Overview
Dr. Smith completed his residency in pediatrics and a fellowship in neonatal medicine at Duke University Medical Center in 2004 and 2007, respectively. He completed an MHS in clinical research from Duke University in 2006 and an MPH in biostatistics from the University of North Carolina at Chapel Hill in 2009. His research is focused on pediatric drug safety, neonatal pharmacology, and the epidemiology of neonatal infections. Dr. Smith is or has been the protocol chair for more than 14 studies of drugs in infants and children. He is the Principal Investigator for the Environmental Influences on Child Health Outcomes (ECHO) Coordinating Center.
Current Appointments & Affiliations
Samuel L. Katz Distinguished Professor of Pediatrics
·
2018 - Present
Pediatrics, Neonatology,
Pediatrics
Professor of Pediatrics
·
2015 - Present
Pediatrics, Neonatology,
Pediatrics
Member in the Duke Clinical Research Institute
·
2007 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Maternal Area of Residence and Outcomes for Mother-Infant Dyads with Perinatal Opioid Exposure.
Journal Article Am J Perinatol · February 2026 Determine the relationship between maternal Social Deprivation Index (SDI), a composite measure of area-level deprivation, and maternal characteristics and infant outcomes for mother-infant dyads with perinatal opioid exposure.Post hoc secondary analysis o ... Full text Link to item CiteAntenatal Exposure to Medication for Opioid Use Disorder and Infant Outcomes in the Eat, Sleep, Console for Neonatal Opioid Withdrawal Randomized Controlled Trial.
Journal Article J Pediatr · February 2026 OBJECTIVE: To evaluate associations between care approach (usual care vs Eat, Sleep, Console [ESC]) on infant outcomes, and how these associations were modified by medication (buprenorphine or methadone) for opioid use disorder (MOUD). STUDY DESIGN: A post ... Full text Link to item CiteAccelerated Weaning of Opioids to Reduce Pharmacologic Exposure for Neonatal Opioid Withdrawal Syndrome: A Randomized Clinical Trial.
Journal Article J Pediatr · January 17, 2026 OBJECTIVE: To determine if newborns receiving morphine or methadone as the primary pharmacologic treatment for neonatal opioid withdrawal syndrome (NOWS) tolerate and receive fewer days of opioid using an accelerated wean protocol (15% decrements) compared ... Full text Link to item CiteRecent Grants
Comparative Effectiveness of Emerging Medications in Children with Inflammatory Bowel Disease
ResearchCo Investigator · Awarded by University of North Carolina - Chapel Hill · 2025 - 2031iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 20302/3 CTSA K12 Program at Duke University
ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030View All Grants
Education
University of North Carolina, Chapel Hill ·
2009
M.P.H.
Duke University, School of Medicine ·
2006
M.H.S.
Mercer University ·
2001
M.D.