Current Appointments & Affiliations
Assistant Professor in Pediatrics
·
2023 - Present
Pediatrics, Nephrology,
Pediatrics
Recent Publications
Natural History and Clinicopathological Associations of TRPC6-Associated Podocytopathy.
Journal Article J Am Soc Nephrol · February 1, 2025 KEY POINTS: We conducted a clinical, genetic, and pathological analysis on 64 cases from 39 families with TRPC6-associated podocytopathy (TRPC6-AP). Analysis of 37,542 individuals excluded a major contribution of loss-of-function variants to TRPC6-AP, legi ... Full text Link to item CiteStrong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease.
Journal Article Nat Commun · November 30, 2023 African Americans have a significantly higher risk of developing chronic kidney disease, especially focal segmental glomerulosclerosis -, than European Americans. Two coding variants (G1 and G2) in the APOL1 gene play a major role in this disparity. While ... Full text Link to item CiteInaxaplin for the treatment of APOL1-associated kidney disease.
Journal Article Nat Rev Nephrol · August 2023 Chronic kidney disease (CKD) is highly prevalent World-Wide and it is an important cause of morbidity and mortality. In 2010, variants in apolipoprotein type 1 (APOL1) gene was identified as a major risk factor for higher prevalence of CKD in individuals o ... Full text Link to item CiteRecent Grants
REGULATORS OF CALCINEURIN PATHWAYS AS DIAGNOSTIC AND THERAPEUTIC TARGETS FOR NEPHROTIC SYNDROME
ResearchInvestigator · Awarded by National Institutes of Health · 2023 - 2026Defining the role of chloride channel 5 in maintaining podocyte structure and functions
ResearchInvestigator · Awarded by NEPHCURE Kidney International · 2023 - 2025Defining the Landscape of HLA Risk Alleles in Primary Nephrotic Syndrome and Post Kidney Transplant Recurrence
ResearchResearch Professional · Awarded by National Institutes of Health · 2020 - 2025View All Grants
Education, Training & Certifications
Virginia Commonwealth University, School of Medicine ·
2012
Ph.D.