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Christopher Wildrick Woods

Wolfgang Joklik Distinguished Professor of Global Health
Medicine, Infectious Diseases
310 Trent Drive, Duke Box #90519, Durham, NC 27708

Featured Works


Assessment of Clostridium difficile-associated disease surveillance definitions, North Carolina, 2005.

Journal article Infect Control Hosp Epidemiol · March 2008 Featured Publication OBJECTIVE: To determine the timing of community-onset Clostridium difficile-associated disease (CDAD) relative to the patient's last healthcare facility discharge, the association of postdischarge cases with healthcare facility-onset cases, and the influen ... Full text Link to item Cite

Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study.

Journal article Infect Control Hosp Epidemiol · August 2007 Featured Publication BACKGROUND: The Burkholderia cepacia complex is associated with colonization or disease in patients with cystic fibrosis (CF). For patients without CF, this complex is poorly understood apart from its presence in occasional point source outbreaks. OBJECTIV ... Full text Link to item Cite

Bartonella species in blood of immunocompetent persons with animal and arthropod contact.

Journal article Emerg Infect Dis · June 2007 Featured Publication Using PCR in conjunction with pre-enrichment culture, we detected Bartonella henselae and B. vinsonii subspecies berkhoffii in the blood of 14 immunocompetent persons who had frequent animal contact and arthropod exposure. ... Full text Link to item Cite

Controlled clinical comparison of BacT/ALERT standard aerobic and standard anaerobic blood culture bottles inoculated directly or after transport in sodium polyanethol sulfonate tubes.

Journal article J Clin Microbiol · April 2007 Featured Publication To assess relative performances in the BacT/ALERT blood culture system, we compared results from the direct inoculation of standard media and inoculation after the transport of blood samples in Vacutainer tubes with sodium polyanethol sulfonate. No signifi ... Full text Link to item Cite

Emergence of Salmonella enterica serotype Paratyphi A as a major cause of enteric fever in Kathmandu, Nepal.

Journal article Trans R Soc Trop Med Hyg · November 2006 Featured Publication We performed pulsed-field gel electrophoresis (XbaI) on 114 bloodstream isolates of Salmonella enterica serotype Paratyphi A and S. enterica serotype Typhi collected from febrile patients in Kathmandu, Nepal. Of the 56 S. Paratyphi A isolates, 51 (91%) wer ... Full text Link to item Cite

Increased case-fatality rate associated with outbreaks of Neisseria meningitidis infection, compared with sporadic meningococcal disease, in the United States, 1994-2002.

Journal article Clin Infect Dis · July 1, 2006 Featured Publication BACKGROUND: Outbreaks of meningococcal disease are infrequent but important public health events. We characterize outbreak-associated cases in the United States and compare them with sporadic disease. METHODS: Outbreaks of meningococcal disease that occurr ... Full text Link to item Cite

Clinical features of scrub typhus.

Journal article Clin Infect Dis · May 15, 2006 Featured Publication Full text Link to item Cite

Use of sentinel laboratories by clinicians to evaluate potential bioterrorism and emerging infections.

Journal article Clin Infect Dis · May 1, 2006 Featured Publication With the persistent threat of emerging infectious diseases and bioterrorism, it has become increasingly important that clinicians be able to identify the diseases that might signal the occurrence of these unusual events. Essential to a thoughtful diagnosti ... Full text Link to item Cite

West Nile virus among hospitalized, febrile patients: a case for expanding diagnostic testing.

Journal article Vector Borne Zoonotic Dis · 2006 Featured Publication In Georgia, most individuals reported with West Nile virus (WNV) disease have been diagnosed with West Nile neuroinvasive disease (WNND). Relatively few cases of West Nile Fever (WNF) are reported, and the burden of illness due to WNV is likely underestima ... Full text Link to item Cite

Repeat infective endocarditis: differentiating relapse from reinfection.

Journal article Clin Infect Dis · August 1, 2005 Featured Publication Repeat infective endocarditis due to the same species can represent relapse of the initial infection or a new infection. We used time-based clinical criteria and pulsed-field gel electrophoresis-based molecular criteria to classify 13 cases of repeat infec ... Full text Link to item Cite

A man with chest pain and glomerulonephritis.

Journal article Lancet · June 11, 2005 Featured Publication Full text Link to item Cite

Streptococcus pneumoniae antigen test using positive blood culture bottles as an alternative method to diagnose pneumococcal bacteremia.

Journal article J Clin Microbiol · May 2005 Featured Publication Recovery of Streptococcus pneumoniae from positive blood culture bottles may be difficult due to autolysis of pneumococci. Therefore, we evaluated the performance of the Binax NOW S. pneumoniae antigen test with samples from positive blood culture bottles ... Full text Link to item Cite

Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia.

Journal article Clin Infect Dis · March 1, 2005 Featured Publication BACKGROUND: The role of both host and pathogen characteristics in hematogenous seeding following Staphylococcus aureus bacteremia is incompletely understood. METHODS: Consecutive patients with intravascular catheter-associated Staphylococcus aureus bactere ... Full text Link to item Cite

Antibacterial susceptibility testing in the clinical laboratory.

Journal article Infect Dis Clin North Am · September 2004 Featured Publication This article familiarizes the clinician with the principles of bacterial susceptibility testing and reporting to facilitate communication with the clinical microbiology laboratory. The emergence of resistance in nearly all commonly isolated bacterial organ ... Full text Link to item Cite

The etiology of febrile illness in adults presenting to Patan hospital in Kathmandu, Nepal.

Journal article Am J Trop Med Hyg · June 2004 Featured Publication In Nepal, many infections remain poorly characterized, partly due to limited diagnostic facilities. We studied consecutive febrile adults presenting to a general hospital in Kathmandu, Nepal. Of the 876 patients enrolled, enteric fever and pneumonia were t ... Link to item Cite

Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia.

Journal article Clin Infect Dis · May 1, 2004 Featured Publication The Burkholderia cepacia complex includes 9 genomovars. The relative virulence of each is unknown. Host and pathogen features associated with mortality were evaluated among patients with B. cepacia complex bacteremia. Cases were ascertained through review ... Full text Link to item Cite

Evaluation of four commercially available rapid serologic tests for diagnosis of leptospirosis.

Journal article J Clin Microbiol · February 2003 Featured Publication Four rapid tests for the serologic diagnosis of leptospirosis were evaluated, and the performance of each was compared with that of the current standard, the microscopic agglutination test (MAT). The four rapid tests were a microplate immunoglobulin M (IgM ... Full text Link to item Cite

Outbreak of leptospirosis among triathlon participants and community residents in Springfield, Illinois, 1998.

Journal article Clin Infect Dis · June 15, 2002 Featured Publication We investigated an outbreak of leptospirosis among athletes and community residents after a triathlon was held in Springfield, Illinois. A telephone survey was conducted to collect clinical information and data on possible risk factors, community surveilla ... Full text Link to item Cite

Surveillance for unexplained deaths and critical illnesses due to possibly infectious causes, United States, 1995-1998.

Journal article Emerg Infect Dis · February 2002 Featured Publication Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the in ... Full text Link to item Cite

An outbreak of Rift Valley fever in Northeastern Kenya, 1997-98.

Journal article Emerg Infect Dis · February 2002 Featured Publication In December 1997, 170 hemorrhagic fever-associated deaths were reported in Garissa District, Kenya. Laboratory testing identified evidence of acute Rift Valley fever virus (RVFV). Of the 171 persons enrolled in a cross-sectional study, 31(18%) were anti-RV ... Full text Link to item Cite

Changing patient characteristics and the effect on mortality in endocarditis.

Journal article Arch Intern Med · January 14, 2002 Featured Publication BACKGROUND: Limited data exist on recent demographic and microbiological changes in infective endocarditis (IE) and the impact of these changes on patient survival. METHODS: Data were collected from all patients with definite or possible IE at Duke Univers ... Full text Link to item Cite

Coccidioidomycosis in human immunodeficiency virus-infected persons in Arizona, 1994-1997: incidence, risk factors, and prevention.

Journal article J Infect Dis · April 2000 Featured Publication From 1 January 1995 through 31 June 1997, 153 cases of coccidioidomycosis in human immunodeficiency virus (HIV)-infected persons were identified in Arizona (incidence, 41/1000 persons living with AIDS). A case-control study was conducted to evaluate risk f ... Full text Link to item Cite

Emergency vaccination against epidemic meningitis in Ghana: implications for the control of meningococcal disease in West Africa.

Journal article Lancet · January 1, 2000 Featured Publication BACKGROUND: Recurrent epidemics of meningococcal disease have been reported throughout the African meningitis belt since description of the disease in 1912. Meningooccal polysaccharide vaccines can effectively prevent disease but the optimum strategy for t ... Full text Link to item Cite