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Carol Anne Colton

Professor in Neurology
Neurology, Translational Brain Sciences
Duke Box 2900, Durham, NC 27710
201H Bryan Res Bldg, Durham, NC 27710

Scholarly Works - Book sections


ApoE, Endotoxins, and Sepsis

Book section · January 1, 2026 Sepsis is a medical emergency caused by a dysregulated host response to bacterial and viral infections. Current investigations reveal that each host can have a different and potentially unique response to a particular pathogen. These complex responses are ... Full text Cite

Role of free radicals in alcohol-induced tissue injury

Book section · January 1, 2017 The role of reactive oxygen intermediates (ROI) and reactive nitrogen intermediates (RNI) in ethanol-induced toxicity has been supported by a variety of in vivo and in vitro studies. All tissues in the body are affected by exposure to ethanol, and variatio ... Full text Cite

Apolipoprotein E and Mimetics as Targets and Therapeutics for Alzheimer’s Disease

Book section · January 1, 2015 After age, the APOE4 genotype is the largest risk factor for Alzheimer’s disease (AD). We have developed a series of novel “COG” peptides that mimic the actions of full-length apolipoprotein-E3. Using multiple approaches, we show that COG1410 crosses the b ... Full text Cite