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Christopher Mosher

Assistant Professor of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
DCRI - Durham Centre Building, 300 West Morgan St., Office 833, Durham, NC 27701

Overview


As a physician-investigator my research focus is to identify new therapies and strategies to improve outcomes in persons living with Chronic Obstructive Pulmonary Disease (COPD). In pursuit of this goal, I've focused my research in the following areas: 1) clinical trial investigation of novel COPD therapeutics, 2) investigating mechanisms responsible for the treatment response to pulmonary rehabilitation through an aging lens, and 3) risk of cardiovascular disease in COPD. 

Current Appointments & Affiliations


Assistant Professor of Medicine · 2023 - Present Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine
Member in the Duke Clinical Research Institute · 2021 - Present Duke Clinical Research Institute, Institutes and Centers

In the News


Published May 15, 2025
Point-of-Care Testing Safely Reduces Antibiotic Use in COPD Exacerbations
Published June 27, 2024
FDA approves new COPD drug developed by firm in Raleigh. First new treatment in a decade.
Published June 26, 2024
Q&A: Pulmonary Rehabilitation Linked to Significant Cost Savings in COPD Care

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Recent Publications


Risk of Atherosclerotic Cardiovascular Disease After Chronic Obstructive Pulmonary Disease Hospitalization among Primary and Secondary Prevention Older Adults.

Journal Article J Am Heart Assoc · January 21, 2025 BACKGROUND: Meta-analyses have suggested that the risk of cardiovascular disease events is significantly higher after a chronic obstructive pulmonary disease (COPD) exacerbation, but the populations at highest risk have not been well characterized to date. ... Full text Link to item Cite

Feasibility, Usability, and Pilot Efficacy Study of a Software-Enabled, Virtual Pulmonary Rehabilitation with Remote Therapeutic Monitoring.

Journal Article Int J Chron Obstruct Pulmon Dis · 2025 OBJECTIVE: Fewer than 3% of adults with Chronic Obstructive Pulmonary Disease (COPD) attend in-person, center-based pulmonary rehabilitation (PR) despite demonstrated health benefits and reduction in mortality. This study evaluated the feasibility and usab ... Full text Link to item Cite
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Recent Grants


RofLumilast or Azithromycin to preveNt COPD Exacerbations (RELIANCE) - REIMBURSEABLE

ResearchPrincipal Investigator · Awarded by University of Illinois at Chicago · 2017 - 2027

COPD Pulmonary Rehab GEMSSTAR Award

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2023 - 2026

Snake in the Grass: Cardiovascular Outcome Risks After AECOPD (COBRA)

ResearchPrincipal Investigator · Awarded by American Lung Association · 2022 - 2024

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Education, Training & Certifications


Duke University · 2021 M.H.S.
Indiana University, School of Medicine · 2014 M.D.