Overview
Dr. Crouch is an Assistant Research Professor in the Department of Biomedical Engineering and the Assistant Director of Research for the Center for Global Women's Health Technologies (GWHT). Dr. Crouch’s research interests intersect oncology, translational research, and global health, with a particular focus on diagnostics and therapeutics in low-resource settings. He is an expert in translating diagnostic technologies from the bench to bedside using in vitro cell culture and cell-based assays, small animal models, fluorescence microscopy, image processing, machine learning, and clinical trial design.
Current Appointments & Affiliations
Assistant Research Professor in the Department of Biomedical Engineering
·
2020 - Present
Biomedical Engineering,
Pratt School of Engineering
Recent Publications
Impact of Injection-Based Delivery Parameters on Local Distribution Volume of Ethyl-Cellulose Ethanol Gel in Tissue and Tissue Mimicking Phantoms.
Journal Article IEEE transactions on bio-medical engineering · May 2024 ObjectiveLocal drug delivery aims to minimize systemic toxicity by preventing off-target effects; however, injection parameters influencing depot formation of injectable gels have yet to be thoroughly studied. We explored the effects of needle cha ... Full text CiteOptical imaging reveals chemotherapy-induced metabolic reprogramming of residual disease and recurrence.
Journal Article Sci Adv · April 5, 2024 Fewer than 20% of triple-negative breast cancer patients experience long-term responses to mainstay chemotherapy. Resistant tumor subpopulations use alternative metabolic pathways to escape therapy, survive, and eventually recur. Here, we show in vivo, lon ... Full text Link to item CiteDetermining the Relationship between Delivery Parameters and Ablation Distribution for Novel Gel Ethanol Percutaneous Therapy in Ex Vivo Swine Liver.
Journal Article Polymers (Basel) · April 5, 2024 Ethyl cellulose-ethanol (ECE) is emerging as a promising formulation for ablative injections, with more controllable injection distributions than those from traditional liquid ethanol. This study evaluates the influence of salient injection parameters on f ... Full text Link to item CiteRecent Grants
A single shot therapy will accelerate the elimination of breast cancer
ResearchCollaborating Investigator · Awarded by United States Army Medical Research Acquisition Activity · 2024 - 2028View All Grants
Education, Training & Certifications
Duke University ·
2018
Ph.D.