Claude Lebernian Hughes Jr.

Book section · November 21, 2016 Translational biomedical research seeks to move laboratory findings based on models (in silico, in vitro, and in vivo) into human clinical trials to more expeditiously develop specific therapeutics, and then back again to the laboratory to inform future di ... Full text Cite

The opportunity to translate developmental toxicology into a therapeutic discipline

Book section · January 1, 2016 Since presentation of our view of translational developmental toxicology in 2013, numerous investigations from a wide range of approaches have added to the evidence underlying our core premise; namely that as the potential adverse developmental effects fro ... Full text Cite

Ligand-mediated toxicology: Characterization and translational prospects

Book section · January 1, 2016 In biochemistry a ligand is a molecule that binds to a receptor or other biomolecule that forms a complex and produces a biological effect. We live in a world of exposure to exogenous ligands and there are three long-established strands of biological resea ... Full text Cite

Cigarette smoking and ovarian function

Book section · January 1, 2013 The global prevalence of infertility is estimated to be 9% [1] and between 50 and 80 million people worldwide are infertile [2]. Advanced age, diet, prescription medication use, preexisting health status, and infections are among the known risk factors for ... Full text Cite