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Brian T Crouch

Assistant Research Professor in the Department of Biomedical Engineering
Biomedical Engineering
Room 1427 FCIEMAS, Box 90281, Durham, NC 27708
140 Science Drive, 373 Gross Hall, Durham, NC 27708

Scholarly Works - Conferences


Optimizing fluorescently-tethered Hsp90 inhibitor dose for maximal specific uptake by breast tumors

Conference Progress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2018 Despite improvements in surgical resection, 20-40% of patients undergoing breast conserving surgery require at least one additional re-excision. Leveraging the unique surface expression of heat shock protein 90 (Hsp90), a chaperone protein involved in seve ... Full text Cite

Imaging of 2-NBDG and TMRE reveals glucose uptake and mitochondrial membrane potential in dorsal window chamber models

Conference Optics Infobase Conference Papers · January 1, 2017 For the first time, we performed simultaneous in vivo microscopic imaging of 2-NBDG and TMRE in a preclinical model, to successfully capture glucose and mitochondrial membrane potential on the same tissue site at one time. ... Full text Cite