Carolyn Elizabeth Pizoli
Assistant Professor of Pediatrics
As the Director of Pediatric Neurocritical Care, my work focuses on applying the highest standard of treatments, neuroprotection and neurorehabilitation for children in the Neonatal, Pediatric and Pediatric Cardiac Intensive Care Units at Duke Children's Hospital.
Current Appointments & Affiliations
- Assistant Professor of Pediatrics, Pediatrics, Neurology, Pediatrics 2021
- Affiliate of the Center for Brain Imaging and Analysis, Duke-UNC Center for Brain Imaging and Analysis, Institutes and Centers 2011
Contact Information
- Background
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Education, Training, & Certifications
- Resident in Child Neurology, Neurology, St. Louis Children's Hospital 2006 - 2008
- Resident in Neurology, Neurology, Barnes-Jewish Hospital 2005 - 2006
- Pediatric Internship and Residency, Pediatrics, St. Louis Children's Hospital 2003 - 2005
- M.D., Pennsylvania State University 2003
- Ph.D., Pennsylvania State University 2003
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Previous Appointments & Affiliations
- Assistant Professor of Pediatrics, Pediatrics, Neurology, Pediatrics 2016 - 2020
- Assistant Professor of Pediatrics, Pediatrics, Neurology, Pediatrics 2010 - 2015
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Leadership & Clinical Positions at Duke
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Director, Pediatric Neurocritical Care
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Director, Pediatric Neurocritical Care
- Research
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Selected Grants
- Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in Infants awarded by National Institutes of Health 2018 - 2021
- Network Plasticity in Pediatric Traumatic Brain Injury- A Structural and Functional MRI Study of Network Plasticity in Pediatric Traumatic Brain Injury awarded by Child Neurology Foundation 2013 - 2014
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Harmon, Alexis, Cory Stingl, Aruna Rikhi, Linh Tran, Carolyn Pizoli, Michael Malinzak, and Heather Van Mater. “Pediatric GAD-65 Autoimmune Encephalitis: Assessing Clinical Characteristics and Response to Therapy With a Novel Assessment Scale.” Pediatr Neurol 128 (March 2022): 25–32. https://doi.org/10.1016/j.pediatrneurol.2021.12.007.Full Text Link to Item
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Mangalesh, Shwetha, Neeru Sarin, Brendan McGeehan, S Grace Prakalapakorn, Du Tran-Viet, C Michael Cotten, Sharon F. Freedman, Maureen G. Maguire, Cynthia A. Toth, and Cynthia A. BabySTEPS Group. “Preterm Infant Stress During Handheld Optical Coherence Tomography vs Binocular Indirect Ophthalmoscopy Examination for Retinopathy of Prematurity.” Jama Ophthalmol 139, no. 5 (May 1, 2021): 567–74. https://doi.org/10.1001/jamaophthalmol.2021.0377.Full Text Link to Item
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Cannon, Laura, Heather Van Mater, and Carolyn Pizoli. “Hypersomnolence in a 17-year-old Boy.” Pediatr Rev 42, no. Suppl 1 (January 2021): S82–84. https://doi.org/10.1542/pir.2019-0229.Full Text Link to Item
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Mangalesh, Shwetha, Du Tran-Viet, Carolyn Pizoli, Vincent Tai, Mays Antoine El-Dairi, Xi Chen, Christian Viehland, et al. “Subclinical Retinal versus Brain Findings in Infants with Hypoxic Ischemic Encephalopathy.” Graefes Arch Clin Exp Ophthalmol 258, no. 9 (September 2020): 2039–49. https://doi.org/10.1007/s00417-020-04738-0.Full Text Link to Item
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Trau, Steven P., and Carolyn E. Pizoli. “PURA Syndrome and Myotonia.” Pediatr Neurol 104 (March 2020): 62–63. https://doi.org/10.1016/j.pediatrneurol.2019.09.008.Full Text Link to Item
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Berube, Megan W., Monica E. Lemmon, Carolyn E. Pizoli, Margarita Bidegain, Veeral N. Tolia, C Michael Cotten, and Rachel G. Greenberg. “Opioid and benzodiazepine use during therapeutic hypothermia in encephalopathic neonates.” J Perinatol 40, no. 1 (January 2020): 79–88. https://doi.org/10.1038/s41372-019-0533-4.Full Text Link to Item
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Hansen, Adam W., Mullai Murugan, He Li, Michael M. Khayat, Liwen Wang, Jill Rosenfeld, B Kim Andrews, et al. “A Genocentric Approach to Discovery of Mendelian Disorders.” Am J Hum Genet 105, no. 5 (November 7, 2019): 974–86. https://doi.org/10.1016/j.ajhg.2019.09.027.Full Text Open Access Copy Link to Item
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Helbig, Katherine L., Robert J. Lauerer, Jacqueline C. Bahr, Ivana A. Souza, Candace T. Myers, Betül Uysal, Niklas Schwarz, et al. “De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias.” Am J Hum Genet 104, no. 3 (March 7, 2019): 562. https://doi.org/10.1016/j.ajhg.2019.02.015.Full Text Open Access Copy Link to Item
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Khan, Tahir N., Kamal Khan, Azita Sadeghpour, Hannah Reynolds, Yezmin Perilla, Marie T. McDonald, William B. Gallentine, et al. “Mutations in NCAPG2 Cause a Severe Neurodevelopmental Syndrome that Expands the Phenotypic Spectrum of Condensinopathies.” Am J Hum Genet 104, no. 1 (January 3, 2019): 94–111. https://doi.org/10.1016/j.ajhg.2018.11.017.Full Text Open Access Copy Link to Item
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Herrera, Tamara I., Laura Edwards, William F. Malcolm, P Brian Smith, Kimberley A. Fisher, Carolyn Pizoli, Kathryn E. Gustafson, et al. “Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy.” Early Hum Dev 125 (October 2018): 1–7. https://doi.org/10.1016/j.earlhumdev.2018.08.003.Full Text Link to Item
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Tan, Queenie K-G, Allyn McConkie-Rosell, Jane Juusola, Kathryn E. Gustafson, Carolyn E. Pizoli, Anne F. Buckley, and Yong-Hui Jiang. “The importance of managing the patient and not the gene: expanded phenotype of GLE1-associated arthrogryposis.” Cold Spring Harb Mol Case Stud 3, no. 6 (November 2017). https://doi.org/10.1101/mcs.a002063.Full Text Link to Item
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Pecoraro, Anthony, Eric Arehart, William Gallentine, Rodney Radtke, Edward Smith, Carolyn Pizoli, Sujay Kansagra, Elie Abdelnour, Roger McLendon, and Mohamad A. Mikati. “Epilepsy in neurofibromatosis type 1.” Epilepsy Behav 73 (August 2017): 137–41. https://doi.org/10.1016/j.yebeh.2017.05.011.Full Text Link to Item
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Edwards, Laura, Stephen DeMeo, Chi D. Hornik, C Michael Cotten, P Brian Smith, Carolyn Pizoli, Julie M. Hauer, and Margarita Bidegain. “Gabapentin Use in the Neonatal Intensive Care Unit.” J Pediatr 169 (February 2016): 310–12. https://doi.org/10.1016/j.jpeds.2015.10.013.Full Text Link to Item
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Rothman, Adam L., Monica B. Sevilla, Shwetha Mangalesh, Kathryn E. Gustafson, Laura Edwards, C Michael Cotten, Joshua S. Shimony, et al. “Thinner Retinal Nerve Fiber Layer in Very Preterm Versus Term Infants and Relationship to Brain Anatomy and Neurodevelopment.” Am J Ophthalmol 160, no. 6 (December 2015): 1296-1308.e2. https://doi.org/10.1016/j.ajo.2015.09.015.Full Text Link to Item
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Englander, Zoë A., Carolyn E. Pizoli, Anastasiya Batrachenko, Jessica Sun, Gordon Worley, Mohamad A. Mikati, Joanne Kurtzberg, and Allen W. Song. “Diffuse reduction of white matter connectivity in cerebral palsy with specific vulnerability of long range fiber tracts.” Neuroimage Clin 2 (2013): 440–47. https://doi.org/10.1016/j.nicl.2013.03.006.Full Text Open Access Copy Link to Item
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Raike, Robert S., Carolyn E. Pizoli, Catherine Weisz, Arn M. J. M. van den Maagdenberg, H. A. Jinnah, and Ellen J. Hess. “Limited regional cerebellar dysfunction induces focal dystonia in mice.” Neurobiol Dis 49 (January 2013): 200–210. https://doi.org/10.1016/j.nbd.2012.07.019.Full Text Link to Item
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Pizoli, Carolyn E., Manish N. Shah, Abraham Z. Snyder, Joshua S. Shimony, David D. Limbrick, Marcus E. Raichle, Bradley L. Schlaggar, and Matthew D. Smyth. “Resting-state activity in development and maintenance of normal brain function.” Proc Natl Acad Sci U S A 108, no. 28 (July 12, 2011): 11638–43. https://doi.org/10.1073/pnas.1109144108.Full Text Link to Item
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Pizoli, Carolyn E., H. A. Jinnah, Melvin L. Billingsley, and Ellen J. Hess. “Abnormal cerebellar signaling induces dystonia in mice.” J Neurosci 22, no. 17 (September 1, 2002): 7825–33. https://doi.org/10.1523/JNEUROSCI.22-17-07825.2002.Full Text Link to Item
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