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Christopher Lee Holley

Associate Professor of Medicine
Medicine, Cardiology
DUMC Box 102149, 2301 Erwin Road, Durham, NC 27710
213 Research Drive, CARL Bldg Rm 128, Durham, NC 27710

Scholarly Works - Conferences


SNORD3A: a new possible circulating biomarker of human heart failure

Conference European Heart Journal · October 28, 2024 AbstractBackgroundHeart failure (HF) is a complex clinical syndrome and the leading cause of mortality, morbidity and hospitalization ... Full text Cite

Metabolomic profiling during ex situ normothermic perfusion before heart transplantation defines patterns of substrate utilization and correlates with markers of allograft injury.

Conference J Heart Lung Transplant · May 2024 BACKGROUND: Cardiac metabolism is altered in heart failure and ischemia-reperfusion injury states. We hypothesized that metabolomic profiling during ex situ normothermic perfusion before heart transplantation (HT) would lend insight into myocardial substra ... Full text Link to item Cite

527 CIRCULATING SMALL NUCLEOLAR RNA SNORD3A AS A NOVEL PREDICTIVE BIOMARKERS OF HEART FAILURE

Conference European Heart Journal Supplements · December 15, 2022 AbstractBackgroundDespite optimal therapy, heart failure (HF) remains a relentless and deadly disease. Given the relative inaccessibil ... Full text Cite

183 Small nucleolar RNA SNORD3A: a potential new biomarker and molecular player in heart failure

Conference European Heart Journal Supplements · December 8, 2021 AbstractAimsDespite optimal therapy, heart failure (HF) remains a relentless and deadly disease. Given the relative inaccessibility of ... Full text Cite

Abstract 378: Physiologic Role of Rpl13a SnoRNAs in Cell Size Regulation

Conference Circulation Research · July 31, 2020 Objectives: Box C/D small nucleolar RNAs (snoRNA) are a multifunctional family of ncRNAs that play a critical role in guiding 2'- O -methylation (Nm) ... Full text Cite

Pre-Formed Donor-Specific Antibodies Impact Long Term Survival of Heart Transplants

Conference The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · April 1, 2020 PURPOSE: We previously reported that heart transplant (HTx) recipients with pre-formed, anti-HLA antibodies at low titer had one-year survival that was comparable to patients without any anti-HLA antibodies. As a result, we defined unacceptable HLA antigen ... Full text Cite