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Chin-Ho Chen

Professor Emeritus in Surgery
Surgery, Surgical Sciences
Box 2926 Med Ctr, Durham, NC 27710
SORF Bldg Room 117. South LaSalle St., Durham, NC 27710

Current Appointments & Affiliations


Professor Emeritus in Surgery · 2024 - Present Surgery, Surgical Sciences, Surgery
Member of the Duke Cancer Institute · 2003 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


Anti-HIV diterpenoids from Daphne pseudomezereum.

Journal Article Phytochemistry · April 2025 The plants of the genus Daphne (Thymelaeaceae) are known to be sources of anti-HIV diterpenoids. Therefore, the present study focused on investigating the anti-HIV diterpenoids in Daphne pseudomezereum, for which the isolation of diterpenoids has not been ... Full text Link to item Cite

Identification of anti-HIV cycloartane triterpenoids from Actaea vaginata using UPLC‐QTOF‐MS/MS, DFT calculations, docking, and molecular dynamics studies

Journal Article Journal of Molecular Structure · February 15, 2025 Structurally diverse triterpenoids have shown potential as pharmaceutical precursors for HIV treatment. Our previous research led to the discovery of a potent antiviral cycloartane triterpenoid derivative, (20S,24S)-15β,16β-diacetoxy-18,24;20,24-diepoxy-9, ... Full text Cite

Recent progress on triterpenoid derivatives and their anticancer potential.

Journal Article Phytochemistry · January 2025 Cancer poses a significant global public health challenge, with commonly used adjuvant or neoadjuvant chemotherapy often leading to adverse side effects and drug resistance. Therefore, advancing cancer treatment necessitates the ongoing development of nove ... Full text Link to item Cite
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Recent Grants


New Non-Nuceleotide Reverse Transcriptase Inhibitors for Drug Resistant HIV Strains

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2024

Small Molecule HIV-1 Entry Inhibitor with Novel Mechanisms of Action

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2021

Aloperine derivatives as novel anti-influenza agents

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2020 - 2021

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Education, Training & Certifications


University of North Carolina, Chapel Hill · 1991 Ph.D.