Scholars@Duke
Brian Eugene Brigman

Brian Eugene Brigman

Professor of Orthopaedic Surgery
Orthopaedic Surgery
brigm003@mc.duke.edu
Box 3312 Med Ctr, Durham, NC
1578 White Zone DS, Durham, NC

Scholarly Works - Conferences

Abstract 6642: Exploring the x-ray psoralen activated cancer therapy mechanism of action in a genetically engineered mouse model of soft tissue sarcoma

Conference Cancer Research · March 22, 2024 AbstractBACKGROUND: Psoralen is a natural ultraviolet activated compound that has been used for over 70 years to treat skin cancer, psoriasis, and vitiligo. Recently, to expand its use beyond external treatm ... Full text Cite

New Techniques for Diagnosis and Treatment of Musculoskeletal Tumors: Methods of Intraoperative Margin Detection

Conference Techniques in Orthopaedics · September 1, 2018 Although frozen section analysis remains the standard for intraoperative margin detection for some cancers, there are critical limitations with using this method in the treatment of musculoskeletal tumors. Extensive work has been done to develop more accur ... Full text Cite

Abstract SY36-03: Intraoperative molecular imaging with protease-activated fluorescent imaging agents

Conference Cancer Research · August 1, 2015 AbstractIntra-operative detection of residual cancer in the tumor bed can be used to decrease the risk of a positive surgical margin, reduce the rate of re-excision, and tailor adjuvant therapy. LUM015 is a ... Full text Cite