Current Appointments & Affiliations
Butler Harris Assistant Professor in Radiation Oncology
·
2023 - Present
Radiation Oncology,
Clinical Science Departments
Assistant Professor of Radiation Oncology
·
2023 - Present
Radiation Oncology,
Clinical Science Departments
Member of the Duke Cancer Institute
·
2020 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Rewiring cancer: 3D genome determinants of cancer hallmarks.
Journal Article Curr Opin Genet Dev · April 2025 In modern cancer biology, Hanahan and Weinberg's classic depiction of the Hallmarks of Cancer serves as a heuristic for understanding malignant phenotypes [1]. Genetic determinants of these phenotypes promote cancer induction and progression, and these mut ... Full text Link to item CiteCirculating Tumor DNA Predicts Pathologic and Clinical Outcomes Following Neoadjuvant Chemoradiation and Surgery for Patients With Locally Advanced Rectal Cancer.
Journal Article JCO Precis Oncol · 2021 PURPOSE: This study was designed to assess the ability of perioperative circulating tumor DNA (ctDNA) to predict surgical outcome and recurrence following neoadjuvant chemoradiation for locally advanced rectal cancer (LARC). MATERIALS AND METHODS: Twenty-n ... Full text Link to item CiteDistribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions.
Journal Article Cell Death Dis · September 1, 2011 Malignant gliomas contain a population of self-renewing tumorigenic stem-like cells; however, it remains unclear how these glioma stem cells (GSCs) self-renew or generate cellular diversity at the single-cell level. Asymmetric cell division is a proposed m ... Full text Link to item CiteRecent Grants
Harnessing treatment-induced tumor evolution and collateral sensitivities using a human rectal cancer co-clinical platform
ResearchPrincipal Investigator · Awarded by National Cancer Institute · 2022 - 2027Epigenetic mechanisms of intestinal stem cell fate conversion in response to severe radiation injury
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2025 - 2027Deciphering Epigenetic Drivers of Concerted Cell Fate Changes in Rectal Cancer Radiation Response
ResearchPrincipal Investigator · Awarded by V Foundation for Cancer Research · 2024 - 2027View All Grants
Education, Training & Certifications
Duke University ·
2012
M.D.
Duke University ·
2010
Ph.D.
Duke University ·
2004
B.S.