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Brian T Crouch

Assistant Research Professor in the Department of Biomedical Engineering
Biomedical Engineering
Room 1427 Fciemas, Box 90281, Durham, NC 27708
140 Science Drive, 373 Gross Hall, Durham, NC 27708

Overview


Dr. Crouch is an Assistant Research Professor in the Department of Biomedical Engineering and the Assistant Director of Research for the Center for Global Women's Health Technologies (GWHT). Dr. Crouch’s research interests intersect oncology, translational research, and global health, with a particular focus on diagnostics and therapeutics in low-resource settings. He is an expert in translating diagnostic technologies from the bench to bedside using in vitro cell culture and cell-based assays, small animal models, fluorescence microscopy, image processing, machine learning, and clinical trial design.

Current Appointments & Affiliations


Assistant Research Professor in the Department of Biomedical Engineering · 2020 - Present Biomedical Engineering, Pratt School of Engineering

In the News


Published January 22, 2025
From Philosophy to the U.S. Court of Appeals, Duke Authors Cover Big Topics

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Recent Publications


Impact of Injection-Based Delivery Parameters on Local Distribution Volume of Ethyl-Cellulose Ethanol Gel in Tissue and Tissue Mimicking Phantoms.

Journal Article IEEE transactions on bio-medical engineering · May 2024 ObjectiveLocal drug delivery aims to minimize systemic toxicity by preventing off-target effects; however, injection parameters influencing depot formation of injectable gels have yet to be thoroughly studied. We explored the effects of needle cha ... Full text Cite

Optical imaging reveals chemotherapy-induced metabolic reprogramming of residual disease and recurrence.

Journal Article Sci Adv · April 5, 2024 Fewer than 20% of triple-negative breast cancer patients experience long-term responses to mainstay chemotherapy. Resistant tumor subpopulations use alternative metabolic pathways to escape therapy, survive, and eventually recur. Here, we show in vivo, lon ... Full text Link to item Cite

Determining the Relationship between Delivery Parameters and Ablation Distribution for Novel Gel Ethanol Percutaneous Therapy in Ex Vivo Swine Liver.

Journal Article Polymers (Basel) · April 5, 2024 Ethyl cellulose-ethanol (ECE) is emerging as a promising formulation for ablative injections, with more controllable injection distributions than those from traditional liquid ethanol. This study evaluates the influence of salient injection parameters on f ... Full text Link to item Cite
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Recent Grants


A single shot therapy will accelerate the elimination of breast cancer

ResearchCollaborating Investigator · Awarded by United States Army Medical Research Acquisition Activity · 2024 - 2028

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Education, Training & Certifications


Duke University · 2018 Ph.D.