Skip to main content
construction release_alert
Profile editing is temporarily unavailable from June 11-24, 2026 while manual profile data entry transitions to Elements. Learn More.
cancel

Chao-Chieh Lin

Research Associate, Senior
Molecular Genetics and Microbiology

Current Appointments & Affiliations


Recent Publications


MESH1-mediated coenzyme A degradation drives ferroptosis sensitivity and muscle pathology.

Journal Article J Clin Invest · June 1, 2026 CoA facilitates fatty acid synthesis, energy production, gene regulation, and antioxidant function. While CoA biosynthesis is well characterized, the mechanisms governing CoA degradation remain poorly understood. Here, we identify the Metazoan Homolog of S ... Full text Open Access Link to item Cite

Ascites protects against ferroptosis and enables the peritoneal growth of ovarian cancer.

Journal Article Nat Commun · May 11, 2026 The peritoneum is a frequent site of metastasis in ovarian cancer (OVCA), often accompanied by the accumulation of ascites in the peritoneal cavity. Despite its prevalence, ascites and its role in the peritoneal growth of OVCA remain poorly understood. OVC ... Full text Link to item Cite

MESH1 functions as a metazoan PAPS phosphatase to regulate sulfation.

Journal Article Nat Chem Biol · April 10, 2026 Biological sulfation reactions require 3'-phosphoadenosine-5'-phosphosulfate (PAPS) as the universal sulfate donor. While the biosynthetic pathway of PAPS has been well characterized, the phosphatase degrading PAPS remains unidentified. Here, we discover M ... Full text Open Access Link to item Cite
View All Publications

Recent Grants


The role of ferroptosis in the metastatic ovarian cancer

ResearchPost Doctoral Trainee · Awarded by Ovarian Cancer Research Alliance · 2022 - 2025

Metabolic regulation of KLHL proteins through glycosylation

ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2019 - 2024

Gene expression programs of lactic acidosis in human cancers

ResearchGraduate Student · Awarded by National Institutes of Health · 2007 - 2018

View All Grants