Jane Elizabeth Blood-Siegfried

Journal article FEMS immunology and medical microbiology · September 2004 Featured Publication Data increasingly implicate a possible role of immune and inflammatory responses to infection in sudden infant death syndrome (SIDS). We have previously described a dual challenge model that results in pathology, organ damage, vascular collapse and unexpla ... Full text Cite

Animal models of sudden unexplained death.

Journal article FEMS immunology and medical microbiology · September 2004 Featured Publication The etiology of sudden infant death syndrome (SIDS) is unknown but thought to be multifactorial. Several animal models have been developed that induce death without pre-existing symptoms and with pathology similar to that seen in SIDS infants; however, the ... Full text Cite

Synergistic effect of influenza a virus on endotoxin-induced mortality in rat pups: a potential model for sudden infant death syndrome.

Journal article Pediatric research · October 2002 Featured Publication Sudden infant death syndrome is the most common cause of postneonatal infant mortality in the developed world. It is a diagnosis of exclusion with peak age of incidence between 2 and 6 mo. Fifty to 63% of these infants have a preexisting upper respiratory ... Full text Cite

Sudden infant death syndrome: a toxic response.

Journal article AACN clinical issues · May 2000 Featured Publication Causes of sudden infant death syndrome (SIDS) remain elusive. Much of the current literature points to an infectious cause with a role for proinflammatory cytokines and septic shock in stimulating an overwhelming response in an infant. This article reviews ... Full text Cite

A historical perspective on the discovery of adenyl purines.

Journal article Biological research for nursing · April 2000 Featured Publication In 1929, Drury and Szent-Gyorgyi described the effects of a simple extract of heart muscle and other tissues on the mammalian heart. This extract was identified as adenylic acid and found to have profound effects on the cardiovascular system. The discovery ... Full text Cite

Monokine production following in vitro stimulation of the THP-1 human monocytic cell line with pertussis vaccine components.

Journal article Journal of clinical immunology · January 1998 Featured Publication Whole-cell pertussis found in diphtheria-tetanus-pertussis (DTP) vaccine can produce symptoms reminiscent of biological responses to circulating proinflammatory monokines such as IL-6, IL-1beta, and TNFalpha. Therefore the ability of pertussis-containing v ... Full text Cite

The challenges of early discharge. Common newborn problems in the first few weeks of life.

Journal article Advance for nurse practitioners · January 1998 Featured Publication In a thorough discussion of a published series on early discharge, Britton, Britton and Beebe note that methodological limitations, study design problems and heterogeneity sorely limit the conclusions that may be drawn from published studies about early di ... Cite