Chang Yong Chung
Professor of Biology at Duke Kunshan University

Current Research Interests

Inflammation is a crucial component of the pathophysiology of both acute injuries and chronic neurological diseases, including Parkinson’s and Alzheimer’s. Inflammation in neuronal injuries and neurodegeneration involves important roles for resident inflammatory cells known as microglia. Microglia activation/chemotaxis is a prerequisite for microglia function, whether it is neuroprotective or inflammatory. Therefore, understanding microglial activation/chemotaxis is essential for designing rational approaches for therapeutic modulation of this response, and a better understanding of the regulation of microglia proliferation and chemotaxis has important therapeutic implications. However, it is not fully understood how the activation and chemotaxis of resident microglia in the brain is controlled at early stage of neuroinflammation. We have undertaken the responsibility of unraveling complex networks of signaling pathways controlling microglia activation/chemotaxis. We are also expanding our efforts to find an effective way to inhibit the directed cell migration during tumor metastasis.

Current Appointments & Affiliations

Contact Information

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