November 2015
Despite research findings that similar numbers of male and female veterans are affected by military sexual trauma (MST), there has been considerably less research on the effects of MST specific to male veterans. The aim of the present study was to provide ...
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Journal articleJ Psychopharmacol · October 2015
Most smokers who attempt to quit lapse within the first week and are ultimately unsuccessful in their quit attempt. Nicotine withdrawal exacerbates cognitive and attentional problems and may be one factor in smoking relapse. The startle reflex response and ...
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Journal articlePsychiatry Res · September 30, 2015
The present study examined the association between genetic variation in the nicotinic receptor gene family (CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNA10, CHRNB2, CHRNB3, CHRNB4) and the occurrence of posttraumatic stress disorder (PTSD). ...
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Journal articleJ Clin Sleep Med · September 15, 2015
STUDY OBJECTIVES: Sleep disturbance is among the most common complaints of veterans and military personnel who deployed to the conflicts in Iraq and Afghanistan. A growing body of research has examined cross-sectional and longitudinal relationships between ...
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Journal articleJ Affect Disord · September 15, 2015
BACKGROUND: Posttraumatic stress disorder (PTSD) is a psychiatric disorder that can develop after experiencing traumatic events. A genome-wide association study (GWAS) design was used to identify genetic risk factors for PTSD within a multi-racial sample p ...
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Journal articleJ Clin Psychiatry · July 2015
INTRODUCTION: Smoking rates are 80% among persons who are homeless, and these smokers have decreased odds of quitting smoking. Little is known about relapse rates among homeless smokers. More information is needed regarding both quit rates and innovative m ...
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Journal articleDrug Alcohol Depend · July 1, 2015
BACKGROUND: The current study was undertaken to examine whether posttraumatic stress symptoms (PTSS) and depressive symptoms mediated the association between trauma exposure (combat-related trauma and non-combat traumas occurring before, during, and after ...
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Journal articlePsychiatry Res · June 30, 2015
The present study examined the association between lifetime non-suicidal self-injury (NSSI) and current suicidal ideation among Iraq/Afghanistan veterans. NSSI was positively associated with passive, active, and concurrent active-passive suicidal ideation ...
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Journal articleJ Behav Med · June 2015
Recent evidence suggests that sleep disturbance may play an important role in the development of cardiovascular disease (CVD). Despite the prevalence of sleep complaints among service members of recent military conflicts, few studies have examined associat ...
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Journal articlePsychol Trauma · May 2015
The purpose of this research is (a) to evaluate differences in orthostatic hypotension (OH) among young adults with and without posttraumatic stress disorder (PTSD) and (b) to examine whether group differences may be attributable to behavioral risk factors ...
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Journal articleDepress Anxiety · May 2015
BACKGROUND: The apolipoprotein E (APOE) ε4 allele has been implicated in a range of neuropsychiatric conditions. The present research examined if the ε4 allele of the APOE gene moderated the effect of combat exposure on posttraumatic stress disorder (PTSD) ...
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Journal articleJ Anxiety Disord · April 2015
Literature on posttraumatic stress disorder (PTSD) prevalence among Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) veterans report estimates ranging from 1.4% to 60%. A more precise estimate is necessary for projecting healthcare needs and informi ...
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Journal articlePsychiatry Res · March 30, 2015
The objective of the present research was to test the hypotheses that: (1) Iraq/Afghanistan war veterans experience a wide range of psychiatric symptomatology (e.g., obsessive-compulsive symptoms, hypochondriasis, somatization); and (2) general psychiatric ...
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Journal articleAddict Behav · March 2015
South Africa has high rates of interpersonal violence and a rapidly growing methamphetamine epidemic. Previous research has linked experiences of interpersonal violence to higher rates of substance use, and identified mental health constructs as potential ...
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Journal articleAddict Behav · February 2015
INTRODUCTION: This study identified distinct tobacco use trajectories across 18months in 943 veteran smokers with posttraumatic stress disorder (PTSD) in order to describe quit and relapse patterns, examine associations between trajectory groups on baselin ...
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Journal articleAnxiety Stress Coping · 2015
BACKGROUND AND OBJECTIVES: Posttraumatic stress disorder (PTSD), depression, anxiety, and stress are significant problems among returning veterans and are associated with reduced quality of life. DESIGN: A correlational design was used to examine the impac ...
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Journal articlePLoS One · 2015
OBJECTIVE: To examine the association between the 5-HTTLPR polymorphism of the serotonin transporter (SLC6A4) gene, combat exposure, and posttraumatic stress disorder (PTSD) diagnosis and among two samples of combat-exposed veterans. METHOD: The first samp ...
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Journal articleBehav Brain Sci · 2015
Lane et al.'s proposal that psychotherapeutic change comes about through memory reconsolidation is compelling; however, the model would be strengthened by the inclusion of predictions regarding additional factors that might influence treatment response, pr ...
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Journal articlePsychopathol Rev · 2015
The current study examined the latent factor structure of posttraumatic stress disorder (PTSD) based on DSM-5 criteria in a sample of participants (N = 374) recruited for studies on trauma and health. Confirmatory factor analyses (CFA) were used to compare ...
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Journal articlePsychosomatics · 2015
BACKGROUND: Although a large body of literature has linked posttraumatic stress disorder (PTSD) with poor physical health among older veterans, less is known regarding the association between PTSD and health among relatively younger cohorts of veterans. OB ...
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Journal articleBehav Brain Sci · 2015
The authors' definition of resilience is too narrow and essentially defines resilience as the absence of psychopathology. Consequently, it is not clear how quantitatively defined resilience differs from quantitatively defined psychopathology according to t ...
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Journal articlePsychiatry Res · December 15, 2014
The present research examined how incarceration, suicide attempts, suicidality, and difficulty controlling violence relate to the underlying factor structure of psychiatric comorbidity among a large sample of Iraq/Afghanistan-era veterans (N=1897). Diagnos ...
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Journal articleJ Psychiatr Res · December 2014
Posttraumatic stress disorder (PTSD) is a significant problem among Iraq/Afghanistan-era veterans. To date, however, there has been only limited research on how the recent changes in DSM-5 influence the prevalence and factor structure of PTSD. To address t ...
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Journal articlePsychosom Med · October 2014
OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to reduced heart rate variability (HRV), which is in turn a risk factor for cardiovascular disease and death. Although hyperarousal and anxiety are thought to underlie this association, behavi ...
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Journal articleAm J Public Health · October 2014
OBJECTIVES: We evaluated the feasibility of incorporating integrated care (IC) for smoking cessation into routine treatment for posttraumatic stress disorder (PTSD) at Department of Veterans Affairs (VA) Medical Centers and the utility of the Learning Coll ...
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Journal articleSubst Use Misuse · September 2014
The current study assessed antecedents and consequences of ad lib cigarette smoking in smokers diagnosed with attention-deficit/hyperactivity disorder (ADHD) using ecological momentary assessment (EMA). Adult smokers with ADHD (n = 17) completed 870 smokin ...
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Journal articleAssessment · August 2014
The present study examined the structural validity of the 25-item Connor-Davidson Resilience Scale (CD-RISC) in a large sample of U.S. veterans with military service since September 11, 2001. Participants (N = 1,981) completed the 25-item CD-RISC, a struct ...
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Journal articlePsychol Serv · August 2014
As a result of their military experience, veterans with mental health problems may have unique motivations for seeking help from clergy. Patterns and correlates of seeking pastoral care were examined using a nationwide representative survey that was conduc ...
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Journal articleJ Trauma Stress · August 2014
The objectives of the present research were to examine the prevalence of deliberate self-harm (DSH) among 214 U.S. male Iraq/Afghanistan-era veterans seeking treatment for posttraumatic stress disorder (PTSD) and to evaluate the relationship between DSH an ...
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Journal articleAddict Behav · July 2014
BACKGROUND: Following a smoking cessation attempt, smokers with posttraumatic stress disorder (PTSD) experience smoking relapse at a higher and faster rate. Black ethnicity and female gender are also associated with lower success rates following smoking ce ...
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Journal articleAm J Psychiatry · July 2014
OBJECTIVE: Violence toward others is a serious problem among a subset of military veterans. The authors evaluated the predictive validity of a brief decision support tool to screen veterans for problems with violence and identify potential candidates for a ...
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Journal articleJ Psychosom Res · July 2014
OBJECTIVES: Posttraumatic stress disorder (PTSD) has been linked to dyslipidemia, which is a major risk factor for coronary artery disease. Although this link is thought to reflect response to heightened stress, behavioral health risks, including smoking, ...
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Journal articlePsychiatry Res · June 30, 2014
This study aimed to examine the degree to which posttraumatic stress disorder (PTSD) affects the relationship between social support and psychological distress for U.S. Afghanistan/Iraq era veterans with and without co-occurring psychiatric disorders. Vete ...
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Journal articleNicotine Tob Res · June 2014
INTRODUCTION: Ecological momentary assessment (EMA) has shown that smoking behavior is linked to transient variables in the smoker's immediate context. Such research suggests that daily hassles (e.g., losing one's keys) may be more likely to lead to cigare ...
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Journal articlePsychol Serv · May 2014
Although a subset of Iraq and Afghanistan Veterans show aggression toward others after they return home from military service, little is known about protective mechanisms that could be bolstered to prevent violence. A national longitudinal survey was condu ...
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Journal articleMil Med · May 2014
Cigarette smoking disproportionately affects veterans, particularly those with psychiatric diagnoses. Chaplains working within the Department of Veterans Affairs (VA) play key roles in emotional, physical, and spiritual health care of veterans, and veteran ...
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Journal articleMil Med · May 2014
Veteran populations are exposed to multiple stressful events, and suicidality among veterans is a serious problem. Identifying biomarkers of suicidality may enhance detection, prevention, and treatment. Multiple neurotransmitter systems are implicated in t ...
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Journal articleNicotine Tob Res · April 2014
INTRODUCTION: Smokers with posttraumatic stress disorder (PTSD) tend to lapse more quickly following a quit attempt, which might be explained by changes in PTSD symptoms during a quit attempt. The present study examines changes in PTSD symptoms, negative a ...
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Journal articleAddict Behav · February 2014
OBJECTIVE: The present study sought to investigate the longitudinal effects of psychological resilience against alcohol misuse adjusting for socio-demographic factors, trauma-related variables, and self-reported history of alcohol abuse. METHODOLOGY: Data ...
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Journal articleBr J Psychiatry · 2014
BACKGROUND: Violence towards others in the community has been identified as a significant problem for a subset of Iraq and Afghanistan veterans. AIMS: To investigate the extent to which post-traumatic stress disorder (PTSD) and other risk factors predict f ...
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Journal articleJ Dual Diagn · 2014
OBJECTIVE: Ecological momentary assessment (EMA) methods have provided a rich assessment of the contextual factors associated with a wide range of behaviors including alcohol use, eating, physical activity, and smoking. Despite this rich database, this inf ...
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Journal articleJ Rehabil Res Dev · 2014
This study examines the effect of posttraumatic stress disorder (PTSD) on function and physical performance in older overweight military Veterans with comorbid conditions. This is a secondary data analysis of older Veterans (mean age = 62.9 yr) participati ...
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Journal articleAggress Behav · 2014
Posttraumatic stress disorder (PTSD) is associated with aggressive behavior in veterans, and difficulty controlling aggressive urges has been identified as a primary postdeployment readjustment concern. Yet only a fraction of veterans with PTSD commit viol ...
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Journal articleWomens Health Issues · 2014
BACKGROUND: Given recent, rapid growth in the field of women veterans' mental health, the goal of this review was to update the status of women veterans' mental health research and to identify current themes in this literature. The scope of this review inc ...
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Journal articleJ Addict Dis · 2014
Cognitive-affective mechanisms related to the maintenance of smoking among trauma-exposed individuals are largely unknown. Cross-sectional data from trauma-exposed treatment-seeking smokers (n = 283) were utilized to test a series of multiple mediator mode ...
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Journal articleInt Clin Psychopharmacol · January 2014
There has been a great deal of interest in the role of the neuroendocrine hormones of the hypothalamic-pituitary-adrenal (HPA) axis in the expression of stress-related psychopathology such as post-traumatic stress disorder (PTSD). This investigation examin ...
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Journal articleNeuropsychopharmacology · January 2014
The amygdala is a major structure that orchestrates defensive reactions to environmental threats and is implicated in hypervigilance and symptoms of heightened arousal in posttraumatic stress disorder (PTSD). The basolateral and centromedial amygdala (CMA) ...
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Journal articlePsychol Addict Behav · December 2013
The risk of smoking increases with specific psychiatric diagnoses (e.g., posttraumatic stress disorder); but the risk has also been shown to increase as a function of the number of psychiatric illnesses with which a person is diagnosed. The current study e ...
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Journal articlePsychopharmacology (Berl) · December 2013
RATIONALE: Cigarette smokers smoke in part because nicotine helps regulate attention. Prepulse inhibition (PPI) of the startle reflex is a measure of early attentional gating that is reduced in abstinent smokers and in groups with attention regulation diff ...
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Journal articleAm J Public Health · December 2013
OBJECTIVES: We examined the empirical link between money mismanagement and subsequent homelessness among veterans. METHODS: We used a random sample of Iraq and Afghanistan War era veterans from the National Post-Deployment Adjustment Survey in 2009-2011. R ...
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Journal articleHum Brain Mapp · November 2013
Mild traumatic brain injury (TBI) is a common source of morbidity from the wars in Iraq and Afghanistan. With no overt lesions on structural MRI, diagnosis of chronic mild TBI in military veterans relies on obtaining an accurate history and assessment of b ...
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Journal articleNicotine Tob Res · November 2013
INTRODUCTION: Smokers with posttraumatic stress disorder (PTSD) smoke at higher prevalence rates and are more likely to relapse early in a quit attempt. Innovative methods are needed to enhance quit rates, particularly in the early quit period. Web-based c ...
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Journal articlePain Med · October 2013
OBJECTIVE: Research has shown significant rates of comorbidity among posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and pain in prior era veterans but less is known about these disorders in Iraq and Afghanistan war era veterans. Thi ...
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Journal articleJ Nerv Ment Dis · October 2013
This study, using a longitudinal design, attempted to identify whether self-reported problems with violence were empirically associated with future violent behavior among Iraq and Afghanistan war veterans and whether and how collateral informant interviews ...
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Journal articleDrug Alcohol Depend · September 1, 2013
BACKGROUND: Alcohol screening with the 3-item alcohol use disorders identification test (AUDIT-C) has been implemented throughout the U.S. Veterans Health Administration. Validation of the AUDIT-C, however, has been conducted with samples of primarily olde ...
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Journal articleJ Clin Psychopharmacol · August 2013
Posttraumatic stress disorder (PTSD) is associated with increased smoking initiation, maintenance, and relapse. Dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) are neurosteroids that have been associated with mood measures as well as smoking status, ...
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Journal articleSleep · July 1, 2013
STUDY OBJECTIVES: Short and long sleep duration have been linked with higher rates of comorbid medical and mental health issues, as well as increased mortality. The current study examined the association between sleep duration, mental health problems, and ...
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Journal articleJ Depress Anxiety · June 1, 2013
BACKGOUND: Posttraumatic stress sisorder (PTSD) is a complex anxiety disorder that can develop after traumatic event exposure. Genetic factors have been associated with PTSD risk. Recently a variant rs4790904 in the protein kinase C alpha (PRKCA) gene has ...
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Journal articleNicotine Tob Res · June 2013
INTRODUCTION: Retrospective research suggests smokers with posttraumatic stress disorder (PTSD) lapse more quickly after their quit date. Ecological momentary assessment (EMA) research is needed to confirm the presence of early smoking lapse in PTSD and fo ...
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Journal articleJ Clin Psychol Med Settings · March 2013
The literature on PTSD and metabolic disease risk factors has been limited by lacking investigation of the potential influence of commonly comorbid disorders and the role of race. In this study data were provided by a sample of 134 women (63 PTSD and 71 wi ...
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Journal articlePsychol Addict Behav · March 2013
A survey was administered anonymously to 45 mental health providers who delivered smoking cessation treatment integrated into posttraumatic stress disorder care (integrated care) as part of a multisite clinical trial. Survey items assessed key factors asso ...
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Journal articleAnn Clin Psychiatry · February 2013
BACKGROUND: This study prospectively evaluated the correlation and role of resilience and resilience factors in predicting suicidal ideation and attempts in veterans. METHODS: In this 3-year longitudinal study, 178 Iraq and Afghanistan war veterans were ev ...
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Journal articlePsychiatr Serv · February 1, 2013
OBJECTIVE: This study analyzed data from a national survey of Iraq and Afghanistan veterans to improve understanding of mental health services use and perceived barriers. METHODS: The National Post-Deployment Adjustment Survey randomly sampled post-9/11 ve ...
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Journal articleBehav Med · 2013
Women with posttraumatic stress disorder (PTSD) have poor sleep quality and increased risk of cardiovascular disease (CVD). Non-dipping of nocturnal blood pressure may be an explanatory factor for the relationship between sleep and CVD found in previous re ...
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Journal articleArch Suicide Res · 2013
This study evaluated the effect of childhood trauma exposure and the role of resilience on both depressive symptoms and suicidal ideation. The study evaluated 1,488 military personnel and veterans, who served after September 2001, for depressive, suicidal, ...
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Journal articleDepress Anxiety · December 2012
BACKGROUND: This study was designed to examine the concordance of proposed DSM-V posttraumatic stress disorder (PTSD) criteria with DSM-IV classification rules and examine the impact of the proposed DSM-V PTSD criteria on prevalence. METHOD: The sample (N ...
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Journal articleJ Consult Clin Psychol · December 2012
OBJECTIVE: Although criminal behavior in veterans has been cited as a growing problem, little is known about why some veterans are at increased risk for arrest. Theories of criminal behavior postulate that people who have been exposed to stressful environm ...
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Journal articleJ Trauma Stress · October 2012
Major depressive disorder (MDD) co-occurs frequently with posttraumatic stress disorder (PTSD), and both disorders are linked to suicidal ideation. An emergent literature examines suicidal ideation in U.S. Afghanistan/Iraq-era veterans. Little research, ho ...
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Journal articleGenet Test Mol Biomarkers · September 2012
The perspectives of patients with posttraumatic stress disorder (PTSD) on genetic research have not yet been investigated in the genetics research literature. To provide a basis for research on attitudes toward genetic research in PTSD, we surveyed the U.S ...
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Journal articleNicotine Tob Res · August 2012
INTRODUCTION: Smoking outcome expectancies were investigated in treatment-seeking military Veteran smokers with posttraumatic stress disorder (PTSD). The investigation of smoking outcome expectancies may enhance our understanding of the relationship betwee ...
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Journal articleNicotine Tob Res · August 2012
INTRODUCTION: Smoking prevalence among individuals with posttraumatic stress disorder (PTSD) is elevated relative to non-PTSD smokers, and there is evidence to suggest that affect regulation may be a motivation for smoking among those with this disorder. P ...
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Journal articleJ Clin Psychiatry · June 2012
OBJECTIVE: After returning home, a subset of Iraq and Afghanistan War veterans report engaging in aggression toward others. This study is the first to identify variables empirically related to decreased risk of community violence among veterans. METHOD: Th ...
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Journal articleMil Med · June 2012
Research has yet to examine the relationship between financial well-being and community reintegration of veterans. To address this, we analyzed data from n = 1,388 Iraq and Afghanistan War Era Veterans who completed a national survey on postdeployment adju ...
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Journal articleChild Abuse Negl · May 2012
OBJECTIVE: This study examined the relationship among childhood trauma, posttraumatic stress disorder (PTSD) symptoms, and adult social support in a large sample of veterans who served in the military after 09/11/2001, with a specific focus on the potentia ...
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Journal articleMed Hypotheses · May 2012
Both females and individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) have been found to be at increased risk for a range of smoking outcomes, and recent empirical findings have suggested that women with ADHD may be particularly vulnerable to n ...
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Journal articleNicotine Tob Res · March 2012
INTRODUCTION: Previous research on smoking withdrawal in posttraumatic stress disorder (PTSD) has been limited by the use of retrospective and observational methods and has lacked repeated assessments on the first day of abstinence and evaluation of the co ...
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Journal articleJ Trauma Stress · February 2012
Smoking prevalence among patients with posttraumatic stress disorder (PTSD) is over 40%. Baseline data from the VA Cooperative Studies Program trial of integrated versus usual care for smoking cessation in veterans with PTSD (N = 863) were used in multivar ...
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Journal articlePrev Chronic Dis · 2012
INTRODUCTION: Military service and combat exposure are risk factors for smoking. Although evidence suggests that veterans are interested in tobacco use cessation, little is known about their reasons for quitting, treatment preferences, and perceived barrie ...
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Journal articleViolence Vict · 2012
Research has documented significant relationships between posttraumatic stress disorder (PTSD), aggression, and intimate partner violence (IPV). Most of these studies have focused on men and measured violence by self-report. This study examined (a) the ass ...
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Journal articleAdv Pharmacol Sci · 2012
There is evidence that individuals with posttraumatic stress disorder (PTSD) may smoke in part to regulate negative affect. This pilot fMRI study examined the effects of nicotine on emotional information processing in smokers with and without PTSD. Across ...
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Journal articleConscious Cogn · September 2011
To provide the three-way comparisons needed to test existing theories, we compared (1) most-stressful memories to other memories and (2) involuntary to voluntary memories (3) in 75 community dwelling adults with and 42 without a current diagnosis of posttr ...
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Journal articleJ Trauma Stress · June 2011
Posttraumatic stress disorder (PTSD) is associated with increased rates of smoking although little is known regarding the mechanisms underlying this relationship. The current study examined expectations about smoking outcomes among smokers with and without ...
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Journal articlePsychopharmacology (Berl) · May 2011
RATIONALE: Exaggerated startle response is a prominent feature of posttraumatic stress disorder (PTSD) although results examining differences in the acoustic startle response (ASR) between those with and without PTSD are mixed. One variable that may affect ...
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Journal articleMilitary Psychology · May 1, 2011
Little is known about the smoking habits and cessation efforts of veterans returning from Iraq and Afghanistan, many of whom will seek health care services in the public sector. This project documents rates of smoking and quit attempts among veterans recei ...
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Journal articleJ Addict Med · March 2011
OBJECTIVE: The purpose of this clinical demonstration project was to increase the reach of effective treatments, such as pharmacotherapy and telephone or web-based support, by offering these treatments in a low cost and convenient manner to a population of ...
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Book section · January 1, 2011
Posttraumatic stress disorder (PTSD) is common in the general population with estimates ranging from 7% to 9% (Kessler et al., 1995; Breslau et al., 1998) and is even more prevalent among patients presenting to primary care settings, where rates range from ...
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Journal articleJAMA · December 8, 2010
CONTEXT: Most smokers with mental illness do not receive tobacco cessation treatment. OBJECTIVE: To determine whether integrating smoking cessation treatment into mental health care for veterans with posttraumatic stress disorder (PTSD) improves long-term ...
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Journal articleJ Trauma Stress · December 2010
In this study, symptoms of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) were modeled as intervening variables in the relationship between childhood traumatic stress and weight outcomes in civilian women in the United States. Of ...
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Journal articleNicotine Tob Res · November 2010
INTRODUCTION: The present investigation examined the main and interactive effects of posttraumatic stress symptom severity and 12-hr cigarette deprivation (cf. smoking as usual) in the prediction of anxious responding during a 4-min 10% carbon dioxide (COâ‚‚ ...
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Journal articleAm J Psychiatry · September 2010
OBJECTIVE: As troops return from Iraq and Afghanistan to civilian life, clinicians are starting to grapple with how best to detect those at risk of postdeployment adjustment problems. Data reveal the presence of mental health problems in these soldiers, in ...
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Journal articleClin Psychol Rev · August 2010
Increased media attention to post-deployment violence highlights the need to develop effective models to guide risk assessment among military Veterans. Ideally, a method would help identify which Veterans are most at risk for violence so that it can be det ...
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Journal articlePsychiatry Res · July 30, 2010
Posttraumatic stress disorder (PTSD) is a prevalent anxiety disorder that is often undetected among primary care patients. The Department of Veterans Affairs has implemented the Primary Care-PTSD Screen (PC-PTSD) to screen for PTSD; however, minimal resear ...
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Journal articleJ Clin Psychiatry · July 2010
OBJECTIVE: This study evaluated the relationship between resilience and psychological functioning in military veterans deployed to a region of military conflict in support of Operation Enduring Freedom or Operation Iraqi Freedom. METHOD: 497 military veter ...
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Journal articleAnn Behav Med · February 2010
BACKGROUND: Posttraumatic stress disorder (PTSD) is a significant risk factor for cardiovascular and metabolic disease. PURPOSE: The purpose of the current review is to evaluate the evidence suggesting that PTSD increases cardiovascular and metabolic risk ...
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Journal articleAddict Behav · January 2010
Veterans with posttraumatic stress disorder are at high risk for smoking and experience difficulty with smoking cessation. We designed this clinical demonstration project to provide a low-cost, feasibly implemented smoking cessation intervention that would ...
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Journal articleCompr Psychiatry · 2010
Posttraumatic stress disorder (PTSD) can be a complex disorder, and some studies have found that samples of individuals with PTSD contain subtypes that may relate to health outcomes. The goals were to replicate previously identified PTSD subtypes and exami ...
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Journal articleJ Trauma Stress · December 2009
In a previous study, women with posttraumatic stress disorder (PTSD) had greater objective sleep disturbance than those without PTSD. In a separate previous study, women with PTSD were also found to have lower baroreceptor sensitivity (BRS), an index of bl ...
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Journal articleBiol Psychol · December 2009
Previous literature has found greater heart rate (HR) and blood pressure (BP) responses during relived anger, and a positive association between covert hostility and relived anger, in male veterans with posttraumatic stress disorder (PTSD). This study inve ...
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Journal articleJ Pers Assess · September 2009
In this study, we examined the diagnostic efficiency of the Personality Assessment Inventory (PAI; Morey, 1991) for the assessment of posttraumatic stress disorder (PTSD) in a community-based sample of women (n = 128). Receiver operating characteristic cur ...
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Journal articleJ Trauma Stress · August 2009
The authors investigated the relationship between childhood abuse and obesity in young adulthood (M age = 22) in a large, U.S. representative sample (N = 15,197). Controlling for demographics and depression, men with a history of childhood sexual abuse wer ...
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Journal articleJ Psychiatr Res · June 2009
OBJECTIVE: This study examined the association of lifetime traumatic stress with psychiatric diagnostic status and symptom severity in veterans serving in the US military after 9/11/01. METHOD: Data from 356 US military veterans were analyzed. Measures inc ...
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Journal articleViolence Against Women · May 2009
The current study examines lifetime trauma exposure rates in 148 women with posttraumatic stress disorder (PTSD), major depressive disorder (MDD), or neither diagnosis and whether this is related to measures of PTSD, depression, hostility, health symptoms, ...
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Journal articleJ Trauma Stress · April 2009
Posttraumatic stress disorder has been associated with poor physical health. Depression is also associated with poor health, and may be responsible for the apparent relationship between PTSD and health outcomes. The current study examined self-reported and ...
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Journal articleJ Anxiety Disord · March 2009
The present study examined the psychometric properties and diagnostic efficiency of the Davidson Trauma Scale (DTS), a self-report measure of posttraumatic stress disorder (PTSD) symptoms. Participants included 158 U.S. military veterans who have served si ...
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Journal articleBiol Psychiatry · February 1, 2009
BACKGROUND: The objective of the current study is to evaluate the relationship between hostility and ambulatory cardiovascular activity in women with and without posttraumatic stress disorder (PTSD). METHODS: One hundred and one women completed 24 hours of ...
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Journal articleJ Psychopathol Behav Assess · January 1, 2009
The present study describes Personality Assessment Inventory (PAI) profiles for women with posttraumatic stress disorder (PTSD). Four groups of women were sampled: single Axis I diagnosis of PTSD; PTSD and major depressive disorder (MDD); PTSD, MDD, at lea ...
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Journal articleNicotine Tob Res · December 2008
The National Institute of Mental Health (NIMH) convened a meeting in September 2005 to review tobacco use and dependence and smoking cessation among those with mental disorders, especially individuals with anxiety disorders, depression, or schizophrenia. S ...
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Journal articleAddict Behav · November 2008
Past research has shown that veterans and individuals with posttraumatic stress disorder (PTSD) have increased rates of smoking. However, the rates of smoking in younger help-seeking veterans returning from Afghanistan and Iraq, and possible correlates of ...
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Journal article · August 8, 2008
This chapter outlines the clinical presentation of posttraumatic stress disorder and acute stress disorder, two anxiety disorders that may emerge following exposure to traumatic life events (eg., combat, sexual assault, physical assault, natural disasters) ...
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Journal articleNicotine Tob Res · July 2008
Using ambulatory methods for 1 week of monitoring, this study investigated the association between smoking and situational cues in 22 smokers with post-traumatic stress disorder (PTSD) and 23 smokers without PTSD. Generalized estimating equations contraste ...
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Journal articleJ Trauma Stress · June 2008
Research generally supports a 4-factor structure of posttraumatic stress disorder (PTSD) symptoms. However, few studies have established factor invariance by comparing multiple groups. This study examined PTSD symptom structure using the Davidson Trauma Sc ...
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Journal articleJ Psychiatr Res · May 2008
Self-mutilative behaviors (SMB) were examined in a sample of male veterans with posttraumatic stress disorder (PTSD). The primary objective was to determine the prevalence of SMB and any physical, cognitive, or affective antecedents and correlates for thes ...
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Journal articleMil Med · May 2008
Military veterans are at high risk for nicotine dependence. This clinical demonstration project used invitational letters, referral to the National Cancer Institute's Smoking Quitline, and local Veteran Affairs prescriptions for tobacco cessation to evalua ...
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Journal articleJ Adolesc Health · March 2008
PURPOSE: To evaluate the relation between smoking and trauma exposure in a population-based, longitudinal sample. Contrary to current smoking trends in the general population, recent findings indicate continued high smoking rates in trauma-exposed samples. ...
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Journal articleJ Trauma Stress · February 2008
Although empirical research has examined factors associated with increased violence risk among individuals with severe mental illness (SMI) and among veterans without SMI, less attention has been devoted to identifying violence risk factors among veterans ...
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Journal articleAddict Behav · December 2007
The study investigated the effects of smoking a nicotinized or denicotinized cigarette on craving, affect and posttraumatic stress disorder (PTSD) symptoms while recalling neutral, stressful and traumatic events in smokers with and without PTSD. Smokers co ...
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Journal articleJ Psychoactive Drugs · December 2007
Using ambulatory methods for monitoring, this study investigated gender differences regarding the association between smoking and situational cues in 63 smokers with posttraumatic stress disorder (PTSD) and 32 smokers without PTSD. Smokers were instructed ...
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Journal articleJ Trauma Stress · December 2007
Although sleep disturbance is considered a hallmark of posttraumatic stress disorder (PTSD), objective evidence for sleep disturbance in patients with PTSD has been equivocal. The goal of the current investigation was to objectively examine sleep disturban ...
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Journal articleJ Trauma Stress · December 2007
Posttraumatic stress disorder (PTSD) is associated with a high prevalence of cigarette smoking, heavy cigarette consumption, and low cessation rates. To date, little is known about mechanisms impeding smoking cessation among this recalcitrant group of smok ...
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Journal article · December 1, 2007
There is a high incidence of exposure to traumatic experiences in the U.S. general population. The majority of the population at some time in their lives experience a distressing and traumatic event. Two common psychiatric conditions that occur post-trauma ...
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Journal articleNicotine Tob Res · November 2007
We conducted a systematic review of what is known about the relationship between post-traumatic stress disorder (PTSD) and smoking to guide research on underlying mechanisms and to facilitate the development of evidence-based tobacco treatments for this po ...
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Journal articleJ Trauma Stress · October 2007
The relationship between posttraumatic stress disorder (PTSD) and parasympathetic nervous system functioning was investigated during a baseline rest period and anger recall speaking task using noninvasive estimates of baroreceptor sensitivity. Participants ...
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Journal articleExp Clin Psychopharmacol · June 2007
The present study examined whether reactivity to emotional stressors is related to early relapse from smoking cessation in persons with posttraumatic stress disorder (PTSD). Smokers with PTSD who had failed to sustain any previous quit attempt for 7 days ( ...
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Journal articleGenet Med · June 2007
Genetic factors play a fundamental role in the genesis of many mental disorders. The identification of the underlying genetic variation will therefore transform parts of psychiatry toward a neuroscience-based discipline. With the sequence of the human geno ...
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Journal articleJ Clin Psychopharmacol · April 2007
OBJECTIVE: Although selective serotonin reuptake inhibitors have been the most empirically studied pharmacotherapy for posttraumatic stress disorder (PTSD), a need remains for the investigation of additional pharmacological agents in the treatment of PTSD. ...
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Journal articleJ Pers Assess · February 2007
In this study, we examined the validity of the Personality Assessment Inventory (PAI; Morey, 1991) Aggression (AGG) scales and Violence Potential index (VPI) in 399 male combat veterans presenting for formal evaluation of posttraumatic stress disorder (PTS ...
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Journal articleClin Trials · 2007
BACKGROUND: Post-traumatic stress disorder (PTSD) is associated with a high prevalence of smoking, heavy cigarette consumption and low cessation rates. PURPOSE: This manuscript describes the design of a randomized, multisite effectiveness trial to test whe ...
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Book section · December 22, 2006
There is a high incidence of exposure to traumatic experiences in the U.S. general population. The majority of the population at some time in their lives experience a distressing and traumatic event. Two common psychiatric conditions that occur post-trauma ...
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Journal articleJ Clin Psychiatry · September 2006
OBJECTIVE: This study examined whether trauma exposure before, during, and/or after military service contributed to current levels of post-traumatic stress disorder (PTSD) and adjustment. Further, we investigated whether trauma exposure before military ser ...
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Journal articleJournal of Trauma Practice · March 9, 2006
This paper examines the available information on smoking cessation and posttraumatic stress disorder (PTSD). Unfortunately, there are only two available preliminary smoking cessation intervention studies for smokers with PTSD. The paper first reviews the e ...
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Journal articleBiol Psychol · March 2006
BACKGROUND: The relationship between posttraumatic stress disorder (PTSD) and parasympathetic nervous system (PNS) functioning was investigated using baroreflex sensitivity (BRS). We hypothesized that individuals with PTSD would exhibit lower BRS than thos ...
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Journal articleJournal of Psychopathology and Behavioral Assessment · September 1, 2005
The Personality Assessment Inventory (PAI; L. C. Morey, 1991) is a promising tool for the assessment of Posttraumatic Stress Disorder (PTSD), but few studies have examined the PAI profiles of individuals with the diagnosis. In this study, the PAI was admin ...
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Journal articleExp Clin Psychopharmacol · August 2005
Using ambulatory methods for 1 day of monitoring, the authors of this study investigated the association between smoking and situational cues in 63 smokers with posttraumatic stress disorder (PTSD) and 32 smokers without PTSD. Generalized estimating equati ...
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Journal articleAddict Behav · June 2005
Rates of smoking among individuals with psychiatric conditions are greater than rates seen in the general population, yet little is known about the psychometric properties of commonly used nicotine dependence instruments among psychiatric smokers. This stu ...
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Journal articleAddict Behav · February 2005
Smoking topography was measured in trauma survivors with and without posttraumatic stress disorder (PTSD) after recalling trauma-related and neutral experiences. Analysis of covariance was performed on puff topography and mood measures using nicotine depen ...
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Journal articleJournal of Trauma Practice · January 1, 2005
Two hundred and forty-one Vietnam combat veterans with chronic posttraumatic stress disorder (PTSD) completed measures of PTSD symptom severity, combat exposure, depression, hostility, interpersonal violence, substance abuse, and arrest history. The majori ...
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Journal articleAddict Behav · November 2004
This study investigated the association among cigarette smoking, posttraumatic stress disorder (PTSD), and ambulatory cardiovascular and mood monitoring in 117 male Vietnam combat veterans (61 with PTSD and 56 without PTSD). Positive smoking status was ass ...
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Journal articleJ Trauma Stress · June 2004
This study assessed mental and physical health correlates of dispositional forgiveness and religious coping responses in 213 help-seeking veterans diagnosed with PTSD. Controlling for age, socioeconomic status, ethnicity, combat exposure, and hostility, th ...
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Journal article · January 1, 2004
Fifty veterans diagnosed with posttraumatic stress disorder (PTSD) each recalled four autobiographical memories: one from the 2 years before service, one non-combat memory from the time in service, one from combat, and one from service that had often come ...
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Journal articleJ Trauma Stress · August 2003
This study investigated the associations among PTSD, ambulatory cardiovascular monitoring, and physical health self-reports in 117 male Vietnam combat veterans (61 with PTSD and 56 without PTSD). PTSD was associated with health symptoms and number of curre ...
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Journal articleAm J Psychiatry · December 2002
OBJECTIVE: Posttraumatic stress disorder (PTSD) has been associated with higher rates of health complaints and medical conditions diagnosed by physicians, yet research examining the relationship between PTSD and health care utilization has been limited. Th ...
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Journal articleAnn Clin Psychiatry · December 2002
Multiyear (37-51 months) follow-up data was obtained on patients who had participated in an open label trial of nefazodone that originally showed nefazodone may be useful for symptom management in posttraumatic stress disorder (PTSD) patients. Ten patients ...
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Journal articleJ Clin Psychol · December 2002
This study investigated whether a subgroup of veterans with malignant posttraumatic stress syndrome, as described by Rosenheck (1985) and Lambert et al. (1996), could be identified via cluster analysis within two samples of Vietnam veterans with combat-rel ...
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Journal articleJ Pers Assess · December 2002
Researchers have identified difficulties associated with the use of traditional Minnesota Multiphasic Personality Inventory-2 (MMPI-2; Butcher, Dahlstrom, Graham, Tellegen, & Kaemmer, 1989) validity scales with survivors of traumatic events. A new scale, t ...
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Journal articleViolence Vict · August 2002
The current study provides a portrait of emotional-behavioral functioning within a small sample of Vietnam veterans with combat-related posttraumatic stress disorder (PTSD), their partners, and older adolescent and adult children. Veterans, their partners ...
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Journal articleJ Trauma Stress · June 2002
Caregiver burden and psychological distress were examined in a sample of 71 partners of Vietnam War combat veterans. Partners of patients (n = 51) diagnosed with posttraumatic stress disorder (PTSD) experienced more caregiver burden and had poorer psycholo ...
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Journal articleJ Trauma Stress · April 2002
Spouse reports may serve as an important source of collateral information in the assessment of posttraumatic stress disorder (PTSD) and associated behavioral problems. This study examined the concordance of anger reports among 94 combat veterans and their ...
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Journal articleJ Clin Psychol · April 2002
Personality disorders were examined in 157 incarcerated women, using the Schedule for Nonadaptive and Adaptive Personality (SNAP; Clark, 1996) to assess 10 Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised (DSM-III-R; American P ...
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Journal articleJ Clin Psychol · April 2002
The current study examined service era differences in a sample of 172 Gulf and Vietnam outpatient veterans with combat-related posttraumatic stress disorder (PTSD). Participants completed the MMPI-2 and several additional self-report measures of symptom se ...
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Journal articleJ Consult Clin Psychol · February 2002
This study investigated the cardiovascular responses to a relived anger task in 118 male Vietnam combat veterans (62 with posttraumatic stress disorder [PTSD] and 56 without PTSD). Participants completed standardized diagnostic measures, hostility measures ...
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Journal articleAnn Behav Med · 2002
A large body of evidence indicates that hostility is related to increased morbidity and mortality and evidence is growing that posttraumatic stress disorder (PTSD) is associated with poorer health outcomes. The majority of this research, however, has been ...
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Journal articleJ Clin Psychopharmacol · February 2001
This study was conducted to evaluate the effect of bupropion sustained-release (SR) on smoking cessation in patients with chronic posttraumatic stress disorder (PTSD). Fifteen veterans with chronic PTSD who desired to stop smoking enrolled in a 12-week dou ...
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Journal articleJ Pers Assess · October 2000
This study examined whether individuals who were instructed on the Diagnostic and Statistical Manual of Mental Disorders (4th ed. [DSM-IV]; American Psychiatric Association, 1994) criteria for posttraumatic stress disorder (PTSD) could feign PTSD on the Pe ...
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Journal articleJ Consult Clin Psychol · October 2000
The present study assessed drug use and the validity of self-reports of substance use among help-seeking veterans referred to a specialty clinic for the assessment of posttraumatic stress disorder (PTSD). Patients (n = 341) were asked to provide a urine sa ...
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Journal articleJ Trauma Stress · October 2000
This study investigated hostility and functional health status in 90 women veterans with and without PTSD. Compared to women without PTSD, women veterans with PTSD reported significantly higher levels of hostility. Minority status was associated with incre ...
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Journal articleAnn Clin Psychiatry · June 2000
BACKGROUND: Fluoxetine and placebo were studied in a population of combat veterans with severe, chronic PTSD. METHODS: Twelve male veterans with PTSD were enrolled in a 12 week double-blind evaluation of fluoxetine and placebo. Mean fluoxetine dose at endp ...
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Journal articleJ Consult Clin Psychol · April 2000
The present study investigated the relationship between daily diary affect ratings and ambulatory cardiovascular activity in 117 male Vietnam combat veterans (61 with posttraumatic stress disorder [PTSD] and 56 without PTSD). Participants completed 12-14 h ...
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Journal articleAggression and Violent Behavior · January 1, 2000
There is strong evidence that anger and violence are prevalent problems in Vietnam combat veterans with posttraumatic stress disorder, and a summary of relevant empirical studies is presented. However, the pathways responsible for development and perpetuat ...
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Journal articleBiol Psychiatry · May 1, 1999
BACKGROUND: The anticonvulsant, lamotrigine, may be useful for symptom management in PTSD. METHODS: Subjects enrolled in a 12-week double-blind evaluation of lamotrigine and placebo. Patients were randomized 2:1 to either lamotrigine or placebo. Lamotrigin ...
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Journal articleJ Psychoactive Drugs · 1999
There is growing evidence that smoking, and in particular heavy smoking, is prevalent in Vietnam combat veterans with posttraumatic stress disorder. However, the pathways responsible for development and perpetuation of smoking in this clinical population h ...
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Journal articleJ Behav Med · December 1998
Scores on the Rotter Interpersonal Trust Scale were evaluated as predictors of psychological well-being, functional health, and longevity in a sample of 100 men and women who were between 55 and 80 years old at baseline (mean age 66.8). Cross-sectionally, ...
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Journal articleAm J Psychiatry · November 1998
OBJECTIVE: A two-part study was conducted to examine the health status of Vietnam veterans with posttraumatic stress disorder (PTSD). In part 1, veterans with and without PTSD were compared on health behaviors and on self-reported and physician-rated healt ...
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Journal articleJ Trauma Stress · October 1998
The present study investigated variables associated with performance on the Trail Making Test from the Halstead-Reitan neuropsychological test battery in Vietnam combat veterans. There was a significant difference in performance between veterans with and w ...
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Journal articleJ Clin Psychiatry · September 1998
BACKGROUND: Because of its ability to block 5-HT2 receptors postsynaptically and inhibit 5-HT reuptake presynaptically and/or its enhancement of sleep quality, nefazodone may be useful for symptom management in posttraumatic stress disorder (PTSD) patients ...
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Journal articleJ Clin Psychol · December 1997
Two studies were conducted to investigate interpersonal violence in Vietnam veterans with posttraumatic stress disorder (PTSD). In study one, combat veterans with PTSD reported significantly greater occurrence of violent behaviors over the past year (22 ac ...
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Journal articleJ Clin Psychol · December 1997
Forty children of 28 fathers who are Vietnam veterans with posttraumatic stress disorder (PTSD) completed the Minnesota Multiphasic Personality Inventory. Each of the fathers had at least one elevated clinical scale. Fathers averaged eight elevated clinica ...
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Journal articleJ Psychosom Res · October 1997
A study was conducted to investigate chronic pain patterns in Vietnam veterans with posttraumatic stress disorder (PTSD). Combat veterans with PTSD completed standardized PTSD severity, pain, somatization, and depression measures. Of 129 consecutive out-pa ...
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Journal articleAddict Behav · 1997
A study was conducted to investigate smoking patterns in 445 Vietnam veterans with and without posttraumatic stress disorder (PTSD). Combat veterans with PTSD reported similar occurrence of smoking (53%) compared to combat veterans without PTSD (45%). For ...
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Journal articlePsychol Med · January 1997
BACKGROUND: In post-traumatic stress disorder (PTSD) there is a need for self-rating scales that are sensitive to treatment effects and have been tested in a broad range of trauma survivors. Separate measures of frequency and severity may also provide an a ...
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Journal articleBehav Med · 1997
The relation between cancer self-efficacy and patient cancer adjustment, depression, psychological distress, and behavioral dysfunction in 42 cancer patients was studied in a preliminary investigation. Participants were male cancer outpatients recruited fr ...
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Journal articleJ Consult Clin Psychol · October 1996
Caregiver burden in 58 partners of Vietnam veterans with posttraumatic stress disorder (PTSD) was examined. The relationship between patient PTSD severity and caregiver burden, as well as the effect of several caregiver and patient variables on caregiver p ...
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Journal articleJ Clin Psychopharmacol · August 1996
Six patients with combat-related posttraumatic stress disorder (PTSD) entered a multiple-baseline trial of trazodone, beginning with 50 mg/day and increasing to 400 mg/day until response was maximal. Total Clinician-Administered PTSD Scale scores decreased ...
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Journal articleJ Trauma Stress · April 1996
The present study investigated self-reported and interpersonal hostility in 70 Vietnam combat veterans with and without posttraumatic stress disorder (PTSD) and 60 comparison community volunteer subjects. Veterans were 50 help-seeking, male Vietnam combat ...
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Journal articleAddict Behav · 1996
This study investigated the relationship between a trauma-related stressor and smoking withdrawal symptoms in 25 male Vietnam combat veterans with posttraumatic stress disorder (PTSD) using a within-subjects design. All subjects were smokers. The stressor ...
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Journal articleJ Trauma Stress · July 1995
The present study investigated smoking prevalence, smoking motives, demographic variables and psychological symptoms in 124 help-seeking, male Vietnam combat veterans with post-traumatic stress disorder (PTSD). A high percentage of these veterans smoked (6 ...
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Journal articleJournal of Anxiety Disorders · January 1, 1995
This study investigated Stroop color-naming of trauma-related words in male Vietnam combat veterans with (n = 42) and without (n = 15) posttraumatic stress disorder (PTSD). The anxiety connotations of the words were either very specific to the Vietnam expe ...
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Journal articleBehav Med · 1995
The authors of the present study investigated the relationship between rheumatoid arthritis (RA) patients' demographic, medical, and functional status and caregivers' burden, optimism, and pessimism. Subjects were 65 RA patients and their caregivers who we ...
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Journal articleCognitive Therapy and Research · October 1, 1994
The present study investigated the interrelationship of several commonly used arthritis-related cognitive measures and their relationship to physical disability, pain, depression, and anxiety in rheumatoid arthritis (RA)_patients. Subjects were 103 RA pati ...
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Journal articleJ Psychosom Res · July 1994
This study was designed to evaluate the efficacy of a brief, structured pain management program to improve control over chest pain episodes in patients diagnosed with coronary artery disease. Twenty-six male veterans who attended the three-session program ...
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Journal articleJournal of Cardiopulmonary Rehabilitation · January 1, 1994
Purpose. This study was conducted to investigate the relationship of pain coping strategies to functional status, pain, psychological distress, and depression in 72 chronic angina patients referred for diagnostic coronary angiography. Methods. Each subject ...
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Journal articlePsychol Aging · March 1993
Multiple measures of hostility were administered to middle-aged and older volunteers. There was a positive association between age and self-report measures reflecting hostile beliefs about others, including cynicism and suspiciousness. There was a weak inv ...
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Journal articleCan J Psychiatry · October 1992
This study examined the degree to which depression is related to physical and psychosocial dysfunction. The Beck Depression Inventory and the Sickness Impact Profile were administered to 34 patients with rheumatoid arthritis. Information on the demographic ...
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Journal articleJ Clin Immunol · September 1992
Rheumatoid arthritis is a complex inflammatory disease of unknown cause. Although various laboratory and clinical measurements are useful in managing these patients, there is a need for better tests to quantitatively assess disease activity. The purpose of ...
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Journal articleHeadache · June 1992
Fourteen female volunteers who met diagnostic criteria for migraine headache monitored their headache activity and menstrual distress symptoms for one menstrual cycle. Serum estradiol and progesterone levels, and menstrual distress measures were collected ...
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Journal articleJ Consult Clin Psychol · February 1992
A high percentage of patients who undergo diagnostic angiography because they have chest pain are found to be free of significant coronary artery disease. To examine the psychological characteristics of these patients, we used several Minnesota Multiphasic ...
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Journal articlePain · August 1991
This study used the Coping Strategies Questionnaire (CSQ) to investigate pain coping strategies in 52 rheumatoid arthritis patients who reported having knee pain 1 year or more following knee replacement surgery. Data analysis revealed that, as a group, th ...
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Journal articleJournal of Counseling Psychology · April 1, 1991
The efficacy of stress-inoculation bibliotherapy for 121 test-anxious college students was examined. A phone-contact condition and a no-contact, stress-inoculation bibliotherapy condition were compared with a phone-contact, wait-list control condition and ...
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Journal articleBiofeedback Self Regul · March 1991
This paper presents a single case controlled study of a 75-year-old male having bilateral total knee replacement. Baseline EMG recordings demonstrated differential levels of vastus medialis and vastus lateralis muscle activity in both knees during exercise ...
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Journal articleBehavior Therapy · January 1, 1991
The present study investigated the relation of pain coping strategies to physical disability, pain, psychological disability, depression and daily hassles in rheumatoid arthritis (RA) patients. Subjects were 65 RA patients recruited from an outpatient rheu ...
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Journal articleJ Behav Ther Exp Psychiatry · September 1990
Minimal-therapist-involvement stress inoculation training was used to treat flying phobics. Relative to no-treatment controls, treatment subjects reported more fear reduction, were more likely to participate in an exposure session, and flew more during a t ...
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Journal articleJournal of Psychosocial Oncology · June 4, 1990
Although a number of articles about the sexual functioning of cancer patients have been published, relatively few have described empirical investigations or integrated approaches to the subject. This article reviews recent studies of patients who have brea ...
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Journal articleBehavior Therapy · January 1, 1990
The purpose of this study was to determine whether a cognitive-behavioral intervention designed to improve pain coping skills could reduce pain, physical disability, psychological disability, and pain behavior in osteoarthritic knee pain patients. Patients ...
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Journal articleAnesth Prog · 1990
Orofacial pain is usually evaluated and treated from a biomedical perspective. There is no question that the large majority of individuals having acute orofacial pain benefit from timely and appropriate medical intervention. When orofacial pain persists, h ...
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Journal articleBehavior Therapy · January 1, 1990
This study examines the degree to which negative thoughts during flare-ups of pain are related to pain and psychological distress in three pain populations, sickle cell disease, rheumatoid arthritis, and chronic pain. One-hundred eighty-five subjects compl ...
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Journal articleBehavior Therapy · January 1, 1990
This study examines six months follow-up data obtained from osteoarthritic knee pain patients participating in a study comparing pain coping skills training, arthritis education, and a standard care control condition. At the time of follow-up, patients rec ...
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Journal articleLaw and Human Behavior · March 1, 1989
Source of nomination (prosecution, defense, judge) was varied in a fictional not guilty by reason of insanity (NGRI) case distributed to 180 community forensic evaluators in a state employing the M'Naghten rule. Differences among examiners by appointment f ...
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Journal articleJournal of Psychology Interdisciplinary and Applied · January 1, 1988
In this study we investigated sex differences, the effects of problem context, and subject sex-role type on subject's problem-solving ability. The 160 subjects (80 men and 80 women) were students from introductory psychology classes. They were chosen so th ...
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Journal articleCriminal Justice and Behavior · January 1, 1986
Data for two samples of competent defendants were collected from hospital records in order to determine group differences for those who maintain competency to stand trial (nonrecidivists) versus those who do not maintain competency (recidivists). Stepwise ...
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Journal articleDevelopmental Psychology · November 1, 1982
60 kindergartners, 4th graders, and 8th graders and 32 college students took part in a game of chance and a game of skill. After each game, Ss predicted the winnings of other players who differed in certain attributes (e.g., IQ) and behavior (e.g., effort) ...
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