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Benjamin B Albright

Adjunct Assistant Professor in the Department of Obstetrics and Gynecology
Obstetrics and Gynecology, Gynecologic Oncology

Selected Publications


Catastrophic health expenditures, insurance churn, and non-employment among women with breast cancer.

Journal Article JNCI Cancer Spectr · February 29, 2024 BACKGROUND: Breast cancer treatment and survivorship entails a complex and expensive continuum of subspecialty care. Our objectives were to assess catastrophic health expenditures, insurance churn, and non-employment among women younger than 65 years who r ... Full text Link to item Cite

Efficacy of cyclin-dependent kinase 4/6 inhibitors in combination with hormonal therapy in patients with recurrent granulosa cell tumor of the ovary: A case series.

Journal Article Gynecol Oncol Rep · December 2023 Cyclin-dependent kinase inhibitors are approved in combination with hormonal therapy for treatment of hormone receptor expressing breast cancers. Activity in hormone receptor expressing gynecologic cancers has been postulated. Granulosa cell tumor of the o ... Full text Link to item Cite

Geographic variation in the rate and route of hysterectomy for benign disease in the USA: A retrospective cross-sectional study.

Journal Article BJOG · November 2023 OBJECTIVES: To describe population rate of hysterectomy for benign disease in the USA, including geographic variation across states and Hospital Service Areas (HSAs; areas defined by common patient flows to healthcare facilities). DESIGN: Cross-sectional s ... Full text Link to item Cite

Treatments and outcomes in high-risk gestational trophoblastic neoplasia: A systematic review and meta-analysis.

Journal Article BJOG · April 2023 BACKGROUND: High-risk gestational trophoblastic neoplasia (GTN) is rare and treated with diverse approaches. Limited published institutional data has yet to be systematically reviewed. OBJECTIVES: To compile global high-risk GTN (prognostic score ≥7) cohor ... Full text Link to item Cite

Association of Genomic Instability Score, Tumor Mutational Burden, and Tumor-Infiltrating Lymphocytes as Biomarkers in Uterine Serous Carcinoma.

Journal Article Cancers (Basel) · January 15, 2023 Background: Uterine serous carcinomas represent 10% of uterine carcinomas but account for nearly 40% of deaths from the disease. Improved molecular characterization of these tumors is instrumental in guiding targeted treatment and improving outcomes. This ... Full text Link to item Cite

BAP1 Tumor Predisposition Syndrome Presenting as a Recurrent Ovarian Sex Cord-Stromal Tumor.

Journal Article Int J Gynecol Pathol · January 1, 2023 The BRCA1-associated protein 1 ( BAP1 ) gene encodes a tumor suppressor that functions as a ubiquitin hydrolase involved in DNA damage repair. BAP1 germline mutations are associated with increased risk of multiple solid malignancies, including mesothelioma ... Full text Link to item Cite

Telemedicine and gynecologic oncology: caring for patients remotely during a global pandemic

Conference AJOG Global Reports · November 1, 2022 BACKGROUND: Telemedicine uses technology to deliver medical care remotely and has been shown to provide similar patient satisfaction and care outcomes compared with in-person visits. OBJECTIVE: This study aimed to assess the gynecologic oncology patient te ... Full text Cite

Telemedicine and gynecologic oncology: caring for patients remotely during a global pandemic.

Journal Article AJOG Glob Rep · November 2022 BACKGROUND: Telemedicine uses technology to deliver medical care remotely and has been shown to provide similar patient satisfaction and care outcomes compared with in-person visits. OBJECTIVE: This study aimed to assess the gynecologic oncology patient te ... Full text Link to item Cite

Out-of-network bills among privately insured patients undergoing hysterectomy.

Journal Article Am J Obstet Gynecol · April 2022 BACKGROUND: In recent years, the issue of out-of-network billing for privately insured patients has been highlighted as a source of unexpected out-of-pocket charges for patients, even in the setting of an in-network primary surgeon. The Congress recently p ... Full text Link to item Cite

Catastrophic Health Expenditures With Pregnancy and Delivery in the United States.

Journal Article Obstet Gynecol · April 1, 2022 OBJECTIVE: To describe prevalence, trends, and risk factors for catastrophic health expenditures in the year of delivery among birth parents (delivering people). METHODS: We conducted a retrospective, cross-sectional study of the Medical Expenditure Panel ... Full text Link to item Cite

Catastrophic health expenditures, insurance churn, and nonemployment among gynecologic cancer patients in the United States.

Journal Article Am J Obstet Gynecol · March 2022 BACKGROUND: In recent years, there has been growing recognition of the financial burden of severe illness, including associations with higher rates of nonemployment, uninsurance, and catastrophic out-of-pocket health spending. Patients with gynecologic can ... Full text Link to item Cite

Employment outcomes among cancer patients in the United States.

Journal Article Cancer Epidemiol · February 2022 BACKGROUND: Cancer diagnosis and treatment can lead to disruptions in employment, which can, in turn, lead to financial problems and uninsurance. We used a nationally representative survey to describe predictors of non-employment among cancer patients comp ... Full text Link to item Cite

Adjuvant treatment and outcomes for patients with stage IIIA grade 1 endometrioid endometrial cancer.

Journal Article Int J Gynecol Cancer · December 2021 OBJECTIVE: The role and type of adjuvant therapy for patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIIA grade 1 endometrioid endometrial adenocarcinoma are controversial. This retrospective cohort study aimed to determine ... Full text Link to item Cite

Surveillance for gestational trophoblastic neoplasia following molar pregnancy: a cost-effectiveness analysis.

Journal Article Am J Obstet Gynecol · November 2021 BACKGROUND: Historically, published guidelines for care after molar pregnancy recommended monitoring human chorionic gonadotropin levels for the development of gestational trophoblastic neoplasia until normal and then for 6 months after the first normal hu ... Full text Link to item Cite

Neoadjuvant chemotherapy for advanced stage endometrial cancer: A systematic review.

Journal Article Gynecol Oncol Rep · November 2021 OBJECTIVE: While primary cytoreductive surgery (PCS) is considered the standard of care for women who present with stage IV endometrial cancer, neoadjuvant chemotherapy (NACT) followed by interval cytoreductive surgery (ICS) has emerged as an alternative t ... Full text Link to item Cite

Primary cytoreductive surgery for advanced stage endometrial cancer: a systematic review and meta-analysis.

Journal Article Am J Obstet Gynecol · September 2021 OBJECTIVE: Endometrial cancer uncommonly presents at an advanced stage and little prospective evidence exists to guide the management thereof. We aimed to summarize the evidence about primary cytoreductive surgery in the treatment of advanced stage endomet ... Full text Link to item Cite

Use and outcomes of neoadjuvant chemotherapy for metastatic uterine cancer.

Journal Article Gynecol Oncol · September 2021 OBJECTIVE: Neoadjuvant chemotherapy (NACT) has emerged as an alternative to primary cytoreductive surgery (PCS) for stage IV uterine cancer. We examined utilization, perioperative outcomes and survival for NACT and PCS for stage IV uterine cancer. METHODS: ... Full text Link to item Cite

Associations of Insurance Churn and Catastrophic Health Expenditures With Implementation of the Affordable Care Act Among Nonelderly Patients With Cancer in the United States.

Journal Article JAMA Netw Open · September 1, 2021 IMPORTANCE: Health insurance coverage is dynamic in the United States, potentially changing from month to month. The Patient Protection and Affordable Care Act (ACA) aimed to stabilize markets and reduce financial burden, particularly among those with pree ... Full text Link to item Cite

Medicaid Expansion Reduced Uninsured Surgical Hospitalizations And Associated Catastrophic Financial Burden.

Journal Article Health Aff (Millwood) · August 2021 An important function of health insurance is protecting enrollees from excessively burdensome charges for unanticipated medical events. Unexpected surgery can be financially catastrophic for uninsured people. By targeting the low-income uninsured populatio ... Full text Link to item Cite

Evaluation of the clinical Index of Stable febrile neutropenia risk stratification system for management of febrile neutropenia in gynecologic oncology patients.

Journal Article Gynecol Oncol Rep · August 2021 OBJECTIVE: Scoring systems have been developed to identify low risk patients with febrile neutropenia (FN) who may be candidates for outpatient management. We sought to validate the predictive accuracy of the Clinical Index of Stable Febrile Neutropenia (C ... Full text Link to item Cite

Catastrophic health expenditures, insurance churn, and non-employment among women with breast cancer.

Journal Article JNCI Cancer Spectr · February 29, 2024 BACKGROUND: Breast cancer treatment and survivorship entails a complex and expensive continuum of subspecialty care. Our objectives were to assess catastrophic health expenditures, insurance churn, and non-employment among women younger than 65 years who r ... Full text Link to item Cite

Efficacy of cyclin-dependent kinase 4/6 inhibitors in combination with hormonal therapy in patients with recurrent granulosa cell tumor of the ovary: A case series.

Journal Article Gynecol Oncol Rep · December 2023 Cyclin-dependent kinase inhibitors are approved in combination with hormonal therapy for treatment of hormone receptor expressing breast cancers. Activity in hormone receptor expressing gynecologic cancers has been postulated. Granulosa cell tumor of the o ... Full text Link to item Cite

Geographic variation in the rate and route of hysterectomy for benign disease in the USA: A retrospective cross-sectional study.

Journal Article BJOG · November 2023 OBJECTIVES: To describe population rate of hysterectomy for benign disease in the USA, including geographic variation across states and Hospital Service Areas (HSAs; areas defined by common patient flows to healthcare facilities). DESIGN: Cross-sectional s ... Full text Link to item Cite

Treatments and outcomes in high-risk gestational trophoblastic neoplasia: A systematic review and meta-analysis.

Journal Article BJOG · April 2023 BACKGROUND: High-risk gestational trophoblastic neoplasia (GTN) is rare and treated with diverse approaches. Limited published institutional data has yet to be systematically reviewed. OBJECTIVES: To compile global high-risk GTN (prognostic score ≥7) cohor ... Full text Link to item Cite

Association of Genomic Instability Score, Tumor Mutational Burden, and Tumor-Infiltrating Lymphocytes as Biomarkers in Uterine Serous Carcinoma.

Journal Article Cancers (Basel) · January 15, 2023 Background: Uterine serous carcinomas represent 10% of uterine carcinomas but account for nearly 40% of deaths from the disease. Improved molecular characterization of these tumors is instrumental in guiding targeted treatment and improving outcomes. This ... Full text Link to item Cite

BAP1 Tumor Predisposition Syndrome Presenting as a Recurrent Ovarian Sex Cord-Stromal Tumor.

Journal Article Int J Gynecol Pathol · January 1, 2023 The BRCA1-associated protein 1 ( BAP1 ) gene encodes a tumor suppressor that functions as a ubiquitin hydrolase involved in DNA damage repair. BAP1 germline mutations are associated with increased risk of multiple solid malignancies, including mesothelioma ... Full text Link to item Cite

Telemedicine and gynecologic oncology: caring for patients remotely during a global pandemic

Conference AJOG Global Reports · November 1, 2022 BACKGROUND: Telemedicine uses technology to deliver medical care remotely and has been shown to provide similar patient satisfaction and care outcomes compared with in-person visits. OBJECTIVE: This study aimed to assess the gynecologic oncology patient te ... Full text Cite

Telemedicine and gynecologic oncology: caring for patients remotely during a global pandemic.

Journal Article AJOG Glob Rep · November 2022 BACKGROUND: Telemedicine uses technology to deliver medical care remotely and has been shown to provide similar patient satisfaction and care outcomes compared with in-person visits. OBJECTIVE: This study aimed to assess the gynecologic oncology patient te ... Full text Link to item Cite

Out-of-network bills among privately insured patients undergoing hysterectomy.

Journal Article Am J Obstet Gynecol · April 2022 BACKGROUND: In recent years, the issue of out-of-network billing for privately insured patients has been highlighted as a source of unexpected out-of-pocket charges for patients, even in the setting of an in-network primary surgeon. The Congress recently p ... Full text Link to item Cite

Catastrophic Health Expenditures With Pregnancy and Delivery in the United States.

Journal Article Obstet Gynecol · April 1, 2022 OBJECTIVE: To describe prevalence, trends, and risk factors for catastrophic health expenditures in the year of delivery among birth parents (delivering people). METHODS: We conducted a retrospective, cross-sectional study of the Medical Expenditure Panel ... Full text Link to item Cite

Catastrophic health expenditures, insurance churn, and nonemployment among gynecologic cancer patients in the United States.

Journal Article Am J Obstet Gynecol · March 2022 BACKGROUND: In recent years, there has been growing recognition of the financial burden of severe illness, including associations with higher rates of nonemployment, uninsurance, and catastrophic out-of-pocket health spending. Patients with gynecologic can ... Full text Link to item Cite

Employment outcomes among cancer patients in the United States.

Journal Article Cancer Epidemiol · February 2022 BACKGROUND: Cancer diagnosis and treatment can lead to disruptions in employment, which can, in turn, lead to financial problems and uninsurance. We used a nationally representative survey to describe predictors of non-employment among cancer patients comp ... Full text Link to item Cite

Adjuvant treatment and outcomes for patients with stage IIIA grade 1 endometrioid endometrial cancer.

Journal Article Int J Gynecol Cancer · December 2021 OBJECTIVE: The role and type of adjuvant therapy for patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIIA grade 1 endometrioid endometrial adenocarcinoma are controversial. This retrospective cohort study aimed to determine ... Full text Link to item Cite

Surveillance for gestational trophoblastic neoplasia following molar pregnancy: a cost-effectiveness analysis.

Journal Article Am J Obstet Gynecol · November 2021 BACKGROUND: Historically, published guidelines for care after molar pregnancy recommended monitoring human chorionic gonadotropin levels for the development of gestational trophoblastic neoplasia until normal and then for 6 months after the first normal hu ... Full text Link to item Cite

Neoadjuvant chemotherapy for advanced stage endometrial cancer: A systematic review.

Journal Article Gynecol Oncol Rep · November 2021 OBJECTIVE: While primary cytoreductive surgery (PCS) is considered the standard of care for women who present with stage IV endometrial cancer, neoadjuvant chemotherapy (NACT) followed by interval cytoreductive surgery (ICS) has emerged as an alternative t ... Full text Link to item Cite

Primary cytoreductive surgery for advanced stage endometrial cancer: a systematic review and meta-analysis.

Journal Article Am J Obstet Gynecol · September 2021 OBJECTIVE: Endometrial cancer uncommonly presents at an advanced stage and little prospective evidence exists to guide the management thereof. We aimed to summarize the evidence about primary cytoreductive surgery in the treatment of advanced stage endomet ... Full text Link to item Cite

Use and outcomes of neoadjuvant chemotherapy for metastatic uterine cancer.

Journal Article Gynecol Oncol · September 2021 OBJECTIVE: Neoadjuvant chemotherapy (NACT) has emerged as an alternative to primary cytoreductive surgery (PCS) for stage IV uterine cancer. We examined utilization, perioperative outcomes and survival for NACT and PCS for stage IV uterine cancer. METHODS: ... Full text Link to item Cite

Associations of Insurance Churn and Catastrophic Health Expenditures With Implementation of the Affordable Care Act Among Nonelderly Patients With Cancer in the United States.

Journal Article JAMA Netw Open · September 1, 2021 IMPORTANCE: Health insurance coverage is dynamic in the United States, potentially changing from month to month. The Patient Protection and Affordable Care Act (ACA) aimed to stabilize markets and reduce financial burden, particularly among those with pree ... Full text Link to item Cite

Medicaid Expansion Reduced Uninsured Surgical Hospitalizations And Associated Catastrophic Financial Burden.

Journal Article Health Aff (Millwood) · August 2021 An important function of health insurance is protecting enrollees from excessively burdensome charges for unanticipated medical events. Unexpected surgery can be financially catastrophic for uninsured people. By targeting the low-income uninsured populatio ... Full text Link to item Cite

Evaluation of the clinical Index of Stable febrile neutropenia risk stratification system for management of febrile neutropenia in gynecologic oncology patients.

Journal Article Gynecol Oncol Rep · August 2021 OBJECTIVE: Scoring systems have been developed to identify low risk patients with febrile neutropenia (FN) who may be candidates for outpatient management. We sought to validate the predictive accuracy of the Clinical Index of Stable Febrile Neutropenia (C ... Full text Link to item Cite

Oncologic outcomes of minimally invasive versus open radical hysterectomy for early stage cervical carcinoma and tumor size <2 cm: a systematic review and meta-analysis.

Journal Article Int J Gynecol Cancer · July 2021 OBJECTIVE: To investigate the oncologic outcomes of patients with early-stage cervical carcinoma and tumor size <2 cm who underwent open or minimally invasive radical hysterectomy. METHODS: The Pubmed/Medline, Embase, and Web-of-Science databases were quer ... Full text Link to item Cite

Emergency department utilization by patients with gynecologic cancer in the United States.

Journal Article Int J Gynecol Cancer · April 2021 INTRODUCTION: Payment reform will give oncologists increasing responsibility for how patients with cancer meet unexpected care needs. OBJECTIVE: To differentiate how patients with gynecologic cancers use emergency care, and to assess the characteristics as ... Full text Link to item Cite

Impact of Medicaid expansion on women with gynecologic cancer: a difference-in-difference analysis.

Journal Article Am J Obstet Gynecol · February 2021 BACKGROUND: Women with gynecologic cancer face socioeconomic disparities in care that affect survival outcomes. The Affordable Care Act offered states the option to expand Medicaid enrollment eligibility criteria as a means of improving timely and affordab ... Full text Link to item Cite

Perioperative outcomes and disparities in utilization of sentinel lymph node biopsy in minimally invasive staging of endometrial cancer.

Journal Article Gynecol Oncol · December 2020 OBJECTIVE: To assess the emergence of sentinel lymph node biopsy (SLNB) for disparities in utilization, and impacts on perioperative outcomes. METHODS: Retrospective cohort study of the National Cancer Database, selecting for patients with T1NxM0 endometri ... Full text Link to item Cite

In Reply.

Journal Article Obstet Gynecol · May 2020 Full text Link to item Cite

Advanced stage primary mucinous ovarian carcinoma. Where do we stand ?

Journal Article Arch Gynecol Obstet · April 2020 OBJECTIVE: To evaluate factors associated with survival of patients with advanced stage mucinous ovarian carcinoma (MOC) using a large multi-institutional database. METHODS: Patients diagnosed between 2004 and 2014 with advanced stage (III-IV) MOC were ide ... Full text Link to item Cite

Gestational Trophoblastic Neoplasia After Human Chorionic Gonadotropin Normalization Following Molar Pregnancy: A Systematic Review and Meta-analysis.

Journal Article Obstet Gynecol · January 2020 OBJECTIVE: To estimate the incidence of gestational trophoblastic neoplasia following complete and partial molar pregnancy after reaching normal human chorionic gonadotropin (hCG) levels to guide evidence-based follow-up recommendations. DATA SOURCES: MEDL ... Full text Link to item Cite

Treat-and-Release Emergency Department Utilization by Patients With Gynecologic Cancers.

Journal Article J Oncol Pract · May 2019 PURPOSE: Seventeen percent of patients with cancer visit the emergency department (ED) annually, often with nonemergent complaints. We sought to describe the burden of treat-and-release ED utilization by patients with gynecologic cancers and to identify op ... Full text Link to item Cite

Ten-Year Comparison Study of Type 1 and 2 Endometrial Cancers: Risk Factors and Outcomes.

Journal Article Gynecol Obstet Invest · 2019 AIMS: To compare baseline risk factors for type 1 vs. 2 endometrial cancers and analyze these risk factors for association with overall survival and time to recurrence. METHODS: Retrospective review of 816 consecutive endometrial cancer cases was conducted ... Full text Link to item Cite

Adjuvant chemotherapy for stage I ovarian clear cell carcinoma: Patterns of use and outcomes.

Journal Article Gynecol Oncol · July 2018 OBJECTIVE: The aim of this study was to investigate the patterns of use and outcomes of adjuvant chemotherapy for patients diagnosed with FIGO stage I ovarian clear cell carcinoma (OCCC). METHODS: A cohort of patients diagnosed between 2004 and 2015 with O ... Full text Link to item Cite

Associated characteristics and impact on recurrence and survival of free-floating tumor fragments in the lumen of fallopian tubes in Type I and Type II endometrial cancer.

Journal Article Gynecol Oncol Rep · February 2018 OBJECTIVE: This study sought to evaluate characteristics of cases of free-floating tumor fragments within the lumen of fallopian tubes ('floaters') on final pathology for Type I and Type II endometrial adenocarcinoma, including relationships with disease r ... Full text Link to item Cite

Cost-effectiveness of prophylactic appendectomy: a Markov model.

Conference Surg Endosc · September 2017 BACKGROUND: Appendectomy is the most common emergency surgery performed in the USA. Removal of a non-inflamed appendix during unrelated abdominal surgery (prophylactic or incidental appendectomy) can prevent the downstream risks and costs of appendicitis. ... Full text Link to item Cite

Progressive neuronal activation accompanies epileptogenesis caused by hippocampal glutamine synthetase inhibition.

Journal Article Exp Neurol · February 2017 Loss of glutamine synthetase (GS) in hippocampal astrocytes has been implicated in the causation of human mesial temporal lobe epilepsy (MTLE). However, the mechanism by which the deficiency in GS leads to epilepsy is incompletely understood. Here we ask h ... Full text Link to item Cite

Correction of coagulopathy associated with non-bacterial thrombotic endocarditis (NBTE) by surgical debulking in a case of ovarian clear cell carcinoma.

Journal Article Gynecol Oncol Rep · August 2016 •Ovarian cancer, particularly clear cell carcinoma, creates a hypercoagulable state.•This state can predispose to non-bacterial thrombotic endocarditis (NBTE).•NBTE can embolize and cause widespread arterial infarction.•NBTE is sometimes associated with a ... Full text Link to item Cite

Preventive Care Quality of Medicare Accountable Care Organizations: Associations of Organizational Characteristics With Performance.

Journal Article Med Care · March 2016 BACKGROUND: Accountable Care Organizations (ACOs) are a delivery and payment model aiming to coordinate care, control costs, and improve quality. Medicare ACOs are responsible for 8 measures of preventive care quality. OBJECTIVES: To create composite measu ... Full text Link to item Cite

Robotic Versus Laparoscopic Hysterectomy for Benign Disease: A Systematic Review and Meta-Analysis of Randomized Trials.

Journal Article J Minim Invasive Gynecol · January 2016 We conducted a systematic review and meta-analysis to assess the safety and effectiveness of robotic vs laparoscopic hysterectomy in women with benign uterine disease, as determined by randomized studies. We searched MEDLINE, EMBASE, the Cochrane Library, ... Full text Link to item Cite