Chad Aaron Grotegut
Associate Professor of Obstetrics and Gynecology

I am a specialist in maternal-fetal medicine, which is a subspecialty of OB/GYN that focuses on the care of women with high-risk pregnancies.  I serve as the Medical Director of the Labor and Delivery Unit at Duke University Hospital.  In that role, and together with our outstanding unit team members, we have the opportunity to help women and their families ensure that they have the safest and best labor and delivery experience possible.  My specific clinical interests are in placenta accreta spectrum and other obstetric, medical, or surgical conditions that potentially could complicate a woman’s delivery.  

I conduct both basic science/laboratory research, as well as participate in running clinical studies. My laboratory research interests primarily focus on the hormone oxytocin and in understanding the mechanisms of uterine contractility.  This work is translated then to the clinical care of women through studies dedicated to understanding normal and abnormal labor; where abnormal labor increases a woman's risk for needing a cesarean delivery.  In addition to our work in labor, our group is involved in understanding the role that medical conditions and complications have in pregnancy outcomes, particularly related to abnormal placentation as in placenta accreta spectrum.

Current Research Interests

  • Molecular mechanisms regulating oxytocin receptor desensitization and labor outcomes (basic and translational)
  • Role of STIM1 in term labor (basic and translational)
  • Placenta accreta spectrum
  • Clinical trials in labor management, tocolysis, and preeclampsia prevention (clinical trials)
  • Epidemiology of postpartum hemorrhage and labor abnormalities (epidemiology and clinical trials)
  • Medical complications of pregnancy (epidemiology)

Current Appointments & Affiliations

Contact Information

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