Christoph Paul Vincent Hornik

Christoph Paul Vincent Hornik
Associate Professor of Pediatrics

Current Appointments & Affiliations

Associate Professor of Pediatrics, Pediatrics, Critical Care Medicine, Pediatrics 2017
Chief, Division of Quantitative Sciences, Pediatrics, Neonatology, Pediatrics 2018
Membership in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2013

Contact Information

DCRI PO Box 17969, Durham, NC 27715
Dept of Pediatrics, Durham, NC 27710
christoph.hornik@duke.edu (919) 684-8111

Background
Education, Training, & Certifications
- Ph.D., University of North Carolina at Chapel Hill 2019
- Pediatric Cardiology and Critical Care Medicine Fellowship, Pediatrics, Duke University School of Medicine 2008 - 2013
- M.P.H., University of North Carolina at Chapel Hill 2012
- Pediatric Internship and Residency, Pediatrics, Duke University School of Medicine 2005 - 2008
- M.D., Albert Ludwigs University of Freiburg (Germany) 2005
Duke Appointment History
- Assistant Professor of Pediatrics, Pediatrics, Critical Care Medicine, Pediatrics 2013 - 2017
Recognition
In the News
- MAR 10, 2020 DCRI Pulse Website
  
  New DCRI Registry Could Provide Path for Pediatric Migraine Drug Development
Research
Selected Grants
- A Phase 1 Study of AAV8-LSPhGAA (ACTUS-101) in Late-Onset Pompe Disease 2018 - 2024
- Overcoming barriers to addressing childhood opioid exposure: Developing Standard Clinical Outcome Assessments for Pediatric Trials of Opioid-Sparing Drugs for Acute Pain awarded by Food and Drug Administration 2019 - 2024
- Real World Data to Support Pediatric Drug Labeling awarded by Burroughs Wellcome Fund 2019 - 2024
- Duke Summer Training in Academic Research (Duke's STAR) awarded by National Institutes of Health 2018 - 2023
- PTN2- TO# BPCA Pharmacology Studies 2018 - 2022
- Global Pediatric Clinical Trials Network awarded by Food and Drug Administration 2017 - 2022
- Pharmacokinetics, Pharmacodynamics, and Safety of Methylprednisolone in Neonates on Cardiopulmonary Bypass awarded by National Institutes of Health 2017 - 2022
- Perioperative Tissue Penetration of Antimicrobials in Infants 2020 - 2021
- Bridging the Gap to Enhance Clinical Research Program (BIGGER) awarded by National Institutes of Health 2016 - 2021
- Safety of Sildenafil in Premature Infants with Severe Bronchopulmonary Dysplasia awarded by National Institutes of Health 2019 - 2021
- PTN 2.0 TO 1 Core Function Activities_Option 2 2020 - 2021
- PMR 292932: A Nationally Representative Drug Utilization Study of OxyContin in Children Aged 17 Years and Younger 2018 - 2021
- Pediatric Critical Care Research Landscape - A National Expert Conference awarded by National Institutes of Health 2020 - 2021
- R21 ICT Tools for Rare Diseases 2019 - 2020
- PTN2- TO# 3 Concept Development and Clinical Trial Readiness Support Option Period 1 2019 - 2020
- Safety of Sildenafil in Premature Infants at Risk of Bronchopulmonary Dysplasia awarded by University of North Carolina - Chapel Hill 2018 - 2020
- A Phase I Study of the Safety of AAV2/8 LSPhGAA in Late-onset Pompe Disease awarded by National Institutes of Health 2017 - 2020
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2016 - 2020
- Pediatric Trials Network_ Task Order 1_ Core Function Activities Option Period 1 2019 - 2020
- PTN2- TO# BPCA Concept Development and Clinical Trial Readiness Support 2018 - 2019
- UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program awarded by University of North Carolina - Chapel Hill 2017 - 2019
- Pediatric Trials Network_ Task Order 1_ Core Function Activities 2018 - 2019
- Echocardiogram to Diagnose Pulmonary Hypertension in Premature Infants awarded by University of North Carolina - Chapel Hill 2015 - 2019
- SOLI - Solithromycin Pediatric Development Program (Phase 2/3)- Labor & Sub Cost 2016 - 2018
- PTN Task Order 36- PTN Repository: Modification 1 awarded by National Institutes of Health 2016 - 2018
- PTN TO #39: PPE awarded by National Institutes of Health 2015 - 2018
- PTN TO #34: Program Management Support - Option 2 2017 - 2018
- Duke CTSA (UL1) awarded by National Institutes of Health 2013 - 2018
- PTN TO#47 (Protocol Development V) 2017 - 2018
- Linking Safety Practices to Adverse Events and Outcomes in Hospitalized Infants awarded by National Institutes of Health 2015 - 2018
- PTN TO#36 - PTN Repository 2015 - 2017
- PTN TO#40 (Protocol Development IV) 2015 - 2016
- CISA TO2 Prophylactic Antipyretics Revision 1-A 2014 - 2016
- CISA TO2 Prophylactic Antipyretics Revision 3-A 2014 - 2016
- CISA TO2 Prophylactic Antipyretics 2013 - 2016
- PTN Task Order--Protocol Development III awarded by National Institutes of Health 2014 - 2015
External Relationships
- Anavex Pharmaceuticals
- Purdue Pharma L.P.
- Sarfez Pharmaceuticals
- UCB Pharma
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Pek, Jen Heng, Bei Jun Yap, Ming Ying Gan, Shu Ting Tammie Seethor, Rachel Greenberg, Christoph Paul Vincent Hornik, Bobby Tan, Jan Hau Lee, and Shu-Ling Chong. “Neurocognitive impairment after neonatal sepsis: protocol for a systematic review and meta-analysis.” Bmj Open 10, no. 6 (June 11, 2020): e038816. https://doi.org/10.1136/bmjopen-2020-038816.
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  - Donoghue, Aaron J., Maybelle Kou, Grace L. Good, Carmel Eiger, Mark Nash, Fred M. Henretig, Helen Stacks, et al. “Impact of Personal Protective Equipment on Pediatric Cardiopulmonary Resuscitation Performance: A Controlled Trial.” Pediatr Emerg Care 36, no. 6 (June 2020): 267–73. https://doi.org/10.1097/PEC.0000000000002109.
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  - Maharaj, Anil R., Huali Wu, Christoph P. Hornik, Antonio Arrieta, Laura James, Varsha Bhatt-Mehta, John Bradley, et al. “Use of normalized prediction distribution errors for assessing population physiologically-based pharmacokinetic model adequacy.” J Pharmacokinet Pharmacodyn 47, no. 3 (June 2020): 199–218. https://doi.org/10.1007/s10928-020-09684-2.
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  - Seltzer, Jonathan H., Ann Farrell, Neil Goldenberg, Christoph Hornik, Daniel Keene, Mitchell W. Krucoff, Concetta Lipardi, et al. “Defining the path ahead for NOAC use in the pediatric population: A Cardiac Safety Research Consortium Think Tank.” Am Heart J 224 (June 2020): 138–47. https://doi.org/10.1016/j.ahj.2020.02.012.
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  - Hornik, Christoph P. “Commentary: Outcomes of truncus arteriosus repair: Insights from time and numbers.” J Thorac Cardiovasc Surg, May 23, 2020. https://doi.org/10.1016/j.jtcvs.2020.05.025.
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  - Ge, Shufan, Susan R. Mendley, Jacqueline G. Gerhart, Chiara Melloni, Christoph P. Hornik, Janice E. Sullivan, Andrew Atz, et al. “Population Pharmacokinetics of Metoclopramide in Infants, Children, and Adolescents.” Clin Transl Sci, April 23, 2020. https://doi.org/10.1111/cts.12803.
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  - Drolet, Beth A., Felix Boakye-Agyeman, Barrie Harper, Kristen Holland, Andrew Lewandowski, Nicole Stefanko, Chiara Melloni, and Chiara Pediatric Trials Network Steering Committee (See Acknowledgments for a listing of committee members.). “Systemic timolol exposure following topical application to infantile hemangiomas.” J Am Acad Dermatol 82, no. 3 (March 2020): 733–36. https://doi.org/10.1016/j.jaad.2019.02.029.
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  - McMichael, Ali B. V., Christoph P. Hornik, Susan R. Hupp, Sharon E. Gordon, and Caroline P. Ozment. “Correlation Among Antifactor Xa, Activated Partial Thromboplastin Time, and Heparin Dose and Association with Pediatric Extracorporeal Membrane Oxygenation Complications.” Asaio J 66, no. 3 (March 2020): 307–13. https://doi.org/10.1097/MAT.0000000000000986.
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  - Jackson, Wesley, Genevieve Taylor, Nicolas A. Bamat, Kanecia Zimmerman, Reese Clark, Daniel K. Benjamin, Matthew M. Laughon, Rachel G. Greenberg, and Christoph P. Hornik. “Outcomes associated with surfactant in more mature and larger premature infants with respiratory distress syndrome.” J Perinatol, February 20, 2020. https://doi.org/10.1038/s41372-020-0625-1.
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  - Hill, Kevin D., H Scott Baldwin, David P. Bichel, Ryan J. Butts, Reid C. Chamberlain, Alicia M. Ellis, Eric M. Graham, et al. “Rationale and design of the STeroids to REduce Systemic inflammation after infant heart Surgery (STRESS) trial.” Am Heart J 220 (February 2020): 192–202. https://doi.org/10.1016/j.ahj.2019.11.016.
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  - Hornik, Christoph P., Amy A. Gelfand, Christina L. Szperka, Tara Pezzuto, Amanda Utevsky, Shirley Kessel, Susan McCune, John J. Alexander, Daniel K. Benjamin, and Michael Cohen-Wolkowiez. “Development of a Prospective Real-World Data Clinical Registry of Children and Adolescents With Migraine.” Headache 60, no. 2 (February 2020): 405–15. https://doi.org/10.1111/head.13714.
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  - Beechinor, Ryan J., Michael Cohen-Wolkowiez, Theresa Jasion, Christoph P. Hornik, Jason E. Lang, Robert Hernandez, and Daniel Gonzalez. “A Dried Blood Spot Analysis for Solithromycin in Adolescents, Children, and Infants: A Short Communication.” Ther Drug Monit 41, no. 6 (December 2019): 761–65. https://doi.org/10.1097/FTD.0000000000000670.
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  - Gonzalez, Daniel, Matthew M. Laughon, P Brian Smith, Shufan Ge, Namasivayam Ambalavanan, Andrew Atz, Gregory M. Sokol, et al. “Population pharmacokinetics of sildenafil in extremely premature infants.” Br J Clin Pharmacol 85, no. 12 (December 2019): 2824–37. https://doi.org/10.1111/bcp.14111.
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  - Hornik, Christoph P., Daniel Gonzalez, Julie Dumond, Huali Wu, Eric M. Graham, Kevin D. Hill, and Michael Cohen-Wolkowiez. “Population Pharmacokinetic/Pharmacodynamic Modeling of Methylprednisolone in Neonates Undergoing Cardiopulmonary Bypass.” Cpt Pharmacometrics Syst Pharmacol 8, no. 12 (December 2019): 913–22. https://doi.org/10.1002/psp4.12470.
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  - Hornik, Christoph P., Ram Yogev, Peter M. Mourani, Kevin M. Watt, Janice E. Sullivan, Andrew M. Atz, David Speicher, et al. “Population Pharmacokinetics of Milrinone in Infants, Children, and Adolescents.” J Clin Pharmacol 59, no. 12 (December 2019): 1606–19. https://doi.org/10.1002/jcph.1499.
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  - Gonski, Samantha, Susan R. Hupp, C Michael Cotten, Reese H. Clark, Matthew Laughon, Kevin Watt, Christoph P. Hornik, Karan Kumar, P Brian Smith, and Rachel G. Greenberg. “Risk of development of treated retinopathy of prematurity in very low birth weight infants.” J Perinatol 39, no. 11 (November 2019): 1562–68. https://doi.org/10.1038/s41372-019-0487-6.
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  - Thompson, Elizabeth J., Huali Wu, Chiara Melloni, Stephen Balevic, Janice E. Sullivan, Matthew Laughon, Kira M. Clark, et al. “Population Pharmacokinetics of Doxycycline in Children.” Antimicrob Agents Chemother, September 23, 2019. https://doi.org/10.1128/AAC.01508-19.
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  - Puia-Dumitrescu, Mihai, P Brian Smith, Jian Zhao, Angela Soriano, Elizabeth H. Payne, Barrie Harper, Ellen Bendel-Stenzel, et al. “Dosing and Safety of Off-label Use of Caffeine Citrate in Premature Infants.” J Pediatr 211 (August 2019): 27-32.e1. https://doi.org/10.1016/j.jpeds.2019.04.028.
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  - Thompson, Elizabeth J., Huali Wu, Anil Maharaj, Andrea N. Edginton, Stephen J. Balevic, Marjan Cobbaert, Anthony P. Cunningham, Christoph P. Hornik, and Michael Cohen-Wolkowiez. “Physiologically Based Pharmacokinetic Modeling for Trimethoprim and Sulfamethoxazole in Children.” Clin Pharmacokinet 58, no. 7 (July 2019): 887–98. https://doi.org/10.1007/s40262-018-00733-1.
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  - Maharaj, Anil R., Huali Wu, Christoph P. Hornik, and Michael Cohen-Wolkowiez. “Pitfalls of using numerical predictive checks for population physiologically-based pharmacokinetic model evaluation.” J Pharmacokinet Pharmacodyn 46, no. 3 (June 2019): 263–72. https://doi.org/10.1007/s10928-019-09636-5.
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  - Smith, P Brian, C Michael Cotten, Mark L. Hudak, Janice E. Sullivan, Brenda B. Poindexter, Michael Cohen-Wolkowiez, Felix Boakye-Agyeman, et al. “Rifampin Pharmacokinetics and Safety in Preterm and Term Infants.” Antimicrob Agents Chemother 63, no. 6 (June 2019). https://doi.org/10.1128/AAC.00284-19.
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  - Thibault, Dylan, Amelia S. Wallace, Marshall L. Jacobs, Christoph P. Hornik, John M. Costello, Gregory F. Fleming, Jeffrey P. Jacobs, et al. “Postoperative Transcatheter Interventions in Children Undergoing Congenital Heart Surgery.” Circ Cardiovasc Interv 12, no. 6 (June 2019): e007853. https://doi.org/10.1161/CIRCINTERVENTIONS.119.007853.
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  - Kumar, Karan R., and Christoph P. Hornik. “Commentary: Singling out single ventricles after Fontan.” J Thorac Cardiovasc Surg 157, no. 5 (May 2019): 2016–17. https://doi.org/10.1016/j.jtcvs.2018.11.018.
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  - Shakhnovich, Valentina, Christoph P. Hornik, Gregory L. Kearns, Jaylene Weigel, and Susan M. Abdel-Rahman. “How to Conduct Clinical Trials in Children: A Tutorial.” Clin Transl Sci 12, no. 3 (May 2019): 218–30. https://doi.org/10.1111/cts.12615.
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  - Taylor, Genevieve, Wesley Jackson, Christoph P. Hornik, Alec Koss, Sreekar Mantena, Kenya Homsley, Blair Gattis, et al. “Surfactant Administration in Preterm Infants: Drug Development Opportunities.” J Pediatr 208 (May 2019): 163–68. https://doi.org/10.1016/j.jpeds.2018.11.041.
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  - Watt, Kevin M., Christoph P. Hornik, Stephen J. Balevic, Gratias Mundakel, C Michael Cotten, Barrie Harper, Daniel K. Benjamin, et al. “Pharmacokinetics of ticarcillin-clavulanate in premature infants.” Br J Clin Pharmacol 85, no. 5 (May 2019): 1021–27. https://doi.org/10.1111/bcp.13882.
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  - Hornik, Christoph P., Andrew M. Atz, Catherine Bendel, Francis Chan, Kevin Downes, Robert Grundmeier, Ben Fogel, et al. “Creation of a Multicenter Pediatric Inpatient Data Repository Derived from Electronic Health Records.” Appl Clin Inform 10, no. 2 (March 2019): 307–15. https://doi.org/10.1055/s-0039-1688477.
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  - Pelletier, Jonathan H., Karan R. Kumar, Rachel Engen, Adam Bensimhon, Jennifer D. Varner, Michelle N. Rheault, Tarak Srivastava, et al. “Correction to: Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings : A Midwest Pediatric Nephrology Consortium (MWPNC) study.” Pediatr Nephrol 34, no. 3 (March 2019): 539. https://doi.org/10.1007/s00467-018-4103-3.
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  - McCrary, Andrew W., Piers C. A. Barker, Rachel D. Torok, Tracy G. Spears, Jennifer S. Li, Christoph P. Hornik, and Matthew M. Laughon. “Agreement of an echocardiogram-based diagnosis of pulmonary hypertension in infants at risk for bronchopulmonary dysplasia among masked reviewers.” J Perinatol 39, no. 2 (February 2019): 248–55. https://doi.org/10.1038/s41372-018-0277-6.
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  - Thompson, Elizabeth J., Krystle Perez, Christoph P. Hornik, P Brian Smith, Reese H. Clark, Matthew Laughon, and Matthew Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee. “Sildenafil Exposure in the Neonatal Intensive Care Unit.” Am J Perinatol 36, no. 3 (February 2019): 262–67. https://doi.org/10.1055/s-0038-1667378.
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  - Al-Subu, Awni M., Christoph P. Hornik, Ira M. Cheifetz, Andrew J. Lodge, and George Ofori-Amanfo. “Correlation between Regional Cerebral Saturation and Invasive Cardiac Index Monitoring after Heart Transplantation Surgery.” J Pediatr Intensive Care 7, no. 4 (December 2018): 196–200. https://doi.org/10.1055/s-0038-1660788.
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  - Puia-Dumitrescu, Mihai, Olivia M. Bretzius, Nia Brown, James A. Fitz-Henley, Rebecca Ssengonzi, Caroline S. Wechsler, Keyaria D. Gray, et al. “Evaluation of Gentamicin Exposure in the Neonatal Intensive Care Unit and Hearing Function at Discharge.” J Pediatr 203 (December 2018): 131–36. https://doi.org/10.1016/j.jpeds.2018.07.101.
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  - Barker, Piers C. A., Gregory H. Tatum, Michael J. Campbell, Michael G. W. Camitta, Angelo S. Milazzo, Christoph P. Hornik, Amanda French, and Stephen G. Miller. “Improving maternal-infant bonding after prenatal diagnosis of CHD.” Cardiol Young 28, no. 11 (November 2018): 1306–15. https://doi.org/10.1017/S104795111800121X.
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  - Ku, Lawrence C., Christoph P. Hornik, Ryan J. Beechinor, James M. Chamberlain, Jeffrey T. Guptill, Barrie Harper, Edmund V. Capparelli, et al. “Population Pharmacokinetics and Exploratory Exposure-Response Relationships of Diazepam in Children Treated for Status Epilepticus.” Cpt Pharmacometrics Syst Pharmacol 7, no. 11 (November 2018): 718–27. https://doi.org/10.1002/psp4.12349.
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  - Kumar, Karan R., David A. Clark, Evan M. Kim, Jasmine D. Perry, Kaylyn Wright, Sheikisha A. Thomas, Elizabeth J. Thompson, et al. “Association of Atrial Septal Defects and Bronchopulmonary Dysplasia in Premature Infants.” J Pediatr 202 (November 2018): 56-62.e2. https://doi.org/10.1016/j.jpeds.2018.07.024.
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  - Pelletier, Jonathan H., Karan R. Kumar, Rachel Engen, Adam Bensimhon, Jennifer D. Varner, Michelle N. Rheault, Tarak Srivastava, et al. “Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings.” Pediatr Nephrol 33, no. 10 (October 2018): 1773–80. https://doi.org/10.1007/s00467-018-3994-3.
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  - Koeberl, Dwight D., Laura E. Case, Edward C. Smith, Crista Walters, Sang-Oh Han, Yanzhen Li, Wei Chen, et al. “Correction of Biochemical Abnormalities and Improved Muscle Function in a Phase I/II Clinical Trial of Clenbuterol in Pompe Disease.” Mol Ther 26, no. 9 (September 5, 2018): 2304–14. https://doi.org/10.1016/j.ymthe.2018.06.023.
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  - Ge, Shufan, Ryan J. Beechinor, Christoph P. Hornik, Joseph F. Standing, Kanecia Zimmerman, Michael Cohen-Wolkowiez, Matthew M. Laughon, Reese Clark, and Daniel Gonzalez. “External Evaluation of a Gentamicin Infant Population Pharmacokinetic Model Using Data from a National Electronic Health Record Database.” Antimicrob Agents Chemother 62, no. 9 (September 2018). https://doi.org/10.1128/AAC.00669-18.
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  - Sherwin, Jennifer, Elizabeth Thompson, Kevin D. Hill, Kevin Watt, Andrew J. Lodge, Daniel Gonzalez, and Christoph P. Hornik. “Clinical pharmacology considerations for children supported with ventricular assist devices.” Cardiol Young 28, no. 9 (September 2018): 1082–90. https://doi.org/10.1017/S1047951118001075.
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  - Gonzalez, Daniel, Laura P. James, Amira Al-Uzri, Miroslava Bosheva, Felice C. Adler-Shohet, Susan R. Mendley, John S. Bradley, et al. “Population Pharmacokinetics and Safety of Solithromycin following Intravenous and Oral Administration in Infants, Children, and Adolescents.” Antimicrob Agents Chemother 62, no. 8 (August 2018). https://doi.org/10.1128/AAC.00692-18.
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  - Gonzalez, Daniel, Laura P. James, Amira Al-Uzri, Miroslava Bosheva, Felice C. Adler-Shohet, Susan R. Mendley, John S. Bradley, et al. “Population Pharmacokinetics and Safety of Solithromycin following Intravenous and Oral Administration in Infants, Children, and Adolescents.” Antimicrobial Agents and Chemotherapy 62, no. 8 (August 1, 2018). https://doi.org/10.1128/AAC.00692-18;e00692-18.
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  - Thompson, Elizabeth J., Rachel G. Greenberg, Karan Kumar, Matthew Laughon, P Brian Smith, Reese H. Clark, Andromeda Crowell, et al. “Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight.” J Pediatr 199 (August 2018): 231–36. https://doi.org/10.1016/j.jpeds.2018.03.067.
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  - Wong, Judith Jm, Christoph P. Hornik, Yee Hui Mok, Tsee Foong Loh, and Jan Hau Lee. “Performance of the Paediatric Index of Mortality 3 and Paediatric Logistic Organ Dysfunction 2 Scores in Critically Ill Children.” Ann Acad Med Singapore 47, no. 8 (August 2018): 285–90.
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  - Al-Subu, Awni, Edmund Jooste, Christoph P. Hornik, Gregory A. Fleming, Ira M. Cheifetz, and George Ofori-Amanfo. “Correlation between minute carbon dioxide elimination and pulmonary blood flow in single-ventricle patients after stage 1 palliation and 2-ventricle patients with intracardiac shunts: A pilot study.” Paediatr Anaesth 28, no. 7 (July 2018): 618–24. https://doi.org/10.1111/pan.13423.
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  - Dallefeld, Samantha H., Andrew M. Atz, Ram Yogev, Janice E. Sullivan, Amira Al-Uzri, Susan R. Mendley, Matthew Laughon, et al. “A pharmacokinetic model for amiodarone in infants developed from an opportunistic sampling trial and published literature data.” J Pharmacokinet Pharmacodyn 45, no. 3 (June 2018): 419–30. https://doi.org/10.1007/s10928-018-9576-y.
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  - Maharaj, Anil R., Daniel Gonzalez, Michael Cohen-Wolkowiez, Christoph P. Hornik, and Andrea N. Edginton. “Improving Pediatric Protein Binding Estimates: An Evaluation of α1-Acid Glycoprotein Maturation in Healthy and Infected Subjects.” Clin Pharmacokinet 57, no. 5 (May 2018): 577–89. https://doi.org/10.1007/s40262-017-0576-7.
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  - Hornik, Christoph P., Daniel Gonzalez, John van den Anker, Andrew M. Atz, Ram Yogev, Brenda B. Poindexter, Kee Chong Ng, et al. “Population Pharmacokinetics of Intramuscular and Intravenous Ketamine in Children.” J Clin Pharmacol, April 20, 2018. https://doi.org/10.1002/jcph.1116.
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  - Heath, Travis S., Rachel G. Greenberg, Susan R. Hupp, David A. Turner, Christoph P. Hornik, and Kanecia O. Zimmerman. “Effects of Methadone on Corrected Q-T Interval Prolongation in Critically Ill Children.” J Pediatr Pharmacol Ther 23, no. 2 (March 2018): 119–24. https://doi.org/10.5863/1551-6776-23.2.119.
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  - Lee, J. H., B. H. Quek, C. P. Hornik, R. Shahdadpuri, and D. A. Turner. “Trainees’ perception of education in communication and professionalism across two programs in two countries.” Proceedings of Singapore Healthcare 27, no. 1 (March 1, 2018): 6–11. https://doi.org/10.1177/2010105817715270.
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  - Testoni, Daniela, Christoph P. Hornik, Ruth Guinsburg, Reese H. Clark, Rachel G. Greenberg, Daniel K. Benjamin, and P Brian Smith. “Early lumbar puncture and risk of intraventricular hemorrhage in very low birth weight infants.” Early Hum Dev 117 (February 2018): 1–6. https://doi.org/10.1016/j.earlhumdev.2017.11.013.
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  - Autmizguine, Julie, Chiara Melloni, Christoph P. Hornik, Samantha Dallefeld, Barrie Harper, Ram Yogev, Janice E. Sullivan, et al. “Population Pharmacokinetics of Trimethoprim-Sulfamethoxazole in Infants and Children.” Antimicrob Agents Chemother 62, no. 1 (January 2018). https://doi.org/10.1128/AAC.01813-17.
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  - Hornik, Christoph P., Nikolas J. Onufrak, P Brian Smith, Michael Cohen-Wolkowiez, Matthew M. Laughon, Reese H. Clark, and Daniel Gonzalez. “Association between oral sildenafil dosing, predicted exposure, and systemic hypotension in hospitalised infants.” Cardiol Young 28, no. 1 (January 2018): 85–92. https://doi.org/10.1017/S1047951117001639.
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  - Watt, Kevin M., Debbie Avant, Jennifer Sherwin, Daniel K. Benjamin, Christoph Hornik, Jennifer S. Li, and P Brian Smith. “Effect of renal function on antihypertensive drug safety and efficacy in children.” Pediatr Nephrol 33, no. 1 (January 2018): 139–46. https://doi.org/10.1007/s00467-017-3763-8.
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  - Walter, Emmanuel B., Christoph P. Hornik, Lisa Grohskopf, Charles E. McGee, Christopher A. Todd, Oidda I. Museru, Lynn Harrington, and Karen R. Broder. “The effect of antipyretics on immune response and fever following receipt of inactivated influenza vaccine in young children.” Vaccine 35, no. 48 Pt B (December 4, 2017): 6664–71. https://doi.org/10.1016/j.vaccine.2017.10.020.
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  - Hwang, Michael F., Ryan J. Beechinor, Kelly C. Wade, Daniel K. Benjamin, P Brian Smith, Christoph P. Hornik, Edmund V. Capparelli, et al. “External Evaluation of Two Fluconazole Infant Population Pharmacokinetic Models.” Antimicrob Agents Chemother 61, no. 12 (December 2017). https://doi.org/10.1128/AAC.01352-17.
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  - Salerno, Sara N., Andrea Edginton, Michael Cohen-Wolkowiez, Christoph P. Hornik, Kevin M. Watt, Brian D. Jamieson, and Daniel Gonzalez. “Development of an Adult Physiologically Based Pharmacokinetic Model of Solithromycin in Plasma and Epithelial Lining Fluid.” Cpt Pharmacometrics Syst Pharmacol 6, no. 12 (December 2017): 814–22. https://doi.org/10.1002/psp4.12252.
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  - Hornik, Christoph P., Huali Wu, Andrea N. Edginton, Kevin Watt, Michael Cohen-Wolkowiez, and Daniel Gonzalez. “Development of a Pediatric Physiologically-Based Pharmacokinetic Model of Clindamycin Using Opportunistic Pharmacokinetic Data.” Clin Pharmacokinet 56, no. 11 (November 2017): 1343–53. https://doi.org/10.1007/s40262-017-0525-5.
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  - Kemper, Alex R., Elizabeth D. Barnett, Emmanuel B. Walter, Christoph Hornik, Natalie Pierre-Joseph, Karen R. Broder, Michael Silverstein, and Theresa Harrington. “Drinking Water to Prevent Postvaccination Presyncope in Adolescents: A Randomized Trial.” Pediatrics 140, no. 5 (November 2017). https://doi.org/10.1542/peds.2017-0508.
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  - Lee, Jan Hau, Rachel G. Greenberg, Bin H. Quek, Reese H. Clark, Matthew M. Laughon, P Brian Smith, and Christoph P. Hornik. “Association between early echocardiography, therapy for patent ductus arteriosus, and outcomes in very low birth weight infants.” Cardiol Young 27, no. 9 (November 2017): 1732–39. https://doi.org/10.1017/S1047951117001081.
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  - Pelletier, Jonathan H., Sarah Blanchard, Reid C. Chamberlain, Christoph P. Hornik, Michael J. Campbell, and Kevin D. Hill. “The Use of Echocardiography for Pediatric Patients Presenting with Syncope.” J Pediatr 190 (November 2017): 43–48. https://doi.org/10.1016/j.jpeds.2017.07.010.
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  - Schueller, Maya, Rachel G. Greenberg, P Brian Smith, Matthew M. Laughon, Reese H. Clark, and Christoph P. Hornik. “In-Hospital Outcomes Following Extracorporeal Membrane Oxygenation in a Retrospective Cohort of Infants.” Am J Perinatol 34, no. 13 (November 2017): 1347–53. https://doi.org/10.1055/s-0037-1603593.
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  - Jacobs, Marshall L., Jeffrey P. Jacobs, Kevin D. Hill, Christoph Hornik, Sean M. O’Brien, Sara K. Pasquali, David Vener, et al. “The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2017 Update on Research.” Ann Thorac Surg 104, no. 3 (September 2017): 731–41. https://doi.org/10.1016/j.athoracsur.2017.07.001.
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  - Salerno, Sara, Christoph P. Hornik, Michael Cohen-Wolkowiez, P Brian Smith, Lawrence C. Ku, Matthew S. Kelly, Reese Clark, Daniel Gonzalez, and Daniel Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee. “Use of Population Pharmacokinetics and Electronic Health Records to Assess Piperacillin-Tazobactam Safety in Infants.” Pediatr Infect Dis J 36, no. 9 (September 2017): 855–59. https://doi.org/10.1097/INF.0000000000001610.
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  - O’Byrne, Michael L., Sunghee Kim, Christoph P. Hornik, Babatunde A. Yerokun, Roland A. Matsouaka, Jeffrey P. Jacobs, Marshall L. Jacobs, and Richard A. Jonas. “Effect of Obesity and Underweight Status on Perioperative Outcomes of Congenital Heart Operations in Children, Adolescents, and Young Adults: An Analysis of Data From the Society of Thoracic Surgeons Database.” Circulation 136, no. 8 (August 22, 2017): 704–18. https://doi.org/10.1161/CIRCULATIONAHA.116.026778.
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  - Chamberlain, Reid C., Jonathan H. Pelletier, Sarah Blanchard, Christoph P. Hornik, Kevin D. Hill, and Michael J. Campbell. “Evaluating Appropriate Use of Pediatric Echocardiograms for Chest Pain in Outpatient Clinics.” J Am Soc Echocardiogr 30, no. 7 (July 2017): 708–13. https://doi.org/10.1016/j.echo.2017.03.008.
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  - Jackson, W., C. P. Hornik, J. A. Messina, K. Guglielmo, A. Watwe, G. Delancy, A. Valdez, et al. “In-hospital outcomes of premature infants with severe bronchopulmonary dysplasia.” J Perinatol 37, no. 7 (July 2017): 853–56. https://doi.org/10.1038/jp.2017.49.
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  - Ravisankar, Srikanth, Devon Kuehn, Reese H. Clark, Rachel G. Greenberg, P Brian Smith, and Christoph P. Hornik. “Antihypertensive drug exposure in premature infants from 1997 to 2013.” Cardiol Young 27, no. 5 (July 2017): 905–11. https://doi.org/10.1017/S1047951116001591.
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  - Andersen, Nicholas D., James M. Meza, Matthew R. Byler, Andrew J. Lodge, Kevin D. Hill, Christoph P. Hornik, and Robert D. B. Jaquiss. “Comparison of right ventricle-pulmonary artery shunt position in the Single Ventricle Reconstruction trial.” J Thorac Cardiovasc Surg 153, no. 6 (June 2017): 1490-1500.e1. https://doi.org/10.1016/j.jtcvs.2016.10.104.
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  - Downey, L. C., C. M. Cotten, C. P. Hornik, M. M. Laughon, V. N. Tolia, R. H. Clark, and P. B. Smith. “Association of in utero magnesium exposure and spontaneous intestinal perforations in extremely low birth weight infants.” J Perinatol 37, no. 6 (June 2017): 641–44. https://doi.org/10.1038/jp.2016.274.
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  - Ericson, Jessica E., Martyn Gostelow, Julie Autmizguine, Christoph P. Hornik, Reese H. Clark, Daniel K. Benjamin, P Brian Smith, and P Brian Pediatric Trials Network Executive Committee and Investigators. “Safety of High-dose Acyclovir in Infants With Suspected and Confirmed Neonatal Herpes Simplex Virus Infections.” Pediatr Infect Dis J 36, no. 4 (April 2017): 369–73. https://doi.org/10.1097/INF.0000000000001451.
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  - Lee, Jin A., Brooke Sauer, William Tuminski, Jiyu Cheong, John Fitz-Henley, Megan Mayers, Chidera Ezuma-Igwe, et al. “Effectiveness of Granulocyte Colony-Stimulating Factor in Hospitalized Infants with Neutropenia.” Am J Perinatol 34, no. 5 (April 2017): 458–64. https://doi.org/10.1055/s-0036-1593349.
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  - Virkud, Yamini V., Christoph P. Hornik, Daniel K. Benjamin, Matthew M. Laughon, Reese H. Clark, Rachel G. Greenberg, and P Brian Smith. “Respiratory Support for Very Low Birth Weight Infants Receiving Dexamethasone.” J Pediatr 183 (April 2017): 26-30.e3. https://doi.org/10.1016/j.jpeds.2016.12.035.
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  - Chu, Patricia Y., Jennifer S. Li, Andrzej S. Kosinski, Christoph P. Hornik, and Kevin D. Hill. “Congenital Heart Disease in Premature Infants 25-32 Weeks' Gestational Age.” J Pediatr 181 (February 2017): 37-41.e1. https://doi.org/10.1016/j.jpeds.2016.10.033.
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  - Chu, Patricia Y., Christoph P. Hornik, Jennifer S. Li, Michael J. Campbell, and Kevin D. Hill. “Respiratory syncytial virus hospitalisation trends in children with haemodynamically significant heart disease, 1997-2012.” Cardiol Young 27, no. 1 (January 2017): 16–25. https://doi.org/10.1017/S1047951116000470.
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  - Ku, Lawrence C., Kanecia Zimmerman, Daniel K. Benjamin, Reese H. Clark, Christoph P. Hornik, P Brian Smith, and P Brian Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. “Safety of Enalapril in Infants Admitted to the Neonatal Intensive Care Unit.” Pediatr Cardiol 38, no. 1 (January 2017): 155–61. https://doi.org/10.1007/s00246-016-1496-2.
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  - Lloyd, Jessica C., Christoph P. Hornik, Daniel K. Benjamin, Reese H. Clark, Jonathan C. Routh, and P Brian Smith. “Incidence of Breakthrough Urinary Tract Infection in Hospitalized Infants Receiving Antibiotic Prophylaxis.” Clin Pediatr (Phila) 56, no. 1 (January 2017): 65–70. https://doi.org/10.1177/0009922816638664.
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  - Thakkar, Nilay, Sara Salerno, Christoph P. Hornik, and Daniel Gonzalez. “Clinical Pharmacology Studies in Critically Ill Children.” Pharm Res 34, no. 1 (January 2017): 7–24. https://doi.org/10.1007/s11095-016-2033-y.
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  - Zimmerman, Kanecia O., P Brian Smith, Daniel K. Benjamin, Matthew Laughon, Reese Clark, Chani Traube, Til Stürmer, and Christoph P. Hornik. “Sedation, Analgesia, and Paralysis during Mechanical Ventilation of Premature Infants.” J Pediatr 180 (January 2017): 99-104.e1. https://doi.org/10.1016/j.jpeds.2016.07.001.
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  - Ku, Lawrence C., Huali Wu, Rachel G. Greenberg, Kevin D. Hill, Daniel Gonzalez, Christoph P. Hornik, Alysha Berezny, et al. “Use of Therapeutic Drug Monitoring, Electronic Health Record Data, and Pharmacokinetic Modeling to Determine the Therapeutic Index of Phenytoin and Lamotrigine.” Ther Drug Monit 38, no. 6 (December 2016): 728–37. https://doi.org/10.1097/FTD.0000000000000354.
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  - Autmizguine, Julie, Christoph P. Hornik, Daniel K. Benjamin, Kim L. R. Brouwer, Susan R. Hupp, Michael Cohen-Wolkowiez, and Kevin M. Watt. “Pharmacokinetics and Safety of Micafungin in Infants Supported With Extracorporeal Membrane Oxygenation.” Pediatr Infect Dis J 35, no. 11 (November 2016): 1204–10. https://doi.org/10.1097/INF.0000000000001268.
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  - Hornik, Christoph P., Daniel K. Benjamin, P Brian Smith, Michael J. Pencina, Adriana H. Tremoulet, Edmund V. Capparelli, Jessica E. Ericson, Reese H. Clark, Michael Cohen-Wolkowiez, and Michael Best Pharmaceuticals for Children Act—Pediatric Trials Network. “Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates.” J Pediatr 178 (November 2016): 125-129.e1. https://doi.org/10.1016/j.jpeds.2016.07.011.
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  - Lee, J. H., R. G. Greenberg, B. H. Quek, R. H. Clark, M. M. Laughon, P. B. Smith, and C. P. Hornik. “ASSOCIATION BETWEEN EARLY ECHOCARDIOGRAPHY, PATENT DUCTUS ARTERIOSUS THERAPY, AND OUTCOMES IN VERY LOW BIRTH WEIGHT INFANTS.” European Journal of Pediatrics 175, no. 11 (November 1, 2016): 1581–82.
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  - Morgan, Stephen, Christoph P. Hornik, Niyati Patel, Walter L. Williford, David A. Turner, and Ira M. Cheifetz. “Continuous High-Frequency Oscillation Therapy in Invasively Ventilated Pediatric Subjects in the Critical Care Setting.” Respir Care 61, no. 11 (November 2016): 1451–55. https://doi.org/10.4187/respcare.04368.
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  - Nelson-McMillan, Kristen, Christoph P. Hornik, Xia He, Luca A. Vricella, Jeffrey P. Jacobs, Kevin D. Hill, Sara K. Pasquali, Diane E. Alejo, Duke E. Cameron, and Marshall L. Jacobs. “Delayed Sternal Closure in Infant Heart Surgery-The Importance of Where and When: An Analysis of the STS Congenital Heart Surgery Database.” Ann Thorac Surg 102, no. 5 (November 2016): 1565–72. https://doi.org/10.1016/j.athoracsur.2016.08.081.
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  - Hornik, Christoph P., Eric M. Graham, Kevin Hill, Jennifer S. Li, George Ofori-Amanfo, Reese H. Clark, and P Brian Smith. “Cardiopulmonary resuscitation in hospitalized infants.” Early Hum Dev 101 (October 2016): 17–22. https://doi.org/10.1016/j.earlhumdev.2016.03.015.
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  - Zimmerman, Kanecia O., Huali Wu, Rachel Greenberg, Jeffrey T. Guptill, Kevin Hill, Uptal D. Patel, Lawrence Ku, et al. “Therapeutic Drug Monitoring, Electronic Health Records, and Pharmacokinetic Modeling to Evaluate Sirolimus Drug Exposure-Response Relationships in Renal Transplant Patients.” Ther Drug Monit 38, no. 5 (October 2016): 600–606. https://doi.org/10.1097/FTD.0000000000000313.
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  - Greenberg, Rachel G., Chiara Melloni, Huali Wu, Daniel Gonzalez, Lawrence Ku, Kevin D. Hill, Christoph P. Hornik, Michael Cohen-Wolkowiez, and Jeffrey T. Guptill. “Therapeutic Index Estimation of Antiepileptic Drugs: A Systematic Literature Review Approach.” Clin Neuropharmacol 39, no. 5 (September 2016): 232–40. https://doi.org/10.1097/WNF.0000000000000172.
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  - Jacobs, Marshall L., Jeffrey P. Jacobs, Sara K. Pasquali, Kevin D. Hill, Christoph Hornik, Sean M. O’Brien, David M. Shahian, Robert H. Habib, and Fred H. Edwards. “The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2016 Update on Research.” Ann Thorac Surg 102, no. 3 (September 2016): 688–95. https://doi.org/10.1016/j.athoracsur.2016.07.015.
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  - Zimmerman, Kanecia, Martin Putera, Christoph P. Hornik, P. Brian Smith, Daniel K. Benjamin, Yeruk Mulugeta, Gilbert J. Burckart, Michael Cohen-Wolkowiez, and Daniel Gonzalez. “Exposure Matching of Pediatric Anti-infective Drugs: Review of Drugs Submitted to the Food and Drug Administration for Pediatric Approval.” Clin Ther 38, no. 9 (September 2016): 1995–2005. https://doi.org/10.1016/j.clinthera.2016.06.003.
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  - Hornik, Christoph, and Jon Meliones. “Pulmonary Edema and Hypoxic Respiratory Failure.” Pediatr Crit Care Med 17, no. 8 Suppl 1 (August 2016): S178–81. https://doi.org/10.1097/PCC.0000000000000823.
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  - Plummer, Sarah T., Christoph P. Hornik, Hamilton Baker, Gregory A. Fleming, Susan Foerster, M Eric Ferguson, Andrew C. Glatz, et al. “Maladaptive aortic properties after the Norwood procedure: An angiographic analysis of the Pediatric Heart Network Single Ventricle Reconstruction Trial.” J Thorac Cardiovasc Surg 152, no. 2 (August 2016): 471-479.e3. https://doi.org/10.1016/j.jtcvs.2016.03.091.
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  - Romaine, Andrew, Daniel Ye, Zachary Ao, Francia Fang, Octavious Johnson, Taylor Blake, Daniel K. Benjamin, et al. “Safety of histamine-2 receptor blockers in hospitalized VLBW infants.” Early Hum Dev 99 (August 2016): 27–30. https://doi.org/10.1016/j.earlhumdev.2016.05.010.
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  - Fleming, Geoffrey M., Richard B. Mink, Christoph Hornik, Amanda R. Emke, Michael L. Green, Katherine Mason, Toni Petrillo, et al. “Developing a Tool to Assess Placement of Central Venous Catheters in Pediatrics Patients.” J Grad Med Educ 8, no. 3 (July 2016): 346–52. https://doi.org/10.4300/JGME-D-15-00365.1.
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  - Hartz, Jacob, Jennifer S. Li, Ololade O. Akintoye, and Christoph P. Hornik. “Clinicians' Adherence to Guidelines on Evaluation of Hypertension in Children and Adolescents.” World J Pediatr Congenit Heart Surg 7, no. 4 (July 2016): 440–45. https://doi.org/10.1177/2150135116641877.
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  - Lee, Jan Hau, P Brian Smith, M Bin Huey Quek, Matthew M. Laughon, Reese H. Clark, and Christoph P. Hornik. “Risk Factors and In-Hospital Outcomes following Tracheostomy in Infants.” J Pediatr 173 (June 2016): 39-44.e1. https://doi.org/10.1016/j.jpeds.2016.01.072.
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  - Mastropietro, Christopher W., Brian D. Benneyworth, Mark Turrentine, Amelia S. Wallace, Christoph P. Hornik, Jeffrey P. Jacobs, and Marshall L. Jacobs. “Tracheostomy After Operations for Congenital Heart Disease: An Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database.” Ann Thorac Surg 101, no. 6 (June 2016): 2285–92. https://doi.org/10.1016/j.athoracsur.2016.01.046.
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  - Hornik, Christoph P., Ashley L. Sherwood, C Michael Cotten, Matthew M. Laughon, Reese H. Clark, and P Brian Smith. “Daily mortality of infants born at less than 30weeks' gestation.” Early Hum Dev 96 (May 2016): 27–30. https://doi.org/10.1016/j.earlhumdev.2016.03.003.
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  - Gonzalez, Daniel, Debra L. Palazzi, Leena Bhattacharya-Mithal, Amira Al-Uzri, Laura P. James, John Bradley, Natalie Neu, et al. “Solithromycin Pharmacokinetics in Plasma and Dried Blood Spots and Safety in Adolescents.” Antimicrob Agents Chemother 60, no. 4 (April 2016): 2572–76. https://doi.org/10.1128/AAC.02561-15.
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  - Gulack, Brian C., Matthew M. Laughon, Reese H. Clark, Terrance Burgess, Sybil Robinson, Abdurrauf Muhammad, Angela Zhang, et al. “Enteral Feeding with Human Milk Decreases Time to Discharge in Infants following Gastroschisis Repair.” J Pediatr 170 (March 2016): 85–89. https://doi.org/10.1016/j.jpeds.2015.11.046.
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  - Lee, Jan Hau, Christoph P. Hornik, Daniela Testoni, Matthew M. Laughon, C Michael Cotten, Ramiro S. Maldonado, Marc R. Belcastro, Reese H. Clark, and P Brian Smith. “Insulin, Hyperglycemia, and Severe Retinopathy of Prematurity in Extremely Low-Birth-Weight Infants.” Am J Perinatol 33, no. 4 (March 2016): 393–400. https://doi.org/10.1055/s-0035-1565999.
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  - Samiee-Zafarghandy, S., J. N. van den Anker, M. M. Laughon, R. H. Clark, P. B. Smith, C. P. Hornik, and C. P. Pharmaceuticals for Children Act – Pediatric Trials Network Administrative Core Committee. “Sildenafil and retinopathy of prematurity risk in very low birth weight infants.” J Perinatol 36, no. 2 (February 2016): 137–40. https://doi.org/10.1038/jp.2015.126.
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  - McCrary, A. W., J. R. Malowitz, C. P. Hornick, K. D. Hill, C. M. Cotten, G. H. Tatum, and P. C. Barker. “Differences in Eccentricity Index and Systolic-Diastolic Ratio in Extremely Low-Birth-Weight Infants with Bronchopulmonary Dysplasia at Risk of Pulmonary Hypertension.” Am J Perinatol 33, no. 1 (January 2016): 57–62. https://doi.org/10.1055/s-0035-1556757.
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  - Gulack, Brian C., Matthew M. Laughon, Reese H. Clark, Meera N. Sankar, Christoph P. Hornik, and P Brian Smith. “Comparative effectiveness and safety of indomethacin versus ibuprofen for the treatment of patent ductus arteriosus.” Early Hum Dev 91, no. 12 (December 2015): 725–29. https://doi.org/10.1016/j.earlhumdev.2015.08.003.
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  - Chu, Patricia Y., Jennifer S. Li, Andrzej S. Kosinski, Christoph P. Hornik, and Kevin D. Hill. “Epidemiology and Mortality of Very and Extremely Preterm Infants With Congenital Heart Defects.” Circulation 132 (November 10, 2015).
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  - Hornik, Christoph P., R Thomas Collins, Robert D. B. Jaquiss, Jeffrey P. Jacobs, Marshall L. Jacobs, Sara K. Pasquali, Amelia S. Wallace, and Kevin D. Hill. “Combining clinical databases with genetic studies to help advance the causation model of congenital heart disease.” J Thorac Cardiovasc Surg 150, no. 5 (November 2015): 1380–81. https://doi.org/10.1016/j.jtcvs.2015.08.006.
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  - Thaden, Joshua T., Jessica E. Ericson, Heather Cross, Stephen P. Bergin, Julia A. Messina, Vance G. Fowler, Daniel K. Benjamin, et al. “Survival Benefit of Empirical Therapy for Staphylococcus aureus Bloodstream Infections in Infants.” Pediatr Infect Dis J 34, no. 11 (November 2015): 1175–79. https://doi.org/10.1097/INF.0000000000000850.
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  - Pineda, Leslie C., Christoph P. Hornik, Patrick C. Seed, C Michael Cotten, Matthew M. Laughon, Margarita Bidegain, Reese H. Clark, and P. Brian Smith. “Association between positive urine cultures and necrotizing enterocolitis in a large cohort of hospitalized infants.” Early Hum Dev 91, no. 10 (October 2015): 583–86. https://doi.org/10.1016/j.earlhumdev.2015.07.003.
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  - Wisotzkey, Bethany L., Christoph P. Hornik, Amanda S. Green, and Piers C. A. Barker. “Comparison of invasive and non-invasive pressure gradients in aortic arch obstruction.” Cardiol Young 25, no. 7 (October 2015): 1348–57. https://doi.org/10.1017/S1047951114002522.
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  - Arnold, Christopher J., Jessica Ericson, Nathan Cho, James Tian, Shelby Wilson, Vivian H. Chu, Christoph P. Hornik, et al. “Cefepime and Ceftazidime Safety in Hospitalized Infants.” Pediatr Infect Dis J 34, no. 9 (September 2015): 964–68. https://doi.org/10.1097/INF.0000000000000778.
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  - Bergin, Stephen P., Joshua T. Thaden, Jessica E. Ericson, Heather Cross, Julia Messina, Reese H. Clark, Vance G. Fowler, et al. “Neonatal Escherichia coli Bloodstream Infections: Clinical Outcomes and Impact of Initial Antibiotic Therapy.” Pediatr Infect Dis J 34, no. 9 (September 2015): 933–36. https://doi.org/10.1097/INF.0000000000000769.
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  - Ericson, Jessica E., Christopher Arnold, Jomani Cheeseman, Jordan Cho, Sarah Kaneko, Ele’na Wilson, Reese H. Clark, et al. “Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants.” J Pediatr Gastroenterol Nutr 61, no. 3 (September 2015): 334–39. https://doi.org/10.1097/MPG.0000000000000792.
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  - Raman, Sudha R., Stephen D. Demeo, Christoph P. Hornik, Reese Clark, and P Brian Smith. “Immunization Status at Discharge from the Neonatal Intensive Care Unit (NICU).” Pharmacoepidemiology and Drug Safety 24 (September 1, 2015): 13–13.
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  - DeMeo, Stephen D., Sudha R. Raman, Christoph P. Hornik, Catherine C. Wilson, Reese Clark, and P Brian Smith. “Adverse Events After Routine Immunization of Extremely Low-Birth-Weight Infants.” Jama Pediatr 169, no. 8 (August 2015): 740–45. https://doi.org/10.1001/jamapediatrics.2015.0418.
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  - Zimmerman, Kanecia O., Christoph P. Hornik, Lawrence Ku, Kevin Watt, Matthew M. Laughon, Margarita Bidegain, Reese H. Clark, and P Brian Smith. “Sedatives and Analgesics Given to Infants in Neonatal Intensive Care Units at the End of Life.” J Pediatr 167, no. 2 (August 2015): 299-304.e3. https://doi.org/10.1016/j.jpeds.2015.04.059.
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  - Malowitz, Jonathan R., Christoph P. Hornik, Matthew M. Laughon, Daniela Testoni, C Michael Cotten, Reese H. Clark, and P Brian Smith. “Management Practice and Mortality for Infants with Congenital Diaphragmatic Hernia.” Am J Perinatol 32, no. 9 (July 2015): 887–94. https://doi.org/10.1055/s-0035-1544949.
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  - Testoni, Daniela, Christoph P. Hornik, Megan L. Neely, Qinghong Yang, Ann W. McMahon, Reese H. Clark, P Brian Smith, and P Brian Best Pharmaceuticals for Children Act — Pediatric Trials Network Administrative Core Committee. “Safety of octreotide in hospitalized infants.” Early Hum Dev 91, no. 7 (July 2015): 387–92. https://doi.org/10.1016/j.earlhumdev.2015.04.008.
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  - Turner, David A., Geoffrey M. Fleming, Margaret Winkler, K Jane Lee, Melinda F. Hamilton, Christoph P. Hornik, Toni Petrillo-Albarano, Katherine Mason, Richard Mink, and Richard Education in Pediatric Intensive Care Investigators. “Professionalism and Communication Education in Pediatric Critical Care Medicine: The Learner Perspective.” Acad Pediatr 15, no. 4 (July 2015): 380–85. https://doi.org/10.1016/j.acap.2015.02.011.
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  - Becker, Kristian C., Christoph P. Hornik, C Michael Cotten, Reese H. Clark, Kevin D. Hill, P Brian Smith, and Robert W. Lenfestey. “Necrotizing enterocolitis in infants with ductal-dependent congenital heart disease.” Am J Perinatol 32, no. 7 (June 2015): 633–38. https://doi.org/10.1055/s-0034-1390349.
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  - Chu, Patricia Y., Kevin D. Hill, Reese H. Clark, P Brian Smith, and Christoph P. Hornik. “Treatment of supraventricular tachycardia in infants: Analysis of a large multicenter database.” Early Hum Dev 91, no. 6 (June 2015): 345–50. https://doi.org/10.1016/j.earlhumdev.2015.04.001.
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  - Hornik, Christoph P., Ronnie Thomas Collins, Robert D. B. Jaquiss, Jeffrey P. Jacobs, Marshall L. Jacobs, Sara K. Pasquali, Amelia S. Wallace, and Kevin D. Hill. “Adverse cardiac events in children with Williams syndrome undergoing cardiovascular surgery: An analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database.” J Thorac Cardiovasc Surg 149, no. 6 (June 2015): 1516-22.e1. https://doi.org/10.1016/j.jtcvs.2015.02.016.
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  - Arnold, Christopher J., Jessica Ericson, Jordan Kohman, Kaitlyn L. Corey, Morgan Oh, Janet Onabanjo, Christoph P. Hornik, et al. “Rifampin use and safety in hospitalized infants.” Am J Perinatol 32, no. 6 (May 2015): 565–70. https://doi.org/10.1055/s-0034-1543955.
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  - Forsha, Daniel, Niels Risum, Sudarshan Rajagopal, Stephen Dolgner, Christoph Hornik, Huiman Barnhart, Joseph Kisslo, and Piers Barker. “The influence of angle of insonation and target depth on speckle-tracking strain.” J Am Soc Echocardiogr 28, no. 5 (May 2015): 580–86. https://doi.org/10.1016/j.echo.2014.12.015.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Response to letters regarding article, "Cumulative radiation exposure and cancer risk estimation in children with heart disease".” Circulation 131, no. 16 (April 21, 2015): e419–20. https://doi.org/10.1161/CIRCULATIONAHA.114.013266.
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  - Ericson, Jessica E., Joshua Thaden, Heather R. Cross, Reese H. Clark, Vance G. Fowler, Daniel K. Benjamin, Michael Cohen-Wolkowiez, Christoph P. Hornik, P Brian Smith, and P Brian Antibacterial Resistance Leadership Group. “No survival benefit with empirical vancomycin therapy for coagulase-negative staphylococcal bloodstream infections in infants.” Pediatr Infect Dis J 34, no. 4 (April 2015): 371–75. https://doi.org/10.1097/INF.0000000000000573.
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  - Williams, Duane C., Jennifer L. Turi, Christoph P. Hornik, Desiree K. Bonadonna, Walter L. Williford, Richard J. Walczak, Kevin M. Watt, and Ira M. Cheifetz. “Circuit oxygenator contributes to extracorporeal membrane oxygenation-induced hemolysis.” Asaio J 61, no. 2 (March 2015): 190–95. https://doi.org/10.1097/MAT.0000000000000173.
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  - Malowitz, JR, Hornik, CP, Laughon, MM, Testoni, D, Cotten, CM, Clark, RH, and Smith, PB. "Management Practice and Mortality for Infants with Congenital Diaphragmatic Hernia." American Journal of Perinatology 32, no. 9 (February 25, 2015): 887-894. Full Text
  - Kemper, Alex R., Kelly C. Wade, Christoph P. Hornik, Gui-Shuang Ying, Agnieshka Baumritter, Graham E. Quinn, and Graham E. Telemedicine Approaches to Evaluating Acute-phase Retinopathy of Prematurity (e-ROP) Study Cooperative Group. “Retinopathy of prematurity risk prediction for infants with birth weight less than 1251 grams.” J Pediatr 166, no. 2 (February 2015): 257-61.e2. https://doi.org/10.1016/j.jpeds.2014.09.069.
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  - Autmizguine, Julie, Christoph P. Hornik, Daniel K. Benjamin, Matthew M. Laughon, Reese H. Clark, C Michael Cotten, Michael Cohen-Wolkowiez, P Brian Smith, and P Brian Best Pharmaceuticals for Children Act—Pediatric Trials Network Administrative Core Committee. “Anaerobic antimicrobial therapy after necrotizing enterocolitis in VLBW infants.” Pediatrics 135, no. 1 (January 2015): e117–25. https://doi.org/10.1542/peds.2014-2141.
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  - Laughon, Matthew M., Kim Chantala, Sofia Aliaga, Amy H. Herring, Christoph P. Hornik, Rachel Hughes, Reese H. Clark, and P Brian Smith. “Diuretic exposure in premature infants from 1997 to 2011.” Am J Perinatol 32, no. 1 (January 2015): 49–56. https://doi.org/10.1055/s-0034-1373845.
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  - Samiee-Zafarghandy, Samira, Sudha R. Raman, John N. van den Anker, Kerstin McHutchison, Christoph P. Hornik, Reese H. Clark, P. Brian Smith, and P. Best Pharmaceuticals for Children Act—Pediatric Trials Network Administrative Core Committee. “Safety of milrinone use in neonatal intensive care units.” Early Hum Dev 91, no. 1 (January 2015): 31–35. https://doi.org/10.1016/j.earlhumdev.2014.10.007.
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  - Al-Subu, Awni, Ira Cheifetz, Andrew Lodge, Christoph Hornik, and George Ofori-Amanfo. “CORRELATION BETWEEN INVASIVE AND NON-INVASIVE CARDIAC OUTPUT ASSESSMENT IN HEART TRANSPLANT PATIENTS.” Critical Care Medicine 42, no. 12 (December 1, 2014).
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  - Anderson, Anna W., P Brian Smith, Kristin M. Corey, Kevin D. Hill, Kanecia O. Zimmerman, Reese H. Clark, and Christoph P. Hornik. “Clinical outcomes in very low birth weight infants with major congenital heart defects.” Early Hum Dev 90, no. 12 (December 2014): 791–95. https://doi.org/10.1016/j.earlhumdev.2014.09.006.
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  - Hornik, Christoph P., Kevin D. Hill, Jennifer Li, George Ofori-Amanfo, Reese H. Clark, and P Brian Smith. “Cardiopulmonary Resuscitation in Hospitalized Infants.” Circulation 130 (November 25, 2014).
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  - Plummer, Sarah T., Christoph P. Hornik, Hamilton Baker, Gregory A. Fleming, Susan Foerster, Eric Ferguson, Andrew Glatz, et al. “Maladaptive Aortic Properties after the Norwood Procedure: an Angiographic Analysis of the Pediatric Heart Network Single Ventricle Reconstruction Trial.” Circulation 130 (November 25, 2014).
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  - Hsieh, Emily M., Christoph P. Hornik, Reese H. Clark, Matthew M. Laughon, Daniel K. Benjamin, P Brian Smith, and P Brian Best Pharmaceuticals for Children Act—Pediatric Trials Network. “Medication use in the neonatal intensive care unit.” Am J Perinatol 31, no. 9 (October 2014): 811–21. https://doi.org/10.1055/s-0033-1361933.
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  - Forsha, Daniel, Cameron Slorach, Ching Kit Chen, Elizabeth A. Stephenson, Niels Risum, Christoph Hornik, Galen Wagner, et al. “Classic-pattern dyssynchrony and electrical activation delays in pediatric dilated cardiomyopathy.” J Am Soc Echocardiogr 27, no. 9 (September 2014): 956–64. https://doi.org/10.1016/j.echo.2014.06.014.
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  - Lee, Jan Hau, M Louise Markert, Christoph P. Hornik, Elizabeth A. McCarthy, Stephanie E. Gupton, Ira M. Cheifetz, and David A. Turner. “Clinical course and outcome predictors of critically ill infants with complete DiGeorge anomaly following thymus transplantation.” Pediatr Crit Care Med 15, no. 7 (September 2014): e321–26. https://doi.org/10.1097/PCC.0000000000000219.
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  - Corey, Kristin M., Christoph P. Hornik, Matthew M. Laughon, Kerstin McHutchison, Reese H. Clark, and P Brian Smith. “Frequency of anomalies and hospital outcomes in infants with gastroschisis and omphalocele.” Early Hum Dev 90, no. 8 (August 2014): 421–24. https://doi.org/10.1016/j.earlhumdev.2014.05.006.
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Daniel K. Benjamin, Terry T. Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cumulative radiation exposure and cancer risk estimation in children with heart disease.” Circulation 130, no. 2 (July 8, 2014): 161–67. https://doi.org/10.1161/CIRCULATIONAHA.113.005425.
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  - Bartz, Sarah, Aaloke Mody, Christoph Hornik, James Bain, Michael Muehlbauer, Tonny Kiyimba, Elizabeth Kiboneka, et al. “Severe acute malnutrition in childhood: hormonal and metabolic status at presentation, response to treatment, and predictors of mortality.” J Clin Endocrinol Metab 99, no. 6 (June 2014): 2128–37. https://doi.org/10.1210/jc.2013-4018.
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  - Hornik, Christoph P., Catherine D. Krawczeski, Michael Zappitelli, Kwangik Hong, Heather Thiessen-Philbrook, Prasad Devarajan, Chirag R. Parikh, Uptal D. Patel, and Uptal D. TRIBE-AKI Consortium. “Serum brain natriuretic peptide and risk of acute kidney injury after cardiac operations in children.” Ann Thorac Surg 97, no. 6 (June 2014): 2142–47. https://doi.org/10.1016/j.athoracsur.2014.02.035.
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  - Rajagopal, Sudarshan, Daniel E. Forsha, Niels Risum, Christoph P. Hornik, Abby D. Poms, Terry A. Fortin, Victor F. Tapson, Eric J. Velazquez, Joseph Kisslo, and Zainab Samad. “Comprehensive assessment of right ventricular function in patients with pulmonary hypertension with global longitudinal peak systolic strain derived from multiple right ventricular views.” J Am Soc Echocardiogr 27, no. 6 (June 2014): 657-665.e3. https://doi.org/10.1016/j.echo.2014.02.001.
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  - Bain, J., D. K. Benjamin, C. P. Hornik, R. Clark, and P. B. Smith. “Risk of necrotizing enterocolitis in very-low-birth-weight infants with isolated atrial and ventricular septal defects.” J Perinatol 34, no. 4 (April 2014): 319–21. https://doi.org/10.1038/jp.2013.174.
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  - Beam, Kristyn S., Matthew M. Laughon, Christoph P. Hornik, Michael Cohen-Wolkowiez, Reese H. Clark, Daniel K. Benjamin, and P Brian Smith. “Predictors of positive cerebrospinal fluid cultures in infants with bacteremia.” Pediatr Infect Dis J 33, no. 4 (April 2014): 360–65. https://doi.org/10.1097/INF.0000000000000115.
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  - Laughon, Matthew M., Debbie Avant, Nidhi Tripathi, Christoph P. Hornik, Michael Cohen-Wolkowiez, Reese H. Clark, P Brian Smith, and William Rodriguez. “Drug labeling and exposure in neonates.” Jama Pediatr 168, no. 2 (February 2014): 130–36. https://doi.org/10.1001/jamapediatrics.2013.4208.
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  - Peterson-Carmichael, Stacey L., Margaret Rosenfeld, Simon B. Ascher, Christoph P. Hornik, H. G. M. Arets, Stephanie D. Davis, and Graham L. Hall. “Survey of clinical infant lung function testing practices.” Pediatr Pulmonol 49, no. 2 (February 2014): 126–31. https://doi.org/10.1002/ppul.22807.
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  - Mody, Aaloke, Sarah Bartz, Christoph P. Hornik, Tonny Kiyimba, James Bain, Michael Muehlbauer, Elizabeth Kiboneka, et al. “Effects of HIV infection on the metabolic and hormonal status of children with severe acute malnutrition.” Plos One 9, no. 7 (2014): e102233. https://doi.org/10.1371/journal.pone.0102233.
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  - Trembath, Andrea, Christoph P. Hornik, Reese Clark, P Brian Smith, Julie Daniels, Matthew Laughon, and Matthew Best Pharmaceuticals for Children Act—Pediatric Trials Network. “Comparative effectiveness of surfactant preparations in premature infants.” J Pediatr 163, no. 4 (October 2013): 955-60.e1. https://doi.org/10.1016/j.jpeds.2013.04.053.
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  - Hill, Kevin D., John F. Rhodes, Ranjit Aiyagari, G Hamilton Baker, Lisa Bergersen, Paul J. Chai, Gregory A. Fleming, et al. “Intervention for recoarctation in the single ventricle reconstruction trial: incidence, risk, and outcomes.” Circulation 128, no. 9 (August 27, 2013): 954–61. https://doi.org/10.1161/CIRCULATIONAHA.112.000488.
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  - Crouchley, J. L., P. B. Smith, C. M. Cotten, C. D. Hornik, R. N. Goldberg, J. W. Foreman, and J. L. Wynn. “Effects of low-dose dopamine on urine output in normotensive very low birth weight neonates.” J Perinatol 33, no. 8 (August 2013): 619–21. https://doi.org/10.1038/jp.2013.20.
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  - Hornik, Christoph P., Amy H. Herring, Daniel K. Benjamin, Edmund V. Capparelli, Gregory L. Kearns, John van den Anker, Michael Cohen-Wolkowiez, Reese H. Clark, P Brian Smith, and P Brian Best Pharmaceuticals for Children Act-Pediatric Trials Network. “Adverse events associated with meropenem versus imipenem/cilastatin therapy in a large retrospective cohort of hospitalized infants.” Pediatr Infect Dis J 32, no. 7 (July 2013): 748–53. https://doi.org/10.1097/INF.0b013e31828be70b.
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  - Turner, David A., Richard B. Mink, K Jane Lee, Margaret K. Winkler, Sara L. Ross, Christoph P. Hornik, Jennifer J. Schuette, et al. “Are pediatric critical care medicine fellowships teaching and evaluating communication and professionalism?” Pediatr Crit Care Med 14, no. 5 (June 2013): 454–61. https://doi.org/10.1097/PCC.0b013e31828a746c.
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  - Downey, L. C., D. K. Benjamin, R. H. Clark, K. M. Watt, C. P. Hornik, M. M. Laughon, M. Cohen-Wolkowiez, and P. B. Smith. “Urinary tract infection concordance with positive blood and cerebrospinal fluid cultures in the neonatal intensive care unit.” J Perinatol 33, no. 4 (April 2013): 302–6. https://doi.org/10.1038/jp.2012.111.
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  - Regan, Conor M., Steven Emmanuel, Christoph Hornik, Paul Weinhold, and Moe R. Lim. “Lateral mass versus hybrid construct for cervical laminectomy and fusion.” Orthopedics 36, no. 4 (April 2013): e484–88. https://doi.org/10.3928/01477447-20130327-27.
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  - Bauserman, Melissa S., Matthew M. Laughon, Christoph P. Hornik, P Brian Smith, Daniel K. Benjamin, Reese H. Clark, Cyril Engmann, and Michael Cohen-Wolkowiez. “Group B Streptococcus and Escherichia coli infections in the intensive care nursery in the era of intrapartum antibiotic prophylaxis.” Pediatr Infect Dis J 32, no. 3 (March 2013): 208–12. https://doi.org/10.1097/INF.0b013e318275058a.
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  - Lee, Jan Hau, Christoph P. Hornik, Daniel K. Benjamin, Amy H. Herring, Reese H. Clark, Michael Cohen-Wolkowiez, and P Brian Smith. “Risk factors for invasive candidiasis in infants >1500 g birth weight.” Pediatr Infect Dis J 32, no. 3 (March 2013): 222–26. https://doi.org/10.1097/INF.0b013e3182769603.
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  - Testoni, Daniela, Christoph P. Hornik, P Brian Smith, Daniel K. Benjamin, and Ross E. McKinney. “Sports medicine and ethics.” Am J Bioeth 13, no. 10 (2013): 4–12. https://doi.org/10.1080/15265161.2013.828114.
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  - Hill, Kevin D., John F. Rhodes, Ranjit Aiyagari, G. H. Baker, Lisa Bergersen, Paul J. Chai, Gregory A. Fleming, et al. “Intervention for Re-coarctation in the Single Ventricle Reconstruction Trial: Incidence, Risk and Outcomes.” Circulation 126, no. 21 (November 20, 2012).
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  - Johnson, Jason N., Christoph P. Hornik, Jennifer S. Li, Sara K. Pasquali, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Kevin D. Hill. “Cancer Risk Estimation from Cardiac Catheterization in Children with Heart Disease.” Circulation 126, no. 21 (November 20, 2012).
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  - Srinivasan, Chandra, Christoph P. Hornik, Angela Lloyd, Christine Meliones, Michael P. Carboni, William Darden, and Ronald J. Kanter. “Evaluation of Syncope and its Electrophysiologic Associations in Children and Adolescents: A Pediatric Referral Center Experience.” Circulation 126, no. 21 (November 20, 2012).
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  - Lin, Cheryl B., Christoph P. Hornik, Reese Clark, C Michael Cotten, Daniel K. Benjamin, Michael Cohen-Wolkoweiz, P Brian Smith, and James L. Wynn. “Very low birth weight neonates who survive early-onset sepsis do not have an increased risk of developing late-onset sepsis.” Early Hum Dev 88, no. 11 (November 2012): 905–9. https://doi.org/10.1016/j.earlhumdev.2012.07.009.
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  - Cohen-Wolkowiez, Michael, Kevin M. Watt, Christoph P. Hornik, Daniel K. Benjamin, and P Brian Smith. “Pharmacokinetics and tolerability of single-dose daptomycin in young infants.” Pediatr Infect Dis J 31, no. 9 (September 2012): 935–37. https://doi.org/10.1097/INF.0b013e31825d2fa2.
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  - Hornik, Christoph P., Daniel K. Benjamin, Kristian C. Becker, Jennifer Li, Reese H. Clark, Michael Cohen-Wolkowiez, and P Brian Smith. “Use of the complete blood cell count in early-onset neonatal sepsis.” Pediatr Infect Dis J 31, no. 8 (August 2012): 799–802. https://doi.org/10.1097/INF.0b013e318256905c.
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  - Hornik, Christoph P., Daniel K. Benjamin, Kristian C. Becker, Jennifer Li, Reese H. Clark, Michael Cohen-Wolkowiez, and P Brian Smith. “Use of the complete blood cell count in late-onset neonatal sepsis.” Pediatr Infect Dis J 31, no. 8 (August 2012): 803–7. https://doi.org/10.1097/INF.0b013e31825691e4.
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  - Hornik, Christoph P., Xia He, Jeffrey P. Jacobs, Jennifer S. Li, Robert D. B. Jaquiss, Marshall L. Jacobs, Sean M. O’Brien, Karl Welke, Eric D. Peterson, and Sara K. Pasquali. “Relative impact of surgeon and center volume on early mortality after the Norwood operation.” Ann Thorac Surg 93, no. 6 (June 2012): 1992–97. https://doi.org/10.1016/j.athoracsur.2012.01.107.
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  - Hornik, C. P., P. Fort, R. H. Clark, K. Watt, D. K. Benjamin, P. B. Smith, P. Manzoni, E. Jacqz-Aigrain, F. Kaguelidou, and M. Cohen-Wolkowiez. “Early and late onset sepsis in very-low-birth-weight infants from a large group of neonatal intensive care units.” Early Hum Dev 88 Suppl 2 (May 2012): S69–74. https://doi.org/10.1016/S0378-3782(12)70019-1.
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  - Pasquali, Sara K., Jeffrey P. Jacobs, Xia He, Christoph P. Hornik, Robert D. B. Jaquiss, Marshall L. Jacobs, Sean M. O’Brien, Eric D. Peterson, and Jennifer S. Li. “The complex relationship between center volume and outcome in patients undergoing the Norwood operation.” Ann Thorac Surg 93, no. 5 (May 2012): 1556–62. https://doi.org/10.1016/j.athoracsur.2011.07.081.
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  - Hornik, Christoph P., and David A. Turner. “High-flow nasal cannula for neonatal respiratory distress: is it enough?” Respir Care 56, no. 12 (December 2011): 1972–74. https://doi.org/10.4187/respcare.01645.
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  - Hornik, Christoph P., Xia He, Jeffrey P. Jacobs, Jennifer S. Li, Robert D. B. Jaquiss, Marshall L. Jacobs, Sean M. O’Brien, Eric D. Peterson, and Sara K. Pasquali. “Complications after the Norwood operation: an analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database.” Ann Thorac Surg 92, no. 5 (November 2011): 1734–40. https://doi.org/10.1016/j.athoracsur.2011.05.100.
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  - Hornik, Christoph P., Michael J. Campbell, Michael P. Carboni, Andrew J. Lodge, John F. Rhodes, and Ronald J. Kanter. “Preoperative diagnosis of long QT syndrome in an infant with tetralogy of Fallot.” Pediatr Cardiol 32, no. 6 (August 2011): 834–38. https://doi.org/10.1007/s00246-011-9957-0.
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  - Hornik, Christoph P., Mary E. Hartman, M Louise Markert, Andrew J. Lodge, Ira M. Cheifetz, and David A. Turner. “Successful extracorporeal membrane oxygenation for respiratory failure in an infant with DiGeorge anomaly, following thymus transplantation.” Respir Care 56, no. 6 (June 2011): 866–70. https://doi.org/10.4187/respcare.01051.
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  - Piper, Lauren, P Brian Smith, Christoph P. Hornik, Ira M. Cheifetz, Jeffrey S. Barrett, Ganesh Moorthy, William W. Hope, Kelly C. Wade, Michael Cohen-Wolkowiez, and Daniel K. Benjamin. “Fluconazole loading dose pharmacokinetics and safety in infants.” Pediatr Infect Dis J 30, no. 5 (May 2011): 375–78. https://doi.org/10.1097/INF.0b013e318202cbb3.
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  - Malcolm, W. F., C. Hornik, A. Evans, P. B. Smith, and C. M. Cotten. “Vocal fold paralysis following surgical ductal closure in extremely low birth weight infants: a case series of feeding and respiratory complications.” J Perinatol 28, no. 11 (November 2008): 782–85. https://doi.org/10.1038/jp.2008.109.
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  - Hornik, Christoph, Kewal Krishan, Faisal Yusuf, Martin Scaal, and Beate Brand-Saberi. “cDermo-1 misexpression induces dense dermis, feathers, and scales.” Dev Biol 277, no. 1 (January 1, 2005): 42–50. https://doi.org/10.1016/j.ydbio.2004.08.050.
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  - Hornik, Christoph, Beate Brand-Saberi, Stefan Rudloff, Bodo Christ, and Ernst-Martin Füchtbauer. “Twist is an integrator of SHH, FGF, and BMP signaling.” Anat Embryol (Berl) 209, no. 1 (November 2004): 31–39. https://doi.org/10.1007/s00429-004-0412-3.
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  - Hornik, Christoph. “The role of cDermo-1 and cTwist in the avian embryo.” Ann Anat 186, no. 4 (August 2004): 291–92. https://doi.org/10.1016/S0940-9602(04)80042-6.
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  - Franke, Thomas F., Christoph P. Hornik, Lisa Segev, Grigoriy A. Shostak, and Chizuru Sugimoto. “PI3K/Akt and apoptosis: size matters.” Oncogene 22, no. 56 (December 8, 2003): 8983–98. https://doi.org/10.1038/sj.onc.1207115.
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  - Scaal, Martin, Felicitas Pröls, Ernst Martin Füchtbauer, Ketan Patel, Christoph Hornik, Thomas Köhler, Bodo Christ, and Beate Brand-Saberi. “BMPs induce dermal markers and ectopic feather tracts.” Mech Dev 110, no. 1–2 (January 2002): 51–60. https://doi.org/10.1016/s0925-4773(01)00552-4.
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- Book Sections
  - Kumar, K. R., R. E. Kirsch, and C. P. Hornik. “Cardiovascular physiology for intensivists.” In Critical Heart Disease in Infants and Children, 111-133.e5, 2018. https://doi.org/10.1016/B978-1-4557-0760-7.00013-9.
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- Conference Papers
  - Gerhart, Jacqueline G., Kevin M. Watt, Andrea Edginton, Kelly C. Wade, Sara N. Salerno, Daniel K. Benjamin, P Brian Smith, et al. “Physiologically-Based Pharmacokinetic Modeling of Fluconazole Using Plasma and Cerebrospinal Fluid Samples From Preterm and Term Infants.” In Cpt Pharmacometrics Syst Pharmacol, 8:500–510, 2019. https://doi.org/10.1002/psp4.12414.
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  - Koeberl, Dwight, Laura Case, Edward C. Smith, Yanzhen Li, Crista Walters, Christoph Hornik, Beth Thurberg, Deeksha Bali, Nenad Bursac, and Priya S. Kishnani. “Correction of biochemical abnormalities and gene expression associated with improved muscle function in a phase I/II clinical trial of clenbuterol in Pompe disease patients stably treated with ERT.” In Molecular Genetics and Metabolism, 123:S79–80. Elsevier BV, 2018. https://doi.org/10.1016/j.ymgme.2017.12.202.
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  - Schwartz, Stephanie, Julia Salinaro, Karan Kumar, Desiree Bonadonna, Christoph Hornik, David Turner, and Andrew Lodge. “244.” In Critical Care Medicine, 46:104–104. Ovid Technologies (Wolters Kluwer Health), 2018. https://doi.org/10.1097/01.ccm.0000528263.29456.0c.
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  - Sherwin, Jennifer, Miracle Thomas, Elizabeth Thompson, Chi Hornik, Laura Sullivan, Andrew Lodge, and Christoph Hornik. “233.” In Critical Care Medicine, 46:99–99. Ovid Technologies (Wolters Kluwer Health), 2018. https://doi.org/10.1097/01.ccm.0000528252.57219.30.
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  - Hill, Kevin D., Sean O’Brien, H Scott Baldwin, David Bichel, Christoph Hornik, Jeffrey Jacobs, Marshall Jacobs, et al. “Overcoming Underpowering: Simulation Study to Evaluate an STS Global Rank Endpoint for Trials in Congenital Heart Surgery.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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  - Wallace, Amelia S., Marshall L. Jacobs, Christoph P. Hornik, John M. Costello, Gregory A. Fleming, Jeffrey P. Jacobs, Robert D. Jaquiss, Bryan H. Goldstein, Reid C. Chamberlain, and Kevin D. Hill. “Post-operative Cardiac Catheterization in Children Undergoing Congenital Heart Surgery: An Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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  - O’Byrne, Michael L., Sunghee Kim, Christoph Hornik, Babatunde Yerokun, Roland Matsouaka, Jeffrey Jacobs, Marshall Jacobs, and Richard Jonas. “EFFECT OF OBESITY AND UNDERWEIGHT STATUS ON PERIOPERATIVE OUTCOMES IN PATIENTS WITH CONGENITAL HEART DISEASE: AN ANALYSIS OF DATA FROM THE SOCIETY OF THORACIC SURGEONS CONGENITAL HEART SURGERY DATABASE.” In Journal of the American College of Cardiology, 69:574–574. ELSEVIER SCIENCE INC, 2017.
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  - Gehlbach, J. A., A. G. Miller, C. P. Hornik, and I. M. Cheifetz. “Deadspace To Tidal Volume Ratio As A Predictor Of Extubation Success.” In American Journal of Respiratory and Critical Care Medicine, Vol. 195. AMER THORACIC SOC, 2017.
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  - Chamberlain, reid, jon Pelletier, sarah Blanchard, cp Hornik, kd Hill, and M. J. Campbell. “Evaluating Appropriate Use of Pediatric Echocardiogram for Chest Pain in Outpatient Clinics.” In Circulation, Vol. 134:A18843. American Heart Association, 2016.
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  - Li, Jennifer S., Kevin D. Hill, Christoph P. Hornik, Richard A. Krasuski, Piers C. Barker, Robert D. Jaquiss, and Michael J. Campbell. “Utility of Multi-modal Imaging in the Diagnosis of Pulmonary Valve Endocarditis.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Guptill, Jeff, Rachel Greenberg, Chiara Mellon, Huali Wu, Daniel Gonzalez, Lawrence Ku, Kevin Hill, et al. “Narrow Therapeutic Index Classification of Antiepileptic Drugs Using a Comprehensive Literature Search.” In Neurology, Vol. 86. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Guptill, Jeff, Rachel Greenberg, Chiara Melloni, Huali Wu, Daniel Gonzalez, Lawrence Ku, Kevin Hill, et al. “Narrow Therapeutic Index Classification of Antiepileptic Drugs Using a Comprehensive Literature Search.” In Neurology, Vol. 86. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Bourguet-Vincent, A., S. Hupp, S. Martin, C. Hornik, and C. Ozment. “Effect Of Anti-Factor Xa And Aptt Levels On Mortality In Pediatric Extracorporeal Membrane Oxygenation.” In American Journal of Respiratory and Critical Care Medicine, Vol. 193. AMER THORACIC SOC, 2016.
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  - Hill, Kevin D., Heather T. Henderson, Christoph P. Hornik, and Jennifer S. Li. “Paediatric cardiovascular clinical trials: an analysis of ClinicalTrials.gov and the Food and Drug Administration Pediatric Drug Labeling Database.” In Cardiol Young, 25 Suppl 2:172–80, 2015. https://doi.org/10.1017/S1047951115000980.
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  - Chu, Patricia Y., Christoph P. Hornik, Jennifer S. Li, Michael J. Campbell, and Kevin D. Hill. “National Trends in RSV Hospitalizations in Children With Hemodynamically Significant Heart Disease, 1997-2009.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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  - Hornik, Christoph P., Patricia Y. Chu, Jennifer S. Li, Reese H. Clark, Phillip Brian Smith, and Kevin D. Hill. “Comparative effectiveness of digoxin and propranolol for supraventricular tachycardia in infants.” In Pediatr Crit Care Med, 15:839–45, 2014. https://doi.org/10.1097/PCC.0000000000000229.
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  - Hornik, Christoph P., Robert Jaquiss, Jeffrey Jacobs, Marshall Jacobs, Sara Pasquali, Amelia Wallace, and Kevin Hill. “MAJOR ADVERSE CARDIAC EVENTS IN CHILDREN WITH WILLIAMS BEUREN SYNDROME UNDERGOING SURGERY: AN ANALYSIS OF THE SOCIETY OF THORACIC SURGEONS CONGENITAL HEART SURGERY DATABASE.” In Journal of the American College of Cardiology, 63:A588–A588. Elsevier BV, 2014. https://doi.org/10.1016/s0735-1097(14)60588-x.
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  - Bishop, Robert, Jon Meliones, George Ofori-Amanfo, Christoph Hornik, and Piers Barker. “339.” In Critical Care Medicine, 41:A80–A80. Ovid Technologies (Wolters Kluwer Health), 2013. https://doi.org/10.1097/01.ccm.0000439483.07162.05.
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  - Koo, Jean, Christoph Hornik, Jon Meliones, Robert Jaquiss, and George Ofori-Amanfo. “280.” In Critical Care Medicine, 41:A64–65. Ovid Technologies (Wolters Kluwer Health), 2013. https://doi.org/10.1097/01.ccm.0000439426.02837.0c.
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  - Forsha, Daniel, Cameron Slorach, Ching Kit Chen, Niels Risum, Christoph Hornik, Peter Sogaard, Luc Mertens, Piers Barker, Joseph Kisslo, and Mark K. Friedberg. “Classic Pattern Dyssynchrony is Associated With Left Bundle Branch Block in Pediatric Dilated Cardiomyopathy.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Hill, Kevin D., Christoph P. Hornik, Jennifer S. Li, Terry Yoshizumi, Robert E. Reiman, Donald P. Frush, and Jason Johnson. “Radiation Exposure and Estimated Lifetime Attributable Risk of Cancer From Cardiac Catheterization in Children.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Plummer, Sarah T., Ravi Kankotia, Christoph Hornik, Andrew Lodge, Jennifer Li, and Kevin Hill. “Clinical Utility of Routine pre-Fontan Invasive Hemodynamic Assessment for Surgical Risk Stratification.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Lee, J. H., M. L. Markert, C. P. Hornik, E. A. McCarthy, S. E. Gupton, I. M. Cheifetz, and D. A. Turner. “SEPSIS INCREASES MORBIDITY OF CRITICALLY ILL INFANTS WITH COMPLETE DIGEORGE ANOMALY TREATED WITH THYMUS TRANSPLANTATION.” In Intensive Care Medicine, 39:S412–S412. SPRINGER, 2013.
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  - Lee, Jan Hau, Louise Markert, Christoph Hornik, Elizabeth McCarthy, Stephanie Gupton, Ira Cheifetz, and David Turner. “CRITICAL ILLNESS IN INFANTS WITH COMPLETE DIGEORGE ANOMALY TREATED WITH THYMUS TRANSPLANTATION.” In Critical Care Medicine, 40:U189–U189. LIPPINCOTT WILLIAMS & WILKINS, 2012.
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  - Hornik, Christoph P., Jeffrey P. Jacobs, Xia He, Audra Hodges, Robert D. B. Jaquiss, Marshall L. Jacobs, Jennifer S. Li, Sean M. O’Brien, Eric D. Peterson, and Sara K. Pasquali. “PREVALENCE AND MORTALITY RISK ASSOCIATED WITH POST-OPERATIVE COMPLICATIONS FOLLOWING THE NORWOOD OPERATION: ANALYSIS OF A NATIONAL CLINICAL DATABASE.” In Journal of the American College of Cardiology, 57:E449–E449. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60449-x.
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  - Pasquali, Sara K., Jennifer S. Li, Xia He, Audra Hodges, Christoph P. Hornik, Robert D. B. Jaquiss, Marshall L. Jacobs, Sean M. O’Brien, Eric D. Peterson, and Jeffrey P. Jacobs. “PATIENT RISK STATUS, CENTER VOLUME AND OUTCOME FOLLOWING THE NORWOOD OPERATION.” In Journal of the American College of Cardiology, 57:E406–E406. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60406-3.
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  - Hornik, C., K. Krishan, and B. Brand-Saberi. “The function of cDermo-1 in skin development.” In European Journal of Cell Biology, 82:120–21. URBAN & FISCHER VERLAG, 2003.
    Link to Item
  - Barker, P., G. Tatum, A. French, M. J. Campbell, A. Milazzo, M. Camitta, C. Hornik, and S. Miller. “Implementation of a Perinatal Family Bonding Program for Infants with Congenital Heart Disease,” n.d.
  - Chu, P., C. Hornik, J. S. Li, M. J. Campbell, and K. D. Hill. “National Trends in RSV Hospitalization in Children with Hemodynamically Significant Heart Disease, 1997-2009,” n.d.

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