Scholars@Duke
Leonor Corsino

Leonor Corsino

Professor of Medicine
Medicine, Endocrinology, Metabolism, and Nutrition
leonor.corsinonunez@duke.edu
Department of Medicine, Box 3451, Durham, NC 27710

Featured Works

Greater weight loss with increasing age in the weight loss maintenance trial.

Journal article Obesity (Silver Spring) · January 2014 Featured Publication OBJECTIVE: To determine the effect of age on weight loss and weight loss maintenance in participants in the Weight Loss Maintenance trial (WLM). DESIGN AND METHODS: Secondary analysis of a randomized controlled trial of overweight/obese adults with CVD ris ... Full text Link to item Cite

Recruiting young adults into a weight loss trial: report of protocol development and recruitment results.

Journal article Contemp Clin Trials · July 2013 Featured Publication Obesity has spread to all segments of the U.S. population. Young adults, aged 18-35 years, are rarely represented in clinical weight loss trials. We conducted a qualitative study to identify factors that may facilitate recruitment of young adults into a we ... Full text Open Access Link to item Cite

Family diabetes matters: a view from the other side.

Journal article J Gen Intern Med · March 2013 Featured Publication BACKGROUND: Typically, chronic disease self-management happens in a family context, and for African American adults living with diabetes, family seems to matter in self-management processes. Many qualitative studies describe family diabetes interactions fr ... Full text Link to item Cite

Achieving health for a lifetime: a community engagement assessment focusing on school-age children to decrease obesity in Durham, North Carolina.

Journal article N C Med J · 2013 Featured Publication BACKGROUND: Obesity is a prominent problem in the United States and in North Carolina. One way of combating it is with community-engaged interventions that foster collaboration between health-oriented organizations and community residents. PURPOSE: Our pur ... Link to item Cite

Predictors of long-term weight loss in adults with modest initial weight loss, by sex and race.

Journal article Obesity (Silver Spring) · September 2012 Featured Publication Effective weight management interventions could reduce race-sex disparities in cardiovascular disease (CVD), yet little is known about factors associated with successful weight loss maintenance in race-sex subgroups. In the Weight Loss Maintenance trial (W ... Full text Link to item Cite

The Latino Health Project: pilot testing a culturally adapted behavioral weight loss intervention in obese and overweight Latino adults.

Journal article Ethn Dis · 2012 Featured Publication OBJECTIVE: To pilot test a culturally adapted behavioral weight loss intervention in obese and overweight Latino adults. DESIGN: Pilot study. SETTING: Latino community organization in Durham, North Carolina. PARTICIPANTS: Overweight and obese, self-identif ... Open Access Link to item Cite

Influence of change in aerobic fitness and weight on prevalence of metabolic syndrome.

Journal article Prev Chronic Dis · 2012 Featured Publication INTRODUCTION: The metabolic syndrome is the clustering of several cardiometabolic risk factors that can lead to the development of coronary heart disease and type 2 diabetes. We evaluated whether a change in aerobic fitness resulting from a lifestyle inter ... Full text Link to item Cite

Physician characteristics as predictors of blood pressure control in patients enrolled in the hypertension improvement project (HIP).

Journal article J Clin Hypertens (Greenwich) · February 2011 Featured Publication The authors sought to examine the relationship between physician characteristics and patient blood pressure (BP) in participants enrolled in the Hypertension Improvement Project (HIP). In this cross-sectional study using baseline data of HIP participants, ... Full text Link to item Cite

Hypertension Improvement Project (HIP) Latino: results of a pilot study of lifestyle intervention for lowering blood pressure in Latino adults.

Journal article Ethn Health · June 2010 Featured Publication OBJECTIVES: To assess the feasibility of a culturally tailored behavioral intervention for improving hypertension-related health behaviors in Hispanic/Latino adults. DESIGN: Feasibility pilot study in a community health center and a Latino organization in ... Full text Open Access Link to item Cite

Dipeptidyl peptidase-4 inhibitors in the management of type 2 diabetes: safety, tolerability, and efficacy.

Journal article Drug Healthc Patient Saf · 2010 Featured Publication Although glycemic control is an important and effective way to prevent and minimize the worsening of diabetes-related complications, type 2 diabetes is a progressive disease which often proves difficult to manage. Most affected patients will eventually req ... Full text Link to item Cite

A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation.

Journal article Sci Transl Med · October 7, 2009 Featured Publication About 40% of the therapeutic agents in use today exert their effects through seven-transmembrane receptors (7TMRs). When activated by ligands, these receptors trigger two pathways that independently transduce signals to the cell: one through heterotrimeric ... Full text Link to item Cite

Patient characteristics associated with receipt of lifestyle behavior advice.

Journal article N C Med J · 2009 Featured Publication BACKGROUND: Lifestyle behaviors such as reducing weight if overweight or obese, reducing salt intake, exercising, reducing alcohol intake, quitting smoking, and eating a healthy diet are related to the prevention and control of chronic diseases. However th ... Link to item Cite