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Patrick John Casey

James B. Duke Distinguished Professor of Pharmacology and Cancer Biology
Pharmacology & Cancer Biology
Duke Box 3813, Durham, NC 27710
450 Research Drive, C334 Lev Sci Res Ctr, Durham, NC 27708

Scholarly Works - Book sections


Targeting RAS membrane association

Book section · January 1, 2024 RAS proteins are synthesized as globular hydrophilic proteins that are secondarily targeted to cellular membranes by a series of C-terminal posttranslational modifications. These include prenylation, endoproteolysis, and carboxymethylation of a C-terminal ... Full text Cite

Signaling Through Gz

Book section · January 1, 2009 Several studies have been carried out to pinpoint specific brain regions and developmental stages where Gz is transcribed or expressed. The limited tissue distribution of Gαz, its unusual biochemical properties, the identification of Gαz-specific effectors ... Full text Cite

Signaling through Gz

Book section · January 1, 2003 Full text Cite