Current Appointments & Affiliations
James R. Urbaniak, M.D., Distinguished Professor of Orthopedic Surgery
·
2013 - Present
Orthopaedic Surgery,
Clinical Science Departments
Professor of Orthopaedic Surgery
·
2013 - Present
Orthopaedic Surgery,
Clinical Science Departments
Chair of Orthopaedic Surgery
·
2013 - Present
Orthopaedic Surgery,
Clinical Science Departments
Professor in Pediatrics
·
2014 - Present
Pediatrics,
Clinical Science Departments
Professor in Cell Biology
·
2014 - Present
Cell Biology,
Basic Science Departments
Professor in the Department of Pathology
·
2015 - Present
Pathology,
Clinical Science Departments
Professor in Pharmacology and Cancer Biology
·
2020 - Present
Pharmacology & Cancer Biology,
Basic Science Departments
Professor in Neurosurgery
·
2022 - Present
Neurosurgery,
Neurosurgery
Member of the Duke Cancer Institute
·
2013 - Present
Duke Cancer Institute,
Institutes and Centers
Co-Director of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Publications
Impact of Lumbar Degenerative Changes on Vertebral Bone Strength: A Finite Element Analysis.
Journal Article J Orthop Res · February 4, 2025 Assessing the bone condition in patients with spinal disease is clinically valuable. However, evaluating bone strength in the presence of spine degenerative changes is challenging. Quantitative computed tomography (QCT) and finite element analysis (FEA) ha ... Full text Link to item CiteSingle cell analysis of Idh mutant growth plates identifies cell populations responsible for longitudinal bone growth and enchondroma formation.
Journal Article Sci Rep · October 31, 2024 Enchondromas are a common tumor in bone that can occur as multiple lesions in enchondromatosis, which is associated with deformity of the affected bone. These lesions harbor somatic mutations in IDH and driving expression of a mutant Idh1 in Col2 expressin ... Full text Link to item CiteThe COMPASS complex maintains the metastatic capacity imparted by a subpopulation of cells in UPS.
Journal Article iScience · July 19, 2024 Intratumoral heterogeneity is common in cancer, particularly in sarcomas like undifferentiated pleomorphic sarcoma (UPS), where individual cells demonstrate a high degree of cytogenic diversity. Previous studies showed that a small subset of cells within U ... Full text Link to item CiteRecent Grants
Boston Children's/UCLA/Duke Next Generation Regeneration for Osteoarthritis (BUD NextGenRegen for OA)
ResearchPrincipal Investigator · Awarded by Advanced Research Projects Agency for Health · 2024 - 2029The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program
ResearchPreceptor · Awarded by National Cancer Institute · 2023 - 2028Advancing Cancer Therapy through Groundbreaking Research in Radiation Biology
ResearchPrincipal Investigator · Awarded by Roswell Park Cancer Institute · 2023 - 2028View All Grants
Education, Training & Certifications
Thomas Jefferson University, Sidney Kimmel Medical College ·
1986
M.D.