Current Appointments & Affiliations
Assistant Research Professor of Molecular Genetics and Microbiology
·
2019 - Present
Molecular Genetics and Microbiology,
Basic Science Departments
Member of the Duke Human Vaccine Institute
·
2024 - Present
Duke Human Vaccine Institute,
Institutes and Centers
Recent Publications
The coronavirus nsp14 exoribonuclease interface with the cofactor nsp10 is essential for efficient virus replication and enzymatic activity.
Journal Article J Virol · February 25, 2025 Coronaviruses (CoVs) encode non-structural proteins (nsp's) 1-16, which assemble to form replication-transcription complexes that function in viral RNA synthesis. All CoVs encode a proofreading 3'-5' exoribonuclease in non-structural protein 14 (nsp14-ExoN ... Full text Link to item CiteFluorescent and bioluminescent bovine H5N1 influenza viruses for evaluation of antiviral interventions.
Journal Article J Virol · November 19, 2024 In early 2024, a clade 2.3.4.4b high pathogenic H5N1 avian influenza virus was detected in dairy cows and humans in the United States. Since then, it has spread to herds in at least 13 states and caused symptomatic disease in at least fifteen people. To fa ... Full text Link to item CiteHeadless hemagglutinin-containing influenza viral particles direct immune responses toward more conserved epitopes.
Journal Article J Virol · October 22, 2024 Seasonal influenza vaccines provide mostly strain-specific protection due to the elicitation of antibody responses focused on evolutionarily plastic antigenic sites in the hemagglutinin head domain. To direct the humoral response toward more conserved epit ... Full text Link to item CiteRecent Grants
CIVICs A Option 22D
ResearchInvestigator · Awarded by National Institutes of Health · 2024 - 2026SRA - Neutralization capacity of purified anti-SARS-CoV-2 monoclonal antibodies
ResearchPrincipal Investigator · Awarded by Invivyd, Inc. · 2025 - 2026CIVICS Component A - Option 5
ResearchResearch Associate · Awarded by National Institutes of Health · 2019 - 2025View All Grants
Education, Training & Certifications
The University of Chicago ·
2012
Ph.D.