Overview
1. Genetic regulation of embryo development using the mouse as a research model.
2. The role of genes and signaling pathways in directing and co-ordinating the development of the lung.
3. The identity and regulation of the different stem cells in the adult lung and their role in repair, fibrosis and cancer.
2. The role of genes and signaling pathways in directing and co-ordinating the development of the lung.
3. The identity and regulation of the different stem cells in the adult lung and their role in repair, fibrosis and cancer.
Current Appointments & Affiliations
Research Professor of Cell Biology
·
2022 - Present
Cell Biology,
Basic Science Departments
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Publications
Bud, branch, breathe! Building a mammalian lung over space and time
Journal Article Developmental Biology · June 1, 2025 Many mammalian organs, such as the mammary and lachrymal glands, kidney and lungs develop by the process known as branching morphogenesis. An essential feature of this process is the reciprocal interaction between the inner branched tubular epithelium and ... Full text CiteCorrection: Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation.
Journal Article Development · August 6, 2024 Full text Link to item CiteDevelopment of the respiratory system
Chapter · January 1, 2024 Lung development requires the coordinated growth and morphogenesis of multiple cell populations: anterior foregut endoderm, splanchnic mesoderm, mesothelium, vasculature, lymphatics, immune cells and nerves. Together they give rise to the respiratory syste ... Full text CiteRecent Grants
Mechanism of epidermal coordination during development and regeneration in zebrafish
ResearchCollaborating Investigator · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2023 - 2028Training Program in Developmental and Stem Cell Biology
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2001 - 2027Dissecting input-output relationships of Developmental BMP Signaling
ResearchConsultant · Awarded by National Institutes of Health · 2024 - 2026View All Grants
Education, Training & Certifications
University of Cambridge (United Kingdom) ·
1968
Ph.D.