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James Alan Blumenthal

J. P. Gibbons Distinguished Professor Emeritus of Psychiatry
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
Box 3119 Med Ctr, Durham, NC 27710
4567 Hosp South, Durham, NC 27710

Featured Works


Depression and five year survival following acute myocardial infarction: a prospective study.

Journal article J Affect Disord · July 2008 Featured Publication Depression has been shown to be a risk factor for mortality during the 12 months following an acute myocardial infarction (MI), but few studies have examined whether it is associated with increased risk over longer periods. Most of the existing studies uti ... Full text Link to item Cite

Arthritis self-efficacy and self-efficacy for resisting eating: relationships to pain, disability, and eating behavior in overweight and obese individuals with osteoarthritic knee pain.

Journal article Pain · June 2008 Featured Publication This study examined arthritis self-efficacy and self-efficacy for resisting eating as predictors of pain, disability, and eating behaviors in overweight or obese patients with osteoarthritis (OA) of the knee. Patients (N=174) with a body mass index between ... Full text Link to item Cite

Laboratory-based blood pressure recovery is a predictor of ambulatory blood pressure.

Journal article Biol Psychol · March 2008 Featured Publication The recovery phase of the stress response is an individual difference characteristic that may predict cardiovascular risk. The purpose of this study was to examine whether laboratory-based blood pressure (BP) recovery predicts ambulatory BP (ABP). One hund ... Full text Link to item Cite

Effects of exercise and weight loss on depressive symptoms among men and women with hypertension.

Journal article J Psychosom Res · November 2007 Featured Publication OBJECTIVE: This study aimed to investigate changes in depressive symptoms in hypertensive individuals participating in an exercise and weight loss intervention. METHODS: This study involved 133 sedentary men and women with high blood pressure (BP; 130-180 ... Full text Link to item Cite

Effects of extreme hemodilution during cardiac surgery on cognitive function in the elderly.

Journal article Anesthesiology · October 2007 Featured Publication BACKGROUND: Strategies for neuroprotection including hypothermia and hemodilution have been routinely practiced since the inception of cardiopulmonary bypass. Yet postoperative neurocognitive deficits that diminish the quality of life of cardiac surgery pa ... Full text Link to item Cite

Age moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women.

Journal article Arterioscler Thromb Vasc Biol · August 2007 Featured Publication OBJECTIVE: We evaluated age and coronary heart disease (CHD) as potential moderators of the effects of 17beta-estradiol on vascular endothelial function in postmenopausal women. METHODS AND RESULTS: In a double-blind crossover design, 100 postmenopausal wo ... Full text Link to item Cite

Social support and prognosis in patients at increased psychosocial risk recovering from myocardial infarction.

Journal article Health Psychol · July 2007 Featured Publication OBJECTIVE: To compare the impact of network support and different types of perceived functional support on all-cause mortality or nonfatal reinfarction for patients with a recent acute myocardial infarction (AMI). DESIGN: Participants were recruited from t ... Full text Link to item Cite

Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery.

Journal article J Am Coll Cardiol · May 15, 2007 Featured Publication OBJECTIVES: We hypothesized that candidate gene polymorphisms in biologic pathways regulating inflammation, cell matrix adhesion/interaction, coagulation-thrombosis, lipid metabolism, and vascular reactivity are associated with postoperative cognitive defi ... Full text Link to item Cite

Relationship of depression to death or hospitalization in patients with heart failure.

Journal article Arch Intern Med · February 26, 2007 Featured Publication BACKGROUND: Depression is widely recognized as a risk factor in patients with coronary heart disease. However, patients with heart failure (HF) have been less frequently studied, and the effect of depression on prognosis, independent of disease severity, i ... Full text Link to item Cite

Heart failure and a controlled trial investigating outcomes of exercise training (HF-ACTION): design and rationale.

Journal article Am Heart J · February 2007 Featured Publication BACKGROUND: Although there are limited clinical data to support the use of exercise training as a means to reduce mortality and morbidity in patients with heart failure, current guidelines state that exercise is beneficial. TRIAL DESIGN: The objective of t ... Full text Link to item Cite

Psychosocial training and cardiac rehabilitation.

Journal article J Cardiopulm Rehabil Prev · 2007 Featured Publication Full text Link to item Cite

Heart rate turbulence, depression, and survival after acute myocardial infarction.

Journal article Psychosom Med · January 2007 Featured Publication OBJECTIVE: Depression is a risk factor for mortality after acute myocardial infarction (AMI), possibly as a result of altered autonomic nervous system (ANS) modulation of heart rate (HR) and rhythm. The purposes of this study were to determine: a) whether ... Full text Link to item Cite

Donepezil for cognitive decline following coronary artery bypass surgery: a pilot randomized controlled trial.

Journal article Psychopharmacol Bull · 2007 Featured Publication OBJECTIVE: To study the effect of donepezil in treating patients with cognitive decline following coronary artery bypass graft (CABG) surgery. METHODS: Forty-four patients, with at least a 0.5 SD decline at 1 year post-CABG on at least one cognitive domain ... Link to item Cite

Spirituality, religion, and clinical outcomes in patients recovering from an acute myocardial infarction.

Journal article Psychosom Med · 2007 Featured Publication OBJECTIVE: To assess the prospective relationship between spiritual experiences and health in a sample of patients surviving an acute myocardial infarction (AMI) with depression or low social support. METHODS: A subset of 503 patients participating in the ... Full text Link to item Cite

Exercise as a treatment for depression and other psychiatric disorders: a review.

Journal article J Cardiopulm Rehabil Prev · 2007 Featured Publication This article reviews evidence supporting exercise as a treatment for psychiatric disorders. Although data from randomized trials are limited, results of studies included in this review generally support use of exercise as an alternative or adjunctive treat ... Full text Link to item Cite

Exercise and pharmacotherapy in the treatment of major depressive disorder.

Journal article Psychosom Med · 2007 Featured Publication OBJECTIVE: To assess whether patients receiving aerobic exercise training performed either at home or in a supervised group setting achieve reductions in depression comparable to standard antidepressant medication (sertraline) and greater reductions in dep ... Full text Link to item Cite

Ventricular ectopy: impact of self-reported stress after myocardial infarction.

Journal article Am Heart J · January 2007 Featured Publication BACKGROUND: Although psychologic stress has been implicated in the pathogenesis of ventricular arrhythmias, the relationship between self-reported stress and ventricular ectopy has not been evaluated under naturalistic conditions in acute post-myocardial i ... Full text Link to item Cite

Understanding prognostic benefits of exercise and antidepressant therapy for persons with depression and heart disease: the UPBEAT study--rationale, design, and methodological issues.

Journal article Clin Trials · 2007 Featured Publication BACKGROUND: Depression is relatively common in patients with coronary heart disease (CHD) and is associated with worse prognosis. Recently there has been interest in evaluating the impact of treating depression on clinical outcomes. Anti-depressant medicat ... Full text Link to item Cite

Cerebrovascular risk factors, vascular disease, and neuropsychological outcomes in adults with major depression.

Journal article Psychosom Med · 2007 Featured Publication OBJECTIVE: To investigate the relationship of cerebrovascular risk factors (CVRFs), endothelial function, carotid artery intima medial thickness (IMT), and neuropsychological performance in a sample of 198 middle-aged and older individuals with major depre ... Full text Link to item Cite

Central nervous system injury associated with cardiac surgery.

Journal article Lancet · August 19, 2006 Featured Publication Millions of individuals with coronary artery or valvular heart disease have been given a new chance at life by heart surgery, but the potential for neurological injury is an Achilles heel. Technological advancements and innovations in surgical and anaesthe ... Full text Link to item Cite

Changes in plasma volume associated with mental stress ischemia in patients with coronary artery disease.

Journal article Int J Psychophysiol · August 2006 Featured Publication Psychological stress has been shown to trigger angina and myocardial ischemia in patients with coronary artery disease. However, the mechanisms by which stress may trigger cardiac events has yet to be fully elucidated. Twenty five patients underwent radion ... Full text Link to item Cite

Prediction of medical morbidity and mortality after acute myocardial infarction in patients at increased psychosocial risk in the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) study.

Journal article Am Heart J · July 2006 Featured Publication BACKGROUND: Patients with myocardial infarction (MI) are at further increased risk for untoward events when patients also exhibit low social support and/or depression. The ENRICHD study was the largest controlled trial in post-MI patients attempting to tre ... Full text Link to item Cite

Telephone-based coping skills training for patients awaiting lung transplantation.

Journal article J Consult Clin Psychol · June 2006 Featured Publication Impaired quality of life is associated with increased mortality in patients with advanced lung disease. Using a randomized controlled trial with allocation concealment and blinded outcome assessment at 2 tertiary care teaching hospitals, the authors random ... Full text Link to item Cite

Psychosocial issues in the assessment and management of patients undergoing lung transplantation.

Journal article Chest · May 2006 Featured Publication This review examines psychosocial issues among lung transplant patients from the time of assessment through the posttransplant period. Although psychological factors are recognized as being important in the transplant evaluation, no standard approach to ps ... Full text Link to item Cite

Successful bilateral lung transplant outcomes in recipients 61 years of age and older.

Journal article Transplantation · March 27, 2006 Featured Publication BACKGROUND: Controversy exists regarding the optimal use of bilateral lung transplant (BLT) in older recipients in diseases where either single or bilateral transplant is appropriate. International Society for Heart and Lung Transplant (ISHLT) guidelines s ... Full text Link to item Cite

Phobic anxiety, depression, and risk of ventricular arrhythmias in patients with coronary heart disease.

Journal article Psychosom Med · 2006 Featured Publication OBJECTIVE: Findings of an association between phobic anxiety and elevated risks of sudden cardiac death suggest that phobic anxiety may be related to increased risk of ventricular arrhythmias. The purpose of this study was to examine whether phobic anxiety ... Full text Link to item Cite

The effect of a psychosocial intervention and quality of life after acute myocardial infarction: the Enhancing Recovery in Coronary Heart Disease (ENRICHD) clinical trial.

Journal article J Cardiopulm Rehabil · 2006 Featured Publication PURPOSE: The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) clinical trial was designed to test whether intervening on depression or low perceived social support reduces mortality and reinfarction in patients with acute myocardial infarcti ... Full text Link to item Cite

Association of neurocognitive function and quality of life 1 year after coronary artery bypass graft (CABG) surgery.

Journal article Psychosom Med · 2006 Featured Publication OBJECTIVE: Although coronary artery bypass grafting (CABG) has been shown to improve quality of life and functional capacity for many patients, recent studies have demonstrated that a significant number of patients exhibit impairment in cognitive function ... Full text Link to item Cite

Association between hot flashes, sleep complaints, and psychological functioning among healthy menopausal women.

Journal article Int J Behav Med · 2006 Featured Publication Self-report data suggest that sleep hot flashes among menopausal women are associated with sleep problems and in turn impaired psychological functioning. However, few studies have examined these relations with physiologic hot flash measures. A total of 41 ... Full text Link to item Cite

Exercise training and depression in older adults.

Journal article Neurobiol Aging · December 2005 Featured Publication This article provides a review of the evidence supporting exercise as an effective treatment of depression in older adults. Depression is prevalent among older adults and is associated with significant morbidity, increased risk of mortality, and economic b ... Full text Link to item Cite

September 11, 2001, revisited: a review of the data.

Journal article Arch Surg · November 2005 Featured Publication HYPOTHESIS: The September 11, 2001, World Trade Center (WTC) attack was a disaster of epic proportion in New York City, NY. It was unprecedented in terms of the number of people who were killed in the bombings, as well as in terms of the volume of patients ... Full text Link to item Cite

Impaired endothelial function in coronary heart disease patients with depressive symptomatology.

Journal article J Am Coll Cardiol · August 16, 2005 Featured Publication OBJECTIVES: The purpose of this study was to assess whether depressive symptomatology was associated with vascular endothelial dysfunction in patients with coronary heart disease (CHD). BACKGROUND: In patients with CHD, the presence of depression is associ ... Full text Link to item Cite

Low heart rate variability and the effect of depression on post-myocardial infarction mortality.

Journal article Arch Intern Med · July 11, 2005 Featured Publication BACKGROUND: Depression is associated with an increased risk for mortality after acute myocardial infarction (MI). The purpose of this study was to determine whether low heart rate variability (HRV) mediates the effect of depression on mortality. METHODS: T ... Full text Link to item Cite

Effects of antidepressant medication on morbidity and mortality in depressed patients after myocardial infarction.

Journal article Arch Gen Psychiatry · July 2005 Featured Publication BACKGROUND: Depression after myocardial infarction (MI) is associated with higher morbidity and mortality. Although antidepressants are effective in reducing depression, their use in patients with cardiovascular disease remains controversial. OBJECTIVE: To ... Full text Link to item Cite

Emotional distress and quality of life in caregivers of patients awaiting lung transplant.

Journal article J Psychosom Res · July 2005 Featured Publication OBJECTIVE: The aims of this study are to characterize the levels of emotional distress and quality of life among caregivers of lung transplant candidates and to examine the relation of coping styles and perceived caregiver burden to caregivers' self-report ... Full text Link to item Cite

Depression and heart failure in patients with a new myocardial infarction.

Journal article Am Heart J · May 2005 Featured Publication BACKGROUND: Heart failure (HF) is a disabling chronic illness that is increasing in prevalence. Despite advances in its medical treatment, little is known about its psychosocial correlates. This investigation compared the prevalence of depression in patien ... Full text Link to item Cite

Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease: a randomized controlled trial.

Journal article JAMA · April 6, 2005 Featured Publication CONTEXT: Observational studies have shown that psychosocial factors are associated with increased risk for cardiovascular morbidity and mortality, but the effects of behavioral interventions on psychosocial and medical end points remain uncertain. OBJECTIV ... Full text Link to item Cite

The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology.

Journal article J Am Coll Cardiol · March 1, 2005 Featured Publication Observational studies indicate that psychologic factors strongly influence the course of coronary artery disease (CAD). In this review, we examine new epidemiologic evidence for the association between psychosocial risk factors and CAD, identify pathologic ... Full text Link to item Cite

Gas exchange and exercise capacity affect neurocognitive performance in patients with lung disease.

Journal article Psychosom Med · 2005 Featured Publication OBJECTIVE: This study examined the relationship between cognitive functioning and the severity of underlying lung disease in patients awaiting lung transplantation. METHODS: Ninety-four patients with end-stage lung disease completed a test battery to asses ... Full text Link to item Cite

Nonpharmacologic treatments for depression in patients with coronary heart disease.

Journal article Psychosom Med · 2005 Featured Publication OBJECTIVES: We review nonpharmacologic treatments for depression in patients with coronary heart disease (CHD), including psychological therapies such as cognitive behavior therapy (CBT) and interpersonal therapy (IPT), aerobic exercise, St. John's wort (S ... Full text Link to item Cite

Depression and cardiac risk.

Journal article J Cardiopulm Rehabil · 2005 Featured Publication Full text Link to item Cite

Social support and coronary heart disease: epidemiologic evidence and implications for treatment.

Journal article Psychosom Med · 2005 Featured Publication OBJECTIVE: The present paper reviews theories of social support and evidence for the role of social support in the development and progression of coronary heart disease (CHD). METHODS: Articles for the primary review of social support as a risk factor were ... Full text Link to item Cite

Emotional antecedents of hot flashes during daily life.

Journal article Psychosom Med · 2005 Featured Publication OBJECTIVE: Hot flashes are among the most frequently reported menopausal symptoms. However, little is known about factors associated with their occurrence. Moreover, despite the wide use of self-report hot flash measures, little is known about their concor ... Full text Link to item Cite

Social support and religiosity as coping strategies for anxiety in hospitalized cardiac patients.

Journal article Ann Behav Med · December 2004 Featured Publication BACKGROUND: Prospective studies have demonstrated that anxiety is associated with an increased risk of mortality and sudden cardiac death. There is therefore a need to understand what factors contribute to anxiety in patients with coronary heart disease (C ... Full text Link to item Cite

Fixing the heart: must the brain pay the price?

Journal article Circulation · November 30, 2004 Featured Publication Full text Link to item Cite

Association between exercise capacity and left ventricular geometry in overweight patients with mild systemic hypertension.

Journal article Am J Cardiol · November 15, 2004 Featured Publication The purpose of this study was to determine the relation between left ventricular (LV) geometry and exercise capacity in unmedicated, hypertensive patients. Analysis of the data revealed peak oxygen consumption (ml kg(-1) min(-1)) for concentric hypertrophy ... Full text Link to item Cite

Cognitive deficits following coronary artery bypass grafting: prevalence, prognosis, and therapeutic strategies.

Journal article CNS Spectr · October 2004 Featured Publication There is increasing recognition that coronary artery bypass grafting (CABG) may be a risk factor for subtle cognitive decline although the presence and pattern of such decline has varied across studies. Cognitive deficits may present as short-term memory l ... Full text Link to item Cite

Depression and anxiety symptoms are related to increased 24-hour urinary norepinephrine excretion among healthy middle-aged women.

Journal article J Psychosom Res · October 2004 Featured Publication OBJECTIVE: Depression is a risk factor for morbidity and mortality in a variety of populations, and anxiety has also been associated with risk of mortality among cardiac patients. Dysfunction of the autonomic nervous system may be involved in this risk. Th ... Full text Link to item Cite

Depression as a risk factor for post-MI mortality.

Journal article J Am Coll Cardiol · July 21, 2004 Featured Publication Full text Link to item Cite

Effects of daily stress on autonomic cardiac control in patients with coronary artery disease.

Journal article Am J Cardiol · May 15, 2004 Featured Publication Emotional stress has been implicated in the development and progression of coronary artery disease, with 1 proposed causal pathway being changes in cardiac autonomic tone. One hundred thirty-five patients with coronary artery disease underwent 48 hours of ... Full text Link to item Cite

Exercise, depression, and mortality after myocardial infarction in the ENRICHD trial.

Journal article Med Sci Sports Exerc · May 2004 Featured Publication PURPOSE: The large and well-characterized population of acute myocardial infarction (AMI) patients studied in the recently completed Enhancing Recovery in Coronary Heart Disease (ENRICHD) multicenter clinical trial provides a unique opportunity to examine ... Full text Link to item Cite

Health psychology: what will the future bring?

Journal article Health Psychol · March 2004 Featured Publication This commentary highlights several important themes and trends in this series of articles focusing on the future of health psychology. First, the challenges posed by changes in populations will only be met if health psychologists can develop a contextual c ... Full text Link to item Cite

Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients.

Journal article J Hypertens · February 2004 Featured Publication OBJECTIVE: To examine the association between the graded exercise systolic blood pressure (SBP) response and left ventricular (LV) geometric structure in patients with untreated mild hypertension. PARTICIPANTS: The study included 80 sedentary, overweight p ... Full text Link to item Cite

Depression and late mortality after myocardial infarction in the Enhancing Recovery in Coronary Heart Disease (ENRICHD) study.

Journal article Psychosom Med · 2004 Featured Publication OBJECTIVE: The Enhancing Recovery in Coronary Heart Disease study was a multicenter clinical trial in which patients with depression and/or low perceived social support after an acute myocardial infarction were randomly assigned to an intervention consisti ... Full text Link to item Cite

Effects of exercise, diet and weight loss on high blood pressure.

Journal article Sports Med · 2004 Featured Publication High blood pressure (BP) is a major health problem in the US, affecting more than 50 million people. Although high BP is among the most common reasons for outpatient visits, BP control is often inadequate. It is well established that BP can be lowered phar ... Full text Link to item Cite

Ethnic differences in left ventricular structure: relations to hemodynamics and diurnal blood pressure variation.

Journal article Am J Hypertens · January 2004 Featured Publication BACKGROUND: Previous studies have suggested that African Americans have a greater left ventricular relative wall thickness than whites with similar levels of blood pressure (BP), whereas other investigators have documented an attenuated nocturnal decline i ... Full text Link to item Cite

Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment.

Journal article Psychosom Med · 2004 Featured Publication OBJECTIVE: The present paper reviews the evidence that depression is a risk factor for the development and progression of coronary artery disease (CAD). METHODS: MEDLINE searches and reviews of bibliographies were used to identify relevant articles. Articl ... Full text Link to item Cite

Depression as a risk factor for mortality after acute myocardial infarction.

Journal article Am J Cardiol · December 1, 2003 Featured Publication The ENRICHD clinical trial, which compared an intervention for depression and social isolation to usual care, failed to decrease the rate of mortality and recurrent acute myocardial infarction (AMI) in post-AMI patients. One explanation for this is that de ... Full text Link to item Cite

Psychiatric disorder and quality of life in patients awaiting lung transplantation.

Journal article Chest · November 2003 Featured Publication STUDY OBJECTIVE: To examine the relationship between psychiatric comorbidity and quality of life in patients awaiting lung transplantation. SETTING: Duke University Medical Center/Lung Transplantation Program. PARTICIPANTS: One hundred patients with end-st ... Full text Link to item Cite

Effects of exercise and weight loss on cardiac risk factors associated with syndrome X.

Journal article Arch Intern Med · September 8, 2003 Featured Publication BACKGROUND: Patients with high blood pressure (BP) often exhibit syndrome X, an aggregation of abnormalities in carbohydrate and lipoprotein metabolism associated with increased risk of coronary heart disease (CHD). The present study evaluated the effects ... Full text Link to item Cite

Depression as a risk factor for mortality after coronary artery bypass surgery.

Journal article Lancet · August 23, 2003 Featured Publication BACKGROUND: Studies that have shown clinical depression to be a risk factor for cardiac events after coronary artery bypass graft (CABG) surgery have had small sample sizes, short follow-up, and have not had adequate power to assess mortality. We sought to ... Full text Link to item Cite

Effects of exercise and weight loss on hypertension.

Journal article JAMA · August 20, 2003 Featured Publication Full text Link to item Cite

Cognitive and somatic symptoms of depression are associated with medical comorbidity in patients after acute myocardial infarction.

Journal article Am Heart J · July 2003 Featured Publication BACKGROUND: Depression is common in patients with acute myocardial infarction (AMI) and is associated with adverse health outcomes. However, the extent to which clinical depression is related to comorbid medical conditions is unknown. This study examined t ... Full text Link to item Cite

Depression and increased myocardial ischemic activity in patients with ischemic heart disease.

Journal article Am Heart J · July 2003 Featured Publication BACKGROUND: Depression is relatively common in patients with ischemic heart disease (IHD) and is associated with increased risk of mortality and morbidity. However, the mechanisms by which depression adversely affects clinical outcomes of patients with IHD ... Full text Link to item Cite

Chronic exposure to nicotine does not prevent neurocognitive decline after cardiac surgery.

Journal article J Cardiothorac Vasc Anesth · June 2003 Featured Publication OBJECTIVE: To establish the association between smoking and cognitive decline in patients undergoing coronary artery bypass graft (CABG) surgery. DESIGN: Retrospective review. SETTING: Referral center for cardiothoracic surgery at a university hospital. PA ... Full text Link to item Cite

Depression and ischemic heart disease: overview of the evidence and treatment implications.

Journal article Curr Psychiatry Rep · May 2003 Featured Publication In this article, the authors review the evidence that depression is a risk factor for ischemic heart disease and examine the efficacy and safety of depression treatments in patients with ischemic heart disease. ... Full text Link to item Cite

Lower endotoxin immunity predicts increased cognitive dysfunction in elderly patients after cardiac surgery.

Journal article Stroke · February 2003 Featured Publication BACKGROUND AND PURPOSE: Although coronary artery bypass graft surgery (CABG) improves the quality of life and functional capacity for numerous patients, many also exhibit impairment in cognitive function immediately after surgery. Although the etiology of ... Full text Link to item Cite

Female gender is associated with impaired quality of life 1 year after coronary artery bypass surgery.

Journal article Psychosom Med · 2003 Featured Publication OBJECTIVE: To evaluate gender-related differences in quality of life (QOL) and cognitive function 1 year after coronary artery bypass surgery (CABG) after adjusting for known baseline differences. MATERIALS AND METHODS: Two hundred eighty patients (96 wome ... Full text Link to item Cite

Hostility, social support, and adrenergic receptor responsiveness among African-American and white men and women.

Journal article Psychosom Med · 2003 Featured Publication OBJECTIVE: We examined the relationship between beta-adrenergic receptor responsiveness and hostility and social support in African American and white men and women. METHODS: The participants were 149 men and women, aged 25 to 45 years with SBP < 160 and D ... Full text Link to item Cite

Exercise therapy for depression in middle-aged and older adults: predictors of early dropout and treatment failure.

Journal article Health Psychol · November 2002 Featured Publication Psychosocial factors predicting treatment dropout or failure to benefit from treatment were identified in a randomized trial of exercise therapy and pharmacotherapy for major depression. One hundred fifty-six men and women over age 50 diagnosed with major ... Link to item Cite

Effects of a telephone-based psychosocial intervention for patients awaiting lung transplantation.

Journal article Chest · October 2002 Featured Publication STUDY OBJECTIVES: To test the efficacy of a tailored telephone-based intervention consisting of supportive counseling and cognitive behavioral techniques for individuals awaiting lung transplantation on measures of quality of life and general well-being. M ... Full text Link to item Cite

Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction.

Other Anesth Analg · July 2002 Featured Publication UNLABELLED: Renal dysfunction is common after coronary artery bypass graft (CABG) surgery. We have previously shown that CABG procedures complicated by stroke have a threefold greater peak serum creatinine level relative to uncomplicated surgery. However, ... Full text Link to item Cite

Reduction of left ventricular hypertrophy after exercise and weight loss in overweight patients with mild hypertension.

Journal article Arch Intern Med · June 24, 2002 Featured Publication BACKGROUND: Hypertrophy and concentric remodeling of the left ventricle are important manifestations of hypertension that are associated with increased morbidity and mortality. Although lifestyle interventions are efficacious in lowering blood pressure, ev ... Full text Link to item Cite

Biobehavioral approaches to the treatment of essential hypertension.

Journal article J Consult Clin Psychol · June 2002 Featured Publication Despite recent advances in the medical management of hypertension, chronically elevated blood pressure remains a major health problem in the United States, affecting almost 50 million Americans. It is widely recognized that lifestyle factors contribute to ... Link to item Cite

Changes in hemodynamics and left ventricular structure after menopause.

Journal article Am J Cardiol · April 1, 2002 Featured Publication To evaluate the cardiovascular changes associated with menopause, we studied hemodynamics at rest, ambulatory blood pressure, and left ventricular structure in a biracial cohort of pre- and postmenopausal women of similar age, race, weight, and blood press ... Full text Link to item Cite

Association of anxiety with reduced baroreflex cardiac control in patients after acute myocardial infarction.

Journal article Am Heart J · March 2002 Featured Publication BACKGROUND: Although depression has been associated with increased mortality in patients after acute myocardial infarction (AMI), little is known about the effects of depression on autonomic nervous system control of heart rate. This study evaluated whethe ... Full text Link to item Cite

Nighttime blood pressure dipping: the role of the sympathetic nervous system.

Journal article Am J Hypertens · February 2002 Featured Publication There is a marked diurnal variation in blood pressure (BP), with BP dipping to its lowest levels during nighttime sleep. A day-night dip in systolic BP (SBP) of <10% has been used to characterize individuals as nondippers, and is associated with an increas ... Full text Link to item Cite

The impact of postoperative atrial fibrillation on neurocognitive outcome after coronary artery bypass graft surgery.

Journal article Anesth Analg · February 2002 Featured Publication UNLABELLED: Neurocognitive decline is a continuing source of morbidity after cardiac surgery. Atrial fibrillation occurs often after cardiac surgery and has been linked to adverse neurologic events. We sought to determine whether postoperative atrial fibri ... Full text Link to item Cite

Usefulness of psychosocial treatment of mental stress-induced myocardial ischemia in men.

Journal article Am J Cardiol · January 15, 2002 Featured Publication This study examined the effects of exercise and stress management training on clinical outcomes and medical expenditures over a 5-year follow-up period in 94 male patients with established coronary artery disease (CAD) and evidence of ambulatory or mental ... Full text Link to item Cite

The rewarming rate and increased peak temperature alter neurocognitive outcome after cardiac surgery.

Other Anesth Analg · January 2002 Featured Publication UNLABELLED: Neurocognitive dysfunction is a common complication after cardiac surgery. We evaluated in this prospective study the effect of rewarming rate on neurocognitive outcome after hypothermic cardiopulmonary bypass (CPB). After IRB approval and info ... Full text Link to item Cite

Exercise and the treatment of clinical depression in adults: recent findings and future directions.

Journal article Sports Med · 2002 Featured Publication This article critically reviews the evidence that exercise is effective in treating depression in adults. Depression is recognised as a mood state, clinical syndrome and psychiatric condition, and traditional methods for assessing depression (e.g. standard ... Full text Link to item Cite

Relationship of clinic, ambulatory, and laboratory stress blood pressure to left ventricular mass in overweight men and women with high blood pressure.

Journal article Psychosom Med · 2002 Featured Publication OBJECTIVE: This study was designed to evaluate the relationship between left ventricular (LV) mass and blood pressure (BP) recorded in the following contexts: in the clinic, using standard auscultatory procedures, during a typical day using ambulatory BP m ... Full text Link to item Cite

Report of the substudy assessing the impact of neurocognitive function on quality of life 5 years after cardiac surgery.

Journal article Stroke · December 1, 2001 Featured Publication BACKGROUND AND PURPOSE: The importance of perioperative cognitive decline has long been debated. We recently demonstrated a significant correlation between perioperative cognitive decline and long-term cognitive dysfunction. Despite this association, some ... Full text Link to item Cite

Prospective randomized trial of normothermic versus hypothermic cardiopulmonary bypass on cognitive function after coronary artery bypass graft surgery.

Journal article Anesthesiology · November 2001 Featured Publication BACKGROUND: Despite significant advances in cardiopulmonary bypass (CPB) technology, surgical techniques, and anesthetic management, central nervous system complications occur in a large percentage of patients undergoing surgery requiring CPB. Many centers ... Full text Link to item Cite

Depression, heart rate variability, and acute myocardial infarction.

Journal article Circulation · October 23, 2001 Featured Publication BACKGROUND: Clinical depression is associated with an increased risk for mortality in patients with a recent myocardial infarction (MI). Reduced heart rate variability (HRV) has been suggested as a possible explanation for this association. The purpose of ... Full text Link to item Cite

Effects of exercise and weight loss on blood pressure during daily life.

Journal article Med Sci Sports Exerc · October 2001 Featured Publication PURPOSE: The objective of this study was to investigate the effects of exercise training and weight loss on blood pressure (BP) associated with physical activity and emotional stress during daily life. METHODS: One hundred twelve participants with unmedica ... Full text Link to item Cite

Binge eating disorder and night eating syndrome: psychological and behavioral characteristics.

Journal article Int J Eat Disord · September 2001 Featured Publication OBJECTIVE: The present study was designed to examine the psychological and behavioral characteristics associated with both night eating syndrome (NES) and binge eating disorder (BED) in 42 males and 41 females who were enrolled in a university-based weight ... Full text Link to item Cite

Blunted nighttime blood pressure dipping in postmenopausal women.

Journal article Am J Hypertens · August 2001 Featured Publication Blunting of the normal drop in blood pressure (BP) from day to night is emerging as a strong prognostic indicator of cardiovascular morbidity and mortality. This study evaluated the effects of natural menopause on BP dipping in African American and white w ... Full text Link to item Cite

Linkages between facial expressions of anger and transient myocardial ischemia in men with coronary artery disease.

Journal article Emotion · June 2001 Featured Publication The authors examined whether facial expressions of emotion would predict changes in heart function. One hundred fifteen male patients with coronary artery disease underwent the Type A Structured Interview, during which time measures of transient myocardial ... Full text Link to item Cite

Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery.

Journal article N Engl J Med · February 8, 2001 Featured Publication BACKGROUND: Cognitive decline complicates early recovery after coronary-artery bypass grafting (CABG) and may be evident in as many as three quarters of patients at the time of discharge from the hospital and a third of patients after six months. We sought ... Full text Link to item Cite

Religious coping, ethnicity, and ambulatory blood pressure.

Journal article Psychosom Med · 2001 Featured Publication OBJECTIVE: To investigate the relationship between religious coping, ethnicity, and ambulatory blood pressure (ABP) measured during daily life. METHODS: A 24-hour ABP was obtained from 155 men and women (78 African American and 77 white) on a typical workd ... Full text Link to item Cite

Psychosocial characteristics after acute myocardial infarction: the ENRICHD pilot study. Enhancing Recovery in Coronary Heart Disease.

Journal article J Cardiopulm Rehabil · 2001 Featured Publication PURPOSE: Psychosocial factors, such as emotional distress and social isolation, have been increasingly recognized as important risk factors for patients' recovery from acute myocardial infarction (AMI). This study examined age, gender, and ethnic differenc ... Full text Link to item Cite

Temperature during coronary artery bypass surgery affects quality of life.

Journal article Ann Thorac Surg · January 2001 Featured Publication BACKGROUND: The objective of this study was to examine the effects of temperature on a variety of indices of psychologic adjustment and quality of life. METHODS: A total of 209 patients randomly received normothermic (warm) or hypothermic (cold) conditions ... Full text Link to item Cite

Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure.

Journal article Hypertension · August 2000 Featured Publication The purpose of this study was to determine the effects of exercise and weight loss on cardiovascular responses during mental stress in mildly to moderately overweight patients with elevated blood pressure. Ninety-nine men and women with high normal or unme ... Full text Link to item Cite

Exercise and weight loss reduce blood pressure in men and women with mild hypertension: effects on cardiovascular, metabolic, and hemodynamic functioning.

Journal article Arch Intern Med · July 10, 2000 Featured Publication BACKGROUND: Lifestyle modifications have been recommended as the initial treatment strategy for lowering high blood pressure (BP). However, evidence for the efficacy of exercise and weight loss in the management of high BP remains controversial. METHODS: O ... Full text Link to item Cite

Emotional responsivity during daily life: relationship to psychosocial functioning and ambulatory blood pressure.

Journal article Int J Psychophysiol · April 2000 Featured Publication Emotional responsivity refers to acute changes in affective states. This study examined the relationship of emotional responsivity during daily life with ambulatory blood pressure (ABP) and psychosocial functioning. Subjects were 162 employed men and women ... Full text Link to item Cite

Ambulatory blood pressure and marital distress in employed women.

Journal article Behav Med · 2000 Featured Publication In this investigation, the relationship between marital distress and blood pressure during daily life in a sample of married employed women was examined. It was hypothesized that greater marital distress would be associated with elevated blood pressure in ... Full text Link to item Cite

Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months.

Journal article Psychosom Med · 2000 Featured Publication OBJECTIVE: The purpose of this study was to assess the status of 156 adult volunteers with major depressive disorder (MDD) 6 months after completion of a study in which they were randomly assigned to a 4-month course of aerobic exercise, sertraline therapy ... Full text Link to item Cite

Cognitive decline after major noncardiac operations: a preliminary prospective study.

Journal article Ann Thorac Surg · November 1999 Featured Publication BACKGROUND: Cardiac operations frequently are complicated by postoperative cognitive decline. Less common and less studied is postoperative cognitive decline after noncardiac surgery, so we determined its incidence, severity, and possible predictors. METHO ... Full text Link to item Cite

Effects of exercise training on older patients with major depression.

Journal article Arch Intern Med · October 25, 1999 Featured Publication BACKGROUND: Previous observational and interventional studies have suggested that regular physical exercise may be associated with reduced symptoms of depression. However, the extent to which exercise training may reduce depressive symptoms in older patien ... Full text Link to item Cite

Worried to death?

Journal article Circulation · September 14, 1999 Featured Publication Link to item Cite

Emotional responsivity and transient myocardial ischemia.

Journal article J Consult Clin Psychol · August 1999 Featured Publication This study examined the relationship between "emotional responsivity" (i.e., individuals who exhibit relatively large variations of self-reported tension levels) and myocardial ischemia. One hundred thirty-six patients with coronary artery disease underwen ... Full text Link to item Cite

Perception of cognitive function in older adults following coronary artery bypass surgery.

Journal article Health Psychol · May 1999 Featured Publication This study examined the effects of coronary artery bypass grafting (CABG) on objective and subjective measures of neurocognitive functioning. Participants were 170 older patients (127 men and 43 women; mean age = 61 years) undergoing CABG. Measures of neur ... Full text Link to item Cite

Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy.

Journal article Circulation · April 27, 1999 Featured Publication Recent studies provide clear and convincing evidence that psychosocial factors contribute significantly to the pathogenesis and expression of coronary artery disease (CAD). This evidence is composed largely of data relating CAD risk to 5 specific psychosoc ... Full text Link to item Cite

Mental stress and coronary disease. The Smart-Heart Study.

Journal article N C Med J · 1999 Featured Publication Link to item Cite

Anxiety reduces baroreflex cardiac control in older adults with major depression.

Journal article Psychosom Med · 1999 Featured Publication OBJECTIVE: Although depression and anxiety predict risk of cardiac mortality, the contributions of depression and anxiety to vagal cardiac control have not been systematically evaluated. The goal of this study was to examine the relationship between state ... Full text Link to item Cite

Predicting peak oxygen uptake among older patients with chronic illness.

Journal article J Cardiopulm Rehabil · 1999 Featured Publication PURPOSE: To compare three equations developed to predict VO2 among patients diagnosed with one of two chronic diseases: essential hypertension (HTN), and fibromyalgia (FM). The equations included the American College of Sports Medicine (ACSM) equation, the ... Full text Link to item Cite

Endothelial function and hemodynamic responses during mental stress.

Journal article Psychosom Med · 1999 Featured Publication OBJECTIVE: The hemodynamic basis of blood pressure responses during psychological stress shows striking individual differences that share an interesting similarity with risk for cardiovascular disease. Factors accounting for these individual differences ar ... Full text Link to item Cite

Facial expression and the affective component of cynical hostility in male coronary heart disease patients.

Journal article Health Psychol · July 1998 Featured Publication This study describes the affective component of hostility as measured by the Cook-Medley Hostility Scale (Ho; W. Cook & D. Medley, 1954) by examining the relationship between facial expressions of emotion and Ho scores in 116 male coronary heart disease pa ... Full text Link to item Cite

Psychosocial influences on blood pressure during daily life.

Journal article Int J Psychophysiol · March 1998 Featured Publication Ambulatory blood pressure (ABP) monitoring allows frequent non-invasive blood pressure (BP) recordings in a variety of settings. Emerging evidence suggests that ABP is a better predictor of cardiovascular morbidity than clinic BP. Ambulatory blood pressure ... Full text Link to item Cite

The reasonable woman standard: a meta-analytic review of gender differences in perceptions of sexual harassment.

Journal article Law Hum Behav · February 1998 Featured Publication Courts and legislatures have begun to develop the "reasonable woman standard" (RWS) as a criterion for deciding sexual harassment trials. This standard rests on assumptions of a "wide divergence" between the perceptions of men and women when viewing social ... Full text Link to item Cite

Muscarinic inhibition of substance P induced ion secretion in piglet jejunum.

Journal article Can J Physiol Pharmacol · February 1998 Featured Publication We examined the effects of the muscarinic agonist carbachol on ion secretion induced by substance P (SP) in piglet jejunal tissues mounted in Ussing chambers. Tetrodotoxin was present in all solutions to inhibit neural activity. Carbachol added 10 min prio ... Link to item Cite

High anxiety and white coat hypertension.

Journal article JAMA · January 21, 1998 Featured Publication Full text Link to item Cite

Interaction of hypertension and age in visual selective attention performance.

Journal article Health Psychol · January 1998 Featured Publication Previous research suggests that some aspects of cognitive performance decline as a joint function of age and hypertension. In this experiment, 51 unmedicated individuals with mild essential hypertension and 48 normotensive individuals, 18-78 years of age, ... Full text Link to item Cite

Blood pressure reactivity and marital distress in employed women.

Journal article Psychosom Med · 1998 Featured Publication OBJECTIVE: The impact of marital distress on cardiovascular responses to an "ecologically valid" laboratory stressor (a marital conflict recall task) was examined in maritally distressed and non-distressed women. It was hypothesized that the presence of hi ... Full text Link to item Cite

Exercise training as an alternative treatment for depression among older adults.

Journal article Altern Ther Health Med · January 1998 Featured Publication This article reviews the current literature related to exercise treatment and depression among older adults. Results from investigational studies support the antidepressive effects of exercise programs. Aerobic exercise is more effective than placebo or no ... Link to item Cite

Effect of satisfaction with social support on blood pressure in normotensive and borderline hypertensive men and women.

Journal article Int J Behav Med · 1998 Featured Publication The relation between blood pressure (BP) and two aspects of social support, perceived satisfaction and structural social support network characteristics, were examined in adults classified as having normal BP or borderline hypertension. Causal BPs were tak ... Full text Link to item Cite

Cognitive function 5 years after randomization to coronary angioplasty or coronary artery bypass graft surgery.

Journal article Circulation · November 4, 1997 Featured Publication BACKGROUND: Coronary bypass surgery often leads to short-term cognitive dysfunction, whereas coronary angioplasty does not. Perioperative cognitive dysfunction usually resolves, although a subgroup of surgical patients may continue to exhibit long-term cog ... Link to item Cite

Stress management and exercise training in cardiac patients with myocardial ischemia. Effects on prognosis and evaluation of mechanisms.

Journal article Arch Intern Med · October 27, 1997 Featured Publication BACKGROUND: Previous studies have demonstrated that myocardial ischemia can be elicited by mental stress in the laboratory and during daily life and that ischemia induced by mental stress is associated with an increased risk for future cardiac events in pa ... Link to item Cite

Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center.

Other Ann Thorac Surg · September 1997 Featured Publication BACKGROUND: Changes in memory and cognition frequently follow cardiac operations. We hypothesized that patients with the apolipoprotein E-epsilon 4 allele are genetically predisposed to cognitive dysfunction after cardiac operations. METHODS: The apolipopr ... Full text Link to item Cite

Defining dysfunction: group means versus incidence analysis--a statement of consensus.

Journal article Ann Thorac Surg · September 1997 Featured Publication Full text Link to item Cite

Stability over time of circadian rhythm of variability of heart rate in patients with stable coronary artery disease.

Journal article Am Heart J · September 1997 Featured Publication Reproducibility of circadian rhythm of variability in heart rate was studied in 40 patients with stable coronary artery disease who underwent 48-hour ambulatory electrocardiographic recordings at baseline (time 1) and after 4 months (time 2). The standard ... Full text Link to item Cite

Psychosocial correlates of job strain in a sample of working women.

Journal article Arch Gen Psychiatry · June 1997 Featured Publication BACKGROUND: This study identifies potential mediators of job strain effects on health by determining whether psychosocial factors known to predict an increased risk of cardiovascular disease and all-cause mortality are higher among women who report high le ... Full text Link to item Cite

Effects of mental stress on myocardial ischemia during daily life.

Journal article JAMA · May 21, 1997 Featured Publication OBJECTIVE: To determine the relative risk of myocardial ischemia triggered by specific emotions during daily life. DESIGN AND SETTING: Relative risk was calculated by the recently developed case-crossover method, in which the frequency of a presumed trigge ... Link to item Cite

Personality factors differentially predict exercise behavior in men and women.

Journal article Womens Health · 1997 Featured Publication Personality assessed with the Minnesota Multiphasic Personality Inventory (MMPI) in college was used to predict exercise behavior measured at midlife in 3,630 men and 796 women enrolled in the University of North Carolina Alumni Heart Study. Logistic regre ... Link to item Cite

Psychosocial factors and coronary disease. A national multicenter clinical trial (ENRICHD) with a North Carolina focus.

Journal article N C Med J · 1997 Featured Publication In addition to traditional risk factors (cigarette smoking, high blood pressure, and elevated cholesterol) psychosocial factors (depression, social isolation, and low socioeconomic status) have an adverse impact on prognosis of patients with CAD. Several s ... Link to item Cite

Relation of mood ratings and neurohormonal responses during daily life in employed women.

Journal article Int J Behav Med · 1997 Featured Publication Diurnal variations in urinary norepinephrine, epinephrine, cortisol, and self-reported mood states were examined in 101 employed women. Urine was collected on 2 consecutive workdays at 3 time periods: (1) overnight, (2) daytime, and (3) evening. Self-repor ... Full text Link to item Cite

Stress in employed women: impact of marital status and children at home on neurohormone output and home strain.

Journal article Psychosom Med · 1997 Featured Publication OBJECTIVE: To evaluate the biological and psychological effects of role overload, we examined the effects of marital (or partnership) status and parental status (defined as having children at home) on daily excretion of urinary catecholamines and cortisol ... Full text Link to item Cite

Pain in arthritis and musculoskeletal disorders: the role of coping skills training and exercise interventions.

Journal article J Orthop Sports Phys Ther · October 1996 Featured Publication There is growing recognition of the limitations of conventional, biomedical approaches to the management of pain in individuals having arthritis and musculoskeletal disorders. This article provides an overview of newly developed biopsychosocial approaches ... Full text Link to item Cite

Depression and long-term mortality risk in patients with coronary artery disease.

Journal article Am J Cardiol · September 15, 1996 Featured Publication Previous research has established that patients with coronary artery disease (CAD) have an increased risk of death if they are depressed at the time of hospitalization. Follow-up periods have been short in these studies; therefore, the present investigatio ... Full text Link to item Cite

Is the target income hypothesis an economic heresy?

Journal article Med Care Res Rev · September 1996 Featured Publication Full text Link to item Cite

Mental stress--induced myocardial ischemia and cardiac events.

Journal article JAMA · June 5, 1996 Featured Publication OBJECTIVE: To assess the clinical significance of mental stress-induced myocardial ischemia in patients with coronary artery disease (CAD). DESIGN AND SETTING: Cohort study in outpatients in a tertiary care teaching hospital assessed at baseline and follow ... Full text Link to item Cite

Defining neuropsychological dysfunction after coronary artery bypass grafting.

Journal article Ann Thorac Surg · May 1996 Featured Publication BACKGROUND: Despite the large body of literature documenting the presence of cognitive decline after coronary artery bypass grafting, there is little consensus as to the frequency and extent of cognitive impairment. One potential reason for this lack of ag ... Full text Link to item Cite

Mental stress-induced ischemia in the laboratory and ambulatory ischemia during daily life. Association and hemodynamic features.

Journal article Circulation · October 15, 1995 Featured Publication BACKGROUND: The purpose of this study was to determine the correspondence of mental stress-induced ischemia in the laboratory with ambulatory ischemia and to assess the relationship between hemodynamic responses to mental stress and the occurrence of ische ... Full text Link to item Cite

Cardiac rehabilitation as secondary prevention. Agency for Health Care Policy and Research and National Heart, Lung, and Blood Institute.

Journal article Clin Pract Guidel Quick Ref Guide Clin · October 1995 Featured Publication This Quick Reference Guide for Clinicians highlights the conclusions and recommendations from Cardiac Rehabilitation, Clinical Practice Guideline No. 17, which was formulated by a panel representing the major health care disciplines involved in cardiac reh ... Link to item Cite

Relative importance of electrode placement over number of channels in transient myocardial ischemia detection by Holter monitoring.

Journal article Am J Cardiol · August 15, 1995 Featured Publication To compare the efficacy of 3-channel ambulatory electrocardiographic monitoring (Holter monitoring) with 2-channel Holter monitoring in the detection of transient myocardial ischemia (TMI), channels CM2, CM5, and modified II were studied. Sixty patients wi ... Full text Link to item Cite

Differential age effects of mean arterial pressure and rewarming on cognitive dysfunction after cardiac surgery.

Journal article Anesth Analg · August 1995 Featured Publication Central nervous system dysfunction is a common consequence of otherwise uncomplicated cardiac surgery. Many mechanisms have been postulated for the cognitive dysfunction that is part of these neurologic sequelae. The purpose of our investigation was to eva ... Full text Link to item Cite

Ethnic differences in hemodynamic responses to stress in hypertensive men and women.

Journal article Am J Hypertens · June 1995 Featured Publication Hemodynamic response patterns to three laboratory stressors were compared in 63 mildly hypertensive black and white men and women. Ethnic groups were matched for age, body mass index, and casual blood pressures. Stressors included a mental arithmetic task, ... Full text Link to item Cite

Distinguishing between early and late responders to symptoms of acute myocardial infarction.

Journal article Am J Cardiol · May 15, 1995 Featured Publication The present study identified factors that distinguish early responders (i.e., requested medical assistance < 60 minutes after the onset of acute myocardial infarction [AMI] symptoms) from late responders (i.e., request made > or = 60 minutes after symptom ... Full text Link to item Cite

Predictors of cognitive decline after cardiac operation.

Journal article Ann Thorac Surg · May 1995 Featured Publication Despite major advances in cardiopulmonary bypass technology, surgical techniques, and anesthesia management, central nervous system complications remain a common problem after cardiopulmonary bypass. The etiology of neuropsychologic dysfunction after cardi ... Full text Link to item Cite

Methodological issues in the assessment of neuropsychologic function after cardiac surgery.

Journal article Ann Thorac Surg · May 1995 Featured Publication This report reviews critical issues facing investigators interested in neuropsychologic sequelae after cardiac operations: (1) experimental design; (2) selective attrition; (3) selection of instruments; (4) moderating factors; (5) definitions of cognitive ... Full text Link to item Cite

Depression in male and female patients undergoing cardiac surgery.

Journal article Br J Clin Psychol · February 1995 Featured Publication The present longitudinal study was designed to determine the prevalence of depression in male and female patients undergoing cardiac surgery, and to examine what factors are associated with depression before and after surgery. One day prior to surgery (T1) ... Full text Link to item Cite

Contribution of job strain, job status and marital status to laboratory and ambulatory blood pressure in patients with mild hypertension.

Journal article J Psychosom Res · February 1995 Featured Publication The effects of job strain, occupational status, and marital status on blood pressure were evaluated in 99 men and women with mild hypertension. Blood pressure was measured during daily life at home and at work over 15 h of ambulatory blood pressure monitor ... Full text Link to item Cite

Do exercise and weight loss reduce blood pressure in patients with mild hypertension?

Journal article N C Med J · February 1995 Featured Publication We conclude from our review that exercise and weight loss offer some promise as non-pharmacologic treatments for hypertension. Unfortunately, most available studies are methodologically unsound, and the mechanisms by which exercise lowers blood pressure ar ... Link to item Cite

Family history of hypertension influences neurobehavioral function in hypertensive patients.

Journal article Psychosom Med · 1995 Featured Publication This study examined the influence of family history of hypertension on neurobehavioral performance. Sixty-two hypertensive men and women who reported a family history of hypertension (+FH) were compared with 28 hypertensive individuals without a family his ... Full text Link to item Cite

The Mini Mental State Exam as a predictor of neuropsychological functioning after cardiac surgery.

Journal article Int J Psychiatry Med · 1995 Featured Publication OBJECTIVE: The present longitudinal study was designed to: 1) determine the ability of the Mini Mental State Exam (MMSE) to predict neuropsychologic impairment based on neuropsychologic testing five to seven days and six weeks after cardiac surgery; and 2) ... Full text Link to item Cite

Association of physical fitness and transient myocardial ischemia in patients with coronary artery disease.

Journal article J Cardiopulm Rehabil · 1995 Featured Publication PURPOSE: To examine the relationship between physical fitness and transient myocardial ischemia (TMI) in the laboratory and during daily life, in a sample of coronary patients with a recent positive exercise test. METHODS: 47 patients with coronary disease ... Full text Link to item Cite

Jugular bulb saturation and cognitive dysfunction after cardiopulmonary bypass.

Journal article Ann Thorac Surg · December 1994 Featured Publication Inadequate cerebral oxygenation during cardiopulmonary bypass may lead to postoperative cognitive dysfunction in patients undergoing cardiac operations. A psychological test battery was administered to 255 patients before cardiac operation and just before ... Full text Link to item Cite

Effect of aging on cerebral autoregulation during cardiopulmonary bypass. Association with postoperative cognitive dysfunction.

Journal article Circulation · November 1994 Featured Publication BACKGROUND: Age is a predictor of cognitive dysfunction after cardiac surgery, but the mechanism is unknown. The purpose of our study was to determine whether age-related decrements in cognition are associated with cerebral blood flow (CBF) autoregulation ... Link to item Cite

Quality of life and recovery after cardiac surgery.

Journal article Psychosom Med · 1994 Featured Publication Full text Link to item Cite

Serum lipids, neuroendocrine, and cardiovascular responses to stress in men and women with mild hypertension.

Journal article Behav Med · 1994 Featured Publication In this study, we examined the relation between serum lipid levels, gender, and cardiovascular and neuroendocrine stress reactivity in patients with mild hypertension. Ninety-nine individuals (62 men, 37 women) with mild hypertension performed four mental ... Full text Link to item Cite

Relation of cardiovascular responses to mental stress and cardiac vagal activity in coronary artery disease.

Journal article Am J Cardiol · September 1, 1993 Featured Publication Forty-six patients with documented coronary artery disease were studied to examine the relation of cardiovascular reactivity to mental stress and cardiac vagal activity. Cardiac vagal activity was measured by means of frequency-domain analysis of heart rat ... Full text Link to item Cite

Effects of aerobic exercise on cognitive and psychosocial functioning in patients with mild hypertension.

Journal article Health Psychol · July 1993 Featured Publication The effects of 16 weeks of physical exercise training on the psychological functioning of 90 patients with mild hypertension were examined. At baseline and after 16 weeks of training, patients completed a psychometric test battery that included objective m ... Full text Link to item Cite

Psychobehavioral treatment in cardiac rehabilitation.

Journal article Cardiol Clin · May 1993 Featured Publication This article reviews the empirical evidence for the use of behavioral and psychological therapies in the rehabilitation of patients with coronary disease. Exercise training, Type A modification, psychological counseling, smoking cessation, and dietary modi ... Link to item Cite

The effects of aerobic exercise on premenstrual symptoms in middle-aged women: a preliminary study.

Journal article J Psychosom Res · 1993 Featured Publication The effects of aerobic exercise and strength training on premenstrual symptoms were evaluated in 23 healthy premenopausal women. Premenstrual symptoms were assessed at baseline and following 3 months of exercise participation. Women who engaged in aerobic ... Full text Link to item Cite

Hypertension affects neurobehavioral functioning.

Journal article Psychosom Med · 1993 Featured Publication This study compared the neurobehavioral performance of hypertensive and normotensive men and women using neuropsychological, information-processing, and psychometric assessments. One hundred subjects, including 68 hypertensive and 32 normotensive individua ... Full text Link to item Cite

Serum lipids, neuroendocrine and cardiovascular responses to stress in healthy Type A men.

Journal article Biol Psychol · October 1992 Featured Publication This study examined the relationship between serum lipid activity in healthy Type A men and cardiovascular and neuroendocrine responses to a behavioral stressor, mental arithmetic. Assessment of blood lipids included measures of total cholesterol (TC), low ... Full text Link to item Cite

Obsessive and compulsive traits in athletes.

Journal article Sports Med · October 1992 Featured Publication Full text Link to item Cite

Exercise adherence or maintenance among older adults: 1-year follow-up study.

Journal article Psychol Aging · September 1992 Featured Publication Follow-up evaluation was conducted of 101 older men and women (mean age = 67 +/- 5 years) who had participated in a randomized study of physiological and psychological effects of aerobic exercise. Eighty-five subjects completed the follow-up evaluation, an ... Full text Link to item Cite

Warming during cardiopulmonary bypass is associated with jugular bulb desaturation.

Journal article Ann Thorac Surg · May 1992 Featured Publication The objective of this study was to characterize cerebral venous effluent during normothermic nonpulsatile cardiopulmonary bypass. Thirty-one (23%) of 133 patients met desaturation criteria (defined as jugular bulb venous oxygen saturation less than or equa ... Full text Link to item Cite

Long-term effects of exercise on psychological functioning in older men and women.

Journal article J Gerontol · November 1991 Featured Publication The purpose of this study was to determine the psychological, behavioral, and cognitive changes associated with up to 14 months of aerobic exercise training. For the first 4 months of the study, 101 older (greater than 60 years) men and women were randomly ... Full text Link to item Cite

Effects of exercise training on bone density in older men and women.

Journal article J Am Geriatr Soc · November 1991 Featured Publication OBJECTIVES: To determine the effects of up to 14 months of aerobic exercise on measures of bone density in older adults. DESIGN: Randomized controlled trial with subjects assigned to either an aerobic exercise condition, non-aerobic yoga, or a wait list no ... Full text Link to item Cite

Failure of exercise to reduce blood pressure in patients with mild hypertension. Results of a randomized controlled trial.

Journal article JAMA · October 16, 1991 Featured Publication OBJECTIVE: --To assess the effects of physical exercise training on blood pressure in patients with mild hypertension. DESIGN: --Randomized controlled trial. SETTING: --Hospital-based cardiac rehabilitation program. PATIENTS: --Ninety-nine men and women wi ... Link to item Cite

Effects of exercise training on cardiorespiratory function in men and women older than 60 years of age.

Journal article Am J Cardiol · March 15, 1991 Featured Publication This study reports the physiologic effects of up to 14 months of aerobic exercise in 101 older (greater than 60 years) men and women. After an extensive baseline physiologic assessment (Time 1), in which aerobic capacity and blood lipids were measured, sub ... Full text Link to item Cite

Stress reactivity and exercise training in premenopausal and postmenopausal women.

Journal article Health Psychol · 1991 Featured Publication Examined the influence of ovarian function on psychophysiological stress responses and determined if aerobic exercise reduced stress reactivity. Fifty premenopausal and postmenopausal women initially were subjected to a public speaking task and an ice-on-t ... Full text Link to item Cite

A preliminary study of the effects of cardiac procedures on cognitive performance.

Journal article Int J Psychosom · 1991 Featured Publication The effects of three commonly performed cardiac procedures on cognitive performance were evaluated in patients undergoing coronary artery bypass graft (CABG) surgery (N = 20), percutaneous transluminal coronary angioplasty (PTCA) procedure (N = 8), or card ... Link to item Cite

Effects of exercise training on cardiovascular function and plasma lipid, lipoprotein, and apolipoprotein concentrations in premenopausal and postmenopausal women.

Journal article Arterioscler Thromb · 1991 Featured Publication This study examined the effects of aerobic exercise on lipid levels in premenopausal and postmenopausal women. Fifty healthy middle-aged women (mean age, 50 years) were randomly assigned to 12 weeks of either aerobic exercise (walking and jogging) or nonae ... Full text Link to item Cite

Temporal stability of the hemodynamics of cardiovascular reactivity.

Journal article Int J Psychophysiol · November 1990 Featured Publication Cardiovascular responses to a competitive reaction-time task were monitored in 13 male subjects tested twice, 3 months apart. The temporal stability of blood pressure responses was in line with previous reports. However, in this study impedance cardiograph ... Full text Link to item Cite

Quality of life among hypertensive patients with a diuretic background who are taking atenolol and enalapril.

Journal article Clin Pharmacol Ther · October 1990 Featured Publication The cardioselective beta-blocker atenolol and the angiotensin-converting enzyme inhibitor enalapril were compared for efficacy, safety, and quality-of-life factors in 30 patients with hypertension whose hypertension was inadequately controlled with diureti ... Full text Link to item Cite

Physiological, psychological, and behavioral factors and white coat hypertension.

Journal article Hypertension · August 1990 Featured Publication Patients with hypertension in the clinic but not during daily activities ("white coat" hypertension) may be at lower risk of hypertensive morbidity and mortality than patients with hypertension in both settings ("persistent" hypertension). We hypothesized ... Full text Link to item Cite

Perceived change among participants in an exercise program for older adults.

Journal article Gerontologist · August 1990 Featured Publication Data regarding perceived change were collected as part of a study of the effects of aerobic exercise training on psychological, cognitive, and physiological functioning among 101 healthy older adults. Subjects were assigned randomly to an aerobic exercise ... Full text Link to item Cite

Aerobic exercise reduces levels of cardiovascular and sympathoadrenal responses to mental stress in subjects without prior evidence of myocardial ischemia.

Journal article Am J Cardiol · January 1, 1990 Featured Publication Thirty-seven healthy type A men (mean age 42 years) were randomly assigned to either an aerobic exercise training group or to a strength and flexibility training group. Before exercise, subjects underwent comprehensive physiologic and behavioral assessment ... Full text Link to item Cite

Cardiovascular responses during upright and semi-recumbent cycle ergometry testing.

Journal article Med Sci Sports Exerc · October 1989 Featured Publication To compare cardiovascular (CV) responses during cycle ergometry testing, 20 unmedicated mild hypertensive subjects (10 male, 10 female; mean age = 47.9 yr) underwent exercise testing on an upright (UP) cycle and a semi-recumbent (SR) cycle. Tests were admi ... Link to item Cite

Type A behavior and survival: a follow-up study of 1,467 patients with coronary artery disease.

Journal article Am J Cardiol · September 1, 1989 Featured Publication Patients with documented coronary artery disease, admitted to Duke Medical Center between 1974 and 1980, were assessed for type A behavior pattern and were followed until 1984. The relation of type A behavior to survival was tested using data from coronary ... Full text Link to item Cite

Improving aerobic capacity in healthy older adults does not necessarily lead to improved cognitive performance.

Journal article Psychol Aging · September 1989 Featured Publication The effects of aerobic exercise training in a sample of 85 older adults were investigated. Ss were assigned randomly to either an aerobic exercise group, a nonaerobic exercise (yoga) group, or a waiting-list control group. Following 16 weeks of the group-s ... Full text Link to item Cite

Cardiovascular and behavioral effects of aerobic exercise training in healthy older men and women.

Journal article J Gerontol · September 1989 Featured Publication The cardiovascular and behavioral adaptations associated with a 4-month program of aerobic exercise training were examined in 101 older men and women (mean age = 67 years). Subjects were randomly assigned to an Aerobic Exercise group, a Yoga and Flexibilit ... Full text Link to item Cite

Effects of aerobic exercise training on hemodynamic responses during psychosocial stress in normotensive and borderline hypertensive type A men: a preliminary report.

Journal article Psychosom Med · 1989 Featured Publication This study assessed the effects of aerobic exercise training on cardiovascular responses to a 5-min reaction time competition task. Twenty-seven Type A men (aged 30-56) participated in this randomized study in which 14 underwent supervised aerobic training ... Full text Link to item Cite

Cardiovascular responses in the laboratory and in the natural environment: is blood pressure reactivity to laboratory-induced mental stress related to ambulatory blood pressure during everyday life?

Journal article J Psychosom Res · 1989 Featured Publication Cardiovascular activity recorded at rest and during mental stress in the laboratory was studied in relation to ambulatory recorded cardiovascular activity at work and at home. Fifty-five Type A men (M = 42.4 years) underwent a standardized laboratory menta ... Full text Link to item Cite

Slowing of memory-search performance in men with mild hypertension.

Journal article Health Psychol · 1989 Featured Publication Previous reports have associated hypertension with a slowing of cognitive performance, although the component processes involved have not been identified. Our report compares the performance of 24 men with mild hypertension and 28 age-matched normotensive ... Full text Link to item Cite

Effects of aerobic exercise training, age, and physical fitness on memory-search performance.

Journal article Psychol Aging · September 1988 Featured Publication We investigated the effects of exercise training on memory performance. One group of 13 men (M = 42.92 years of age) participated in supervised aerobic exercise (jogging) three times a week for 12 weeks. A second group of 15 men (M = 43.67 years of age) pe ... Full text Link to item Cite

Rehabilitation of patients following myocardial infarction.

Journal article J Consult Clin Psychol · June 1988 Featured Publication Full text Link to item Cite

Effects of beta-blockade and exercise on cardiovascular and cognitive functioning.

Journal article Hypertension · May 1988 Featured Publication Twenty-four men with mild essential hypertension were assigned randomly to receive propranolol (n = 9), atenolol (n = 7), or a placebo (n = 8). All subjects participated in a 12-week study and provided physiological and behavioral data four times during th ... Full text Link to item Cite

Short-term behavioral effects of beta-adrenergic medications in men with mild hypertension.

Journal article Clin Pharmacol Ther · April 1988 Featured Publication beta-Adrenergic-inhibiting drugs are widely prescribed for the treatment of hypertension. These drugs have previously been found to influence a variety of psychologic and behavioral functions and have, in some cases, been associated with serious psychiatri ... Full text Link to item Cite

Type A behavior and angiographically documented coronary atherosclerosis in a sample of 2,289 patients.

Journal article Psychosom Med · 1988 Featured Publication To determine the relationship between Type A behavior pattern and angiographically documented coronary atherosclerosis (CAD), we analyzed risk factor, behavioral, and angiographic data collected on 2,289 patients undergoing diagnostic coronary angiography ... Full text Link to item Cite

Comparison of high- and low-intensity exercise training early after acute myocardial infarction.

Journal article Am J Cardiol · January 1, 1988 Featured Publication The effects of the intensity of exercise training on cardiorespiratory variables were investigated in a consecutive series of men with recent (median 8 weeks) acute myocardial infarction. Forty-five patients were randomly assigned either to a high- (65 to ... Full text Link to item Cite

Exercise training in healthy type A middle-aged men: effects on behavioral and cardiovascular responses.

Journal article Psychosom Med · 1988 Featured Publication Thirty-six healthy Type A men (means = 44.4 years) were randomly assigned to either an aerobic exercise training group or a strength and flexibility training group. Subjects completed a comprehensive psychological assessment battery before and after the ex ... Full text Link to item Cite

Psychological correlates of hostility among patients undergoing coronary angiography.

Journal article Br J Med Psychol · December 1987 Featured Publication The Cook-Medley Hostility (Ho) scale (Cook & Medley, 1954) has been associated with increased risk for coronary heart disease (CHD). There is relatively little information about the psychosocial correlates of the Ho scale in clinical or adult populations, ... Full text Link to item Cite

Behavioral approaches to secondary prevention of coronary heart disease.

Journal article Circulation · July 1987 Featured Publication Over the past 10 years behavioral approaches to the treatment of coronary heart disease (CHD) have become widely recognized as being a significant complement to traditional medical and surgical therapies. The success of approaches to secondary prevention n ... Link to item Cite

Nonpharmacologic approaches to the treatment of hypertension.

Journal article Circulation · July 1987 Featured Publication Link to item Cite

Psychological risk factors in coronary artery disease.

Journal article Circulation · July 1987 Featured Publication Link to item Cite

Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert.

Journal article J Virol · April 1987 Featured Publication Hardy-Zuckerman 2 feline sarcoma virus (HZ2-FeSV), isolated from a multicentric feline fibrosarcoma is a replication-defective acute transforming feline retrovirus which originated by transduction of feline c-abl sequences with feline leukemia virus (FeLV) ... Full text Link to item Cite

Social support, type A behavior, and coronary artery disease.

Journal article Psychosom Med · 1987 Featured Publication The interaction of Type A behavior and social support in relation to the degree of coronary artery disease (CAD) severity was investigated. One hundred thirteen patients undergoing diagnostic coronary angiography received the Type A structured interview (S ... Full text Link to item Cite

Angina pectoris in type A and type B cardiac patients.

Journal article Pain · November 1986 Featured Publication The type A behavior pattern is characterized by excessive competitive drive, a sense of time urgency, enhanced aggressiveness, hostility and a persistent desire for recognition. Type A behaviour is widely recognized as a risk factor in coronary heart disea ... Full text Link to item Cite

Type As who think they are type Bs: discrepancies between self-ratings and interview ratings of the type A (coronary-prone) behaviour pattern.

Journal article Br J Med Psychol · March 1986 Featured Publication The study described here explored discrepancies between self-ratings and interview ratings of Type A behaviour. A total of 281 patients referred for diagnostic coronary angiography underwent a comprehensive psychological assessment including the Type A str ... Full text Link to item Cite

Psychosocial and physical predictors of anginal pain relief with medical management.

Journal article Psychosom Med · 1986 Featured Publication This study was undertaken to identify psychosocial and physical characteristics that independently predict anginal pain relief. The original study group comprised over 570 patients in whom the characteristics were identified at the time of coronary arterio ... Full text Link to item Cite

Memory performance by mild hypertensives following beta-adrenergic blockade.

Journal article Psychopharmacology (Berl) · 1986 Featured Publication Previous experiments have reported deficits in cognitive performance following the administration of beta-adrenoceptor antagonists. These deficits have not appeared consistently, however, and it is not clear from previous studies whether changes in the cen ... Full text Link to item Cite

Relationships among age, sex, the type A behavior pattern, and cardiovascular reactivity.

Journal article J Gerontol · November 1985 Featured Publication Most investigations of Type A behavior and cardiovascular responsivity have used age-homogeneous, male samples. In this study, heart rate (HR) and blood pressure responses were obtained from men and women, age 27 to 70, during mental arithmetic and a visua ... Full text Link to item Cite

Age differences in self-perceptions of type A traits.

Journal article J Consult Clin Psychol · April 1985 Featured Publication Full text Link to item Cite

Components of Type A, hostility, and anger-in: relationship to angiographic findings.

Journal article Psychosom Med · 1985 Featured Publication Previous research has linked the Type A coronary-prone behavior pattern to angiographically documented severity of coronary atherosclerosis (CAD). The present study sought through component scoring of the Type A Structured Interview (SI) to determine what ... Full text Link to item Cite

Development of a brief self-report measure of the type A (coronary prone) behavior pattern.

Journal article J Psychosom Res · 1985 Featured Publication This study reports the development of a brief self-report measure of the Type A behavior pattern based upon a set of adjectives derived from the Gough Adjective Checklist (ACL). Previous work from our laboratory established a set of adjectives identified b ... Full text Link to item Cite

The inhibited power motive, type A behavior, and patterns of cardiovascular response during the structured interview and Thematic Apperception Test.

Journal article J Human Stress · 1985 Featured Publication The Type A behavior pattern and the inhibited power motive have been implicated in the development of coronary heart disease (CHD). Since it is widely believed that enhanced cardiovascular responsivity may be one mechanism by which individuals develop CHD, ... Full text Link to item Cite

Is running an analogue of anorexia nervosa? An empirical study of obligatory running and anorexia nervosa.

Journal article JAMA · July 27, 1984 Featured Publication A recent report suggested that compulsive runners share a common set of psychological traits and behavioral dispositions with patients with anorexia nervosa. In an effort to objectively assess the similarity between anorexia nervosa and obligatory running, ... Link to item Cite

Feasibility and benefits of exercise training in patients on maintenance dialysis.

Journal article Kidney Int · June 1984 Featured Publication Fourteen of 174 patients receiving maintenance dialysis volunteered to participate in a 12-week exercise conditioning program. Seven patients attended more than 50% (range, 55 to 75%) of the sessions held three times each week. These seven patients achieve ... Full text Link to item Cite

Behavioral assessment of the type A behavior pattern.

Journal article Psychosom Med · 1984 Featured Publication The present study attempted to assess systematically a set of behavioral subcomponents associated with the Type A behavior pattern. Sixty middle-aged men underwent the structured interview (SI) and a repeated version of the SI after a four-month interval. ... Full text Link to item Cite

Physical conditioning and left ventricular performance in the elderly: assessment by radionuclide angiocardiography.

Journal article Am J Cardiol · August 1983 Featured Publication In contrast to young persons, normal elderly persons who undergo symptom-limited dynamic exercise demonstrate a decrease in left ventricular (LV) contractile performance characterized by a decrease in LV ejection fraction. To test the hypothesis that physi ... Full text Link to item Cite

Psychological changes accompany aerobic exercise in healthy middle-aged adults.

Journal article Psychosom Med · December 1982 Featured Publication An attempt was made to assess the effects of aerobic exercise on the psychological functioning of a nonclinical sample of healthy middle-aged adults. Sixteen subjects participated in a 10-week program of regular walking-jogging, while a matched control gro ... Full text Link to item Cite

Physiological and psychological variables predict compliance to prescribed exercise therapy in patients recovering from myocardial infarction.

Journal article Psychosom Med · December 1982 Featured Publication Previous research has documented high rates of noncompliance to prescribed medical therapy in patients recovering from myocardial infarction (MI). This study was undertaken to determine if patients who subsequently drop out of a structured cardiac rehabili ... Full text Link to item Cite

Psychological and physiological effects of physical conditioning on the elderly.

Journal article J Psychosom Res · 1982 Featured Publication A decline in cardiovascular functioning is generally thought to occur with advancing age. The purpose of the present study was to assess the effects of regular aerobic exercise on a group of 24 young-old (65-69) and old-old (70-85 yr) volunteers. Comprehen ... Full text Link to item Cite

Self-ratings of type A (coronary prone) adults: do type A's know they are type A's?

Journal article Psychosom Med · October 1981 Featured Publication This study compared self-ratings and interview-band ratings of the type A coronary-prone behavior pattern. A Type A adjective scale was developed from the Gough-Adjective Checklist (ACL), using adjectives rated as characteristic and uncharacteristic of the ... Full text Link to item Cite

Assessment of conceptual tempo in the type A (coronary prone) behavior pattern.

Journal article J Pers Assess · February 1981 Featured Publication Previous research has documented an association between a particular behavioral complex termed Type A, and increased incidence of coronary heart disease. In an effort to define further some of the behavioral characteristics that distinguish Type A subjects ... Full text Link to item Cite

Type A behavior, hostility, and coronary atherosclerosis.

Journal article Psychosom Med · November 1980 Featured Publication Type A behavior pattern was assessed using the structured interview and hostility level was assessed using a subscale of the Minnesota Multiphase Personality Inventory in 424 patients who underwent diagnostic coronary arteriography for suspected coronary h ... Full text Link to item Cite

Effects of exercise on the Type A (coronary prone) behavior pattern.

Journal article Psychosom Med · March 1980 Featured Publication This study presents the initial findings of an attempt to reduce the risk of coronary heart disease (CHD) in a group of health, middle-aged adults by participation in a ten-week, supervised exercise program. Forty-six subjects were classified as Type A or ... Full text Link to item Cite

Anxiety-proneness and coronary heart disease.

Journal article J Psychosom Res · 1979 Featured Publication Full text Link to item Cite

Type A behavior pattern and coronary atherosclerosis.

Journal article Circulation · October 1978 Featured Publication Previous research has demonstrated an increased rate of clinical coronary heart disease (CHD) events among people who exhibit a "coronary prone" (Type A) behavior pattern. This study was undertaken to determine whether the association between behavior patt ... Full text Link to item Cite

Treatment of thrombosed hemorrhoids by excision.

Journal article Am J Surg · October 1970 Featured Publication Full text Link to item Cite