Journal articleSpine Surgery and Related Research · July 27, 2026
Introduction: Trisomy 18 is a chromosomal abnormality with an estimated prevalence of 4.8 per 10,000 births. The condition is associated with scoliosis; however, the nature of this relationship is incompletely understood, as historically the 1-year mortali ...
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Journal articlePain Manag · July 26, 2026
INTRODUCTION: Concerns over postoperative opioid use after open spinal fusion continue to rise. Many randomized controlled trials (RCTs) have sought to reduce postoperative opioid consumption; however, the influence of sociodemographic variables on this co ...
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Journal articleJ Neurosurg Case Lessons · July 20, 2026
BACKGROUND: Pelvic fixation failure (PFF) remains prevalent in adult spinal deformity correction, with failure rates up to 35%. Current revision surgeries are highly invasive and morbid, requiring extensive incisions and recovery times. Sacroiliac joint fu ...
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Journal articleElectronics Switzerland · June 1, 2026
“Spinal cord stimulation (SCS)” is an established therapy for chronic pain and an emerging modality for functional recovery after spinal cord injury (SCI) and other clinical applications. Despite its clinical potential, current implantable SCS systems rema ...
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Journal articleSpine (Phila Pa 1976) · May 21, 2026
STUDY DESIGN: Retrospective single-center study. OBJECTIVE: We aim to compare the prognostic capacity of postoperative T4-L1PA mismatch versus T4PA and L1PA alone. SUMMARY OF BACKGROUND DATA: The assessment of T4-L1PA mismatch, the difference between tradi ...
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Journal articleSpine Deform · May 16, 2026
PURPOSE: Early deep wound infection complicates an estimated 4% of posterior lumbosacral fusions, increasing mortality and hospitalization costs. The objective of this study was to characterize causative organisms and risk factors of deep wound infections ...
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Journal articleGlobal Spine J · March 2026
Study designLiterature review with clinical recommendation.ObjectivesTo provide the readers with a concise curation of the relevant spine literature regarding the identification and management of osteoporosis in patients with adult spinal deformity (ASD) a ...
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Journal articleSpine Deform · March 2026
PURPOSE: Despite evidence for the safety and efficacy of zoledronate infusions in pediatric conditions (e.g., osteogenesis imperfecta), its tolerance, safety, and efficacy in medically complex children with neuromuscular scoliosis have not been established ...
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Journal articleN Am Spine Soc J · March 2026
BACKGROUND: Large language models (LLMs) like ChatGPT are increasingly being recognized as credible tools for use across diverse healthcare settings. While artificial intelligence (AI) use has previously been evaluated in emergency medicine, its use in sub ...
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Journal articleJMIR Res Protoc · November 17, 2025
BACKGROUND: Spine surgery is increasingly common in the United States, contributing substantially to spine-related health care costs. While many patients benefit, up to 25% experience chronic postsurgical pain, and the procedure is linked to high rates of ...
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Journal articleJ Pediatr Orthop B · November 1, 2025
Achieving a rapid diagnosis in suspected septic arthritis is challenging as a pathogen is only isolated in 50% of cases, and the necessary investigation takes time and delays treatment. The alpha-defensin lateral flow test (Synovasure) has been shown to ef ...
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Journal articleGlobal Spine J · July 2025
Study DesignNarrative literature review.ObjectivesTo summarize the evidence for perioperative blood conservation for patients undergoing surgery for adult spine deformity.MethodsA systematic literature review with narrative analysis was conducted to descri ...
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Journal articleGlobal Spine J · July 2025
Study DesignNarrative Literature Review.ObjectiveTo provide a comprehensive literature review of neurologic complications in Adult Spinal Deformity (ASD) surgery in the pre-operative, peri-operative and post-operative periods.MethodsA broad review of the l ...
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Journal articleJ Orthop Case Rep · July 2025
INTRODUCTION: Many options have been described to restore balance and create stable fusion in severe adolescent idiopathic scoliosis (AIS), including preoperative gravity halo traction, posterior vertebral column resection, and three column osteotomies. Un ...
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Journal articleCureus · May 2025
PURPOSE: How specific active areas on Single Photon Emission Computed Tomography-Computerized Tomography (SPECT-CT) inform management for chronic low back pain (CLBP) is limited. This study aimed to assess the relationship between SPECT-CT uptake locations ...
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Journal articleJMIR Form Res · April 29, 2025
BACKGROUND: Adult spinal deformity (ASD) is a prevalent condition estimated at 38%. Symptomatic ASD is associated with substantial health care costs. The role of nonoperative interventions in the management of ASD remains elusive. The National Scoliosis Cl ...
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Journal articleGlobal Spine J · April 2025
Study DesignProspective multicenter database post-hoc analysis.ObjectivesOpioids are frequently prescribed for painful spinal conditions to provide pain relief and to allow for functional improvement, both before and after spine surgery. Amidst a current o ...
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Journal articleGlobal Spine J · March 2025
STUDY DESIGN: Cross-sectional international survey with literature review. OBJECTIVES: To evaluate the evidence for these strategies and to understand the current trends in prophylactic antibiotic use during ASD surgery through an international survey. MET ...
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Journal articleJ Pediatr Orthop · March 1, 2025
BACKGROUND: Although 10% to 60% of patients with Down syndrome (DS) develop atlantoaxial instability (AAI), clarifying the course of asymptomatic AAI may prevent unnecessary clinical interactions and investigations. This study investigates the radiographic ...
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Journal articleNeurosurgery · March 1, 2025
Minimally invasive surgery (MIS) has significantly revolutionized spine surgery by reducing morbidity, minimizing tissue damage, and improving postoperative outcomes compared with traditional open surgeries. Although MIS is well-documented for degenerative ...
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Journal articleBone Joint J · March 1, 2025
AIMS: The T1 pelvic angle (T1PA) provides a consistent global measure of sagittal alignment independent of compensatory mechanisms and positional changes. However, it may not explicitly reflect alignment goals that correlate with a lower risk of complicati ...
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Journal articleClin Spine Surg · February 1, 2025
STUDY DESIGN: Retrospective Analysis. OBJECTIVE: The objective of the study was to assess the impact of academic productivity at both individual and program levels on lifetime industry earnings within US orthopedic spine fellowships. SUMMARY OF BACKGROUND ...
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Journal articleJ Pediatr Orthop · January 1, 2025
BACKGROUND: Children with neuromuscular scoliosis undergoing scoliosis surgery face substantial rates of complications. To mitigate surgical risks such as blood loss in pediatric patients with neuromuscular scoliosis, this study focuses on enabling instrum ...
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Journal articleTurk J Med Sci · 2025
Osteobiologics are increasingly used in orthopedics and spine surgery to facilitate bone healing and prevent nonunion. Synthetic osteobiologics are artificial materials crafted in laboratories that aim to replicate the natural composition and functionality ...
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Journal articleCureus · January 2025
Deep spinal surgical site infections (SSIs) following spine surgery pose a significant concern, with management becoming even more complex and high-risk in pregnant patients with spinal instrumentation. The optimal approach to managing this rare scenario r ...
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Journal articleN Am Spine Soc J · December 2024
BACKGROUND: Traumatic thoracolumbar fracture fixation without neurological injury can be performed using the traditional open, mini-open Wiltse, and percutaneous approaches. This systematic review and meta-analysis aims to compare perioperative outcomes be ...
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Journal articleWorld Neurosurg · June 2024
OBJECTIVE: To analyze the extant literature describing the application of gene therapy to spinal fusion. METHODS: A systematic review of the English-language literature was performed. The search query was designed to include all published studies examining ...
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Journal articleSpine (Phila Pa 1976) · April 1, 2024
STUDY DESIGN: A systematic review and meta-analysis. OBJECTIVE: The objective of this study is to examine the impact of the learning curve for endoscopic cervical foraminotomy for clinical outcomes and patient safety. SUMMARY OF BACKGROUND DATA: Endoscopic ...
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Journal articleCureus · April 2024
The correction of anemia is important in reversing significant intraoperative bilateral motor-evoked potential (MEP) loss following rod placement for correction of large scoliosis curves. This article presents a retrospective review of intraoperative neuro ...
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Journal articleSpine surgery and related research · March 2024
IntroductionThe advancement of surgical techniques and perioperative management for congenital heart disease (CHD) has increased life expectancy. The surgical creation of the Fontan circulation maintains pulmonary blood flow without relying on an ...
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Journal articlePLoS One · 2024
STUDY DESIGN: Cross-sectional international survey with a literature review. OBJECTIVES: While some surgeons favor spine bracing after surgery for adult spine deformity (ASD) to help prevent mechanical failures, there is a lack of evidence. The objective o ...
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Journal articleInt J Spine Surg · December 27, 2023
Spinal fusion is important for the clinical success of patients undergoing surgery, and the immune system plays an increasingly recognized role. Osteoimmunology is the study of the interactions between the immune system and bone. Inflammation impacts the o ...
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Journal articleSpine J · December 2023
BACKGROUND CONTEXT: Intraoperative neuromonitoring (IONM) during surgical correction of spinal deformity has been shown to reduce iatrogenic injury in pediatric and adult populations. Although motor-evoked potentials (MEP), somatosensory-evoked potentials ...
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Journal articleActa Neurochir (Wien) · November 2023
INTRODUCTION: The integration of novel electronic informed consent platforms in healthcare has undergone significant growth over the last decade. Adoption of uniform, accessible, and robust electronic online consenting applications is likely to enhance the ...
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Journal articleSpine Deform · September 2023
PURPOSE: Postoperative surgical site infection in patients treated with lumbosacral fusion has usually been thought to be caused by perioperative contamination. With the proximity of these incisions to the perineum, this study sought to determine if contam ...
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Journal articleJ Pediatr Orthop B · July 1, 2023
Costello syndrome (CS) is a rare genetic condition caused by a heterozygous mutation in the HRAS gene, with an estimated prevalence of 1: 300 000. Individuals with CS present with characteristic features including scoliosis, kyphosis, Chiari 1 malformation ...
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Journal articleJournal of Children S Orthopaedics · April 1, 2023
Purpose: Managing severe scoliosis is challenging and risky with a significant complication rate regardless of treatment strategy. In this retrospective comparative study, we report our results using a three-rod compared to two-rod construct in the surgica ...
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Journal articleSpine (Phila Pa 1976) · March 1, 2023
STUDY DESIGN: Prospective randomized control trial. OBJECTIVE: To analyze outcomes following the injection of cerebrolysin in surgically treated patients with degenerative cervical myelopathy (DCM). SUMMARY OF BACKGROUND DATA: Previous research has conclud ...
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Journal articleEur Spine J · February 2023
PURPOSE: There is currently no consensus on the management of high-grade spondylolisthesis (HGS) in paediatric populations. The objective of this analysis is to compare the outcomes of reduction followed by fusion (RFF) or in situ fusion (ISF) in paediatri ...
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Journal articlePediatr Int · 2023
BACKGROUND: The RASopathies (Noonan syndrome [NS] and Costello syndrome [CS]) are rare disorders. Although these have been characterized, precise delineation of the differences in the spinal deformities associated with RASopathy has not been described. Thi ...
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Journal articleJBJS Case Connect · October 1, 2022
CASES: A retrospective chart and radiographic review was performed of 3 patients presenting with neurological deficits secondary to soft thoracic disc herniation associated with proximal junctional kyphosis. The patients were treated with proximal extensio ...
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Journal articleSpine Deform · September 2022
PURPOSE: An essential component of making the diagnosis of adolescent idiopathic scoliosis (AIS) is standing anteroposterior and lateral radiographs. Two-dimensional (2D) radiographs inevitably fail to reflect every plane of the three-dimensional (3D) defo ...
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Journal articleSpine Deform · September 2022
PURPOSE: Residual shoulder imbalance is associated with suboptimal outcomes following the surgical correction of adolescent idiopathic scoliosis (AIS) including poor patient satisfaction. In this retrospective study, we evaluate the radiographic parameters ...
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Journal articleSpine (Phila Pa 1976) · January 15, 2022
STUDY DESIGN: Prospective randomized control trial. OBJECTIVE: The aim of this study was to analyze role of cerebrolysin in patients of degenerative cervical myelopathy (DCM) managed by surgical modalities. SUMMARY OF BACKGROUND DATA: Cerebrolysin has been ...
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Journal articleIndian Spine Journal · January 1, 2022
Traumatic spinal cord injuries (SCIs) have devastating physical, social, and financial consequences for both patients and their families. SCIs most frequently occur at the cervical spine level, and these injuries are particularly prone to causing debilitat ...
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Journal articleTomography · October 22, 2021
Background: Pedicle screws provide excellent fixation for a wide range of indications. However, their adoption in the cervical spine has been slower than in the thoracic and lumbar spine, which is largely due to the smaller pedicle sizes and the proximity ...
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Journal articleSpine (Phila Pa 1976) · October 15, 2021
STUDY DESIGN: A multicenter retrospective review of consecutive series of patients. OBJECTIVE: Long-term experience with using the magnetically controlled growing rods (MCGR) to treat patients with deformity in the growing spine to the conclusion of treatm ...
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Journal articleJournal of Clinical Medicine · October 1, 2021
Prognostic factors for clinical outcome after spinal cord (SC) injury (SCI) are limited but important in patient management and education. There is a lack of evidence regarding magnetic resonance imaging (MRI) and clinical outcomes in SCI patients. Therefo ...
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Journal articleEmerg Med J · September 2021
INTRODUCTION: Suspected septic arthritis is a common presentation to EDs. The underlying diagnosis is often non-infective pathology. Differentiating between aetiologies is difficult. A bedside test with high negative predictive value (NPV) may allow safe d ...
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Journal articleJ Pediatr Orthop · July 1, 2021
PURPOSE: The correction of severe, stiff scoliosis in children is challenging. One method used to reduce the risk is preoperative halo gravity traction (HGT). In this study, the authors sought to define the efficiency and safety of HGT and characterize the ...
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Journal articleSpine Deform · July 2021
PURPOSE: The three-rod technique, utilising a short apical concavity rod is an option to achieve controlled correction in severe scoliosis. We describe this technique, the complications encountered, and the long-term outcomes. METHOD: All paediatric patien ...
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Journal articleInt J Spine Surg · June 2021
BACKGROUND: The minimally invasive cortical trajectory screw (MidLF) technique has been described accompanied with posterolateral interbody fusion (PLIF). We present our 2-year results of a hybrid technique to show that using transforaminal interbody fusio ...
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Journal articleSpine Deform · May 2021
STUDY DESIGN: Case report. INTRODUCTION: Instrumented posterior fusion using pedicle screws has been the mainstay of the surgical correction of adolescent idiopathic scoliosis since it was popularised by Roy-Camille in the 1970s. The aim of this case repor ...
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Journal articleJ Pediatr Orthop · March 1, 2021
PURPOSE: Congenital kyphosis is a rare condition. In this case series we sought to identify the outcomes and complications of posterior instrumented fusion and the resultant epiphysiodesis effect in uniplanar congenital kyphosis in pediatric patients. METH ...
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Journal articleJ Pediatr Orthop · March 1, 2021
BACKGROUND: Controversy persists in the treatment of high-grade spondylolisthesis (HGS). Surgery is recommended in patients with intrusive symptoms and evidence debates the competing strategies. This study compares the radiologic outcomes and postoperative ...
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Journal articleSurgical Neurology International · January 1, 2021
Background: Gorham-Stout disease (GSD) is a rare syndrome presenting with progressive osteolysis which in the spine can lead to cord injury, instability, and deformity. Here, the early spine surgery may prevent catastrophic outcomes. Case Description: A 25 ...
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Journal articleEur Spine J · May 2020
PURPOSE: CT myelography has been used since 1976 to diagnose neural compression in the axial skeleton. With the advent of routine MRI, its role in accurately diagnosing neural compression has been questioned as its normal appearances are not defined in the ...
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Journal articleJournal of Orthopaedics · May 1, 2020
Introduction: This study aimed to determine the practicality and estimate the effect of administering pre-operative blood product resuscitation to a consecutive, prospectively recruited cohort of 100 patients admitted to a single centre with a hip fracture ...
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Journal articleCureus · June 10, 2019
OBJECTIVES: Surgeons require high-quality surgical instruments to carry out successful procedures. Poor quality instruments may break intraoperatively leading to a failed procedure or causing harm to the patient. By examining the National Reporting and Lea ...
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Journal articleCureus · December 2, 2018
The aim of this study was to determine the incidence of atypical femoral fractures in our local population, study their current outcomes and present a novel surgical strategy based on these data. Patients who received surgical fixation of an atypical patte ...
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Journal articleBMJ Open · May 4, 2017
UNLABELLED: To evaluate the evidence for the resuscitation of patients with hip fracture in the preoperative or perioperative phase of their treatment and its impact on mortality. DESIGN: We searched MEDLINE, EMBASE, CENTRAL and PROSPERO databases using a ...
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Journal articleBMJ Case Rep · January 25, 2017
Gluteal compartment syndrome is a rare entity, usually caused by direct trauma. This occurrence with sciatic nerve palsy caused by inferior gluteal artery laceration and compressive haematoma has not been reported in the literature. We describe such a case ...
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Journal articleWorld Journal of Orthopedics · January 1, 2016
Suicide as a cause of death, affects every health system, and is a particular problem in heavily urbanised states and low and middle income countries (which account for 75% of suicide deaths). The World Health Organisation records that 800000 commit suicid ...
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Journal articleAnn R Coll Surg Engl · March 2012
INTRODUCTION: Surgical fires are a rare but serious preventable safety risk in modern hospitals. Data from the US show that up to 650 surgical fires occur each year, with up to 5% causing death or serious harm. This study used the National Reporting and Le ...
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Journal articleBehaviour and Information Technology · July 1, 2011
In the UK, treatment recommendations for patients with cancer are all made within multi-disciplinary team (MDT) meetings. This has benefits, but it may delay treatment starting if MDT decisions require revision before implementation. This study examined wh ...
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Journal articleInjury · September 2009
INTRODUCTION: Numerous articles have examined the pattern of traumatic deaths. Most of these studies have aimed to improve trauma care and raise awareness of avoidable complications. The aim of the present review is to evaluate whether the distribution of ...
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