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Christoph Paul Vincent Hornik

Samuel L. Katz Distinguished Professor of Pediatrics
Pediatrics, Critical Care Medicine
DCRI PO Box 17969, Durham, NC 27715
Dept of Pediatrics, Durham, NC 27710

Current Appointments & Affiliations


Samuel L. Katz Distinguished Professor of Pediatrics · 2024 - Present Pediatrics, Critical Care Medicine, Pediatrics
Professor of Pediatrics · 2023 - Present Pediatrics, Critical Care Medicine, Pediatrics
Chief, Division of Quantitative Sciences · 2018 - Present Pediatrics, Clinical Science Departments
Vice-Chair for Research in the Department of Pediatrics · 2022 - Present Pediatrics, Clinical Science Departments
Membership in the Duke Clinical Research Institute · 2013 - Present Duke Clinical Research Institute, Institutes and Centers

In the News


Published March 19, 2024
Duke Awards 32 New Distinguished Professorships for 2024
Published October 7, 2022
New DCRI Center Targets Ending Opioid Addiction
Published September 16, 2022
No More Guessing on the Right Dosage for Children

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Recent Publications


An Adult Population Pharmacokinetic Model to Simulate Subcutaneous Administration of a Fixed Dose of Furosemide in Adolescents with Heart Failure and Volume Overload.

Journal Article Clin Pharmacokinet · June 2025 BACKGROUND: Subcutaneous furosemide administered with the On-Body Infusor could be useful in children with heart failure (HF) and congestion due to volume overload, but the appropriate dosing regimen is unknown. OBJECTIVE: This study aimed to develop a pop ... Full text Link to item Cite

Going Places: An Active Transportation Intervention to Increase Youth Physical Activity, Durham, North Carolina, 2023-2024.

Journal Article Am J Public Health · May 2025 Routine youth physical activity (PA) fosters healthy habits and lasting cardiometabolic benefits into adulthood; however, significant disparities in PA persist by race, ethnicity, and income. Active transportation is an optimal intervention target to promo ... Full text Link to item Cite

Breast milk delivery of an engineered dimeric IgA protects neonates against rotavirus.

Journal Article Mucosal Immunol · April 2025 Dimeric IgA (dIgA) is the dominant antibody in many mucosal tissues. It is actively transported onto mucosal surfaces as secretory IgA (sIgA) which plays an integral role in protection against enteric pathogens, particularly in young children. Therapeutic ... Full text Link to item Cite
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Recent Grants


Duke University Maternal-Fetal Medicine Units (MFMU) Network Clinical Center

ResearchCollaborating Investigator · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2023 - 2030

Real-world Data Enables Pharmacokinetic/Pharmacodynamic Drug Dosing in Critically Ill Children

ResearchMentor · Awarded by National Institutes of Health · 2025 - 2029

DCRI D-COHRe Partnership for Innovation, Improved Access, and Operational Capability for Decentralized Clinical Trials of Medical Countermeasures in Public Health Emergencies

ResearchPrincipal Investigator · Awarded by Biomedical Advanced Research and Development Authority · 2024 - 2029

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Education, Training & Certifications


University of North Carolina, Chapel Hill · 2019 Ph.D.
University of North Carolina, Chapel Hill · 2012 M.P.H.
Albert Ludwigs University of Freiburg (Germany) · 2005 M.D.