Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Resident, Medicine, Duke University 2004 - 2008
  • M.D., Washington University in St. Louis 2004
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Medicine, Medicine, General Internal Medicine, Medicine 2011 - 2020
  • Medical Instructor in the Department of Medicine, Medicine, General Internal Medicine, Medicine 2008 - 2011
• Research
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  External Relationships

  • Cohere Med Inc
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Rao, Vishal N., Evan Murray, Javed Butler, Lauren B. Cooper, Zachary L. Cox, Mona Fiuzat, Jennifer B. Green, et al. “In-Hospital Initiation of Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure With Reduced Ejection Fraction.” J Am Coll Cardiol 78, no. 20 (November 16, 2021): 2004–12. https://doi.org/10.1016/j.jacc.2021.08.064.
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    • Sendak, Mark P., Michael Gao, William Ratliff, Marshall Nichols, Armando Bedoya, Cara O’Brien, and Suresh Balu. “Looking for clinician involvement under the wrong lamp post: The need for collaboration measures.” J Am Med Inform Assoc 28, no. 11 (October 12, 2021): 2541–42. https://doi.org/10.1093/jamia/ocab129.
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    • Sandhu, Sahil, Anthony L. Lin, Nathan Brajer, Jessica Sperling, William Ratliff, Armando D. Bedoya, Suresh Balu, Cara O’Brien, and Mark P. Sendak. “Integrating a Machine Learning System Into Clinical Workflows: Qualitative Study.” J Med Internet Res 22, no. 11 (November 19, 2020): e22421. https://doi.org/10.2196/22421.
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    • Sendak, Mark P., William Ratliff, Dina Sarro, Elizabeth Alderton, Joseph Futoma, Michael Gao, Marshall Nichols, et al. “Real-World Integration of a Sepsis Deep Learning Technology Into Routine Clinical Care: Implementation Study.” Jmir Med Inform 8, no. 7 (July 15, 2020): e15182. https://doi.org/10.2196/15182.
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    • Bedoya, Armando D., Joseph Futoma, Meredith E. Clement, Kristin Corey, Nathan Brajer, Anthony Lin, Morgan G. Simons, et al. “Machine learning for early detection of sepsis: an internal and temporal validation study.” Jamia Open 3, no. 2 (July 2020): 252–60. https://doi.org/10.1093/jamiaopen/ooaa006.
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    • Rhee, Chanu, Travis M. Jones, Yasir Hamad, Anupam Pande, Jack Varon, Cara O’Brien, Deverick J. Anderson, et al. “Prevalence, Underlying Causes, and Preventability of Sepsis-Associated Mortality in US Acute Care Hospitals.” Jama Netw Open 2, no. 2 (February 1, 2019): e187571. https://doi.org/10.1001/jamanetworkopen.2018.7571.
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    • Bedoya, Armando D., Meredith E. Clement, Matthew Phelan, Rebecca C. Steorts, Cara O’Brien, and Benjamin A. Goldstein. “Minimal Impact of Implemented Early Warning Score and Best Practice Alert for Patient Deterioration.” Crit Care Med 47, no. 1 (January 2019): 49–55. https://doi.org/10.1097/CCM.0000000000003439.
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    • Rhee, Chanu, Michael R. Filbin, Anthony F. Massaro, Amy L. Bulger, Donna McEachern, Kathleen A. Tobin, Barrett T. Kitch, et al. “Compliance With the National SEP-1 Quality Measure and Association With Sepsis Outcomes: A Multicenter Retrospective Cohort Study.” Crit Care Med 46, no. 10 (October 2018): 1585–91. https://doi.org/10.1097/CCM.0000000000003261.
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    • Rhee, Chanu, Sarah R. Brown, Travis M. Jones, Cara O’Brien, Anupam Pande, Yasir Hamad, Amy L. Bulger, et al. “Variability in determining sepsis time zero and bundle compliance rates for the centers for medicare and medicaid services SEP-1 measure.” Infect Control Hosp Epidemiol 39, no. 8 (August 2018): 994–96. https://doi.org/10.1017/ice.2018.134.
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    • Perret-Guillaume, Christine, and Denis Wahl. “Cost-effectiveness of ximelagatran for stroke prevention.” Jama 293, no. 23 (June 15, 2005): 2860–61. https://doi.org/10.1001/jama.293.23.2860.
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    • “Cost-effectiveness of Ximelagatran for Stroke Prevention—Reply.” Jama 293, no. 23 (June 15, 2005): 2860–2860. https://doi.org/10.1001/jama.293.23.2861-a.
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    • O’Brien, Cara L., and Brian F. Gage. “Costs and effectiveness of ximelagatran for stroke prophylaxis in chronic atrial fibrillation.” Jama 293, no. 6 (February 9, 2005): 699–706. https://doi.org/10.1001/jama.293.6.699.
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    • Brendza, Robert P., Cara O’Brien, Kelly Simmons, Daniel W. McKeel, Kelly R. Bales, Steven M. Paul, John W. Olney, Joshua R. Sanes, and David M. Holtzman. “PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures.” J Comp Neurol 456, no. 4 (February 17, 2003): 375–83. https://doi.org/10.1002/cne.10536.
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    • Sandhu, Sahil, Anthony L. Lin, Nathan Brajer, Jessica Sperling, William Ratliff, Armando D. Bedoya, Suresh Balu, Cara O’Brien, and Mark P. Sendak. “Integrating a Machine Learning System Into Clinical Workflows: Qualitative Study (Preprint),” n.d. https://doi.org/10.2196/preprints.22421.
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  • Conference Papers

    • Sendak, M., M. C. Elish, M. Gao, J. Futoma, W. Ratliff, M. Nichols, A. Bedoya, S. Balu, and C. O’Brien. ““The human body is a black box”: Supporting clinical decision-making with deep learning.” In Fat* 2020  Proceedings of the 2020 Conference on Fairness, Accountability, and Transparency, 99–109, 2020. https://doi.org/10.1145/3351095.3372827.
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    • Boole, Lindsay, Jessica Seidelman, Aimee Zaas, George Cheely, Saumil Chudgar, Jeffrey Clarke, David Gallagher, et al. “Residents Finding Their Roots: Resident Workshops to Improve Patient Safety on the Wards while Teaching Residents Root Cause Analysis,” 2014.
       Open Access Copy
    • Chudgar, Saumil, William C. McManigle, Aubrey Jolly Graham, Jonathan Bae, Noppon P. Setji, and Cara L. O’Brien. “TEACHING ESSENTIAL SKILLS: TRAINING MEDICAL STUDENTS IN QUALITY IMPROVEMENT, PROCEDURES, AND TRANSITIONS OF CARE.” In Journal of General Internal Medicine, 28:S480–S480. SPRINGER, 2013.
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