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Chao-Chieh Lin

Research Associate, Senior
Molecular Genetics and Microbiology

Research Interests


I joined UPGG program in 2011. I am currently in Dr. Ashley Chi’s lab and investigate whether cellular metabolism can affect mitotic fidelity. We found that CoA depletion can trigger a series of events to lead to multi-nucleation in cancer cells. I am trying to map the pathways and mechanisms leading to the phenotype. Before coming to Duke, I received a B.A. and M.S. degree in genetics and genomics at National Yang-Ming University in Taiwan. I worked on the molecular mechanism of genetic variations on the susceptibility of uremia. After graduation, I worked at Academia Sinica in Taiwan, focusing on the ion channels which can change mouse behavior.

Selected Grants


The role of ferroptosis in the metastatic ovarian cancer

ResearchPost Doctoral Trainee · Awarded by Ovarian Cancer Research Alliance · 2022 - 2024

Metabolic regulation of KLHL proteins through glycosylation

ResearchPostdoctoral Associate · Awarded by National Institutes of Health · 2019 - 2024

Gene expression programs of lactic acidosis in human cancers

ResearchGraduate Student · Awarded by National Institutes of Health · 2007 - 2018