Scholarly Works - Book sections
Book section
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March 2, 2017
Despite a multimodal approach involving surgery, radiotherapy, and chemotherapy, the median survival for malignant brain tumor patients is limited to 15-19. months. To improve glioblastoma patient survival, novel therapies targeting the heterogeneous tumor ...
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Book section
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March 2, 2017
Glioblastoma (GBM) is the most malignant primary brain tumor in adults. Even with the current standard of care therapy (i.e., surgery, radiotherapy, and chemotherapy), GBM has a poor prognosis. Innovative immunotherapeutic approaches, which engage a patien ...
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January 1, 2012
Brain tumor biomarkers have long been used as diagnostic tools; they are now finally being brought to bear as therapeutic elements in the fight against brain cancer. Because of the heterogeneity of glial brain tumors, it is clear that no one marker will ev ...
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January 1, 2007
Over the last decades, progress has been made in diagnostic imaging, surgical techniques, radiotherapy, and chemotherapy for the treatment of tumors of the central nervous system. However, the outcome for patients with high-grade gliomas (HGG) has remained ...
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January 1, 2006
Digital karyotyping is a genome-wide approach that is designed to provide a global genomic content profiling of cells at high resolution. In cancer cells, knowledge of gene-specific genetic content alterations has the power to expedite the process of cance ...
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