Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Residency, Johns Hopkins University School of Medicine 2019 - 2022
  • M.D., University of Pittsburgh, School of Medicine 2018
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Wei, Junchao, Yi Hua, Bin Yang, Bo Wang, Samantha E. Schmitt, Bingrui Wang, Katie A. Lucy, et al. “Comparing Acute IOP-Induced Lamina Cribrosa Deformations Premortem and Postmortem.” Transl Vis Sci Technol 11, no. 12 (December 1, 2022): 1. https://doi.org/10.1167/tvst.11.12.1.
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    • Glidai, Yoav, Katie A. Lucy, Joel S. Schuman, Palaiologos Alexopoulos, Bo Wang, Mengfei Wu, Mengling Liu, et al. “Microstructural Deformations Within the Depth of the Lamina Cribrosa in Response to Acute In Vivo Intraocular Pressure Modulation.” Invest Ophthalmol Vis Sci 63, no. 5 (May 2, 2022): 25. https://doi.org/10.1167/iovs.63.5.25.
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    • Zhong, Fuqiang, Bingrui Wang, Junchao Wei, Yi Hua, Bo Wang, Juan Reynaud, Brad Fortune, and Ian A. Sigal. “A high-accuracy and high-efficiency digital volume correlation method to characterize in-vivo optic nerve head biomechanics from optical coherence tomography.” Acta Biomater 143 (April 15, 2022): 72–86. https://doi.org/10.1016/j.actbio.2022.02.021.
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    • Zhu, Ziyi, Susannah Waxman, Bo Wang, Jacob Wallace, Samantha E. Schmitt, Elizabeth Tyler-Kabara, Hiroshi Ishikawa, et al. “Interplay between intraocular and intracranial pressure effects on the optic nerve head in vivo.” Exp Eye Res 213 (December 2021): 108809. https://doi.org/10.1016/j.exer.2021.108809.
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    • Wang, Bo, Katie A. Lucy, Joel S. Schuman, Ian A. Sigal, Richard A. Bilonick, Chen Lu, Jonathan Liu, et al. “Tortuous Pore Path Through the Glaucomatous Lamina Cribrosa.” Sci Rep 8, no. 1 (May 8, 2018): 7281. https://doi.org/10.1038/s41598-018-25645-9.
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    • Wang, Bo, Katie A. Lucy, Joel S. Schuman, Hiroshi Ishikawa, Richard A. Bilonick, Ian A. Sigal, Larry Kagemann, Chen Lu, James G. Fujimoto, and Gadi Wollstein. “Location of the Central Retinal Vessel Trunk in the Laminar and Prelaminar Tissue of Healthy and Glaucomatous Eyes.” Sci Rep 7, no. 1 (August 30, 2017): 9930. https://doi.org/10.1038/s41598-017-10042-5.
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    • Dong, Zachary M., Gadi Wollstein, Bo Wang, and Joel S. Schuman. “Adaptive optics optical coherence tomography in glaucoma.” Prog Retin Eye Res 57 (March 2017): 76–88. https://doi.org/10.1016/j.preteyeres.2016.11.001.
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    • Lucy, Katie A., Bo Wang, Joel S. Schuman, Richard A. Bilonick, Yun Ling, Larry Kagemann, Ian A. Sigal, et al. “Thick Prelaminar Tissue Decreases Lamina Cribrosa Visibility.” Invest Ophthalmol Vis Sci 58, no. 3 (March 1, 2017): 1751–57. https://doi.org/10.1167/iovs.16-20784.
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    • Wang, Bo, Huong Tran, Matthew A. Smith, Tigran Kostanyan, Samantha E. Schmitt, Richard A. Bilonick, Ning-Jiun Jan, et al. “In-vivo effects of intraocular and intracranial pressures on the lamina cribrosa microstructure.” Plos One 12, no. 11 (2017): e0188302. https://doi.org/10.1371/journal.pone.0188302.
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    • Murphy, Matthew C., Ian P. Conner, Cindy Y. Teng, Jesse D. Lawrence, Zaid Safiullah, Bo Wang, Richard A. Bilonick, et al. “Retinal Structures and Visual Cortex Activity are Impaired Prior to Clinical Vision Loss in Glaucoma.” Sci Rep 6 (August 11, 2016): 31464. https://doi.org/10.1038/srep31464.
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    • Wang, Bo, Katie A. Lucy, Joel S. Schuman, Ian A. Sigal, Richard A. Bilonick, Larry Kagemann, Tigran Kostanyan, et al. “Decreased Lamina Cribrosa Beam Thickness and Pore Diameter Relative to Distance From the Central Retinal Vessel Trunk.” Invest Ophthalmol Vis Sci 57, no. 7 (June 1, 2016): 3088–92. https://doi.org/10.1167/iovs.15-19010.
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    • Kagemann, Larry, Bo Wang, Gadi Wollstein, Hiroshi Ishikawa, Brandon Mentley, Ian Sigal, Richard A. Bilonick, and Joel S. Schuman. “Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye.” J Vis Exp, no. 100 (June 20, 2015): e52611. https://doi.org/10.3791/52611.
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    • Ho, Leon C., Bo Wang, Ian P. Conner, Yolandi van der Merwe, Richard A. Bilonick, Seong-Gi Kim, Ed X. Wu, et al. “In Vivo Evaluation of White Matter Integrity and Anterograde Transport in Visual System After Excitotoxic Retinal Injury With Multimodal MRI and OCT.” Invest Ophthalmol Vis Sci 56, no. 6 (June 2015): 3788–3800. https://doi.org/10.1167/iovs.14-15552.
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    • Nadler, Zach, Bo Wang, Joel S. Schuman, R Daniel Ferguson, Ankit Patel, Daniel X. Hammer, Richard A. Bilonick, et al. “In vivo three-dimensional characterization of the healthy human lamina cribrosa with adaptive optics spectral-domain optical coherence tomography.” Invest Ophthalmol Vis Sci 55, no. 10 (September 16, 2014): 6459–66. https://doi.org/10.1167/iovs.14-15177.
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    • Sigal, Ian A., Bo Wang, Nicholas G. Strouthidis, Tadamichi Akagi, and Michael J. A. Girard. “Recent advances in OCT imaging of the lamina cribrosa.” Br J Ophthalmol 98 Suppl 2, no. Suppl 2 (July 2014): ii34–39. https://doi.org/10.1136/bjophthalmol-2013-304751.
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    • Nadler, Z., B. Wang, G. Wollstein, J. E. Nevins, H. Ishikawa, R. Bilonick, L. Kagemann, et al. “Repeatability of in vivo 3D lamina cribrosa microarchitecture using adaptive optics spectral domain optical coherence tomography.” Biomedical Optics Express 5, no. 4 (April 1, 2014): 1114–23. https://doi.org/10.1364/BOE.5.001114.
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    • Kagemann, Larry, Bo Wang, Gadi Wollstein, Hiroshi Ishikawa, Jessica E. Nevins, Zach Nadler, Ian A. Sigal, Richard A. Bilonick, and Joel S. Schuman. “IOP elevation reduces Schlemm's canal cross-sectional area.” Invest Ophthalmol Vis Sci 55, no. 3 (March 25, 2014): 1805–9. https://doi.org/10.1167/iovs.13-13264.
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    • Wang, Bo, Jessica E. Nevins, Zach Nadler, Gadi Wollstein, Hiroshi Ishikawa, Richard A. Bilonick, Larry Kagemann, et al. “Reproducibility of in-vivo OCT measured three-dimensional human lamina cribrosa microarchitecture.” Plos One 9, no. 4 (2014): e95526. https://doi.org/10.1371/journal.pone.0095526.
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    • Wang, Bo, Larry Kagemann, Joel S. Schuman, Hiroshi Ishikawa, Richard A. Bilonick, Yun Ling, Ian A. Sigal, et al. “Gold nanorods as a contrast agent for Doppler optical coherence tomography.” Plos One 9, no. 3 (2014): e90690. https://doi.org/10.1371/journal.pone.0090690.
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    • Wang, Bo, Jessica E. Nevins, Zach Nadler, Gadi Wollstein, Hiroshi Ishikawa, Richard A. Bilonick, Larry Kagemann, et al. “In vivo lamina cribrosa micro-architecture in healthy and glaucomatous eyes as assessed by optical coherence tomography.” Invest Ophthalmol Vis Sci 54, no. 13 (December 19, 2013): 8270–74. https://doi.org/10.1167/iovs.13-13109.
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    • Nadler, Z., B. Wang, G. Wollstein, J. E. Nevins, H. Ishikawa, L. Kagemann, I. A. Sigal, et al. “Automated lamina cribrosa microstructural segmentation in optical coherence tomography scans of healthy and glaucomatous eyes.” Biomedical Optics Express 4, no. 11 (November 1, 2013): 2596–2608. https://doi.org/10.1364/BOE.4.002596.
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    • Francis, Andrew W., Larry Kagemann, Gadi Wollstein, Hiroshi Ishikawa, Steven Folz, Darryl R. Overby, Ian A. Sigal, Bo Wang, and Joel S. Schuman. “Morphometric analysis of aqueous humor outflow structures with spectral-domain optical coherence tomography.” Invest Ophthalmol Vis Sci 53, no. 9 (August 7, 2012): 5198–5207. https://doi.org/10.1167/iovs.11-9229.
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  • Book Sections

    • Wang, B., G. Wollstein, and J. S. Schuman. “Optic nerve: Optical coherence tomography.” In Pearls of Glaucoma Management: Second Edition, 51–61, 2016. https://doi.org/10.1007/978-3-662-49042-6_5.
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  • Conference Papers

    • Wei, J., B. Yang, A. P. Voorhees, H. Tran, B. Brazile, B. Wang, J. Schuman, M. A. Smith, G. Wollstein, and I. A. Sigal. “Measuring in-vivo and in-situ ex-vivo the 3D deformation of the lamina cribrosa microstructure under elevated intraocular pressure.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 10496, 2018. https://doi.org/10.1117/12.2291243.
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    • Tran, H., J. Grimm, B. Wang, M. A. Smith, A. Gogola, S. Nelson, E. Tyler-Kabara, J. Schuman, G. Wollstein, and I. A. Sigal. “Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 10067, 2017. https://doi.org/10.1117/12.2257360.
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    • Horvath, S., J. Galeotti, B. Wang, M. Perich, J. Wang, M. Siegel, P. Vescovi, and G. Stetten. “Towards an ultrasound probe with vision: Structured light to determine surface orientation.” In Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 7264 LNCS:58–64, 2012. https://doi.org/10.1007/978-3-642-32630-1_6.
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    • Samosky, J. T., D. A. Nelson, B. Wang, R. Bregman, A. Hosmer, B. Mikulis, and R. Weaver. “BodyExplorerAR: Enhancing a mannequin medical simulator with sensing and projective augmented reality for exploring dynamic anatomy and physiology.” In Proceedings of the 6th International Conference on Tangible, Embedded and Embodied Interaction, Tei 2012, 263–70, 2012. https://doi.org/10.1145/2148131.2148187.
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    • Samosky, Joseph T., Bo Wang, Douglas A. Nelson, Russell Bregman, Andrew Hosmer, and Robert A. Weaver. “BodyWindows: enhancing a mannequin with projective augmented reality for exploring anatomy, physiology and medical procedures.” In Stud Health Technol Inform, 173:433–39, 2012.
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    • Stetten, G., S. Horvath, J. Galeotti, G. Shukla, B. Wang, and B. Chapman. “Image segmentation using the student's t-test and the divergence of direction on spherical regions.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 7623, 2010. https://doi.org/10.1117/12.844014.
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    • Galeotti, J., A. Sajjad, B. Wang, L. Kagemann, G. Shukla, M. Siegel, B. Wu, et al. “The OCT penlight: In-situ image guidance for microsurgery.” In Progress in Biomedical Optics and Imaging  Proceedings of Spie, Vol. 7625, 2010. https://doi.org/10.1117/12.844411.
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