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Christoph Paul Vincent Hornik

Samuel L. Katz Distinguished Professor of Pediatrics
Pediatrics, Critical Care Medicine
DCRI PO Box 17969, Durham, NC 27715
Dept of Pediatrics, Durham, NC 27710

Current Appointments & Affiliations


Samuel L. Katz Distinguished Professor of Pediatrics · 2024 - Present Pediatrics, Critical Care Medicine, Pediatrics
Professor of Pediatrics · 2023 - Present Pediatrics, Critical Care Medicine, Pediatrics
Chief, Division of Quantitative Sciences · 2018 - Present Pediatrics, Clinical Science Departments
Vice-Chair for Research in the Department of Pediatrics · 2022 - Present Pediatrics, Clinical Science Departments
Membership in the Duke Clinical Research Institute · 2013 - Present Duke Clinical Research Institute, Institutes and Centers

In the News


Published July 3, 2025
Better Health for Teens Starts with Going Places in the Neighborhood
Published March 19, 2024
Duke Awards 32 New Distinguished Professorships for 2024
Published October 7, 2022
New DCRI Center Targets Ending Opioid Addiction

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Recent Publications


Supervised Fine-Tuning of Large Language Models With Chain-of-Thought Reasoning for Pediatric Heart Disease Detection in Unstructured Echocardiogram Reports: Algorithm Development and Validation

Journal Article JMIR Formative Research · June 8, 2026 AbstractBackgroundPediatric heart disease (PHD), including congenital heart defects, is often incompletel ... Full text Cite

Safety of Sildenafil in Premature Infants with Severe Bronchopulmonary Dysplasia (SILDI-SAFE): A Randomized Controlled Trial.

Journal Article J Pediatr · May 7, 2026 OBJECTIVE: To describe the safety of sildenafil based on hypotension in premature infants with bronchopulmonary dysplasia (BPD). STUDY DESIGN: We conducted a multicenter, randomized, double-blind, placebo-controlled, dose-escalating trial of sildenafil. In ... Full text Link to item Cite

Obesity Pharmacotherapy: An Urgent Need for Progressing Science, Access, and Equity-JACC: Advances Expert Panel.

Journal Article JACC Adv · May 2026 The Duke Clinical Research Institute hosted a think tank, "Anti-Obesity Pharmacotherapy: Need for Guidance, Access, and Equity" in October 2024. This brought together multi-industry stakeholders to align and advance the field of obesity medications (OMs). ... Full text Link to item Cite
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Recent Grants


INNOVATE (Integrated National Network for Obstetric and Pediatric AdVAncement in Therapeutic Education)

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2026 - 2031

iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 2030

2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030

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Education


University of North Carolina, Chapel Hill · 2019 Ph.D.
University of North Carolina, Chapel Hill · 2012 M.P.H.
Albert Ludwigs University of Freiburg (Germany) · 2005 M.D.