Scholars@Duke
James Alan Blumenthal

James Alan Blumenthal

J. P. Gibbons Distinguished Professor Emeritus of Psychiatry
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
james.blumenthal@duke.edu
Box 3119 Med Ctr, Durham, NC 27710
4567 Hosp South, Durham, NC 27710

Scholarly Works - Journal articles

Lifestyle, sleep quality, and cognitive function in resistant hypertension: One-year follow-up from the TRIUMPH trial.

Journal article J Alzheimers Dis · February 2026 BackgroundTreatment resistant hypertension (TRH) is associated with increased risk of cognitive decline, which may be reduced by healthy lifestyle changes.ObjectiveTo examine the effects of a comprehensive, rehabilitation-based lifestyle hprogram on cognit ... Full text Link to item Cite

Telehealth interventions to improve outcomes in lung transplant recipients: Primary results of the INSPIRE-III randomized clinical trial.

Journal article J Heart Lung Transplant · September 2025 BACKGROUND: There is growing evidence that many patients undergoing lung transplantation report significant distress and low physical activity (PA), which might not improve despite lung transplantation and may be associated with worse clinical outcomes. Fe ... Full text Link to item Cite

Neurocognitive Dysfunction After Short (<20 Minutes) Duration Hypothermic Circulatory Arrest.

Journal article Ann Thorac Surg · February 2025 BACKGROUND: It has long been held that the safe duration of hypothermic circulatory arrest (HCA) is at least 25 to 30 minutes. However, this belief is based primarily on clinical outcomes research and has not been systematically investigated using more sen ... Full text Link to item Cite

Depressive symptoms are associated with clinical outcomes in heart failure with reduced ejection fraction.

Journal article ESC Heart Fail · October 2024 AIMS: The objective of this study was to examine associations between elevated depressive symptoms and increased risk of adverse clinical events patients with heart failure and reduced ejection fraction (HFrEF), as well as the potential contribution of hea ... Full text Link to item Cite

Cognitive behavior therapy for insomnia for untreated hypertension with comorbid insomnia disorder: The SLEEPRIGHT clinical trial.

Journal article J Clin Hypertens (Greenwich) · April 2024 Insomnia and poor sleep are associated with an increased risk of developing cardiovascular disease (CVD) and its precursors, including hypertension. In 2022, the American Heart Association (AHA) added inadequate sleep to its list of health behaviors that i ... Full text Link to item Cite

Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest Trial (GOT ICE): A Randomized Clinical Trial Comparing Outcomes After Aortic Arch Surgery.

Journal article Circulation · February 27, 2024 BACKGROUND: Deep hypothermia has been the standard for hypothermic circulatory arrest (HCA) during aortic arch surgery. However, centers worldwide have shifted toward lesser hypothermia with antegrade cerebral perfusion. This has been supported by retrospe ... Full text Link to item Cite

Effects of Lifestyle Modification on Psychosocial Function in Patients With Resistant Hypertension: SECONDARY OUTCOMES FROM THE TRIUMPH RANDOMIZED CLINICAL TRIAL.

Journal article J Cardiopulm Rehabil Prev · January 1, 2024 PURPOSE: In a secondary analysis of the TRIUMPH clinical trial, psychological outcomes in patients with resistant hypertension (RH) receiving a diet and exercise intervention delivered in a cardiac rehabilitation setting were compared with those receiving ... Full text Link to item Cite

Is exercise a viable therapy for anxiety? Systematic review of recent literature and critical analysis.

Journal article Prog Cardiovasc Dis · 2024 OBJECTIVES: Exercise has been promoted as a treatment for a variety of psychiatric conditions. The benefits of exercise for depression are widely recognized, but the benefits of exercise for anxiety are uncertain. Although several reviews promoted exercise ... Full text Link to item Cite

Lifestyle Medicine as a Treatment for Resistant Hypertension.

Journal article Curr Hypertens Rep · October 2023 PURPOSE OF REVIEW: Approximately 10% of the adults with hypertension fail to achieve the recommended blood pressure treatment targets on 3 antihypertensive medications or require ≥ 4 medications to achieve goal. These patients with 'resistant hypertension ... Full text Link to item Cite

Infant Outcomes in Hypertensive Women: Are there Moderating Effects of Prenatal Care and Race/Ethnicity?

Journal article Matern Child Health J · July 2023 BACKGROUND: Hypertensive disorders of pregnancy is one of the leading causes of adverse infant outcomes. Black women are disproportionately affected by hypertensive disorders of pregnancy, and it associated adverse outcomes. Adequate prenatal care may impr ... Full text Link to item Cite

Clinical guidelines for the use of lifestyle-based mental health care in major depressive disorder: World Federation of Societies for Biological Psychiatry (WFSBP) and Australasian Society of Lifestyle Medicine (ASLM) taskforce.

Journal article World J Biol Psychiatry · June 2023 OBJECTIVES: The primary objectives of these international guidelines were to provide a global audience of clinicians with (a) a series of evidence-based recommendations for the provision of lifestyle-based mental health care in clinical practice for adults ... Full text Link to item Cite

Inflammation moderates the effects of lifestyle modification on neurocognition among individuals with resistant hypertension.

Journal article J Clin Hypertens (Greenwich) · January 2023 Individuals with resistant hypertension (RH) have the greatest risk of cerebrovascular disease and cognitive impairment among individuals with hypertension. Elevated levels of pro-inflammatory cytokines may represent a critical yet unexamined factor influe ... Full text Link to item Cite

Exercise as a therapeutic modality for the prevention and treatment of depression.

Journal article Prog Cardiovasc Dis · 2023 While maintaining an active lifestyle and engaging in regular exercise are known to promote cardiovascular (CV) health, increasing evidence has emerged to indicate that these lifestyle behaviors also can promote psychological health and well-being. This ha ... Full text Link to item Cite

Cardiology and lifestyle medicine.

Journal article Prog Cardiovasc Dis · 2023 Poor lifestyle habits, such as physical inactivity and poor diets, are highly prevalent within society and even more so among patients with chronic disease. The need to stem poor lifestyle habits has led to the development of a new field of Lifestyle Medic ... Full text Link to item Cite

Sleep Quality, Metabolic Function, Physical Activity, and Neurocognition Among Individuals with Resistant Hypertension.

Journal article J Alzheimers Dis · 2023 BACKGROUND: Resistant hypertension (RH) is a major risk factor for stroke, cognitive decline, and dementia. Sleep quality is increasingly suggested to play an important role linking RH to cognitive outcomes, although the mechanisms linking sleep quality to ... Full text Link to item Cite

Exercise and Escitalopram in the Treatment of Anxiety in Patients with Coronary Heart Disease: One Year Follow-Up of the UNWIND Randomized Clinical Trial.

Journal article J Cardiovasc Dev Dis · September 22, 2022 Anxiety is common among patients with coronary heart disease (CHD) and is associated with a worse prognosis. UNWIND was a 12-week randomized clinical trial comparing exercise and escitalopram to placebo on measures of anxiety, depression, and CHD biomarker ... Full text Link to item Cite

Longer term benefits of exercise and escitalopram in the treatment of anxiety in patients with coronary heart disease: Six month follow-up of the UNWIND randomized clinical trial.

Journal article Am Heart J · September 2022 BACKGROUND: Anxiety is a common comorbidity in patients with coronary heart disease (CHD) and is associated with worse prognosis. However, effective treatment for anxiety in CHD patients is uncertain. The UNWIND randomized clinical trial showed that 12-wee ... Full text Link to item Cite

Lifestyle modification and cognitive function among individuals with resistant hypertension: cognitive outcomes from the TRIUMPH trial.

Journal article J Hypertens · July 1, 2022 BACKGROUND: Resistant hypertension is associated with increased risk of cognitive decline, stroke, and dementia. Lifestyle modification has been suggested to improve cognitive function through its salutary effects on vascular function. METHODS: Participant ... Full text Link to item Cite

Hypertension and infant outcomes: North Carolina pregnancy risks assessment monitoring system data.

Journal article Pregnancy Hypertens · June 2022 This study examined the risk factors that moderate the relationship between hypertension and infant outcomes or were independent risk factors in a large and diverse sample of pregnant women with and without hypertension before conception. The sample includ ... Full text Link to item Cite

Trajectories of depressive symptoms and subsequent cognitive decline in older adults: a pooled analysis of two longitudinal cohorts.

Journal article Age Ageing · January 6, 2022 BACKGROUND: the course of depression is variable, but it is unknown how this variability over time affects long-term cognitive decline. OBJECTIVE: to examine the relationship of different trajectories of depressive symptoms on rates of subsequent cognitive ... Full text Link to item Cite

Effects of a Weight and Pain Management Program in Patients With Rheumatoid Arthritis With Obesity: A Randomized Controlled Pilot Investigation.

Journal article J Clin Rheumatol · January 1, 2022 BACKGROUND: Obesity is associated with poor outcomes for patients with rheumatoid arthritis (RA). Effective weight management is imperative. Although traditional lifestyle behavioral weight loss programs have demonstrated efficacy for reducing weight, thes ... Full text Link to item Cite

Cerebrovascular Function, Vascular Risk, and Lifestyle Patterns in Resistant Hypertension.

Journal article J Alzheimers Dis · 2022 BACKGROUND: Impaired cerebrovascular reactivity (CVR) and blunted cerebral hemodynamic recruitment are thought to be important mechanisms linking hypertension to cerebrovascular and cognitive outcomes. Few studies have examined cardiovascular or dietary co ... Full text Link to item Cite

Effect of Exercise, Escitalopram, or Placebo on Anxiety in Patients With Coronary Heart Disease: The Understanding the Benefits of Exercise and Escitalopram in Anxious Patients With Coronary Heart Disease (UNWIND) Randomized Clinical Trial.

Journal article JAMA Psychiatry · November 1, 2021 IMPORTANCE: Anxiety is common among patients with coronary heart disease (CHD) and is associated with worse health outcomes; however, effective treatment for anxiety in patients with CHD is uncertain. OBJECTIVE: To determine whether exercise and escitalopr ... Full text Link to item Cite

Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial.

Journal article Circulation · October 12, 2021 BACKGROUND: Although lifestyle modifications generally are effective in lowering blood pressure (BP) among patients with unmedicated hypertension and in those treated with 1 or 2 antihypertensive agents, the value of exercise and diet for lowering BP in pa ... Full text Link to item Cite

Exercise Prescription Practices to Improve Mental Health.

Journal article J Psychiatr Pract · July 28, 2021 OBJECTIVE: There is growing evidence that higher levels of physical activity are associated with better mental health. Furthermore, interventional studies have shown that exercise may improve symptoms in a number of psychiatric conditions. Despite this evi ... Full text Link to item Cite

Effects of Acute Exercise on Anxiety Ratings in Patients With Coronary Heart Disease and Elevated Anxiety.

Journal article J Cardiopulm Rehabil Prev · July 1, 2021 PURPOSE: To explore individual differences in state anxiety following a single, acute bout of aerobic exercise among anxious patients with diagnosed coronary heart disease (CHD). METHODS: One hundred eighteen CHD patients with elevated symptoms of anxiety ... Full text Link to item Cite

C4 article: Implications of COVID-19 in transplantation.

Journal article Am J Transplant · May 2021 A novel coronavirus has had global impact on individual health and health care delivery. In this C4 article, contributors discuss various aspects of transplantation including donor and recipient screening, management of infected patients, and prevention of ... Full text Open Access Link to item Cite

Risk stratification after acute myocardial infarction by amplitude-frequency mapping of cyclic variation of heart rate.

Journal article Ann Noninvasive Electrocardiol · May 2021 BACKGROUND: Blunted cyclic variation of heart rate (CVHR), measured as a decrease in CVHR amplitude (Acv), predicts mortality risk after acute myocardial infarction (AMI). However, Acv also can be reduced in mild sleep apnea with mild O2 desaturation. We i ... Full text Link to item Cite

Actigraphy-Derived Sleep Efficiency Is Associated With Endothelial Function in Men and Women With Untreated Hypertension.

Journal article Am J Hypertens · March 11, 2021 BACKGROUND: Poor sleep quality is increasingly recognized as an important and potentially modifiable risk factor for cardiovascular disease (CVD). Impaired endothelial function may be 1 mechanism underlying the association between poor sleep and CVD risk. ... Full text Link to item Cite

The role of comorbid anxiety in exercise and depression trials: Secondary analysis of the SMILE-II randomized clinical trial.

Journal article Depress Anxiety · February 2021 OBJECTIVES: To explore the anxiolytic effects of a 4-month randomized, placebo-controlled trial of exercise and antidepressant medication in patients with major depressive disorder (MDD), and to examine the potential modifying effects of anxiety in treatin ... Full text Link to item Cite

Survival Predictors of Heart Rate Variability After Myocardial Infarction With and Without Low Left Ventricular Ejection Fraction.

Journal article Front Neurosci · 2021 BACKGROUND: Heart rate variability (HRV) and heart rate (HR) dynamics are used to predict the survival probability of patients after acute myocardial infarction (AMI), but the association has been established in patients with mixed levels of left ventricul ... Full text Link to item Cite

Depression, Immunosuppressant Levels, and Clinical Outcomes in Postlung Transplant Recipients.

Journal article Int J Psychiatry Med · November 2020 OBJECTIVE: Posttransplant depression has been linked to increased risk for adverse outcomes in lung transplant patients. Maintaining target serum immunosuppressant levels is also essential for optimal lung transplant clinical outcome and may be a crucial p ... Full text Link to item Cite

High-Mobility Group Box-1 Is Associated With Obesity, Inflammation, and Subclinical Cardiovascular Risk Among Young Adults: A Longitudinal Cohort Study.

Journal article Arterioscler Thromb Vasc Biol · November 2020 OBJECTIVE: We aimed to characterize circulating HMGB1 (high-mobility group box-1) levels, one of the better-characterized damage-associated molecular patterns, with respect to age, sex, and race in the general population, and investigate the longitudinal a ... Full text Link to item Cite

Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100 667 Patients.

Journal article Circulation · August 18, 2020 BACKGROUND: To quantify the association between effects of interventions on carotid intima-media thickness (cIMT) progression and their effects on cardiovascular disease (CVD) risk. METHODS: We systematically collated data from randomized, controlled trial ... Full text Link to item Cite

Vascular α1-Adrenergic Receptor Responsiveness in Masked Hypertension.

Journal article Am J Hypertens · August 4, 2020 BACKGROUND: Masked hypertension (nonhypertensive in the clinic setting but hypertensive outside the clinic during wakefulness) is characterized by increased blood pressure in response to physical and emotional stressors that activate the sympathetic nervou ... Full text Link to item Cite

Longer Term Effects of Diet and Exercise on Neurocognition: 1-Year Follow-up of the ENLIGHTEN Trial.

Journal article J Am Geriatr Soc · March 2020 OBJECTIVES: To evaluate the longer term changes in executive functioning among participants with cardiovascular disease (CVD) risk factors and cognitive impairments with no dementia (CIND) randomized to a diet and exercise intervention. DESIGN: A 2 (Exerci ... Full text Link to item Cite

Remote Therapy to Improve Outcomes in Lung Transplant Recipients: Design of the INSPIRE-III Randomized Clinical Trial.

Journal article Transplant Direct · March 2020 BACKGROUND: Impaired functional capacity and emotional distress are associated with lower quality of life (QoL) and worse clinical outcomes in post lung transplant patients. Strategies to increase physical activity and reduce distress are needed. METHODS: ... Full text Link to item Cite

Metabolic and Neurocognitive Changes Following Lifestyle Modification: Examination of Biomarkers from the ENLIGHTEN Randomized Clinical Trial.

Journal article J Alzheimers Dis · 2020 BACKGROUND: Previous studies have demonstrated that aerobic exercise (AE) and the Dietary Approaches to Stop Hypertension (DASH) diet can improve neurocognition. However, the mechanisms by which lifestyle improves neurocognition have not been widely studie ... Full text Link to item Cite

Association of Depression and Unhealthy Lifestyle Behaviors in Chinese Patients With Acute Coronary Syndromes.

Journal article J Cardiopulm Rehabil Prev · November 2019 PURPOSE: This study sought to examine associations between depression and unhealthy lifestyle behaviors in Chinese patients with acute coronary syndromes (ACS). METHODS: This cross-sectional study included 4043 ACS patients from 16 hospitals across China w ... Full text Link to item Cite

Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial.

Journal article Anesthesiology · June 2019 BACKGROUND: Cognitive decline after cardiac surgery occurs frequently and persists in a significant proportion of patients. Preclinical studies and human trials suggest that intravenous lidocaine may confer protection in the setting of neurologic injury. I ... Full text Open Access Link to item Cite

The modifying effects of social support on psychological outcomes in patients with heart failure.

Journal article Health Psychol · June 2019 OBJECTIVE: We examined the modifying effects of social support on depressive symptoms and health-related quality of life (QoL) in patients receiving coping skills training (CST). METHOD: We considered the modifying effects of social support in the Coping E ... Full text Link to item Cite

Neurocognition in treatment-resistant hypertension: profile and associations with cardiovascular biomarkers.

Journal article J Hypertens · May 2019 BACKGROUND: Hypertension in midlife has been associated with increased risk of stroke and neurocognitive decline. Few studies, however, have examined neurocognition among individuals with treatment-resistant hypertension or potential mechanisms by which tr ... Full text Link to item Cite

Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial.

Journal article Neurology · January 15, 2019 OBJECTIVE: To determine the independent and additive effects of aerobic exercise (AE) and the Dietary Approaches to Stop Hypertension (DASH) diet on executive functioning in adults with cognitive impairments with no dementia (CIND) and risk factors for car ... Full text Link to item Cite

The Effects of Ambulatory Blood Pressure Monitoring on Sleep Quality in Men and Women With Hypertension: Dipper vs. Nondipper and Race Differences.

Journal article Am J Hypertens · January 1, 2019 BACKGROUND: The nondipping circadian blood pressure (BP) profile is associated with both poor sleep quality and increased cardiovascular risk. The present study aimed to clarify the potential confounding effects of 24-hour ambulatory blood pressure monitor ... Full text Link to item Cite

Comparison of treatment options for depression in heart failure: A network meta-analysis.

Journal article J Psychiatr Res · January 2019 BACKGROUND: Depression independently predicts poor outcomes in heart failure (HF) patients, including increased mortality, morbidity and 30-day re-hospitalization. In this network meta-analysis, we compared different interventions designed to treat depress ... Full text Link to item Cite

Health, Physical Growth, and Neurodevelopmental Outcomes in Preterm Infants of Women With Hypertensive Disorders of Pregnancy.

Journal article J Obstet Gynecol Neonatal Nurs · January 2019 OBJECTIVE: To compare the health, physical growth, and developmental outcomes in preterm infants of women with and without hypertensive disorders of pregnancy (HDP). DESIGN: Cross-sectional analysis of health outcomes; physical growth (head circumference, ... Full text Link to item Cite

Association Between Insulin Resistance, Plasma Leptin, and Neurocognition in Vascular Cognitive Impairment.

Journal article J Alzheimers Dis · 2019 BACKGROUND: Greater body weight has been associated impairments in neurocognition and greater dementia risk, although the mechanisms linking weight and neurocognition have yet to be adequately delineated. OBJECTIVE: To examine metabolic mechanisms underlyi ... Full text Link to item Cite

Microvascular Endothelial Function and Neurocognition Among Adults With Major Depressive Disorder.

Journal article Am J Geriatr Psychiatry · October 2018 BACKGROUND: Cardiovascular risk factors (CVRFs) and endothelial dysfunction have been associated independently with poorer neurocognition in middle-aged adults, particularly on tests of frontal lobe function. However, to our knowledge, no studies have exam ... Full text Link to item Cite

I-CARE randomized clinical trial integrating depression and acute coronary syndrome care in low-resource hospitals in China: Design and rationale.

Journal article Am Heart J · August 2018 Depression and acute coronary syndromes (ACS) are both common public health challenges. Patients with ACS often develop depression, which in turn adversely affects prognosis. Low-cost, sustainable, and effective service models that integrate depression car ... Full text Link to item Cite

Sedentary Behavior and the Risk of Depression in Patients With Acute Coronary Syndromes.

Journal article Am J Cardiol · June 15, 2018 Although there is good evidence that sedentary behavior is associated with poor health outcomes in healthy persons and patients with cardiovascular disease, the mental health consequences of sedentary behavior have not been widely studied. In this report, ... Full text Link to item Cite

Depression, social support, and clinical outcomes following lung transplantation: a single-center cohort study.

Journal article Transpl Int · May 2018 Depressive symptoms are common among lung transplant candidates and have been associated with poorer clinical outcomes in some studies. Previous studies have been plagued by methodologic problems, including small sample sizes, few clinical events, and unco ... Full text Link to item Cite

Neurological Sequelae and Clinical Outcomes After Lung Transplantation.

Journal article Transplant Direct · April 2018 BACKGROUND: Neurological complications are common after lung transplantation. However, no large cohort studies have examined the incidence, predictors, and clinical significance of neurological events sustained by lung transplant recipients. METHODS: We co ... Full text Open Access Link to item Cite

Postoperative cognitive dysfunction and mortality following lung transplantation.

Journal article Am J Transplant · March 2018 Preliminary evidence suggests that postoperative cognitive dysfunction (POCD) is common after lung transplantation. The impact of POCD on clinical outcomes has yet to be studied. The association between POCD and longer-term survival was therefore examined ... Full text Link to item Cite

Circadian hemodynamics in men and women with high blood pressure: dipper vs. nondipper and racial differences.

Journal article J Hypertens · February 2018 OBJECTIVE: The 'nondipping' pattern of circadian blood pressure (BP) variation is an established independent predictor of adverse cardiovascular outcomes. Although this phenomenon has been widely studied, its underlying circadian hemodynamics of cardiac ou ... Full text Link to item Cite

Patterns and predictors of pain following lung transplantation.

Journal article Gen Hosp Psychiatry · 2018 OBJECTIVE: Our objective was to examine variability in pain levels following lung transplantation, and examine individual biopsychosocial factors influencing changes in pain. METHOD: We performed a retrospective study of a cohort of 150 patients transplant ... Full text Link to item Cite

Impact of Racial Discrimination and Hostility on Adrenergic Receptor Responsiveness in African American Adults.

Journal article Psychosom Med · 2018 OBJECTIVE: Racial discrimination is increasingly recognized as a contributor to increased cardiovascular disease (CVD) risk among African Americans. Previous research has shown significant overlap between racial discrimination and hostility, an established ... Full text Link to item Cite

Treatment of Anxiety in Patients With Coronary Heart Disease: A Systematic Review.

Journal article Psychosomatics · 2018 BACKGROUND: Anxiety is common in patients with coronary heart disease (CHD) and is associated with an increased risk for adverse outcomes. There has been a relative paucity of studies concerning treatment of anxiety in patients with CHD. OBJECTIVE: We cond ... Full text Link to item Cite

Diagnostic Accuracy of Screening Tests and Treatment for Post-Acute Coronary Syndrome Depression: A Systematic Review.

Journal article Ann Intern Med · November 21, 2017 BACKGROUND: Patients who have had an acute coronary syndrome (ACS) event have an increased risk for depression. PURPOSE: To evaluate the diagnostic accuracy of depression screening instruments and to compare safety and effectiveness of depression treatment ... Full text Link to item Cite

Physical activity and psychosocial function following cardiac rehabilitation: One-year follow-up of the ENHANCED study.

Journal article Gen Hosp Psychiatry · November 2017 OBJECTIVE: To examine the long-term association between physical activity (PA) and psychosocial functioning following completion of cardiac rehabilitation (CR) among participants in the ENHANCED study. METHOD: ENHANCED was a 3-month clinical trial examinin ... Full text Link to item Cite

Association between normal or mildly reduced kidney function, cardiovascular risk and biomarkers for atherosclerosis: results from the ENCORE trial.

Journal article Clin Kidney J · October 2017 BACKGROUND: Moderate-to-severe kidney dysfunction is associated with atherosclerotic cardiovascular disease (ASCVD). Gradations of normal or mildly reduced kidney function may also associate with ASCVD risk. METHODS: We conducted a secondary analysis using ... Full text Link to item Cite

Blood pressure reactivity to psychological stress is associated with clinical outcomes in patients with heart failure.

Journal article Am Heart J · September 2017 INTRODUCTION: Cardiovascular (CV) reactivity to psychological stress has been implicated in the development and exacerbation of cardiovascular disease (CVD). Although high CV reactivity traditionally is thought to convey greater risk of CVD, the relationsh ... Full text Link to item Cite

Blunted cyclic variation of heart rate predicts mortality risk in post-myocardial infarction, end-stage renal disease, and chronic heart failure patients.

Journal article Europace · August 1, 2017 AIMS: Cyclic variation of heart rate (CVHR) associated with sleep-disordered breathing is thought to reflect cardiac autonomic responses to apnoeic/hypoxic stress. We examined whether blunted CVHR observed in ambulatory ECG could predict the mortality risk ... Full text Link to item Cite

Building research in diet and cognition: The BRIDGE randomized controlled trial.

Journal article Contemp Clin Trials · August 2017 Obesity has been linked to cognitive impairment, cognitive decline and dementia. Given that 38.5% of U.S. adults 60years and older are obese and these numbers are rapidly increasing, strategies to decouple obesity from cognitive decline are needed. Innovat ... Full text Link to item Cite

Racial differences in the association between heart rate variability and left ventricular mass.

Journal article Exp Physiol · July 1, 2017 What is the central question of this study? Decreased heart rate variability (HRV) is associated with increased cardiovascular disease (CVD) risk, including greater left ventricular mass (LVM). Despite their enhanced CVD risk profile, African Americans hav ... Full text Link to item Cite

Race and sex differences in cardiovascular α-adrenergic and β-adrenergic receptor responsiveness in men and women with high blood pressure.

Journal article J Hypertens · May 2017 OBJECTIVE: Hypertension is associated with unfavorable changes in adrenergic receptor responsiveness, but the relationship of race and sex to adrenergic receptor responsiveness in the development of cardiovascular disease is unclear. This study examined α- ... Full text Link to item Cite

Depressive symptoms and early mortality following lung transplantation: A pilot study.

Journal article Clin Transplant · February 2017 BACKGROUND: Impaired psychological function is common among lung transplant candidates and may affect clinical outcomes following transplantation. Although numerous studies have examined the relationship between pretransplant depression, quality of life (Q ... Full text Link to item Cite

Role of Counseling to Promote Adherence in Healthy Lifestyle Medicine: Strategies to Improve Exercise Adherence and Enhance Physical Activity.

Journal article Prog Cardiovasc Dis · 2017 Although healthy lifestyles (HL) offer a number of health benefits, nonadherence to recommended lifestyle changes remains a frequent and difficult obstacle to realizing these benefits. Behavioral counseling can improve adherence to an HL. However, individu ... Full text Link to item Cite

Effects of exercise and stress management training on nighttime blood pressure dipping in patients with coronary heart disease: A randomized, controlled trial.

Journal article Am Heart J · January 2017 INTRODUCTION: Blunted nighttime blood pressure (BP) dipping is prognostic of cardiovascular morbidity and mortality. Patients with coronary heart disease (CHD) are often characterized by a blunted nighttime BP dipping pattern. The present study compared th ... Full text Link to item Cite

Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial.

Journal article Circ Heart Fail · January 2017 BACKGROUND: Heart failure (HF) is a chronic disease that compromises patients' quality of life (QoL). Interventions designed to reduce distress and improve disease self-management are needed. We evaluated the efficacy of a telephone-based coping skills tra ... Full text Link to item Cite

Lifestyle and Neurocognition in Older Adults With Cardiovascular Risk Factors and Cognitive Impairment.

Journal article Psychosom Med · 2017 OBJECTIVE: The aim of the study was to determine the relationship of lifestyle factors and neurocognitive functioning in older adults with vascular risk factors and cognitive impairment, no dementia (CIND). METHODS: One hundred sixty adults (M [SD] = 65.4 ... Full text Link to item Cite

Influence of Kidney Function on Blood Pressure Response to Lifestyle Modifications: Secondary Analysis From the Exercise and Nutritional Interventions for Cardiovascular Health (ENCORE) Trial.

Journal article J Clin Hypertens (Greenwich) · December 2016 The kidney is an important regulator of blood pressure (BP). To determine whether BP response to lifestyle modification varies across normal ranges of kidney function, the authors examined the moderating role of estimated glomerular filtration rate (eGFR) ... Full text Link to item Cite

Hemodynamics and Vascular Hypertrophy in African Americans and Caucasians With High Blood Pressure.

Journal article Am J Hypertens · December 1, 2016 BACKGROUND: Hypertension in African Americans is characterized by greater systemic vascular resistance (SVR) compared with Caucasian Americans, but the responsible mechanisms are not known. The present study sought to determine if peripheral vascular hyper ... Full text Link to item Cite

Impact of Cardiac Rehabilitation and Exercise Training on Psychological Risk Factors and Subsequent Prognosis in Patients With Cardiovascular Disease.

Journal article Can J Cardiol · October 2016 The role of psychological risk factors has been under-recognized in most subspecialties of medicine, as well as in general medicine practices. However, considerable evidence indicates that psychosocial factors are involved in the pathogenesis and progressi ... Full text Link to item Cite

Exploratory secondary analyses of a cognitive-behavioral intervention for knee osteoarthritis demonstrate reduction in biomarkers of adipocyte inflammation.

Journal article Osteoarthritis Cartilage · September 2016 OBJECTIVE: To investigate the effects of pain coping skills training (PCST) and a lifestyle behavioral weight management (BWM) program on inflammatory markers and biomarker associations with pain and function in the OA LIFE study. METHOD: Serum samples wer ... Full text Link to item Cite

Reactive hyperemia is associated with adverse clinical outcomes in heart failure.

Journal article Am Heart J · August 2016 INTRODUCTION: Impaired endothelial function, as assessed by brachial artery flow-mediated dilation (FMD), is an established risk factor for cardiovascular events. FMD is impaired in heart failure (HF) patients, but less is known about hyperemic brachial ar ... Full text Link to item Cite

Effects of Exercise and Sertraline on Measures of Coronary Heart Disease Risk in Patients With Major Depression: Results From the SMILE-II Randomized Clinical Trial.

Journal article Psychosom Med · June 2016 OBJECTIVE: To assess the effects of supervised and home-based aerobic exercise training, and antidepressant pharmacotherapy (sertraline) on coronary heart disease (CHD) risk factors in a sample of participants with major depressive disorder (MDD). METHODS: ... Full text Link to item Cite

Treatment of anxiety in patients with coronary heart disease: Rationale and design of the UNderstanding the benefits of exercise and escitalopram in anxious patients WIth coroNary heart Disease (UNWIND) randomized clinical trial.

Journal article Am Heart J · June 2016 BACKGROUND: Anxiety is highly prevalent among patients with coronary heart disease (CHD), and there is growing evidence that high levels of anxiety are associated with worse prognosis. However, few studies have evaluated the efficacy of treating anxiety in ... Full text Link to item Cite

Enhancing Cardiac Rehabilitation With Stress Management Training: A Randomized, Clinical Efficacy Trial.

Journal article Circulation · April 5, 2016 BACKGROUND: Cardiac rehabilitation (CR) is the standard of care for patients with coronary heart disease. Despite considerable epidemiological evidence that high stress is associated with worse health outcomes, stress management training (SMT) is not inclu ... Full text Link to item Cite

Dietary Factors and Cognitive Decline.

Journal article J Prev Alzheimers Dis · March 2016 Cognitive decline is an increasingly important public health problem, with more than 100 million adults worldwide projected to develop dementia by 2050. Accordingly, there has been an increased interest in preventive strategies that diminish this risk. It ... Full text Link to item Cite

Reduced Cerebral Perfusion Pressure during Lung Transplant Surgery Is Associated with Risk, Duration, and Severity of Postoperative Delirium.

Journal article Ann Am Thorac Soc · February 2016 RATIONALE: Delirium is common following lung transplant and is associated with poorer clinical outcomes. The extent to which intraoperative hemodynamic alterations may contribute to postoperative delirium among lung transplant recipients has not been exami ... Full text Link to item Cite

Biobehavioral Prognostic Factors in Chronic Obstructive Pulmonary Disease: Results From the INSPIRE-II Trial.

Journal article Psychosom Med · 2016 OBJECTIVE: To examine the prognostic value of select biobehavioral factors in patients with chronic obstructive pulmonary disease (COPD) in a secondary analysis of participants from the INSPIRE-II trial. METHODS: Three hundred twenty-six outpatients with C ... Full text Link to item Cite

Psychosocial Predictors of Mortality Following Lung Transplantation.

Journal article Am J Transplant · January 2016 Lung transplantation has become an increasingly common treatment for patients with end-stage lung disease. Few studies have examined psychosocial risk factors for mortality in transplant recipients, despite evidence suggesting that elevated levels of negat ... Full text Link to item Cite

Lifestyle modification for resistant hypertension: The TRIUMPH randomized clinical trial.

Journal article Am Heart J · November 2015 BACKGROUND: Resistant hypertension (RH) is a growing health burden in this country affecting as many as 1 in 5 adults being treated for hypertension. Resistant hypertension is associated with increased risk of adverse cardiovascular disease (CVD) events an ... Full text Link to item Cite

Endothelial function in postmenopausal women with nighttime systolic hypertension.

Journal article Menopause · August 2015 OBJECTIVE: Hypertension becomes more prevalent in women during their postmenopausal years. Nighttime systolic blood pressure (SBP) is especially predictive of adverse cardiac events, and the relationship between rising nighttime SBP and cardiovascular risk ... Full text Link to item Cite

Exercise as Treatment for Anxiety: Systematic Review and Analysis.

Journal article Ann Behav Med · August 2015 BACKGROUND: Exercise has been shown to reduce symptoms of anxiety, but few studies have studied exercise in individuals preselected because of their high anxiety. PURPOSE: The objective of this study is to review and critically evaluate studies of exercise ... Full text Link to item Cite

Development and psychometric properties of the Pulmonary-specific Quality-of-Life Scale in lung transplant patients.

Journal article J Heart Lung Transplant · August 2015 BACKGROUND: The Pulmonary-specific Quality-of-Life Scale (PQLS) was developed to measure quality of life (QoL) among patients awaiting lung transplant. The objective of this study was to determine the psychometric properties of the PQLS, identify empirical ... Full text Link to item Cite

Prognostic significance of depression in blacks with heart failure: insights from Heart Failure: a Controlled Trial Investigating Outcomes of Exercise Training.

Journal article Circ Heart Fail · May 2015 BACKGROUND: Although studies have shown that depression is associated with worse outcomes in patients with heart failure, most studies have been in white patients. The impact of depression on outcomes in blacks with heart failure has not been studied. METH ... Full text Link to item Cite

Cardiorespiratory fitness and cognitive function in midlife: neuroprotection or neuroselection?

Journal article Ann Neurol · April 2015 OBJECTIVE: A study was undertaken to determine whether better cognitive functioning at midlife among more physically fit individuals reflects neuroprotection, by which fitness protects against age-related cognitive decline, or neuroselection, by which chil ... Full text Open Access Link to item Cite

ENHANCING EXERCISE-BASED CARDIAC REHABILITATION WITH STRESS MANAGEMENT TRAINING

Journal article ANNALS OF BEHAVIORAL MEDICINE · April 1, 2015 Link to item Cite

Six-minute-walk distance and accelerometry predict outcomes in chronic obstructive pulmonary disease independent of Global Initiative for Chronic Obstructive Lung Disease 2011 Group.

Journal article Ann Am Thorac Soc · March 2015 RATIONALE: The 2011 combined Global Initiative for Chronic Obstructive Lung Disease (GOLD) assessment incorporates symptoms, exacerbation history, and spirometry in discriminating risk of exacerbations in patients with chronic obstructive pulmonary disease ... Full text Link to item Cite

Work and home stress: associations with anxiety and depression symptoms.

Journal article Occup Med (Lond) · March 2015 BACKGROUND: In the evolving work environment of global competition, the associations between work and home stress and psychological well-being are not well understood. AIMS: To examine the impact of psychosocial stress at work and at home on anxiety and de ... Full text Link to item Cite

Delirium affects length of hospital stay after lung transplantation.

Journal article J Crit Care · February 2015 BACKGROUND: Delirium is relatively common after lung transplantation, although its prevalence and prognostic significance have not been systematically studied. The purpose of the present study was to examine pretransplant predictors of delirium and the sho ... Full text Link to item Cite

Association of depressive and anxiety symptoms with 24-hour urinary catecholamines in individuals with untreated high blood pressure.

Journal article Psychosom Med · 2015 OBJECTIVE: Depression and anxiety are considered risk factors for cardiovascular disease (CVD). The explanatory mechanisms, however, are still to be characterized. One proposed pathophysiological pathway is dysregulation of the autonomic nervous system, in ... Full text Link to item Cite

Neurocognitive changes after lung transplantation.

Journal article Ann Am Thorac Soc · December 2014 RATIONALE: Neurocognitive impairments are associated with reduced quality of life and may adversely affect medical compliance, but their prevalence after lung transplantation has not been extensively studied. OBJECTIVES: To examine the frequency of neuroco ... Full text Link to item Cite

Exercise to combat depression.

Journal article JAMA · November 26, 2014 Full text Link to item Cite

The effects of a telehealth coping skills intervention on outcomes in chronic obstructive pulmonary disease: primary results from the INSPIRE-II study.

Journal article Psychosom Med · October 2014 OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is associated with increased morbidity and mortality and reduced quality of life (QoL). Novel interventions are needed to improve outcomes in COPD patients. The present study assessed the effects of a ... Full text Link to item Cite

Pain, physical functioning, and overeating in obese rheumatoid arthritis patients: do thoughts about pain and eating matter?

Journal article J Clin Rheumatol · August 2014 BACKGROUND: Obese rheumatoid arthritis (RA) patients have higher levels of pain, disability, and disease activity than do nonobese patients with RA. Patients' health-related thoughts about arthritis and weight may be important to consider in obese patients ... Full text Link to item Cite

Nocturnal patterns of heart rate and the risk of mortality after acute myocardial infarction.

Journal article Am Heart J · July 2014 BACKGROUND: The purposes of this study were to identify nocturnal patterns of heart rate (HR) in depressed and nondepressed patients after an acute myocardial infarction (MI) and to determine which patterns, if any, are associated with all-cause mortality ... Full text Link to item Cite

A Buddhist perspective on industrial engineering and the design of work.

Journal article Sci Eng Ethics · June 2014 The modern way of life is highly dependent upon the production of goods by industrial organizations that are in turn dependent upon their workers for their ongoing operations. Even though more than a century has passed since the dawn of the industrial revo ... Full text Link to item Cite

The long-term effects of lifestyle change on blood pressure: One-year follow-up of the ENCORE study.

Journal article Am J Hypertens · May 2014 BACKGROUND: There is a paucity of data describing the sustained benefits of lifestyle interventions on health behaviors and blood pressure (BP). METHODS: We examined the persistence of changes in health habits and BP in the ENCORE study, a trial in which 1 ... Full text Link to item Cite

NEUROPSYCHIATRIC OUTCOMES FOLLOWING LUNG TRANSPLANTATION

Journal article ANNALS OF BEHAVIORAL MEDICINE · April 1, 2014 Link to item Cite

Depression as a risk factor for poor prognosis among patients with acute coronary syndrome: systematic review and recommendations: a scientific statement from the American Heart Association.

Journal article Circulation · March 25, 2014 BACKGROUND: Although prospective studies, systematic reviews, and meta-analyses have documented an association between depression and increased morbidity and mortality in a variety of cardiac populations, depression has not yet achieved formal recognition ... Full text Link to item Cite

Neurobehavioral functioning and survival following lung transplantation.

Journal article Chest · March 1, 2014 BACKGROUND: Neurobehavioral functioning is widely recognized as being an important consideration in lung transplant candidates, but little is known about whether these factors are related to clinical outcomes. The present study examined the relationship of ... Full text Link to item Cite

Impact of sleep complaints and depression outcomes among participants in the standard medical intervention and long-term exercise study of exercise and pharmacotherapy for depression.

Journal article J Nerv Ment Dis · February 2014 The aim of this study was to examine the effects of exercise and sertraline on disordered sleep in patients with major depressive disorder (MDD). Methods The Standard Medical Intervention and Long-term Exercise study randomized the patients with MDD (n = 2 ... Full text Link to item Cite

The relationship between pain and eating among overweight and obese individuals with osteoarthritis: an ecological momentary study.

Journal article Pain Res Manag · 2014 BACKGROUND: Osteoarthritis (OA) patients who are overweight or obese report higher levels of pain compared with their normal-weight OA counterparts. Evidence suggests that overweight or obese OA patients also experience pain relief from eating foods high i ... Full text Link to item Cite

Letter to the editor.

Journal article J Electrocardiol · 2014 Full text Link to item Cite

Intraoperative magnesium administration does not improve neurocognitive function after cardiac surgery.

Journal article Stroke · December 2013 BACKGROUND AND PURPOSE: Neurocognitive decline occurs frequently after cardiac surgery and persists in a significant number of patients. Magnesium is thought to provide neuroprotection by preservation of cellular energy metabolism, blockade of the N-methyl ... Full text Link to item Cite

Impact of aerobic exercise on neurobehavioral outcomes.

Journal article Ment Health Phys Act · October 2013 Numerous studies have examined the relationship between physical activity and cognitive function, demonstrating that greater physical activity is associated with lower incidence of cognitive impairment in later life. Due to an increasingly large number of ... Full text Link to item Cite

Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease.

Journal article J Am Heart Assoc · March 19, 2013 BACKGROUND: Depression has been related to mortality in coronary heart disease (CHD) patients, but few studies have evaluated the role of anxiety or the role of the co-occurrence of depression and anxiety. We examined whether anxiety is associated with inc ... Full text Open Access Link to item Cite

Multi-scale heart rate dynamics detected by phase-rectified signal averaging predicts mortality after acute myocardial infarction.

Journal article Europace · March 2013 AIMS: Acceleration and deceleration capacity (AC and DC) for beat-to-beat short-term heart rate dynamics are powerful predictors of mortality after acute myocardial infarction (AMI). We examined if AC and DC for minute-order long-term heart rate dynamics a ... Full text Link to item Cite

Targeting lifestyle change in patients with depression.

Journal article J Am Coll Cardiol · February 12, 2013 Full text Link to item Cite

Psychosocial correlates of atrial natriuretic peptide: a marker of vascular health.

Journal article Ann Behav Med · February 2013 BACKGROUND: Psychosocial factors have been associated with cardiovascular outcomes, but few studies have examined the association between psychosocial function and natriuretic peptides. PURPOSE: The purpose of this study is to determine the predictive valu ... Full text Link to item Cite

A pilot test of an integrated self-care intervention for persons with heart failure and concomitant diabetes

Journal article Nursing Outlook · 2013 Studies show 30% to 47% of people with heart failure (HF) have concomitant diabetes mellitus (DM). Self-care for persons with both of these chronic conditions is conflicting, complex, and often inadequate. This pilot study tested an integrated self-care pr ... Full text Cite

A trial of family partnership and education interventions in heart failure

Journal article Journal of Cardiac Failure · 2013 Background Lowering dietary sodium and adhering to medication regimens are difficult for persons with heart failure (HF). Because these behaviors often occur within the family context, this study evaluated the effects of family education and partnership in ... Full text Cite

A trial of family partnership and education interventions in heart failure

Journal article Journal of Cardiac Failure · 2013 Background: Lowering dietary sodium and adhering to medication regimens are difficult for persons with heart failure (HF). Because these behaviors often occur within the family context, this study evaluated the effects of family education and partnership i ... Cite

The effect of job strain on nighttime blood pressure dipping among men and women with high blood pressure.

Journal article Scand J Work Environ Health · January 2013 OBJECTIVES: Blunted nighttime blood pressure dipping is an established cardiovascular risk factor. This study examined the effect of job strain on nighttime blood pressure dipping among men and women with high blood pressure. METHODS: The sample consisted ... Full text Link to item Cite

Can lifestyle modification improve neurocognition? Rationale and design of the ENLIGHTEN clinical trial.

Journal article Contemp Clin Trials · January 2013 BACKGROUND: Risk factors for cardiovascular disease (CVD) not only increase the risk for clinical CVD events, but also are associated with a cascade of neurophysiologic and neuroanatomic changes that increase the risk of cognitive impairment and dementia. ... Full text Link to item Cite

Association of anxiety and depression with pulmonary-specific symptoms in chronic obstructive pulmonary disease.

Journal article Int J Psychiatry Med · 2013 OBJECTIVES: To examine the association of anxiety and depression with pulmonary-specific symptoms of Chronic Obstructive Pulmonary Disease (COPD), and to determine the extent to which disease severity and functional capacity modify this association. METHOD ... Full text Link to item Cite

Reproducibility of blood pressure dipping: relation to day-to-day variability in sleep quality.

Journal article J Am Soc Hypertens · 2013 Previous studies of the reproducibility of blood pressure (BP) dipping have yielded inconsistent results. Few have examined factors that may influence day-to-day differences in dipping. Ambulatory BP monitoring was performed on three occasions, approximate ... Full text Link to item Cite

Reply

Journal article Journal of the American College of Cardiology · December 11, 2012 Full text Cite

The influence of endothelial function and myocardial ischemia on peak oxygen consumption in patients with coronary artery disease

Journal article International Journal of Vascular Medicine · November 19, 2012 Impaired endothelial function has been shown to limit exercise in coronary artery disease (CAD) patients and has been implicated in myocardial ischemia. However, the association of endothelial function and ischemia on peak exercise oxygen consumption (VO Full text Cite

Relation between volume of exercise and clinical outcomes in patients with heart failure.

Journal article J Am Coll Cardiol · November 6, 2012 OBJECTIVES: This study determined whether greater volumes of exercise were associated with greater reductions in clinical events. BACKGROUND: The HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) trial showed that am ... Full text Link to item Cite

Determinants and consequences of adherence to the dietary approaches to stop hypertension diet in African-American and white adults with high blood pressure: results from the ENCORE trial.

Journal article J Acad Nutr Diet · November 2012 BACKGROUND: Although the Dietary Approaches to Stop Hypertension (DASH) diet is an accepted nonpharmacologic treatment for hypertension, little is known about what patient characteristics affect dietary adherence and what level of adherence is needed to re ... Full text Link to item Cite

Nighttime blood pressure dipping in postmenopausal women with coronary heart disease.

Journal article Am J Hypertens · October 2012 BACKGROUND: Blunted nighttime blood pressure (BP) dipping is prognostic of cardiovascular morbidity and mortality. This relationship may be stronger among women than men. The present study hypothesized that coronary artery disease (CAD) and advancing age w ... Full text Link to item Cite

Interactive associations of depression and sleep apnea with adverse clinical outcomes after acute myocardial infarction.

Journal article Psychosom Med · October 2012 OBJECTIVE: Depression and sleep apnea (SA) are common among patients with a recent acute myocardial infarction (AMI), and both are associated with increased risk for adverse outcomes. We tested the hypothesis that there is an interaction between them in re ... Full text Link to item Cite

Exercise and pharmacological treatment of depressive symptoms in patients with coronary heart disease: results from the UPBEAT (Understanding the Prognostic Benefits of Exercise and Antidepressant Therapy) study.

Journal article J Am Coll Cardiol · September 18, 2012 OBJECTIVES: The aim of this study was to assess the efficacy of exercise and antidepressant medication in reducing depressive symptoms and improving cardiovascular biomarkers in depressed patients with coronary heart disease. BACKGROUND: Although there is ... Full text Link to item Cite

Changes in neurocognitive functioning following lung transplantation.

Journal article Am J Transplant · September 2012 Although neurocognitive impairment is relatively common among patients with advanced lung disease, little is known regarding changes in neurocognition following lung transplantation. We therefore administered 10 tests of neurocognitive functioning before a ... Full text Link to item Cite

Effects of exercise training on depressive symptoms in patients with chronic heart failure: the HF-ACTION randomized trial.

Journal article JAMA · August 1, 2012 CONTEXT: Depression is common in patients with cardiac disease, especially in patients with heart failure, and is associated with increased risk of adverse health outcomes. Some evidence suggests that aerobic exercise may reduce depressive symptoms, but to ... Full text Link to item Cite

Is Exercise a Viable Treatment for Depression?

Journal article ACSMs Health Fit J · July 2012 Depression is a common disorder that is associated with compromised quality of life, increased health care costs, and greater risk for a variety of medical conditions, particularly coronary heart disease. This review examines methods for assessing depressi ... Full text Link to item Cite

Polygenic risk, rapid childhood growth, and the development of obesity: evidence from a 4-decade longitudinal study.

Journal article Arch Pediatr Adolesc Med · June 1, 2012 OBJECTIVE: To test how genomic loci identified in genome-wide association studies influence the development of obesity. DESIGN: A 38-year prospective longitudinal study of a representative birth cohort. SETTING: The Dunedin Multidisciplinary Health and Dev ... Full text Link to item Cite

Pain coping skills training and lifestyle behavioral weight management in patients with knee osteoarthritis: a randomized controlled study.

Journal article Pain · June 2012 Overweight and obese patients with osteoarthritis (OA) experience more OA pain and disability than patients who are not overweight. This study examined the long-term efficacy of a combined pain coping skills training (PCST) and lifestyle behavioral weight ... Full text Link to item Cite

Sex differences in the endothelial function of untreated hypertension.

Journal article J Clin Hypertens (Greenwich) · April 2012 Vascular endothelial dysfunction is associated with increased risk for adverse cardiovascular (CV) events. However, less is known about sex differences in the endothelial function of untreated hypertensive individuals. The purpose of this study was to asse ... Full text Link to item Cite

THE ROLE OF EXERCISE IN THE SECONDARY PREVENTION OF DEPRESSION AND HEART DISEASE

Journal article ANNALS OF BEHAVIORAL MEDICINE · April 1, 2012 Link to item Cite

Linkages Between Facial Expressions of Anger and Transient Myocardial Ischemia in Men with Coronary Artery Disease

Journal article · March 22, 2012 This chapter examines linkages between spontaneous facial expressions of emotion and ischemia and examines the relative contributions of hostility and anger to a coronary heart disease-relevant outcome. The dynamic linkages between facial expressions of an ... Full text Cite

Should stress management be incorporated into cardiac rehabilitation?

Journal article Expert Rev Cardiovasc Ther · February 2012 Full text Link to item Cite

Stress and coping in caregivers of patients awaiting solid organ transplantation.

Journal article Clin Transplant · 2012 Caregivers for patients undergoing solid organ transplantation play an essential role in the process of transplantation. However, little is known about stress and coping among these caregivers. Six hundred and twenty-one primary caregivers of potential can ... Full text Link to item Cite

Ethnic differences in the effects of the DASH diet on nocturnal blood pressure dipping in individuals with high blood pressure.

Journal article Am J Hypertens · December 2011 BACKGROUND: Ethnic differences in nocturnal blood pressure (BP) dipping may contribute to the increased risk for adverse cardiovascular events noted in African Americans (AAs). The DASH (Dietary Approaches to Stop Hypertension) diet has been shown to be ef ... Full text Link to item Cite

Psychiatric and behavioral aspects of cardiovascular disease: epidemiology, mechanisms, and treatment.

Journal article Rev Esp Cardiol (Engl Ed) · October 2011 Psychosocial and behavioral factors, including mood (depression, anxiety, anger, and stress), personality (Type A, Type D, and hostility), and social support, are associated with both the development and progression of cardiovascular disease. "Negative" em ... Full text Link to item Cite

[Psychiatric and behavioral aspects of cardiovascular disease: epidemiology, mechanisms, and treatment].

Journal article Rev Esp Cardiol · October 2011 Psychosocial and behavioral factors, including mood (depression, anxiety, anger, and stress), personality (Type A, Type D, and hostility), and social support, are associated with both the development and progression of cardiovascular disease. "Negative" em ... Full text Link to item Cite

Blood pressure dipping: ethnicity, sleep quality, and sympathetic nervous system activity.

Journal article Am J Hypertens · September 2011 BACKGROUND: Blunted blood pressure (BP) dipping is an established predictor of adverse cardiovascular outcomes. Although blunted BP dipping is more common in African Americans than whites, the factors contributing to this ethnic difference are not well und ... Full text Link to item Cite

New frontiers in cardiovascular behavioral medicine: comparative effectiveness of exercise and medication in treating depression.

Journal article Cleve Clin J Med · August 2011 Exercise, considered a mainstay of cardiac rehabilitation, has been shown to reduce cardiac risk factors such as hyperlipidemia and hypertension. Growing evidence also suggests that exercise has beneficial effects on mental health, which is relevant for ca ... Full text Link to item Cite

Association of cortisol and the metabolic syndrome in Korean men and women.

Journal article J Korean Med Sci · July 2011 Obesity and the metabolic syndrome are closely related and have become increasingly prevalent in Korea. The cardiovascular disease (CVD) risk factors comprising the metabolic syndrome have previously been associated with increased hypothalamic-pituitary-ad ... Full text Link to item Cite

Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery.

Journal article Ann Thorac Surg · June 2011 BACKGROUND: Inclusion of a measure of left ventricular diastolic dysfunction (LVDD) may improve risk prediction after cardiac surgery. Current LVDD grading guidelines rely on echocardiographic variables that are not always available or aligned to allow gra ... Full text Link to item Cite

Association of vascular health and neurocognitive performance in overweight adults with high blood pressure.

Journal article J Clin Exp Neuropsychol · June 2011 The relationship between vascular health--including flow-mediated dilation (FMD) and intima medial thickness (IMT)--and neurocognitive performance was examined in a sample of 124 sedentary, middle-aged adults with high blood pressure (systolic blood pressu ... Full text Link to item Cite

Effects of coping skills training and sertraline in patients with non-cardiac chest pain: a randomized controlled study.

Journal article Pain · April 2011 Non-cardiac chest pain (NCCP) is a common and distressing condition. Prior studies suggest that psychotropic medication or pain coping skills training (CST) may benefit NCCP patients. To our knowledge, no clinical trials have examined the separate and comb ... Full text Link to item Cite

COMPARATIVE EFFECTIVENESS RESEARCH IN CARDIOVASCULAR BEHAVIORAL MEDICINE

Journal article ANNALS OF BEHAVIORAL MEDICINE · April 1, 2011 Link to item Cite

Coping effectively with heart failure (COPE-HF): design and rationale of a telephone-based coping skills intervention.

Journal article J Card Fail · March 2011 BACKGROUND: Coping Effectively with Heart Failure (COPE-HF) is an ongoing randomized clinical trial funded by the National Institutes of Health to evaluate if a coping skills training (CST) intervention will result in improved health status and quality of ... Full text Link to item Cite

The DASH diet and insulin sensitivity.

Journal article Curr Hypertens Rep · February 2011 Lifestyle modifications, including adoption of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, weight loss in individuals who are overweight or obese, and physical activity, are effective in the prevention and treatment of hypertension. ... Full text Link to item Cite

Worsening depressive symptoms are associated with adverse clinical outcomes in patients with heart failure.

Journal article J Am Coll Cardiol · January 25, 2011 OBJECTIVES: The purpose of this study was to assess the impact of changes in symptoms of depression over a 1-year period on subsequent clinical outcomes in heart failure (HF) patients. BACKGROUND: Emerging evidence shows that clinical depression, which is ... Full text Link to item Cite

Household responsibilities, income, and ambulatory blood pressure among working men and women.

Journal article Psychosom Med · 2011 OBJECTIVE: To test the hypothesis that a greater perceived responsibility for household tasks and a greater number of hours spent doing these tasks would be associated with elevated ambulatory systolic (SBP) and diastolic blood pressure (DBP). The connecti ... Full text Link to item Cite

Exercise and pharmacotherapy in patients with major depression: one-year follow-up of the SMILE study.

Journal article Psychosom Med · 2011 OBJECTIVE: To examine a 1-year follow-up of a 4-month, controlled clinical trial of exercise and antidepressant medication in patients with major depressive disorder (MDD). METHODS: In the original study, 202 sedentary adults with MDD were randomized to: a ... Full text Link to item Cite

Increased non-gaussianity of heart rate variability predicts cardiac mortality after an acute myocardial infarction.

Journal article Front Physiol · 2011 Non-Gaussianity index (λ) is a new index of heart rate variability (HRV) that characterizes increased probability of the large heart rate deviations from its trend. A previous study has reported that increased λ is an independent mortality predictor among ... Full text Link to item Cite

Management of depression in patients with coronary heart disease: association, mechanisms, and treatment implications for depressed cardiac patients.

Journal article Expert Opin Pharmacother · January 2011 IMPORTANCE OF THE FIELD: Coronary heart disease (CHD) and depression are two leading causes of death and disability in the United States and worldwide. Depression is especially common in cardiac patients, and there is growing evidence that depression is a ... Full text Link to item Cite

Risk factors: Anxiety and risk of cardiac events.

Journal article Nat Rev Cardiol · November 2010 Two recent studies published in the Journal of the American College of Cardiology report the prognostic significance of anxiety in the development of coronary heart disease in initially healthy adults. These findings are placed in the context of other publ ... Full text Link to item Cite

Cerebrovascular risk factors and cerebral hyperintensities among middle-aged and older adults with major depression.

Journal article Am J Geriatr Psychiatry · September 2010 OBJECTIVES: To examine the association between cerebral hyperintensities and cerebrovascular risk factors (CVRF) among middle-aged and older adults with major depressive disorder (MDD). METHODS: Thirty patients (aged 55-77 years) with MDD and no history of ... Full text Link to item Cite

Phobic anxiety and increased risk of mortality in coronary heart disease.

Journal article Psychosom Med · September 2010 OBJECTIVES: To evaluate whether phobic anxiety is associated with increased risk of cardiac mortality in individuals with established coronary heart disease (CHD) and to examine the role of reduced heart rate variability (HRV) in mediating this risk. Previ ... Full text Open Access Link to item Cite

Effects of the dietary approaches to stop hypertension diet, exercise, and caloric restriction on neurocognition in overweight adults with high blood pressure.

Journal article Hypertension · June 2010 High blood pressure increases the risks of stroke, dementia, and neurocognitive dysfunction. Although aerobic exercise and dietary modifications have been shown to reduce blood pressure, no randomized trials have examined the effects of aerobic exercise co ... Full text Open Access Link to item Cite

Effects of the dietary approaches to stop hypertension diet alone and in combination with exercise and caloric restriction on insulin sensitivity and lipids.

Journal article Hypertension · May 2010 This study examined the effects of the Dietary Approaches to Stop Hypertension (DASH) diet on insulin sensitivity and lipids. In a randomized control trial, 144 overweight (body mass index: 25 to 40) men (n=47) and women (n=97) with high blood pressure (13 ... Full text Link to item Cite

The lung cancer exercise training study: a randomized trial of aerobic training, resistance training, or both in postsurgical lung cancer patients: rationale and design.

Journal article BMC Cancer · April 21, 2010 BACKGROUND: The Lung Cancer Exercise Training Study (LUNGEVITY) is a randomized trial to investigate the efficacy of different types of exercise training on cardiorespiratory fitness (VO2peak), patient-reported outcomes, and the organ components that gover ... Full text Open Access Link to item Cite

Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials.

Journal article Psychosom Med · April 2010 OBJECTIVES: To assess the effects of aerobic exercise training on neurocognitive performance. Although the effects of exercise on neurocognition have been the subject of several previous reviews and meta-analyses, they have been hampered by methodological ... Full text Open Access Link to item Cite

SIX MINUTE WALK TEST PREDICTS DAILY ACTIVITY IN PATIENTS WITH COPD

Journal article ANNALS OF BEHAVIORAL MEDICINE · April 1, 2010 Link to item Cite

Cardiovascular hemodynamics during stress in premenopausal versus postmenopausal women.

Journal article Menopause · March 2010 OBJECTIVE: After menopause, women are at an increased risk of cardiovascular disease. The present study assessed cardiovascular hemodynamics in premenopausal versus postmenopausal women, with a focus on systemic vascular resistance (SVR) at rest and during ... Full text Link to item Cite

No laughing matter.

Journal article J Am Coll Cardiol · February 23, 2010 Full text Link to item Cite

Diet and neurocognition: review of evidence and methodological considerations.

Journal article Curr Aging Sci · February 2010 The relationship between diet and cognitive function has been a topic of increasing interest, as numerous studies have shown that variations in dietary practices and nutrient intake may protect against age-related cognitive decline, as well as the developm ... Full text Link to item Cite

Effects of the DASH diet alone and in combination with exercise and weight loss on blood pressure and cardiovascular biomarkers in men and women with high blood pressure: the ENCORE study.

Journal article Arch Intern Med · January 25, 2010 BACKGROUND: Although the DASH (Dietary Approaches to Stop Hypertension) diet has been shown to lower blood pressure (BP) in short-term feeding studies, it has not been shown to lower BP among free-living individuals, nor has it been shown to alter cardiova ... Full text Link to item Cite

Cardiovascular disease risk, vascular health and erectile dysfunction among middle-aged, clinically depressed men.

Journal article Int J Impot Res · 2010 Erectile dysfunction (ED) is especially common in men with major depressive disorder (MDD). This study examined the extent to which risk factors for cardiovascular disease (CVD) and vascular endothelial dysfunction were associated with ED severity in MDD p ... Full text Link to item Cite

Prognosis after change in left ventricular ejection fraction during mental stress testing in patients with stable coronary artery disease.

Journal article Am J Cardiol · January 1, 2010 Previous studies of patients with stable coronary artery disease have demonstrated that decreases in the left ventricular ejection fraction (LVEF) during acute mental stress are predictive of adverse clinical outcomes. The aim of the present study was to e ... Full text Link to item Cite

Enhancing standard cardiac rehabilitation with stress management training: background, methods, and design for the enhanced study.

Journal article J Cardiopulm Rehabil Prev · 2010 PURPOSE: Enhancing Standard Cardiac Rehabilitation with Stress Management Training in Patients with Heart Disease (ENHANCED) is a randomized clinical trial funded by the National Heart Lung and Blood Institute to evaluate the effects of stress management t ... Full text Link to item Cite

Pain catastrophizing in patients with noncardiac chest pain: relationships with pain, anxiety, and disability.

Journal article Psychosom Med · October 2009 OBJECTIVE: To examine the contributions of chest pain, anxiety, and pain catastrophizing to disability in 97 patients with noncardiac chest pain (NCCP) and to test whether chest pain and anxiety were related indirectly to greater disability via pain catast ... Full text Link to item Cite

Coping styles in heart failure patients with depressive symptoms.

Journal article J Psychosom Res · October 2009 OBJECTIVE: Elevated depressive symptoms have been linked to poorer prognosis in heart failure (HF) patients. Our objective was to identify coping styles associated with depressive symptoms in HF patients. METHODS: A total of 222 stable HF patients (32.75% ... Full text Link to item Cite

Effects of aerobic exercise on sexual functioning in depressed adults

Journal article Mental Health and Physical Activity · June 1, 2009 Objective: Exercise appears to be generally comparable to antidepressant medication in reducing depressive symptoms. The current study examines the effects of aerobic exercise, compared to antidepressant medication and placebo pill, on sexual function amon ... Full text Cite

Pain catastrophizing and pain-related fear in osteoarthritis patients: relationships to pain and disability.

Journal article J Pain Symptom Manage · May 2009 This study examined the degree to which pain catastrophizing and pain-related fear explain pain, psychological disability, physical disability, and walking speed in patients with osteoarthritis (OA) of the knee. Participants in this study were 106 individu ... Full text Link to item Cite

Association between n-3 fatty acid consumption and ventricular ectopy after myocardial infarction.

Journal article Am J Clin Nutr · May 2009 BACKGROUND: n-3 (omega-3) Fatty acids are associated with a reduced risk of cardiovascular disease; however, the relation between dietary intake of n-3 fatty acids and ventricular arrhythmias has not been investigated among acute post-myocardial infarction ... Full text Link to item Cite

Relation of depression to severity of illness in heart failure (from Heart Failure And a Controlled Trial Investigating Outcomes of Exercise Training [HF-ACTION]).

Journal article Am J Cardiol · May 1, 2009 Depression is common in patients with heart failure (HF), prognostic for adverse outcomes and purportedly related to disease severity. Psychological and physiologic factors relevant to HF were assessed in HF-ACTION, a large randomized study of aerobic exer ... Full text Link to item Cite

Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial.

Journal article JAMA · April 8, 2009 CONTEXT: Findings from previous studies of the effects of exercise training on patient-reported health status have been inconsistent. OBJECTIVE: To test the effects of exercise training on health status among patients with heart failure. DESIGN, SETTING, A ... Full text Link to item Cite

Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial.

Journal article JAMA · April 8, 2009 CONTEXT: Guidelines recommend that exercise training be considered for medically stable outpatients with heart failure. Previous studies have not had adequate statistical power to measure the effects of exercise training on clinical outcomes. OBJECTIVE: To ... Full text Link to item Cite

Caregiver-assisted coping skills training for patients with COPD: background, design, and methodological issues for the INSPIRE-II study.

Journal article Clin Trials · April 2009 BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a progressive illness characterized by airflow obstruction and dyspnea that afflicts over 12 million people and represents a leading cause of death in the United States. Not surprisingly, COPD is ... Full text Link to item Cite

History of depression and survival after acute myocardial infarction.

Journal article Psychosom Med · April 2009 OBJECTIVE: To compare survival in post-myocardial (MI) participants from the Enhancing Recovery In Coronary Heart Disease (ENRICHD) clinical trial with a first episode of major depression (MD) and those with recurrent MD, which is a risk factor for mortali ... Full text Link to item Cite

Obesity among those with mental disorders: a National Institute of Mental Health meeting report.

Journal article Am J Prev Med · April 2009 The National Institute of Mental Health convened a meeting in October 2005 to review the literature on obesity, nutrition, and physical activity among those with mental disorders. The findings of this meeting and subsequent update of the literature review ... Full text Link to item Cite

Randomized, double-blinded, placebo controlled study of neuroprotection with lidocaine in cardiac surgery.

Journal article Stroke · March 2009 BACKGROUND AND PURPOSE: Cognitive decline after cardiac surgery remains common and diminishes patients' quality of life. Based on experimental and clinical evidence, this study assessed the potential of intravenously administered lidocaine to reduce postop ... Full text Link to item Cite

AHA science advisory. Depression and coronary heart disease. Recommendations for screening, referral, and treatment. A science advisory from the American Heart Association Prevention Committee to the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care Outcomes Research. Endorsed by the American Psychiatric Association.

Journal article Prog Cardiovasc Nurs · March 2009 Depression is commonly present in patients with coronary heart disease (CHD) and is independently associated with increased cardiovascular morbidity and mortality. Screening tests for depressive symptoms should be applied to identify patients who may requi ... Full text Link to item Cite

Intima-media thickness and age of first depressive episode.

Journal article Biol Psychol · March 2009 BACKGROUND: Late life depression, including patients with vascular depression, has been associated with higher levels of intima-media thickness (IMT). Although individuals with vascular depression tend to report a later onset of depression, the relationshi ... Full text Link to item Cite

Ethnic differences in the treatment of depression in patients with ischemic heart disease.

Journal article Am Heart J · January 2009 OBJECTIVE: The aim of this study is to examine ethnic differences in depressive symptoms and antidepressant treatment in a cohort of patients undergoing diagnostic coronary angiography. BACKGROUND: Coronary heart disease (CHD) is the leading cause of morta ... Full text Link to item Cite

Dimensions of social support and depression in patients at increased psychosocial risk recovering from myocardial infarction.

Journal article Int J Behav Med · 2009 BACKGROUND: There is considerable evidence that depression and low social support are associated with increased morbidity and mortality for patients with coronary heart disease (CHD). However, there is a lack of consensus regarding the measurement of socia ... Full text Link to item Cite

Independent prognostic value of echocardiography and N-terminal pro-B-type natriuretic peptide in patients with heart failure.

Journal article Am Heart J · December 2008 BACKGROUND: Echocardiographic indices of cardiac structure and function and natriuretic peptide levels are strong predictors of mortality in patients with heart failure. Whether cardiac ultrasound and natriuretic peptides provide independent prognostic inf ... Full text Link to item Cite

Relationship of genetic variability and depressive symptoms to adverse events after coronary artery bypass graft surgery.

Journal article Psychosom Med · November 2008 OBJECTIVE: To assess genetic variability in two serotonin-related gene polymorphisms (MAOA-uVNTR and 5HTTLPR) and their relationships to depression and adverse cardiac events in a sample of patients undergoing coronary artery bypass surgery. METHODS: A tot ... Full text Link to item Cite

Depression and coronary heart disease: recommendations for screening, referral, and treatment: a science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Psychiatric Association.

Journal article Circulation · October 21, 2008 Depression is commonly present in patients with coronary heart disease (CHD) and is independently associated with increased cardiovascular morbidity and mortality. Screening tests for depressive symptoms should be applied to identify patients who may requi ... Full text Link to item Cite

Domain specific self-efficacy mediates the impact of pain catastrophizing on pain and disability in overweight and obese osteoarthritis patients.

Journal article J Pain · October 2008 UNLABELLED: This study examined whether self-efficacy mediated the relationship between pain catastrophizing and pain and disability. Participants were 192 individuals diagnosed with osteoarthritis (OA) of the knees who were overweight or obese. Multiple m ... Full text Link to item Cite

Nighttime heart rate and survival in depressed patients post acute myocardial infarction.

Journal article Psychosom Med · September 2008 OBJECTIVES: To determine if: 1) depressed patients with a recent acute myocardial infarction (AMI) have higher nighttime heart rate (HR) than nondepressed patients, and 2) elevated nighttime HR is associated with decreased survival post AMI. Depression is ... Full text Link to item Cite

Depression and five year survival following acute myocardial infarction: a prospective study.

Journal article J Affect Disord · July 2008 Featured Publication Depression has been shown to be a risk factor for mortality during the 12 months following an acute myocardial infarction (MI), but few studies have examined whether it is associated with increased risk over longer periods. Most of the existing studies uti ... Full text Link to item Cite

Baseline 6-min walk distance predicts survival in lung transplant candidates.

Journal article Am J Transplant · July 2008 In a large, prospectively followed, two-center cohort of patients listed for lung transplantation (n = 376), we used Cox proportional hazards models to determine the importance of baseline 6-min walk distance (6MWD) in predicting patient survival. 6MWD use ... Full text Link to item Cite

Coping and quality of life in patients awaiting lung transplantation.

Journal article J Psychosom Res · July 2008 OBJECTIVE: Patients with end-stage lung disease (ESLD) experience significant decrements in quality of life (QOL). Although coping strategies are related to QOL in patients with ESLD, the extent to which specific native lung disease moderates this relation ... Full text Link to item Cite

Exercise fails to improve neurocognition in depressed middle-aged and older adults.

Journal article Med Sci Sports Exerc · July 2008 PURPOSE: Although cross-sectional studies have demonstrated an association between higher levels of aerobic fitness and improved neurocognitive function, there have been relatively few interventional studies investigating this relationship, and results hav ... Full text Link to item Cite

Arthritis self-efficacy and self-efficacy for resisting eating: relationships to pain, disability, and eating behavior in overweight and obese individuals with osteoarthritic knee pain.

Journal article Pain · June 2008 Featured Publication This study examined arthritis self-efficacy and self-efficacy for resisting eating as predictors of pain, disability, and eating behaviors in overweight or obese patients with osteoarthritis (OA) of the knee. Patients (N=174) with a body mass index between ... Full text Link to item Cite

Laboratory-based blood pressure recovery is a predictor of ambulatory blood pressure.

Journal article Biol Psychol · March 2008 Featured Publication The recovery phase of the stress response is an individual difference characteristic that may predict cardiovascular risk. The purpose of this study was to examine whether laboratory-based blood pressure (BP) recovery predicts ambulatory BP (ABP). One hund ... Full text Link to item Cite

Depression and coronary heart disease: association and implications for treatment.

Journal article Cleve Clin J Med · March 2008 Growing evidence indicates that depression is an important primary and secondary risk factor for coronary heart disease (CHD). Depression is quite common among patients with CHD: prevalence estimates are 14% or higher, and an additional 20% of patients hav ... Full text Link to item Cite

C-reactive protein and heart rate variability following myocardial infarction

Journal article ANNALS OF BEHAVIORAL MEDICINE · March 1, 2008 Link to item Cite

Response to letters to the editor [3]

Journal article Psychosomatic Medicine · February 1, 2008 Full text Cite

In Response

Journal article Health Psychology · January 1, 2008 Full text Cite

Effects of exercise and weight loss on depressive symptoms among men and women with hypertension.

Journal article J Psychosom Res · November 2007 Featured Publication OBJECTIVE: This study aimed to investigate changes in depressive symptoms in hypertensive individuals participating in an exercise and weight loss intervention. METHODS: This study involved 133 sedentary men and women with high blood pressure (BP; 130-180 ... Full text Link to item Cite

Effects of extreme hemodilution during cardiac surgery on cognitive function in the elderly.

Journal article Anesthesiology · October 2007 Featured Publication BACKGROUND: Strategies for neuroprotection including hypothermia and hemodilution have been routinely practiced since the inception of cardiopulmonary bypass. Yet postoperative neurocognitive deficits that diminish the quality of life of cardiac surgery pa ... Full text Link to item Cite

Age moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women.

Journal article Arterioscler Thromb Vasc Biol · August 2007 Featured Publication OBJECTIVE: We evaluated age and coronary heart disease (CHD) as potential moderators of the effects of 17beta-estradiol on vascular endothelial function in postmenopausal women. METHODS AND RESULTS: In a double-blind crossover design, 100 postmenopausal wo ... Full text Link to item Cite

Social support and prognosis in patients at increased psychosocial risk recovering from myocardial infarction.

Journal article Health Psychol · July 2007 Featured Publication OBJECTIVE: To compare the impact of network support and different types of perceived functional support on all-cause mortality or nonfatal reinfarction for patients with a recent acute myocardial infarction (AMI). DESIGN: Participants were recruited from t ... Full text Link to item Cite

Genetic variants in P-selectin and C-reactive protein influence susceptibility to cognitive decline after cardiac surgery.

Journal article J Am Coll Cardiol · May 15, 2007 Featured Publication OBJECTIVES: We hypothesized that candidate gene polymorphisms in biologic pathways regulating inflammation, cell matrix adhesion/interaction, coagulation-thrombosis, lipid metabolism, and vascular reactivity are associated with postoperative cognitive defi ... Full text Link to item Cite

Relationship of depression to death or hospitalization in patients with heart failure.

Journal article Arch Intern Med · February 26, 2007 Featured Publication BACKGROUND: Depression is widely recognized as a risk factor in patients with coronary heart disease. However, patients with heart failure (HF) have been less frequently studied, and the effect of depression on prognosis, independent of disease severity, i ... Full text Link to item Cite

Heart failure and a controlled trial investigating outcomes of exercise training (HF-ACTION): design and rationale.

Journal article Am Heart J · February 2007 Featured Publication BACKGROUND: Although there are limited clinical data to support the use of exercise training as a means to reduce mortality and morbidity in patients with heart failure, current guidelines state that exercise is beneficial. TRIAL DESIGN: The objective of t ... Full text Link to item Cite

Psychosocial training and cardiac rehabilitation.

Journal article J Cardiopulm Rehabil Prev · 2007 Featured Publication Full text Link to item Cite

Heart rate turbulence, depression, and survival after acute myocardial infarction.

Journal article Psychosom Med · January 2007 Featured Publication OBJECTIVE: Depression is a risk factor for mortality after acute myocardial infarction (AMI), possibly as a result of altered autonomic nervous system (ANS) modulation of heart rate (HR) and rhythm. The purposes of this study were to determine: a) whether ... Full text Link to item Cite

Donepezil for cognitive decline following coronary artery bypass surgery: a pilot randomized controlled trial.

Journal article Psychopharmacol Bull · 2007 Featured Publication OBJECTIVE: To study the effect of donepezil in treating patients with cognitive decline following coronary artery bypass graft (CABG) surgery. METHODS: Forty-four patients, with at least a 0.5 SD decline at 1 year post-CABG on at least one cognitive domain ... Link to item Cite

Spirituality, religion, and clinical outcomes in patients recovering from an acute myocardial infarction.

Journal article Psychosom Med · 2007 Featured Publication OBJECTIVE: To assess the prospective relationship between spiritual experiences and health in a sample of patients surviving an acute myocardial infarction (AMI) with depression or low social support. METHODS: A subset of 503 patients participating in the ... Full text Link to item Cite

Exercise as a treatment for depression and other psychiatric disorders: a review.

Journal article J Cardiopulm Rehabil Prev · 2007 Featured Publication This article reviews evidence supporting exercise as a treatment for psychiatric disorders. Although data from randomized trials are limited, results of studies included in this review generally support use of exercise as an alternative or adjunctive treat ... Full text Link to item Cite

Exercise and pharmacotherapy in the treatment of major depressive disorder.

Journal article Psychosom Med · 2007 Featured Publication OBJECTIVE: To assess whether patients receiving aerobic exercise training performed either at home or in a supervised group setting achieve reductions in depression comparable to standard antidepressant medication (sertraline) and greater reductions in dep ... Full text Link to item Cite

Ventricular ectopy: impact of self-reported stress after myocardial infarction.

Journal article Am Heart J · January 2007 Featured Publication BACKGROUND: Although psychologic stress has been implicated in the pathogenesis of ventricular arrhythmias, the relationship between self-reported stress and ventricular ectopy has not been evaluated under naturalistic conditions in acute post-myocardial i ... Full text Link to item Cite

Understanding prognostic benefits of exercise and antidepressant therapy for persons with depression and heart disease: the UPBEAT study--rationale, design, and methodological issues.

Journal article Clin Trials · 2007 Featured Publication BACKGROUND: Depression is relatively common in patients with coronary heart disease (CHD) and is associated with worse prognosis. Recently there has been interest in evaluating the impact of treating depression on clinical outcomes. Anti-depressant medicat ... Full text Link to item Cite

Cerebrovascular risk factors, vascular disease, and neuropsychological outcomes in adults with major depression.

Journal article Psychosom Med · 2007 Featured Publication OBJECTIVE: To investigate the relationship of cerebrovascular risk factors (CVRFs), endothelial function, carotid artery intima medial thickness (IMT), and neuropsychological performance in a sample of 198 middle-aged and older individuals with major depre ... Full text Link to item Cite

Exercise

Journal article · January 1, 2007 Regular physical exercise improves muscle strength and cardiorespiratory endurance. In addition, exercise reduces symptoms of depression and anxiety, attenuates cardiovascular and neurohumoral stress responses, and may also improve neurocognition. A number ... Full text Cite

Central nervous system injury associated with cardiac surgery.

Journal article Lancet · August 19, 2006 Featured Publication Millions of individuals with coronary artery or valvular heart disease have been given a new chance at life by heart surgery, but the potential for neurological injury is an Achilles heel. Technological advancements and innovations in surgical and anaesthe ... Full text Link to item Cite

Changes in plasma volume associated with mental stress ischemia in patients with coronary artery disease.

Journal article Int J Psychophysiol · August 2006 Featured Publication Psychological stress has been shown to trigger angina and myocardial ischemia in patients with coronary artery disease. However, the mechanisms by which stress may trigger cardiac events has yet to be fully elucidated. Twenty five patients underwent radion ... Full text Link to item Cite

Prediction of medical morbidity and mortality after acute myocardial infarction in patients at increased psychosocial risk in the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) study.

Journal article Am Heart J · July 2006 Featured Publication BACKGROUND: Patients with myocardial infarction (MI) are at further increased risk for untoward events when patients also exhibit low social support and/or depression. The ENRICHD study was the largest controlled trial in post-MI patients attempting to tre ... Full text Link to item Cite

Telephone-based coping skills training for patients awaiting lung transplantation.

Journal article J Consult Clin Psychol · June 2006 Featured Publication Impaired quality of life is associated with increased mortality in patients with advanced lung disease. Using a randomized controlled trial with allocation concealment and blinded outcome assessment at 2 tertiary care teaching hospitals, the authors random ... Full text Link to item Cite

Psychosocial issues in the assessment and management of patients undergoing lung transplantation.

Journal article Chest · May 2006 Featured Publication This review examines psychosocial issues among lung transplant patients from the time of assessment through the posttransplant period. Although psychological factors are recognized as being important in the transplant evaluation, no standard approach to ps ... Full text Link to item Cite

Successful bilateral lung transplant outcomes in recipients 61 years of age and older.

Journal article Transplantation · March 27, 2006 Featured Publication BACKGROUND: Controversy exists regarding the optimal use of bilateral lung transplant (BLT) in older recipients in diseases where either single or bilateral transplant is appropriate. International Society for Heart and Lung Transplant (ISHLT) guidelines s ... Full text Link to item Cite

Cardiac Rehabilitation, Exercise Training, and Psychosocial Risk Factors: Reply

Journal article Journal of the American College of Cardiology · January 2006 Full text Cite

The effect of a psychosocial intervention and quality of life after acute myocardial infarction

Journal article Journal of Cardiopulmonary Rehabilitation · 2006 Cite

Phobic anxiety, depression, and risk of ventricular arrhythmias in patients with coronary heart disease.

Journal article Psychosom Med · 2006 Featured Publication OBJECTIVE: Findings of an association between phobic anxiety and elevated risks of sudden cardiac death suggest that phobic anxiety may be related to increased risk of ventricular arrhythmias. The purpose of this study was to examine whether phobic anxiety ... Full text Link to item Cite

The effect of a psychosocial intervention and quality of life after acute myocardial infarction: the Enhancing Recovery in Coronary Heart Disease (ENRICHD) clinical trial.

Journal article J Cardiopulm Rehabil · 2006 Featured Publication PURPOSE: The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) clinical trial was designed to test whether intervening on depression or low perceived social support reduces mortality and reinfarction in patients with acute myocardial infarcti ... Full text Link to item Cite

Association of neurocognitive function and quality of life 1 year after coronary artery bypass graft (CABG) surgery.

Journal article Psychosom Med · 2006 Featured Publication OBJECTIVE: Although coronary artery bypass grafting (CABG) has been shown to improve quality of life and functional capacity for many patients, recent studies have demonstrated that a significant number of patients exhibit impairment in cognitive function ... Full text Link to item Cite

Association between hot flashes, sleep complaints, and psychological functioning among healthy menopausal women.

Journal article Int J Behav Med · 2006 Featured Publication Self-report data suggest that sleep hot flashes among menopausal women are associated with sleep problems and in turn impaired psychological functioning. However, few studies have examined these relations with physiologic hot flash measures. A total of 41 ... Full text Link to item Cite

Exercise training and depression in older adults.

Journal article Neurobiol Aging · December 2005 Featured Publication This article provides a review of the evidence supporting exercise as an effective treatment of depression in older adults. Depression is prevalent among older adults and is associated with significant morbidity, increased risk of mortality, and economic b ... Full text Link to item Cite

September 11, 2001, revisited: a review of the data.

Journal article Arch Surg · November 2005 Featured Publication HYPOTHESIS: The September 11, 2001, World Trade Center (WTC) attack was a disaster of epic proportion in New York City, NY. It was unprecedented in terms of the number of people who were killed in the bombings, as well as in terms of the volume of patients ... Full text Link to item Cite

10-Year review of knee dislocations: Is arteriography always necessary? Discussion

Journal article JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE · September 2005 Link to item Cite

Impaired endothelial function in coronary heart disease patients with depressive symptomatology.

Journal article J Am Coll Cardiol · August 16, 2005 Featured Publication OBJECTIVES: The purpose of this study was to assess whether depressive symptomatology was associated with vascular endothelial dysfunction in patients with coronary heart disease (CHD). BACKGROUND: In patients with CHD, the presence of depression is associ ... Full text Link to item Cite

Low heart rate variability and the effect of depression on post-myocardial infarction mortality.

Journal article Arch Intern Med · July 11, 2005 Featured Publication BACKGROUND: Depression is associated with an increased risk for mortality after acute myocardial infarction (MI). The purpose of this study was to determine whether low heart rate variability (HRV) mediates the effect of depression on mortality. METHODS: T ... Full text Link to item Cite

Effects of antidepressant medication on morbidity and mortality in depressed patients after myocardial infarction.

Journal article Arch Gen Psychiatry · July 2005 Featured Publication BACKGROUND: Depression after myocardial infarction (MI) is associated with higher morbidity and mortality. Although antidepressants are effective in reducing depression, their use in patients with cardiovascular disease remains controversial. OBJECTIVE: To ... Full text Link to item Cite

Emotional distress and quality of life in caregivers of patients awaiting lung transplant.

Journal article J Psychosom Res · July 2005 Featured Publication OBJECTIVE: The aims of this study are to characterize the levels of emotional distress and quality of life among caregivers of lung transplant candidates and to examine the relation of coping styles and perceived caregiver burden to caregivers' self-report ... Full text Link to item Cite

Depression and heart failure in patients with a new myocardial infarction.

Journal article Am Heart J · May 2005 Featured Publication BACKGROUND: Heart failure (HF) is a disabling chronic illness that is increasing in prevalence. Despite advances in its medical treatment, little is known about its psychosocial correlates. This investigation compared the prevalence of depression in patien ... Full text Link to item Cite

Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease: a randomized controlled trial.

Journal article JAMA · April 6, 2005 Featured Publication CONTEXT: Observational studies have shown that psychosocial factors are associated with increased risk for cardiovascular morbidity and mortality, but the effects of behavioral interventions on psychosocial and medical end points remain uncertain. OBJECTIV ... Full text Link to item Cite

The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology.

Journal article J Am Coll Cardiol · March 1, 2005 Featured Publication Observational studies indicate that psychologic factors strongly influence the course of coronary artery disease (CAD). In this review, we examine new epidemiologic evidence for the association between psychosocial risk factors and CAD, identify pathologic ... Full text Link to item Cite

Depressive symptoms in heart transplant recipients in an alternate list program

Journal article The Journal of Heart and Lung Transplantation · 2005 Cite

Gas exchange and exercise capacity affect neurocognitive performance in patients with lung disease.

Journal article Psychosom Med · 2005 Featured Publication OBJECTIVE: This study examined the relationship between cognitive functioning and the severity of underlying lung disease in patients awaiting lung transplantation. METHODS: Ninety-four patients with end-stage lung disease completed a test battery to asses ... Full text Link to item Cite

Nonpharmacologic treatments for depression in patients with coronary heart disease.

Journal article Psychosom Med · 2005 Featured Publication OBJECTIVES: We review nonpharmacologic treatments for depression in patients with coronary heart disease (CHD), including psychological therapies such as cognitive behavior therapy (CBT) and interpersonal therapy (IPT), aerobic exercise, St. John's wort (S ... Full text Link to item Cite

Depression and cardiac risk.

Journal article J Cardiopulm Rehabil · 2005 Featured Publication Full text Link to item Cite

Social support and coronary heart disease: epidemiologic evidence and implications for treatment.

Journal article Psychosom Med · 2005 Featured Publication OBJECTIVE: The present paper reviews theories of social support and evidence for the role of social support in the development and progression of coronary heart disease (CHD). METHODS: Articles for the primary review of social support as a risk factor were ... Full text Link to item Cite

Emotional antecedents of hot flashes during daily life.

Journal article Psychosom Med · 2005 Featured Publication OBJECTIVE: Hot flashes are among the most frequently reported menopausal symptoms. However, little is known about factors associated with their occurrence. Moreover, despite the wide use of self-report hot flash measures, little is known about their concor ... Full text Link to item Cite

Social support and religiosity as coping strategies for anxiety in hospitalized cardiac patients.

Journal article Ann Behav Med · December 2004 Featured Publication BACKGROUND: Prospective studies have demonstrated that anxiety is associated with an increased risk of mortality and sudden cardiac death. There is therefore a need to understand what factors contribute to anxiety in patients with coronary heart disease (C ... Full text Link to item Cite

Fixing the heart: must the brain pay the price?

Journal article Circulation · November 30, 2004 Featured Publication Full text Link to item Cite

Association between exercise capacity and left ventricular geometry in overweight patients with mild systemic hypertension.

Journal article Am J Cardiol · November 15, 2004 Featured Publication The purpose of this study was to determine the relation between left ventricular (LV) geometry and exercise capacity in unmedicated, hypertensive patients. Analysis of the data revealed peak oxygen consumption (ml kg(-1) min(-1)) for concentric hypertrophy ... Full text Link to item Cite

Cognitive deficits following coronary artery bypass grafting: prevalence, prognosis, and therapeutic strategies.

Journal article CNS Spectr · October 2004 Featured Publication There is increasing recognition that coronary artery bypass grafting (CABG) may be a risk factor for subtle cognitive decline although the presence and pattern of such decline has varied across studies. Cognitive deficits may present as short-term memory l ... Full text Link to item Cite

Depression and anxiety symptoms are related to increased 24-hour urinary norepinephrine excretion among healthy middle-aged women.

Journal article J Psychosom Res · October 2004 Featured Publication OBJECTIVE: Depression is a risk factor for morbidity and mortality in a variety of populations, and anxiety has also been associated with risk of mortality among cardiac patients. Dysfunction of the autonomic nervous system may be involved in this risk. Th ... Full text Link to item Cite

Effects of spouse-assisted coping skills training and exercise training in patients with osteoarthritic knee pain: a randomized controlled study.

Journal article Pain · August 2004 This study tested the separate and combined effects of spouse-assisted pain coping skills training (SA-CST) and exercise training (ET) in a sample of patients having persistent osteoarthritic knee pain. Seventy-two married osteoarthritis (OA) patients with ... Full text Link to item Cite

Depression as a risk factor for post-MI mortality.

Journal article J Am Coll Cardiol · July 21, 2004 Featured Publication Full text Link to item Cite

Effects of daily stress on autonomic cardiac control in patients with coronary artery disease.

Journal article Am J Cardiol · May 15, 2004 Featured Publication Emotional stress has been implicated in the development and progression of coronary artery disease, with 1 proposed causal pathway being changes in cardiac autonomic tone. One hundred thirty-five patients with coronary artery disease underwent 48 hours of ... Full text Link to item Cite

Exercise, depression, and mortality after myocardial infarction in the ENRICHD trial.

Journal article Med Sci Sports Exerc · May 2004 Featured Publication PURPOSE: The large and well-characterized population of acute myocardial infarction (AMI) patients studied in the recently completed Enhancing Recovery in Coronary Heart Disease (ENRICHD) multicenter clinical trial provides a unique opportunity to examine ... Full text Link to item Cite

Health psychology: what will the future bring?

Journal article Health Psychol · March 2004 Featured Publication This commentary highlights several important themes and trends in this series of articles focusing on the future of health psychology. First, the challenges posed by changes in populations will only be met if health psychologists can develop a contextual c ... Full text Link to item Cite

Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients.

Journal article J Hypertens · February 2004 Featured Publication OBJECTIVE: To examine the association between the graded exercise systolic blood pressure (SBP) response and left ventricular (LV) geometric structure in patients with untreated mild hypertension. PARTICIPANTS: The study included 80 sedentary, overweight p ... Full text Link to item Cite

Effects of exercise, diet and weight loss on high blood pressure

Journal article American Journal of Hypertension · 2004 Cite

The effects of daily stress on autonomic cardiac

Journal article American Journal of Cardiology · 2004 Cite

Depression and late mortality after myocardial infarction in the Enhancing Recovery in Coronary Heart Disease (ENRICHD) study.

Journal article Psychosom Med · 2004 Featured Publication OBJECTIVE: The Enhancing Recovery in Coronary Heart Disease study was a multicenter clinical trial in which patients with depression and/or low perceived social support after an acute myocardial infarction were randomly assigned to an intervention consisti ... Full text Link to item Cite

Effects of exercise, diet and weight loss on high blood pressure.

Journal article Sports Med · 2004 Featured Publication High blood pressure (BP) is a major health problem in the US, affecting more than 50 million people. Although high BP is among the most common reasons for outpatient visits, BP control is often inadequate. It is well established that BP can be lowered phar ... Full text Link to item Cite

Ethnic differences in left ventricular structure: relations to hemodynamics and diurnal blood pressure variation.

Journal article Am J Hypertens · January 2004 Featured Publication BACKGROUND: Previous studies have suggested that African Americans have a greater left ventricular relative wall thickness than whites with similar levels of blood pressure (BP), whereas other investigators have documented an attenuated nocturnal decline i ... Full text Link to item Cite

Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment.

Journal article Psychosom Med · 2004 Featured Publication OBJECTIVE: The present paper reviews the evidence that depression is a risk factor for the development and progression of coronary artery disease (CAD). METHODS: MEDLINE searches and reviews of bibliographies were used to identify relevant articles. Articl ... Full text Link to item Cite

Interaction of Blood Pressure and Adult Age in Memory Search and Visual Search Performance

Journal article Aging Neuropsychology and Cognition · December 1, 2003 According to one model of the interaction between blood pressure and adult age, chronically elevated blood pressure accelerates age-related decline in fluid intelligence. To test this model, 48 unmedicated individuals with high blood pressure (HBP) and 48 ... Full text Cite

Depression as a risk factor for mortality after acute myocardial infarction.

Journal article Am J Cardiol · December 1, 2003 Featured Publication The ENRICHD clinical trial, which compared an intervention for depression and social isolation to usual care, failed to decrease the rate of mortality and recurrent acute myocardial infarction (AMI) in post-AMI patients. One explanation for this is that de ... Full text Link to item Cite

Psychiatric disorder and quality of life in patients awaiting lung transplantation.

Journal article Chest · November 2003 Featured Publication STUDY OBJECTIVE: To examine the relationship between psychiatric comorbidity and quality of life in patients awaiting lung transplantation. SETTING: Duke University Medical Center/Lung Transplantation Program. PARTICIPANTS: One hundred patients with end-st ... Full text Link to item Cite

Effects of exercise and weight loss on cardiac risk factors associated with syndrome X.

Journal article Arch Intern Med · September 8, 2003 Featured Publication BACKGROUND: Patients with high blood pressure (BP) often exhibit syndrome X, an aggregation of abnormalities in carbohydrate and lipoprotein metabolism associated with increased risk of coronary heart disease (CHD). The present study evaluated the effects ... Full text Link to item Cite

Depression as a risk factor for mortality after coronary artery bypass surgery.

Journal article Lancet · August 23, 2003 Featured Publication BACKGROUND: Studies that have shown clinical depression to be a risk factor for cardiac events after coronary artery bypass graft (CABG) surgery have had small sample sizes, short follow-up, and have not had adequate power to assess mortality. We sought to ... Full text Link to item Cite

Effects of exercise and weight loss on hypertension.

Journal article JAMA · August 20, 2003 Featured Publication Full text Link to item Cite

The Value of Stress-Management Interventions in Life-Threatening Medical Conditions

Journal article Current Directions in Psychological Science · August 1, 2003 Emotional stress has been associated with the development and progression of several chronic medical conditions. Recently, researchers have assessed the impact of stress-management interventions on patients' psychological functioning, quality of life, and ... Full text Cite

Cognitive and somatic symptoms of depression are associated with medical comorbidity in patients after acute myocardial infarction.

Journal article Am Heart J · July 2003 Featured Publication BACKGROUND: Depression is common in patients with acute myocardial infarction (AMI) and is associated with adverse health outcomes. However, the extent to which clinical depression is related to comorbid medical conditions is unknown. This study examined t ... Full text Link to item Cite

Depression and increased myocardial ischemic activity in patients with ischemic heart disease.

Journal article Am Heart J · July 2003 Featured Publication BACKGROUND: Depression is relatively common in patients with ischemic heart disease (IHD) and is associated with increased risk of mortality and morbidity. However, the mechanisms by which depression adversely affects clinical outcomes of patients with IHD ... Full text Link to item Cite

Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial.

Journal article JAMA · June 18, 2003 CONTEXT: Depression and low perceived social support (LPSS) after myocardial infarction (MI) are associated with higher morbidity and mortality, but little is known about whether this excess risk can be reduced through treatment. OBJECTIVE: To determine wh ... Full text Link to item Cite

Chronic exposure to nicotine does not prevent neurocognitive decline after cardiac surgery.

Journal article J Cardiothorac Vasc Anesth · June 2003 Featured Publication OBJECTIVE: To establish the association between smoking and cognitive decline in patients undergoing coronary artery bypass graft (CABG) surgery. DESIGN: Retrospective review. SETTING: Referral center for cardiothoracic surgery at a university hospital. PA ... Full text Link to item Cite

Depression and ischemic heart disease: overview of the evidence and treatment implications.

Journal article Curr Psychiatry Rep · May 2003 Featured Publication In this article, the authors review the evidence that depression is a risk factor for ischemic heart disease and examine the efficacy and safety of depression treatments in patients with ischemic heart disease. ... Full text Link to item Cite

Lower endotoxin immunity predicts increased cognitive dysfunction in elderly patients after cardiac surgery.

Journal article Stroke · February 2003 Featured Publication BACKGROUND AND PURPOSE: Although coronary artery bypass graft surgery (CABG) improves the quality of life and functional capacity for numerous patients, many also exhibit impairment in cognitive function immediately after surgery. Although the etiology of ... Full text Link to item Cite

Female gender is associated with impaired quality of life 1 year after coronary artery bypass surgery.

Journal article Psychosom Med · 2003 Featured Publication OBJECTIVE: To evaluate gender-related differences in quality of life (QOL) and cognitive function 1 year after coronary artery bypass surgery (CABG) after adjusting for known baseline differences. MATERIALS AND METHODS: Two hundred eighty patients (96 wome ... Full text Link to item Cite

Hostility, social support, and adrenergic receptor responsiveness among African-American and white men and women.

Journal article Psychosom Med · 2003 Featured Publication OBJECTIVE: We examined the relationship between beta-adrenergic receptor responsiveness and hostility and social support in African American and white men and women. METHODS: The participants were 149 men and women, aged 25 to 45 years with SBP < 160 and D ... Full text Link to item Cite

Exercise therapy for depression in middle-aged and older adults: predictors of early dropout and treatment failure.

Journal article Health Psychol · November 2002 Featured Publication Psychosocial factors predicting treatment dropout or failure to benefit from treatment were identified in a randomized trial of exercise therapy and pharmacotherapy for major depression. One hundred fifty-six men and women over age 50 diagnosed with major ... Link to item Cite

Effects of a telephone-based psychosocial intervention for patients awaiting lung transplantation.

Journal article Chest · October 2002 Featured Publication STUDY OBJECTIVES: To test the efficacy of a tailored telephone-based intervention consisting of supportive counseling and cognitive behavioral techniques for individuals awaiting lung transplantation on measures of quality of life and general well-being. M ... Full text Link to item Cite

Depression, heart rate variability, and acute myocardial infarction

Journal article Revista De Psiquiatria Clinica · September 14, 2002 Cite

Blunted nighttime blood pressure dipping in postmenopausal women in reply

Journal article American Journal of Hypertension · July 2002 Full text Cite

Reduction of left ventricular hypertrophy after exercise and weight loss in overweight patients with mild hypertension.

Journal article Arch Intern Med · June 24, 2002 Featured Publication BACKGROUND: Hypertrophy and concentric remodeling of the left ventricle are important manifestations of hypertension that are associated with increased morbidity and mortality. Although lifestyle interventions are efficacious in lowering blood pressure, ev ... Full text Link to item Cite

Biobehavioral approaches to the treatment of essential hypertension.

Journal article J Consult Clin Psychol · June 2002 Featured Publication Despite recent advances in the medical management of hypertension, chronically elevated blood pressure remains a major health problem in the United States, affecting almost 50 million Americans. It is widely recognized that lifestyle factors contribute to ... Link to item Cite

Changes in hemodynamics and left ventricular structure after menopause.

Journal article Am J Cardiol · April 1, 2002 Featured Publication To evaluate the cardiovascular changes associated with menopause, we studied hemodynamics at rest, ambulatory blood pressure, and left ventricular structure in a biracial cohort of pre- and postmenopausal women of similar age, race, weight, and blood press ... Full text Link to item Cite

Association of anxiety with reduced baroreflex cardiac control in patients after acute myocardial infarction.

Journal article Am Heart J · March 2002 Featured Publication BACKGROUND: Although depression has been associated with increased mortality in patients after acute myocardial infarction (AMI), little is known about the effects of depression on autonomic nervous system control of heart rate. This study evaluated whethe ... Full text Link to item Cite

Nighttime blood pressure dipping: the role of the sympathetic nervous system.

Journal article Am J Hypertens · February 2002 Featured Publication There is a marked diurnal variation in blood pressure (BP), with BP dipping to its lowest levels during nighttime sleep. A day-night dip in systolic BP (SBP) of <10% has been used to characterize individuals as nondippers, and is associated with an increas ... Full text Link to item Cite

The impact of postoperative atrial fibrillation on neurocognitive outcome after coronary artery bypass graft surgery.

Journal article Anesth Analg · February 2002 Featured Publication UNLABELLED: Neurocognitive decline is a continuing source of morbidity after cardiac surgery. Atrial fibrillation occurs often after cardiac surgery and has been linked to adverse neurologic events. We sought to determine whether postoperative atrial fibri ... Full text Link to item Cite

Usefulness of psychosocial treatment of mental stress-induced myocardial ischemia in men.

Journal article Am J Cardiol · January 15, 2002 Featured Publication This study examined the effects of exercise and stress management training on clinical outcomes and medical expenditures over a 5-year follow-up period in 94 male patients with established coronary artery disease (CAD) and evidence of ambulatory or mental ... Full text Link to item Cite

Exercise and the treatment of clinical depression in adults: recent findings and future directions.

Journal article Sports Med · 2002 Featured Publication This article critically reviews the evidence that exercise is effective in treating depression in adults. Depression is recognised as a mood state, clinical syndrome and psychiatric condition, and traditional methods for assessing depression (e.g. standard ... Full text Link to item Cite

Relationship of clinic, ambulatory, and laboratory stress blood pressure to left ventricular mass in overweight men and women with high blood pressure.

Journal article Psychosom Med · 2002 Featured Publication OBJECTIVE: This study was designed to evaluate the relationship between left ventricular (LV) mass and blood pressure (BP) recorded in the following contexts: in the clinic, using standard auscultatory procedures, during a typical day using ambulatory BP m ... Full text Link to item Cite

Report of the substudy assessing the impact of neurocognitive function on quality of life 5 years after cardiac surgery.

Journal article Stroke · December 1, 2001 Featured Publication BACKGROUND AND PURPOSE: The importance of perioperative cognitive decline has long been debated. We recently demonstrated a significant correlation between perioperative cognitive decline and long-term cognitive dysfunction. Despite this association, some ... Full text Link to item Cite

Prospective randomized trial of normothermic versus hypothermic cardiopulmonary bypass on cognitive function after coronary artery bypass graft surgery.

Journal article Anesthesiology · November 2001 Featured Publication BACKGROUND: Despite significant advances in cardiopulmonary bypass (CPB) technology, surgical techniques, and anesthetic management, central nervous system complications occur in a large percentage of patients undergoing surgery requiring CPB. Many centers ... Full text Link to item Cite

Depression, heart rate variability, and acute myocardial infarction.

Journal article Circulation · October 23, 2001 Featured Publication BACKGROUND: Clinical depression is associated with an increased risk for mortality in patients with a recent myocardial infarction (MI). Reduced heart rate variability (HRV) has been suggested as a possible explanation for this association. The purpose of ... Full text Link to item Cite

Effects of exercise and weight loss on blood pressure during daily life.

Journal article Med Sci Sports Exerc · October 2001 Featured Publication PURPOSE: The objective of this study was to investigate the effects of exercise training and weight loss on blood pressure (BP) associated with physical activity and emotional stress during daily life. METHODS: One hundred twelve participants with unmedica ... Full text Link to item Cite

Binge eating disorder and night eating syndrome: psychological and behavioral characteristics.

Journal article Int J Eat Disord · September 2001 Featured Publication OBJECTIVE: The present study was designed to examine the psychological and behavioral characteristics associated with both night eating syndrome (NES) and binge eating disorder (BED) in 42 males and 41 females who were enrolled in a university-based weight ... Full text Link to item Cite

Neurocognitive function after coronary-artery bypass surgery. Reply

Journal article NEW ENGLAND JOURNAL OF MEDICINE · August 16, 2001 Link to item Cite

Blunted nighttime blood pressure dipping in postmenopausal women.

Journal article Am J Hypertens · August 2001 Featured Publication Blunting of the normal drop in blood pressure (BP) from day to night is emerging as a strong prognostic indicator of cardiovascular morbidity and mortality. This study evaluated the effects of natural menopause on BP dipping in African American and white w ... Full text Link to item Cite

Linkages between facial expressions of anger and transient myocardial ischemia in men with coronary artery disease.

Journal article Emotion · June 2001 Featured Publication The authors examined whether facial expressions of emotion would predict changes in heart function. One hundred fifteen male patients with coronary artery disease underwent the Type A Structured Interview, during which time measures of transient myocardial ... Full text Link to item Cite

Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery.

Journal article N Engl J Med · February 8, 2001 Featured Publication BACKGROUND: Cognitive decline complicates early recovery after coronary-artery bypass grafting (CABG) and may be evident in as many as three quarters of patients at the time of discharge from the hospital and a third of patients after six months. We sought ... Full text Link to item Cite

Effects of exercise training on cognitive functioning among depressed older men and women

Journal article Journal of Aging and Physical Activity · January 1, 2001 The effects of a structured exercise program on the cognitive functioning of 84 clinically depressed middle-aged and older adults (mean age = 57 years) were examined. Participants were randomized to either 4 months of aerobic exercise (n = 42) or antidepre ... Full text Cite

Depression and vascular function in older adults

Journal article North Carolina Medical Journal · 2001 Cite

Blunted nighttime blood pressure

Journal article American Journal of Hypertension · 2001 Cite

Enhancing Recovery in Coronary Heart Disease (ENRICHD) study intervention: rationale and design.

Journal article Psychosom Med · 2001 OBJECTIVE: Depression and low social support are risk factors for medical morbidity and mortality after acute MI. The ENRICHD study is a multicenter, randomized, controlled clinical trial of a cognitive-behavioral treatment for depression and low social su ... Link to item Cite

Hemodynamic mechanisms of mental stress-induced ischemia

Journal article PSYCHOSOMATIC MEDICINE · January 1, 2001 Link to item Cite

Communication to the editor: Response to Taggart, Browne & Halligan

Journal article New England Journal of Medicine · 2001 Cite

Religious coping, ethnicity, and ambulatory blood pressure.

Journal article Psychosom Med · 2001 Featured Publication OBJECTIVE: To investigate the relationship between religious coping, ethnicity, and ambulatory blood pressure (ABP) measured during daily life. METHODS: A 24-hour ABP was obtained from 155 men and women (78 African American and 77 white) on a typical workd ... Full text Link to item Cite

Psychosocial characteristics after acute myocardial infarction: the ENRICHD pilot study. Enhancing Recovery in Coronary Heart Disease.

Journal article J Cardiopulm Rehabil · 2001 Featured Publication PURPOSE: Psychosocial factors, such as emotional distress and social isolation, have been increasingly recognized as important risk factors for patients' recovery from acute myocardial infarction (AMI). This study examined age, gender, and ethnic differenc ... Full text Link to item Cite

Temperature during coronary artery bypass surgery affects quality of life.

Journal article Ann Thorac Surg · January 2001 Featured Publication BACKGROUND: The objective of this study was to examine the effects of temperature on a variety of indices of psychologic adjustment and quality of life. METHODS: A total of 209 patients randomly received normothermic (warm) or hypothermic (cold) conditions ... Full text Link to item Cite

Effects of exercise and weight loss on blood pressure during daily life

Journal article PSYCHOSOMATIC MEDICINE · January 1, 2001 Link to item Cite

Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure.

Journal article Hypertension · August 2000 Featured Publication The purpose of this study was to determine the effects of exercise and weight loss on cardiovascular responses during mental stress in mildly to moderately overweight patients with elevated blood pressure. Ninety-nine men and women with high normal or unme ... Full text Link to item Cite

Exercise and weight loss reduce blood pressure in men and women with mild hypertension: effects on cardiovascular, metabolic, and hemodynamic functioning.

Journal article Arch Intern Med · July 10, 2000 Featured Publication BACKGROUND: Lifestyle modifications have been recommended as the initial treatment strategy for lowering high blood pressure (BP). However, evidence for the efficacy of exercise and weight loss in the management of high BP remains controversial. METHODS: O ... Full text Link to item Cite

Nonoperative management of hepatic, splenic, and renal injuries in adults with multiple injuries - Discussion

Journal article JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE · July 2000 Link to item Cite

Emotional responsivity during daily life: relationship to psychosocial functioning and ambulatory blood pressure.

Journal article Int J Psychophysiol · April 2000 Featured Publication Emotional responsivity refers to acute changes in affective states. This study examined the relationship of emotional responsivity during daily life with ambulatory blood pressure (ABP) and psychosocial functioning. Subjects were 162 employed men and women ... Full text Link to item Cite

Enhancing recovery in coronary heart disease patients (ENRICHD): study design and methods. The ENRICHD investigators.

Journal article Am Heart J · January 2000 Psychosocial factors, particularly depression and lack of social support, are important predictors of morbidity and mortality in patients with coronary heart disease. This article describes the design and methods of the Enhancing Recovery in Coronary Heart ... Full text Link to item Cite

Neurocognitive dysfunction and quality of life after cardiac surgery

Journal article The Annals of Thoracic Surgery · 2000 Cite

Ambulatory blood pressure and marital distress in employed women.

Journal article Behav Med · 2000 Featured Publication In this investigation, the relationship between marital distress and blood pressure during daily life in a sample of married employed women was examined. It was hypothesized that greater marital distress would be associated with elevated blood pressure in ... Full text Link to item Cite

Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months.

Journal article Psychosom Med · 2000 Featured Publication OBJECTIVE: The purpose of this study was to assess the status of 156 adult volunteers with major depressive disorder (MDD) 6 months after completion of a study in which they were randomly assigned to a 4-month course of aerobic exercise, sertraline therapy ... Full text Link to item Cite

ANXIETY, DEPRESSION, AND HEART RATE VARIABILITY

Journal article Psychosomatic Medicine · January 2000 Full text Cite

Religious coping, ethnicity, and ambulatory blood pressure

Journal article PSYCHOSOMATIC MEDICINE · January 1, 2000 Link to item Cite

Cognitive decline after major noncardiac operations: a preliminary prospective study.

Journal article Ann Thorac Surg · November 1999 Featured Publication BACKGROUND: Cardiac operations frequently are complicated by postoperative cognitive decline. Less common and less studied is postoperative cognitive decline after noncardiac surgery, so we determined its incidence, severity, and possible predictors. METHO ... Full text Link to item Cite

Effects of exercise training on older patients with major depression.

Journal article Arch Intern Med · October 25, 1999 Featured Publication BACKGROUND: Previous observational and interventional studies have suggested that regular physical exercise may be associated with reduced symptoms of depression. However, the extent to which exercise training may reduce depressive symptoms in older patien ... Full text Link to item Cite

Worried to death?

Journal article Circulation · September 14, 1999 Featured Publication Link to item Cite

Worried to death? [4] (multiple letters)

Journal article Circulation · September 14, 1999 Cite

Emotional responsivity and transient myocardial ischemia.

Journal article J Consult Clin Psychol · August 1999 Featured Publication This study examined the relationship between "emotional responsivity" (i.e., individuals who exhibit relatively large variations of self-reported tension levels) and myocardial ischemia. One hundred thirty-six patients with coronary artery disease underwen ... Full text Link to item Cite

Perception of cognitive function in older adults following coronary artery bypass surgery.

Journal article Health Psychol · May 1999 Featured Publication This study examined the effects of coronary artery bypass grafting (CABG) on objective and subjective measures of neurocognitive functioning. Participants were 170 older patients (127 men and 43 women; mean age = 61 years) undergoing CABG. Measures of neur ... Full text Link to item Cite

Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy.

Journal article Circulation · April 27, 1999 Featured Publication Recent studies provide clear and convincing evidence that psychosocial factors contribute significantly to the pathogenesis and expression of coronary artery disease (CAD). This evidence is composed largely of data relating CAD risk to 5 specific psychosoc ... Full text Link to item Cite

The association between physical activity and depression in older depressed adults

Journal article Journal of Aging and Physical Activity · January 1, 1999 Previous studies of younger, healthy individuals have demonstrated an inverse relationship between physical activity and depression. The present study addressed the relation between self-reported physical activity and symptoms of depression in 146 men and ... Full text Cite

Mental stress and coronary disease. The Smart-Heart Study.

Journal article N C Med J · 1999 Featured Publication Link to item Cite

Anxiety reduces baroreflex cardiac control in older adults with major depression.

Journal article Psychosom Med · 1999 Featured Publication OBJECTIVE: Although depression and anxiety predict risk of cardiac mortality, the contributions of depression and anxiety to vagal cardiac control have not been systematically evaluated. The goal of this study was to examine the relationship between state ... Full text Link to item Cite

Predicting peak oxygen uptake among older patients with chronic illness.

Journal article J Cardiopulm Rehabil · 1999 Featured Publication PURPOSE: To compare three equations developed to predict VO2 among patients diagnosed with one of two chronic diseases: essential hypertension (HTN), and fibromyalgia (FM). The equations included the American College of Sports Medicine (ACSM) equation, the ... Full text Link to item Cite

Endothelial function and hemodynamic responses during mental stress.

Journal article Psychosom Med · 1999 Featured Publication OBJECTIVE: The hemodynamic basis of blood pressure responses during psychological stress shows striking individual differences that share an interesting similarity with risk for cardiovascular disease. Factors accounting for these individual differences ar ... Full text Link to item Cite

EXERCISE TRAINING AND MAJOR DEPRESSION

Journal article Psychosomatic Medicine · 1999 Full text Cite

Facial expression and the affective component of cynical hostility in male coronary heart disease patients.

Journal article Health Psychol · July 1998 Featured Publication This study describes the affective component of hostility as measured by the Cook-Medley Hostility Scale (Ho; W. Cook & D. Medley, 1954) by examining the relationship between facial expressions of emotion and Ho scores in 116 male coronary heart disease pa ... Full text Link to item Cite

THE QUANTITATIVE ELECTROENCEPHALOGRAM (QEEG)

Journal article Anesthesia & Analgesia · April 1998 Full text Cite

Psychosocial influences on blood pressure during daily life.

Journal article Int J Psychophysiol · March 1998 Featured Publication Ambulatory blood pressure (ABP) monitoring allows frequent non-invasive blood pressure (BP) recordings in a variety of settings. Emerging evidence suggests that ABP is a better predictor of cardiovascular morbidity than clinic BP. Ambulatory blood pressure ... Full text Link to item Cite

The reasonable woman standard: a meta-analytic review of gender differences in perceptions of sexual harassment.

Journal article Law Hum Behav · February 1998 Featured Publication Courts and legislatures have begun to develop the "reasonable woman standard" (RWS) as a criterion for deciding sexual harassment trials. This standard rests on assumptions of a "wide divergence" between the perceptions of men and women when viewing social ... Full text Link to item Cite

Muscarinic inhibition of substance P induced ion secretion in piglet jejunum.

Journal article Can J Physiol Pharmacol · February 1998 Featured Publication We examined the effects of the muscarinic agonist carbachol on ion secretion induced by substance P (SP) in piglet jejunal tissues mounted in Ussing chambers. Tetrodotoxin was present in all solutions to inhibit neural activity. Carbachol added 10 min prio ... Link to item Cite

High anxiety and white coat hypertension.

Journal article JAMA · January 21, 1998 Featured Publication Full text Link to item Cite

Interaction of hypertension and age in visual selective attention performance.

Journal article Health Psychol · January 1998 Featured Publication Previous research suggests that some aspects of cognitive performance decline as a joint function of age and hypertension. In this experiment, 51 unmedicated individuals with mild essential hypertension and 48 normotensive individuals, 18-78 years of age, ... Full text Link to item Cite

Blood pressure reactivity and marital distress in employed women.

Journal article Psychosom Med · 1998 Featured Publication OBJECTIVE: The impact of marital distress on cardiovascular responses to an "ecologically valid" laboratory stressor (a marital conflict recall task) was examined in maritally distressed and non-distressed women. It was hypothesized that the presence of hi ... Full text Link to item Cite

Exercise training as an alternative treatment for depression among older adults.

Journal article Altern Ther Health Med · January 1998 Featured Publication This article reviews the current literature related to exercise treatment and depression among older adults. Results from investigational studies support the antidepressive effects of exercise programs. Aerobic exercise is more effective than placebo or no ... Link to item Cite

Effect of satisfaction with social support on blood pressure in normotensive and borderline hypertensive men and women.

Journal article Int J Behav Med · 1998 Featured Publication The relation between blood pressure (BP) and two aspects of social support, perceived satisfaction and structural social support network characteristics, were examined in adults classified as having normal BP or borderline hypertension. Causal BPs were tak ... Full text Link to item Cite

Cognitive function 5 years after randomization to coronary angioplasty or coronary artery bypass graft surgery.

Journal article Circulation · November 4, 1997 Featured Publication BACKGROUND: Coronary bypass surgery often leads to short-term cognitive dysfunction, whereas coronary angioplasty does not. Perioperative cognitive dysfunction usually resolves, although a subgroup of surgical patients may continue to exhibit long-term cog ... Link to item Cite

Stress management and exercise training in cardiac patients with myocardial ischemia. Effects on prognosis and evaluation of mechanisms.

Journal article Arch Intern Med · October 27, 1997 Featured Publication BACKGROUND: Previous studies have demonstrated that myocardial ischemia can be elicited by mental stress in the laboratory and during daily life and that ischemia induced by mental stress is associated with an increased risk for future cardiac events in pa ... Link to item Cite

Defining dysfunction: group means versus incidence analysis--a statement of consensus.

Journal article Ann Thorac Surg · September 1997 Featured Publication Full text Link to item Cite

Stability over time of circadian rhythm of variability of heart rate in patients with stable coronary artery disease.

Journal article Am Heart J · September 1997 Featured Publication Reproducibility of circadian rhythm of variability in heart rate was studied in 40 patients with stable coronary artery disease who underwent 48-hour ambulatory electrocardiographic recordings at baseline (time 1) and after 4 months (time 2). The standard ... Full text Link to item Cite

Psychosocial correlates of job strain in a sample of working women.

Journal article Arch Gen Psychiatry · June 1997 Featured Publication BACKGROUND: This study identifies potential mediators of job strain effects on health by determining whether psychosocial factors known to predict an increased risk of cardiovascular disease and all-cause mortality are higher among women who report high le ... Full text Link to item Cite

Effects of mental stress on myocardial ischemia during daily life.

Journal article JAMA · May 21, 1997 Featured Publication OBJECTIVE: To determine the relative risk of myocardial ischemia triggered by specific emotions during daily life. DESIGN AND SETTING: Relative risk was calculated by the recently developed case-crossover method, in which the frequency of a presumed trigge ... Link to item Cite

Personality factors differentially predict exercise behavior in men and women.

Journal article Womens Health · 1997 Featured Publication Personality assessed with the Minnesota Multiphasic Personality Inventory (MMPI) in college was used to predict exercise behavior measured at midlife in 3,630 men and 796 women enrolled in the University of North Carolina Alumni Heart Study. Logistic regre ... Link to item Cite

Psychosocial factors and coronary disease. A national multicenter clinical trial (ENRICHD) with a North Carolina focus.

Journal article N C Med J · 1997 Featured Publication In addition to traditional risk factors (cigarette smoking, high blood pressure, and elevated cholesterol) psychosocial factors (depression, social isolation, and low socioeconomic status) have an adverse impact on prognosis of patients with CAD. Several s ... Link to item Cite

Relation of mood ratings and neurohormonal responses during daily life in employed women.

Journal article Int J Behav Med · 1997 Featured Publication Diurnal variations in urinary norepinephrine, epinephrine, cortisol, and self-reported mood states were examined in 101 employed women. Urine was collected on 2 consecutive workdays at 3 time periods: (1) overnight, (2) daytime, and (3) evening. Self-repor ... Full text Link to item Cite

Stress in employed women: impact of marital status and children at home on neurohormone output and home strain.

Journal article Psychosom Med · 1997 Featured Publication OBJECTIVE: To evaluate the biological and psychological effects of role overload, we examined the effects of marital (or partnership) status and parental status (defined as having children at home) on daily excretion of urinary catecholamines and cortisol ... Full text Link to item Cite

Cardiac rehabilitation as secondary prevention: Quick reference guide for clinicians

Journal article Journal of Pharmaceutical Care in Pain and Symptom Control · December 1, 1996 This Quick Reference Guide for Clinicians highlights the conclusions and recommendations from Cardiac Rehabilitation, Clinical Practice Guideline No. 17, which was formulated by a panel representing the major health care disciplines involved in cardiac reh ... Cite

Pain in arthritis and musculoskeletal disorders: the role of coping skills training and exercise interventions.

Journal article J Orthop Sports Phys Ther · October 1996 Featured Publication There is growing recognition of the limitations of conventional, biomedical approaches to the management of pain in individuals having arthritis and musculoskeletal disorders. This article provides an overview of newly developed biopsychosocial approaches ... Full text Link to item Cite

Depression and long-term mortality risk in patients with coronary artery disease.

Journal article Am J Cardiol · September 15, 1996 Featured Publication Previous research has established that patients with coronary artery disease (CAD) have an increased risk of death if they are depressed at the time of hospitalization. Follow-up periods have been short in these studies; therefore, the present investigatio ... Full text Link to item Cite

Is the target income hypothesis an economic heresy?

Journal article Med Care Res Rev · September 1996 Featured Publication Full text Link to item Cite

Mental stress--induced myocardial ischemia and cardiac events.

Journal article JAMA · June 5, 1996 Featured Publication OBJECTIVE: To assess the clinical significance of mental stress-induced myocardial ischemia in patients with coronary artery disease (CAD). DESIGN AND SETTING: Cohort study in outpatients in a tertiary care teaching hospital assessed at baseline and follow ... Full text Link to item Cite

Defining neuropsychological dysfunction after coronary artery bypass grafting.

Journal article Ann Thorac Surg · May 1996 Featured Publication BACKGROUND: Despite the large body of literature documenting the presence of cognitive decline after coronary artery bypass grafting, there is little consensus as to the frequency and extent of cognitive impairment. One potential reason for this lack of ag ... Full text Link to item Cite

Exercise therapy for the prevention and treatment of depression

Journal article Journal of Practical Psychiatry and Behavioral Health · January 1, 1996 The authors review evidence suggesting that regular aerobic exercise - walking, jogging, swimming, or biking - reduces depression in healthy adults and in patients with major depression. Several potential mechanisms for the antidepressant effects of exerci ... Full text Cite

New version of brief depression scale.

Journal article J Am Geriatr Soc · December 1995 Full text Link to item Cite

Mental stress-induced ischemia in the laboratory and ambulatory ischemia during daily life. Association and hemodynamic features.

Journal article Circulation · October 15, 1995 Featured Publication BACKGROUND: The purpose of this study was to determine the correspondence of mental stress-induced ischemia in the laboratory with ambulatory ischemia and to assess the relationship between hemodynamic responses to mental stress and the occurrence of ische ... Full text Link to item Cite

Cardiac rehabilitation as secondary prevention. Agency for Health Care Policy and Research and National Heart, Lung, and Blood Institute.

Journal article Clin Pract Guidel Quick Ref Guide Clin · October 1995 Featured Publication This Quick Reference Guide for Clinicians highlights the conclusions and recommendations from Cardiac Rehabilitation, Clinical Practice Guideline No. 17, which was formulated by a panel representing the major health care disciplines involved in cardiac reh ... Link to item Cite

Relative importance of electrode placement over number of channels in transient myocardial ischemia detection by Holter monitoring.

Journal article Am J Cardiol · August 15, 1995 Featured Publication To compare the efficacy of 3-channel ambulatory electrocardiographic monitoring (Holter monitoring) with 2-channel Holter monitoring in the detection of transient myocardial ischemia (TMI), channels CM2, CM5, and modified II were studied. Sixty patients wi ... Full text Link to item Cite

Differential age effects of mean arterial pressure and rewarming on cognitive dysfunction after cardiac surgery.

Journal article Anesth Analg · August 1995 Featured Publication Central nervous system dysfunction is a common consequence of otherwise uncomplicated cardiac surgery. Many mechanisms have been postulated for the cognitive dysfunction that is part of these neurologic sequelae. The purpose of our investigation was to eva ... Full text Link to item Cite

Ethnic differences in hemodynamic responses to stress in hypertensive men and women.

Journal article Am J Hypertens · June 1995 Featured Publication Hemodynamic response patterns to three laboratory stressors were compared in 63 mildly hypertensive black and white men and women. Ethnic groups were matched for age, body mass index, and casual blood pressures. Stressors included a mental arithmetic task, ... Full text Link to item Cite

Distinguishing between early and late responders to symptoms of acute myocardial infarction.

Journal article Am J Cardiol · May 15, 1995 Featured Publication The present study identified factors that distinguish early responders (i.e., requested medical assistance < 60 minutes after the onset of acute myocardial infarction [AMI] symptoms) from late responders (i.e., request made > or = 60 minutes after symptom ... Full text Link to item Cite

Predictors of cognitive decline after cardiac operation.

Journal article Ann Thorac Surg · May 1995 Featured Publication Despite major advances in cardiopulmonary bypass technology, surgical techniques, and anesthesia management, central nervous system complications remain a common problem after cardiopulmonary bypass. The etiology of neuropsychologic dysfunction after cardi ... Full text Link to item Cite

Methodological issues in the assessment of neuropsychologic function after cardiac surgery.

Journal article Ann Thorac Surg · May 1995 Featured Publication This report reviews critical issues facing investigators interested in neuropsychologic sequelae after cardiac operations: (1) experimental design; (2) selective attrition; (3) selection of instruments; (4) moderating factors; (5) definitions of cognitive ... Full text Link to item Cite

Depression in male and female patients undergoing cardiac surgery.

Journal article Br J Clin Psychol · February 1995 Featured Publication The present longitudinal study was designed to determine the prevalence of depression in male and female patients undergoing cardiac surgery, and to examine what factors are associated with depression before and after surgery. One day prior to surgery (T1) ... Full text Link to item Cite

Contribution of job strain, job status and marital status to laboratory and ambulatory blood pressure in patients with mild hypertension.

Journal article J Psychosom Res · February 1995 Featured Publication The effects of job strain, occupational status, and marital status on blood pressure were evaluated in 99 men and women with mild hypertension. Blood pressure was measured during daily life at home and at work over 15 h of ambulatory blood pressure monitor ... Full text Link to item Cite

Do exercise and weight loss reduce blood pressure in patients with mild hypertension?

Journal article N C Med J · February 1995 Featured Publication We conclude from our review that exercise and weight loss offer some promise as non-pharmacologic treatments for hypertension. Unfortunately, most available studies are methodologically unsound, and the mechanisms by which exercise lowers blood pressure ar ... Link to item Cite

Ethnic differences in hemodynamic responses to stress in hypertensive men and women

Journal article American Journal of Hypertension · 1995 Cite

The Mini mental state exam as a predictor of neuropsychological functioning after cardiac surgery

Journal article International Journal of Psychiatry in Medicine: Biopsychosocial Aspects of Patient Care · 1995 Cite

Cardiac rehabilitation

Journal article Clinical Practice Guideline · 1995 Cite

Family history of hypertension influences neurobehavioral function in hypertensive patients.

Journal article Psychosom Med · 1995 Featured Publication This study examined the influence of family history of hypertension on neurobehavioral performance. Sixty-two hypertensive men and women who reported a family history of hypertension (+FH) were compared with 28 hypertensive individuals without a family his ... Full text Link to item Cite

The Mini Mental State Exam as a predictor of neuropsychological functioning after cardiac surgery.

Journal article Int J Psychiatry Med · 1995 Featured Publication OBJECTIVE: The present longitudinal study was designed to: 1) determine the ability of the Mini Mental State Exam (MMSE) to predict neuropsychologic impairment based on neuropsychologic testing five to seven days and six weeks after cardiac surgery; and 2) ... Full text Link to item Cite

Association of physical fitness and transient myocardial ischemia in patients with coronary artery disease.

Journal article J Cardiopulm Rehabil · 1995 Featured Publication PURPOSE: To examine the relationship between physical fitness and transient myocardial ischemia (TMI) in the laboratory and during daily life, in a sample of coronary patients with a recent positive exercise test. METHODS: 47 patients with coronary disease ... Full text Link to item Cite

Jugular bulb saturation and cognitive dysfunction after cardiopulmonary bypass.

Journal article Ann Thorac Surg · December 1994 Featured Publication Inadequate cerebral oxygenation during cardiopulmonary bypass may lead to postoperative cognitive dysfunction in patients undergoing cardiac operations. A psychological test battery was administered to 255 patients before cardiac operation and just before ... Full text Link to item Cite

Effect of aging on cerebral autoregulation during cardiopulmonary bypass. Association with postoperative cognitive dysfunction.

Journal article Circulation · November 1994 Featured Publication BACKGROUND: Age is a predictor of cognitive dysfunction after cardiac surgery, but the mechanism is unknown. The purpose of our study was to determine whether age-related decrements in cognition are associated with cerebral blood flow (CBF) autoregulation ... Link to item Cite

Effect of aging on cerebral autoregulation during cardiopulmonary bypass: Association with postoperative cognitive dysfunction

Journal article Circulation · November 1, 1994 Background: Age is a predictor of cognitive dysfunction after cardiac surgery, but the mechanism is unknown. The purpose of our study was to determine whether age-related decrements in cognition are associated with cerebral blood flow (CBF) autoregulation ... Cite

Cardiovascular reactivity to mental stress in hypertensive patients receiving atenolol vs enalapril

Journal article Journal of Cardiopulmonary Rehabilitation · January 1, 1994 Background. This study compared the effects of the cardioselective beta- blocker, atenolol (AT), and the angiotensin-converting enzyme inhibitor, enalapril (EN), on psychophysiologic reactivity to mental stress among hypertensive patients inadequately cont ... Full text Cite

Prognostic significance of silent myocardial ischemia

Journal article Annals of Behavioral Medicine · January 1, 1994 Transient myocardial ischemia (TMI), a condition in which blood flow to the heart is temporarily restricted, has been recognized as an important measure of cardiovascular disease activity. Episodes of TMI are associated with an increased risk of adverse ca ... Cite

Quality of life and recovery after cardiac surgery.

Journal article Psychosom Med · 1994 Featured Publication Full text Link to item Cite

Serum lipids, neuroendocrine, and cardiovascular responses to stress in men and women with mild hypertension.

Journal article Behav Med · 1994 Featured Publication In this study, we examined the relation between serum lipid levels, gender, and cardiovascular and neuroendocrine stress reactivity in patients with mild hypertension. Ninety-nine individuals (62 men, 37 women) with mild hypertension performed four mental ... Full text Link to item Cite

Relation of cardiovascular responses to mental stress and cardiac vagal activity in coronary artery disease.

Journal article Am J Cardiol · September 1, 1993 Featured Publication Forty-six patients with documented coronary artery disease were studied to examine the relation of cardiovascular reactivity to mental stress and cardiac vagal activity. Cardiac vagal activity was measured by means of frequency-domain analysis of heart rat ... Full text Link to item Cite

Effects of aerobic exercise on cognitive and psychosocial functioning in patients with mild hypertension.

Journal article Health Psychol · July 1993 Featured Publication The effects of 16 weeks of physical exercise training on the psychological functioning of 90 patients with mild hypertension were examined. At baseline and after 16 weeks of training, patients completed a psychometric test battery that included objective m ... Full text Link to item Cite

Psychobehavioral treatment in cardiac rehabilitation.

Journal article Cardiol Clin · May 1993 Featured Publication This article reviews the empirical evidence for the use of behavioral and psychological therapies in the rehabilitation of patients with coronary disease. Exercise training, Type A modification, psychological counseling, smoking cessation, and dietary modi ... Link to item Cite

THE EFFICACY OF EXERCISE IN THE MANAGEMENT OF HYPERTENSION

Journal article HOMEOSTASIS IN HEALTH AND DISEASE · 1993 Link to item Cite

The effects of aerobic exercise on premenstrual symptoms in middle-aged women: a preliminary study.

Journal article J Psychosom Res · 1993 Featured Publication The effects of aerobic exercise and strength training on premenstrual symptoms were evaluated in 23 healthy premenopausal women. Premenstrual symptoms were assessed at baseline and following 3 months of exercise participation. Women who engaged in aerobic ... Full text Link to item Cite

Hypertension affects neurobehavioral functioning.

Journal article Psychosom Med · 1993 Featured Publication This study compared the neurobehavioral performance of hypertensive and normotensive men and women using neuropsychological, information-processing, and psychometric assessments. One hundred subjects, including 68 hypertensive and 32 normotensive individua ... Full text Link to item Cite

Serum lipids, neuroendocrine and cardiovascular responses to stress in healthy Type A men.

Journal article Biol Psychol · October 1992 Featured Publication This study examined the relationship between serum lipid activity in healthy Type A men and cardiovascular and neuroendocrine responses to a behavioral stressor, mental arithmetic. Assessment of blood lipids included measures of total cholesterol (TC), low ... Full text Link to item Cite

Obsessive and compulsive traits in athletes.

Journal article Sports Med · October 1992 Featured Publication Full text Link to item Cite

Exercise adherence or maintenance among older adults: 1-year follow-up study.

Journal article Psychol Aging · September 1992 Featured Publication Follow-up evaluation was conducted of 101 older men and women (mean age = 67 +/- 5 years) who had participated in a randomized study of physiological and psychological effects of aerobic exercise. Eighty-five subjects completed the follow-up evaluation, an ... Full text Link to item Cite

CORRECTION

Journal article JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION · June 17, 1992 Link to item Cite

Warming during cardiopulmonary bypass is associated with jugular bulb desaturation.

Journal article Ann Thorac Surg · May 1992 Featured Publication The objective of this study was to characterize cerebral venous effluent during normothermic nonpulsatile cardiopulmonary bypass. Thirty-one (23%) of 133 patients met desaturation criteria (defined as jugular bulb venous oxygen saturation less than or equa ... Full text Link to item Cite

In Reply

Journal article JAMA the Journal of the American Medical Association · April 1, 1992 Full text Cite

Letter to the editor

Journal article Journal of the American Medical Association · 1992 Cite

Failure of exercise to reduce blood pressure

Journal article Annals of Internal Medicine · January 1, 1992 Cite

Failure of exercise to reduce hypertension [2]

Journal article Journal of the American Medical Association · 1992 Full text Cite

Failure of exercise to reduce blood pressure

Journal article Annals of Internal Medicine · January 1, 1992 Cite

Long-term effects of exercise on psychological functioning in older men and women.

Journal article J Gerontol · November 1991 Featured Publication The purpose of this study was to determine the psychological, behavioral, and cognitive changes associated with up to 14 months of aerobic exercise training. For the first 4 months of the study, 101 older (greater than 60 years) men and women were randomly ... Full text Link to item Cite

Effects of exercise training on bone density in older men and women.

Journal article J Am Geriatr Soc · November 1991 Featured Publication OBJECTIVES: To determine the effects of up to 14 months of aerobic exercise on measures of bone density in older adults. DESIGN: Randomized controlled trial with subjects assigned to either an aerobic exercise condition, non-aerobic yoga, or a wait list no ... Full text Link to item Cite

Failure of exercise to reduce blood pressure in patients with mild hypertension. Results of a randomized controlled trial.

Journal article JAMA · October 16, 1991 Featured Publication OBJECTIVE: --To assess the effects of physical exercise training on blood pressure in patients with mild hypertension. DESIGN: --Randomized controlled trial. SETTING: --Hospital-based cardiac rehabilitation program. PATIENTS: --Ninety-nine men and women wi ... Link to item Cite

Effects of exercise training on cardiorespiratory function in men and women older than 60 years of age.

Journal article Am J Cardiol · March 15, 1991 Featured Publication This study reports the physiologic effects of up to 14 months of aerobic exercise in 101 older (greater than 60 years) men and women. After an extensive baseline physiologic assessment (Time 1), in which aerobic capacity and blood lipids were measured, sub ... Full text Link to item Cite

PERSONALITY PREDICTION OF EXERCISE IN THE UNC ALUMNI HEART-STUDY

Journal article PSYCHOSOMATIC MEDICINE · March 1, 1991 Link to item Cite

The role of exercise in the prevention and treatment of hypertension

Journal article Annals of Behavioral Medicine · January 1, 1991 Cite

Ambulatory blood pressure responses during daily life in high and low hostile patients with a recent myocardial infarction

Journal article Journal of Cardiopulmonary Rehabilitation · January 1, 1991 This study examined cardiovascular (CV) responses during daily activities among patients with myocardial infarction (MI) with high and low scores on the Cook-Medley hostility (Ho) questionnaire. Ambulatory recordings of heart rate (HR) and blood pressure ( ... Full text Cite

Effects of physical exercise on psychological and cognitive functioning of older adults

Journal article Annals of Behavioral Medicine · January 1, 1991 Cite

Stress reactivity and exercise training in premenopausal and postmenopausal women.

Journal article Health Psychol · 1991 Featured Publication Examined the influence of ovarian function on psychophysiological stress responses and determined if aerobic exercise reduced stress reactivity. Fifty premenopausal and postmenopausal women initially were subjected to a public speaking task and an ice-on-t ... Full text Link to item Cite

A preliminary study of the effects of cardiac procedures on cognitive performance.

Journal article Int J Psychosom · 1991 Featured Publication The effects of three commonly performed cardiac procedures on cognitive performance were evaluated in patients undergoing coronary artery bypass graft (CABG) surgery (N = 20), percutaneous transluminal coronary angioplasty (PTCA) procedure (N = 8), or card ... Link to item Cite

Effects of exercise training on cardiovascular function and plasma lipid, lipoprotein, and apolipoprotein concentrations in premenopausal and postmenopausal women.

Journal article Arterioscler Thromb · 1991 Featured Publication This study examined the effects of aerobic exercise on lipid levels in premenopausal and postmenopausal women. Fifty healthy middle-aged women (mean age, 50 years) were randomly assigned to 12 weeks of either aerobic exercise (walking and jogging) or nonae ... Full text Link to item Cite

Temporal stability of the hemodynamics of cardiovascular reactivity.

Journal article Int J Psychophysiol · November 1990 Featured Publication Cardiovascular responses to a competitive reaction-time task were monitored in 13 male subjects tested twice, 3 months apart. The temporal stability of blood pressure responses was in line with previous reports. However, in this study impedance cardiograph ... Full text Link to item Cite

Quality of life among hypertensive patients with a diuretic background who are taking atenolol and enalapril.

Journal article Clin Pharmacol Ther · October 1990 Featured Publication The cardioselective beta-blocker atenolol and the angiotensin-converting enzyme inhibitor enalapril were compared for efficacy, safety, and quality-of-life factors in 30 patients with hypertension whose hypertension was inadequately controlled with diureti ... Full text Link to item Cite

Physiological, psychological, and behavioral factors and white coat hypertension.

Journal article Hypertension · August 1990 Featured Publication Patients with hypertension in the clinic but not during daily activities ("white coat" hypertension) may be at lower risk of hypertensive morbidity and mortality than patients with hypertension in both settings ("persistent" hypertension). We hypothesized ... Full text Link to item Cite

Perceived change among participants in an exercise program for older adults.

Journal article Gerontologist · August 1990 Featured Publication Data regarding perceived change were collected as part of a study of the effects of aerobic exercise training on psychological, cognitive, and physiological functioning among 101 healthy older adults. Subjects were assigned randomly to an aerobic exercise ... Full text Link to item Cite

Coronary artery bypass grafting and cognitive function: A review

Journal article Journal of Cardiopulmonary Rehabilitation · January 1, 1990 Coronary artery bypass grafting (CABG) is a well-established and common surgical procedure for the treatment of coronary artery disease (CAD). Although CABG is associated with increased survival, especially in patients with left main or 3-vessel disease, t ... Full text Cite

Serum lipid levels and ambulatory blood pressure

Journal article Journal of Ambulatory Monitoring · 1990 Cite

Physiologic, psychologic, and behavioral factors

Journal article Hypertension · 1990 Cite

Depression and the assessment of Type A behavior in a clinical population

Journal article Psychological Assessment: A Journal of Consulting and Clinical Psychology · 1990 Cite

Aerobic exercise reduces levels of cardiovascular and sympathoadrenal responses to mental stress in subjects without prior evidence of myocardial ischemia.

Journal article Am J Cardiol · January 1, 1990 Featured Publication Thirty-seven healthy type A men (mean age 42 years) were randomly assigned to either an aerobic exercise training group or to a strength and flexibility training group. Before exercise, subjects underwent comprehensive physiologic and behavioral assessment ... Full text Link to item Cite

Cardiovascular responses during upright and semi-recumbent cycle ergometry testing.

Journal article Med Sci Sports Exerc · October 1989 Featured Publication To compare cardiovascular (CV) responses during cycle ergometry testing, 20 unmedicated mild hypertensive subjects (10 male, 10 female; mean age = 47.9 yr) underwent exercise testing on an upright (UP) cycle and a semi-recumbent (SR) cycle. Tests were admi ... Link to item Cite

Type A behavior and survival: a follow-up study of 1,467 patients with coronary artery disease.

Journal article Am J Cardiol · September 1, 1989 Featured Publication Patients with documented coronary artery disease, admitted to Duke Medical Center between 1974 and 1980, were assessed for type A behavior pattern and were followed until 1984. The relation of type A behavior to survival was tested using data from coronary ... Full text Link to item Cite

Improving aerobic capacity in healthy older adults does not necessarily lead to improved cognitive performance.

Journal article Psychol Aging · September 1989 Featured Publication The effects of aerobic exercise training in a sample of 85 older adults were investigated. Ss were assigned randomly to either an aerobic exercise group, a nonaerobic exercise (yoga) group, or a waiting-list control group. Following 16 weeks of the group-s ... Full text Link to item Cite

Cardiovascular and behavioral effects of aerobic exercise training in healthy older men and women.

Journal article J Gerontol · September 1989 Featured Publication The cardiovascular and behavioral adaptations associated with a 4-month program of aerobic exercise training were examined in 101 older men and women (mean age = 67 years). Subjects were randomly assigned to an Aerobic Exercise group, a Yoga and Flexibilit ... Full text Link to item Cite

Psychological effects of exercise among elderly cardiac patients

Journal article Journal of Cardiopulmonary Rehabilitation · January 1, 1989 Aerobic exercise has been associated with improvements not only in physiologic functioning, but also in psychologic functioning. This review examines the effects of exercise on several important aspects of psychologic functioning. Many studies of healthy s ... Full text Cite

Task Force III: Assessment of psychological status in patients with ischemic heart disease

Journal article Journal of the American College of Cardiology · 1989 Cite

Effects of aerobic exercise training on hemodynamic responses during psychosocial stress in normotensive and borderline hypertensive type A men: a preliminary report.

Journal article Psychosom Med · 1989 Featured Publication This study assessed the effects of aerobic exercise training on cardiovascular responses to a 5-min reaction time competition task. Twenty-seven Type A men (aged 30-56) participated in this randomized study in which 14 underwent supervised aerobic training ... Full text Link to item Cite

Cardiovascular responses in the laboratory and in the natural environment: is blood pressure reactivity to laboratory-induced mental stress related to ambulatory blood pressure during everyday life?

Journal article J Psychosom Res · 1989 Featured Publication Cardiovascular activity recorded at rest and during mental stress in the laboratory was studied in relation to ambulatory recorded cardiovascular activity at work and at home. Fifty-five Type A men (M = 42.4 years) underwent a standardized laboratory menta ... Full text Link to item Cite

Slowing of memory-search performance in men with mild hypertension.

Journal article Health Psychol · 1989 Featured Publication Previous reports have associated hypertension with a slowing of cognitive performance, although the component processes involved have not been identified. Our report compares the performance of 24 men with mild hypertension and 28 age-matched normotensive ... Full text Link to item Cite

Effects of aerobic exercise training, age, and physical fitness on memory-search performance.

Journal article Psychol Aging · September 1988 Featured Publication We investigated the effects of exercise training on memory performance. One group of 13 men (M = 42.92 years of age) participated in supervised aerobic exercise (jogging) three times a week for 12 weeks. A second group of 15 men (M = 43.67 years of age) pe ... Full text Link to item Cite

Rehabilitation of patients following myocardial infarction.

Journal article J Consult Clin Psychol · June 1988 Featured Publication Full text Link to item Cite

Effects of beta-blockade and exercise on cardiovascular and cognitive functioning.

Journal article Hypertension · May 1988 Featured Publication Twenty-four men with mild essential hypertension were assigned randomly to receive propranolol (n = 9), atenolol (n = 7), or a placebo (n = 8). All subjects participated in a 12-week study and provided physiological and behavioral data four times during th ... Full text Link to item Cite

Short-term behavioral effects of beta-adrenergic medications in men with mild hypertension.

Journal article Clin Pharmacol Ther · April 1988 Featured Publication beta-Adrenergic-inhibiting drugs are widely prescribed for the treatment of hypertension. These drugs have previously been found to influence a variety of psychologic and behavioral functions and have, in some cases, been associated with serious psychiatri ... Full text Link to item Cite

Lipids, catecholamines, and cardiovascular responses to stress in patients recovering from myocardial infarction

Journal article Journal of Cardiopulmonary Rehabilitation · January 1, 1988 This study examined the relationship of serum lipids to cardiovascular and neuroendocrine responses to a behavioral stressor, the mental arithmetic test (MAT). Forty-two men with a recent (<1 year) myocardial infarction (MI) underwent assessment of blood l ... Full text Cite

Type A behavior and angiographically documented coronary atherosclerosis in a sample of 2,289 patients.

Journal article Psychosom Med · 1988 Featured Publication To determine the relationship between Type A behavior pattern and angiographically documented coronary atherosclerosis (CAD), we analyzed risk factor, behavioral, and angiographic data collected on 2,289 patients undergoing diagnostic coronary angiography ... Full text Link to item Cite

Comparison of high- and low-intensity exercise training early after acute myocardial infarction.

Journal article Am J Cardiol · January 1, 1988 Featured Publication The effects of the intensity of exercise training on cardiorespiratory variables were investigated in a consecutive series of men with recent (median 8 weeks) acute myocardial infarction. Forty-five patients were randomly assigned either to a high- (65 to ... Full text Link to item Cite

Exercise training in healthy type A middle-aged men: effects on behavioral and cardiovascular responses.

Journal article Psychosom Med · 1988 Featured Publication Thirty-six healthy Type A men (means = 44.4 years) were randomly assigned to either an aerobic exercise training group or a strength and flexibility training group. Subjects completed a comprehensive psychological assessment battery before and after the ex ... Full text Link to item Cite

The effects of exercise training on psychosocial functioning after myocardial infarction

Journal article Journal of Cardiopulmonary Rehabilitation · January 1, 1988 This study was designed to assess the effects of exercise on psychosocial functioning in a consecutive series of post myocardial infarction (MI) patients referred for cardiac rehabilitation. Seventy patients with a recent (less than 1 year) MI were randoml ... Full text Cite

Psychological correlates of hostility among patients undergoing coronary angiography.

Journal article Br J Med Psychol · December 1987 Featured Publication The Cook-Medley Hostility (Ho) scale (Cook & Medley, 1954) has been associated with increased risk for coronary heart disease (CHD). There is relatively little information about the psychosocial correlates of the Ho scale in clinical or adult populations, ... Full text Link to item Cite

Medical therapy in the elderly.

Journal article J Am Coll Cardiol · August 1987 Recommendations concerning nutrition and physical activity are an important part of health care in the elderly. There is increasing evidence that diet and exercise influence the development and progression of cardiovascular disease in the elderly as well a ... Full text Link to item Cite

Behavioral approaches to secondary prevention of coronary heart disease.

Journal article Circulation · July 1987 Featured Publication Over the past 10 years behavioral approaches to the treatment of coronary heart disease (CHD) have become widely recognized as being a significant complement to traditional medical and surgical therapies. The success of approaches to secondary prevention n ... Link to item Cite

Nonpharmacologic approaches to the treatment of hypertension.

Journal article Circulation · July 1987 Featured Publication Link to item Cite

Psychological risk factors in coronary artery disease.

Journal article Circulation · July 1987 Featured Publication Link to item Cite

Nucleic acid sequence and oncogenic properties of the HZ2 feline sarcoma virus v-abl insert.

Journal article J Virol · April 1987 Featured Publication Hardy-Zuckerman 2 feline sarcoma virus (HZ2-FeSV), isolated from a multicentric feline fibrosarcoma is a replication-defective acute transforming feline retrovirus which originated by transduction of feline c-abl sequences with feline leukemia virus (FeLV) ... Full text Link to item Cite

Warning: Anger May Be Hazardous to Your Health

Journal article Contemporary Psychology: A Journal of Reviews · March 1987 Full text Cite

Relationships between motivation and hostility among type A and type B middle-aged men

Journal article Journal of Research in Personality · January 1, 1987 Relationships between aspects of personality and the Type A behavior pattern (TABP) were examined in a sample of 60 middle-aged men. TABP classification was determined by the Structured Interview (SI) and the Jenkins Activity Survey (JAS), while aspects of ... Full text Cite

Task force 2: Psychological risk factors in coronary artery disease

Journal article Circulation · January 1, 1987 Cite

Social support, type A behavior, and coronary artery disease.

Journal article Psychosom Med · 1987 Featured Publication The interaction of Type A behavior and social support in relation to the degree of coronary artery disease (CAD) severity was investigated. One hundred thirteen patients undergoing diagnostic coronary angiography received the Type A structured interview (S ... Full text Link to item Cite

Behavioral approaches to secondary prevention of coronary heart disease

Journal article Circulation · 1987 Over the past 10 years behavioral approaches to the treatment of coronary heart disease (CHD) have become widely recognized as being a significant complement to traditional medical and surgical therapies. The success of approaches to secondary prevention n ... Cite

Relationships between motivation and hostility among type A and type B middle-aged men

Journal article Journal of Research in Personality · 1987 Relationships between aspects of personality and the Type A behavior pattern (TABP) were examined in a sample of 60 middle-aged men. TABP classification was determined by the Structured Interview (SI) and the Jenkins Activity Survey (JAS), while aspects of ... Cite

Behavioral approaches to secondary prevention of coronary heart disease

Journal article Circulation · January 1, 1987 Over the past 10 years behavioral approaches to the treatment of coronary heart disease (CHD) have become widely recognized as being a significant complement to traditional medical and surgical therapies. The success of approaches to secondary prevention n ... Cite

Angina pectoris in type A and type B cardiac patients.

Journal article Pain · November 1986 Featured Publication The type A behavior pattern is characterized by excessive competitive drive, a sense of time urgency, enhanced aggressiveness, hostility and a persistent desire for recognition. Type A behaviour is widely recognized as a risk factor in coronary heart disea ... Full text Link to item Cite

Type As who think they are type Bs: discrepancies between self-ratings and interview ratings of the type A (coronary-prone) behaviour pattern.

Journal article Br J Med Psychol · March 1986 Featured Publication The study described here explored discrepancies between self-ratings and interview ratings of Type A behaviour. A total of 281 patients referred for diagnostic coronary angiography underwent a comprehensive psychological assessment including the Type A str ... Full text Link to item Cite

Communication to the editor: Response to Bass

Journal article Journal of Psychosomatic Research · 1986 Cite

Psychosocial and physical predictors of anginal pain relief with medical management.

Journal article Psychosom Med · 1986 Featured Publication This study was undertaken to identify psychosocial and physical characteristics that independently predict anginal pain relief. The original study group comprised over 570 patients in whom the characteristics were identified at the time of coronary arterio ... Full text Link to item Cite

Memory performance by mild hypertensives following beta-adrenergic blockade.

Journal article Psychopharmacology (Berl) · 1986 Featured Publication Previous experiments have reported deficits in cognitive performance following the administration of beta-adrenoceptor antagonists. These deficits have not appeared consistently, however, and it is not clear from previous studies whether changes in the cen ... Full text Link to item Cite

Relationships among age, sex, the type A behavior pattern, and cardiovascular reactivity.

Journal article J Gerontol · November 1985 Featured Publication Most investigations of Type A behavior and cardiovascular responsivity have used age-homogeneous, male samples. In this study, heart rate (HR) and blood pressure responses were obtained from men and women, age 27 to 70, during mental arithmetic and a visua ... Full text Link to item Cite

Age differences in self-perceptions of type A traits.

Journal article J Consult Clin Psychol · April 1985 Featured Publication Full text Link to item Cite

In Reply

Journal article JAMA the Journal of the American Medical Association · February 15, 1985 Full text Cite

Psychologic assessment in cardiac rehabilitation

Journal article Journal of Cardiac Rehabilitation · January 1, 1985 Coronary heart disease (CHD) is a condition with significant psychologic and social, as well as physical, consequences. As such, psychologic assessment is an important component of any cardiac rehabilitation (CR) program. A multidimensional framework is pr ... Full text Cite

Relaxation therapy, biofeedback, and behavioral medicine

Journal article Psychotherapy · January 1, 1985 Psychologists have become increasingly involved in the assessment and treatment of patients with medical disorders. A new field known as Behavioral Medicine has recently emerged as an area concerned with the integration of behavioral and biomedical science ... Full text Cite

Components of Type A, hostility, and anger-in: relationship to angiographic findings.

Journal article Psychosom Med · 1985 Featured Publication Previous research has linked the Type A coronary-prone behavior pattern to angiographically documented severity of coronary atherosclerosis (CAD). The present study sought through component scoring of the Type A Structured Interview (SI) to determine what ... Full text Link to item Cite

Development of a brief self-report measure of the type A (coronary prone) behavior pattern.

Journal article J Psychosom Res · 1985 Featured Publication This study reports the development of a brief self-report measure of the Type A behavior pattern based upon a set of adjectives derived from the Gough Adjective Checklist (ACL). Previous work from our laboratory established a set of adjectives identified b ... Full text Link to item Cite

The inhibited power motive, type A behavior, and patterns of cardiovascular response during the structured interview and Thematic Apperception Test.

Journal article J Human Stress · 1985 Featured Publication The Type A behavior pattern and the inhibited power motive have been implicated in the development of coronary heart disease (CHD). Since it is widely believed that enhanced cardiovascular responsivity may be one mechanism by which individuals develop CHD, ... Full text Link to item Cite

Is running an analogue of anorexia nervosa? An empirical study of obligatory running and anorexia nervosa.

Journal article JAMA · July 27, 1984 Featured Publication A recent report suggested that compulsive runners share a common set of psychological traits and behavioral dispositions with patients with anorexia nervosa. In an effort to objectively assess the similarity between anorexia nervosa and obligatory running, ... Link to item Cite

Feasibility and benefits of exercise training in patients on maintenance dialysis.

Journal article Kidney Int · June 1984 Featured Publication Fourteen of 174 patients receiving maintenance dialysis volunteered to participate in a 12-week exercise conditioning program. Seven patients attended more than 50% (range, 55 to 75%) of the sessions held three times each week. These seven patients achieve ... Full text Link to item Cite

Behavioral assessment of the type A behavior pattern.

Journal article Psychosom Med · 1984 Featured Publication The present study attempted to assess systematically a set of behavioral subcomponents associated with the Type A behavior pattern. Sixty middle-aged men underwent the structured interview (SI) and a repeated version of the SI after a four-month interval. ... Full text Link to item Cite

Physical conditioning and left ventricular performance in the elderly: assessment by radionuclide angiocardiography.

Journal article Am J Cardiol · August 1983 Featured Publication In contrast to young persons, normal elderly persons who undergo symptom-limited dynamic exercise demonstrate a decrease in left ventricular (LV) contractile performance characterized by a decrease in LV ejection fraction. To test the hypothesis that physi ... Full text Link to item Cite

Cardiac Rehabilitation: A new frontier for behavioral medicine

Journal article Journal of Cardiac Rehabilitation · 1983 Cite

Continuing medical education cardiac rehabilitation: A new frontier for behavioral medicine

Journal article Journal of Cardiac Rehabilitation · January 1, 1983 Secondary prevention of coronary disease has traditionally involved primarily surgery and pharmacologic management. However, it has become increasingly evident that successful rehabilitation also involves modification of those overt behaviors that place ca ... Cite

PATTERNS OF CARDIOVASCULAR-RESPONSE IN TYPE-A AND TYPE-B MALES

Journal article PSYCHOPHYSIOLOGY · January 1, 1983 Link to item Cite

Psychological changes accompany aerobic exercise in healthy middle-aged adults.

Journal article Psychosom Med · December 1982 Featured Publication An attempt was made to assess the effects of aerobic exercise on the psychological functioning of a nonclinical sample of healthy middle-aged adults. Sixteen subjects participated in a 10-week program of regular walking-jogging, while a matched control gro ... Full text Link to item Cite

Physiological and psychological variables predict compliance to prescribed exercise therapy in patients recovering from myocardial infarction.

Journal article Psychosom Med · December 1982 Featured Publication Previous research has documented high rates of noncompliance to prescribed medical therapy in patients recovering from myocardial infarction (MI). This study was undertaken to determine if patients who subsequently drop out of a structured cardiac rehabili ... Full text Link to item Cite

Duke University's Preventive Approach to Cardiology - DUPAC

Journal article Journal of Cardiac Rehabilitation · 1982 Cite

Psychological and physiological effects of physical conditioning on the elderly.

Journal article J Psychosom Res · 1982 Featured Publication A decline in cardiovascular functioning is generally thought to occur with advancing age. The purpose of the present study was to assess the effects of regular aerobic exercise on a group of 24 young-old (65-69) and old-old (70-85 yr) volunteers. Comprehen ... Full text Link to item Cite

Self-ratings of type A (coronary prone) adults: do type A's know they are type A's?

Journal article Psychosom Med · October 1981 Featured Publication This study compared self-ratings and interview-band ratings of the type A coronary-prone behavior pattern. A Type A adjective scale was developed from the Gough-Adjective Checklist (ACL), using adjectives rated as characteristic and uncharacteristic of the ... Full text Link to item Cite

Assessment of conceptual tempo in the type A (coronary prone) behavior pattern.

Journal article J Pers Assess · February 1981 Featured Publication Previous research has documented an association between a particular behavioral complex termed Type A, and increased incidence of coronary heart disease. In an effort to define further some of the behavioral characteristics that distinguish Type A subjects ... Full text Link to item Cite

Assessment of conceptual tempo in the Type A (coronary prone) behavior pattern

Journal article Journal of Personality Assessment · 1981 Cite

9: 30 a.m.: PSYCHOLOGICAL CHANGES ACCOMPANYING PHYSICAL EXERCISE: A CONTROLLED STUDY

Journal article Medicine & Science in Sports & Exercise · 1981 Full text Cite

Anxiety and Emotions: Physiological Basis and Treatment

Journal article Psychosomatic Medicine · November 1980 Full text Cite

Type A behavior, hostility, and coronary atherosclerosis.

Journal article Psychosom Med · November 1980 Featured Publication Type A behavior pattern was assessed using the structured interview and hostility level was assessed using a subscale of the Minnesota Multiphase Personality Inventory in 424 patients who underwent diagnostic coronary arteriography for suspected coronary h ... Full text Link to item Cite

Effects of exercise on the Type A (coronary prone) behavior pattern.

Journal article Psychosom Med · March 1980 Featured Publication This study presents the initial findings of an attempt to reduce the risk of coronary heart disease (CHD) in a group of health, middle-aged adults by participation in a ten-week, supervised exercise program. Forty-six subjects were classified as Type A or ... Full text Link to item Cite

The effects of exercise on the Type A behavior pattern

Journal article Psychosomatic Medicine · 1980 Cite

The life fitness program: A behavioral approach to making exercise a habit

Journal article Journal of Behavior Therapy and Experimental Psychiatry · January 1, 1980 Difficulty in maitaining exercise regimens over long time periods is a common problem. This study examined the efficacy of a combination of stimulus control and self- reinforcement procedures in the acquisition and maintenance of a walking exercise program ... Full text Cite

Task Incentives, Type A Behavior Pattern, and Verbal Problem Solving Performance

Journal article Journal of Applied Social Psychology · January 1, 1980 A laboratory experiment was conducted to investigate the interaction between task incentives and the Type A behavior pattern in determining performance during a task of verbal problem solving. The results indicated that Type A subjects responded more quick ... Full text Cite

Anxiety-proneness and coronary heart disease.

Journal article J Psychosom Res · 1979 Featured Publication Full text Link to item Cite

Type A behavior pattern and coronary atherosclerosis.

Journal article Circulation · October 1978 Featured Publication Previous research has demonstrated an increased rate of clinical coronary heart disease (CHD) events among people who exhibit a "coronary prone" (Type A) behavior pattern. This study was undertaken to determine whether the association between behavior patt ... Full text Link to item Cite

Treatment of thrombosed hemorrhoids by excision.

Journal article Am J Surg · October 1970 Featured Publication Full text Link to item Cite