Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., University of California at Santa Cruz 2010
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Pollen, AA, Bhaduri, A, Andrews, MG, Nowakowski, TJ, Meyerson, OS, Mostajo-Radji, MA, Di Lullo, E, Alvarado, B, Bedolli, M, Dougherty, ML, Fiddes, IT, Kronenberg, ZN, Shuga, J, Leyrat, AA, West, JA, Bershteyn, M, Lowe, CB, Pavlovic, BJ, Salama, SR, Haussler, D, Eichler, EE, and Kriegstein, AR. "Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution." Cell 176, no. 4 (February 2019): 743-756.e17.  Full Text
    • Song, JHT, Lowe, CB, and Kingsley, DM. "Characterization of a Human-Specific Tandem Repeat Associated with Bipolar Disorder and Schizophrenia." American Journal of Human Genetics 103, no. 3 (September 2018): 421-430.  Full Text
    • Lowe, CB, Sanchez-Luege, N, Howes, TR, Brady, SD, Daugherty, RR, Jones, FC, Bell, MA, and Kingsley, DM. "Detecting differential copy number variation between groups of samples." Genome Research 28, no. 2 (February 2018): 256-265.  Full Text  Open Access Copy
    • Lowe, CB, Clarke, JA, Baker, AJ, Haussler, D, and Edwards, SV. "Feather development genes and associated regulatory innovation predate the origin of Dinosauria." Molecular Biology and Evolution 32, no. 1 (January 2015): 23-28.  Full Text  Open Access Copy
    • Lowe, CB, and Haussler, D. "29 mammalian genomes reveal novel exaptations of mobile elements for likely regulatory functions in the human genome." Plos One 7, no. 8 (January 2012): e43128-null.  Full Text  Open Access Copy
    • Lowe, CB. "Three periods of regulatory innovation during vertebrate evolution (Science (1019))." Science 334, no. 6057 (November 11, 2011): 761-null.  Full Text
    • Lindblad-Toh, K, Garber, M, Zuk, O, Lin, MF, Parker, BJ, Washietl, S, Kheradpour, P, Ernst, J, Jordan, G, Mauceli, E, Ward, LD, Lowe, CB, Holloway, AK, Clamp, M, Gnerre, S, Alföldi, J, Beal, K, Chang, J, Clawson, H, Cuff, J, Di Palma, F, Fitzgerald, S, Flicek, P, Guttman, M, Hubisz, MJ, Jaffe, DB, Jungreis, I, Kent, WJ, Kostka, D, Lara, M, Martins, AL, Massingham, T, Moltke, I, Raney, BJ, Rasmussen, MD, Robinson, J, Stark, A, Vilella, AJ, Wen, J, Xie, X, Zody, MC, Broad Institute Sequencing Platform and Whole Genome Assembly Team, , Baldwin, J, Bloom, T, Chin, CW, Heiman, D, Nicol, R, Nusbaum, C, Young, S, Wilkinson, J, Worley, KC, Kovar, CL, Muzny, DM, Gibbs, RA, Baylor College of Medicine Human Genome Sequencing Center Sequencing Team, , Cree, A, Dihn, HH, Fowler, G, Jhangiani, S, Joshi, V, Lee, S, Lewis, LR, Nazareth, LV, Okwuonu, G, Santibanez, J, Warren, WC, Mardis, ER, Weinstock, GM, Wilson, RK, Genome Institute at Washington University, , Delehaunty, K, Dooling, D, Fronik, C, Fulton, L, Fulton, B, Graves, T, Minx, P, Sodergren, E, Birney, E, Margulies, EH, Herrero, J, Green, ED, Haussler, D, Siepel, A, Goldman, N, Pollard, KS, Pedersen, JS, Lander, ES, and Kellis, M. "A high-resolution map of human evolutionary constraint using 29 mammals." Nature 478, no. 7370 (October 12, 2011): 476-482.  Full Text  Open Access Copy
    • Alföldi, J, Di Palma, F, Grabherr, M, Williams, C, Kong, L, Mauceli, E, Russell, P, Lowe, CB, Glor, RE, Jaffe, JD, Ray, DA, Boissinot, S, Shedlock, AM, Botka, C, Castoe, TA, Colbourne, JK, Fujita, MK, Moreno, RG, ten Hallers, BF, Haussler, D, Heger, A, Heiman, D, Janes, DE, Johnson, J, de Jong, PJ, Koriabine, MY, Lara, M, Novick, PA, Organ, CL, Peach, SE, Poe, S, Pollock, DD, de Queiroz, K, Sanger, T, Searle, S, Smith, JD, Smith, Z, Swofford, R, Turner-Maier, J, Wade, J, Young, S, Zadissa, A, Edwards, SV, Glenn, TC, Schneider, CJ, Losos, JB, Lander, ES, Breen, M, Ponting, CP, and Lindblad-Toh, K. "The genome of the green anole lizard and a comparative analysis with birds and mammals." Nature 477, no. 7366 (August 31, 2011): 587-591.  Full Text  Open Access Copy
    • Lowe, CB, Kellis, M, Siepel, A, Raney, BJ, Clamp, M, Salama, SR, Kingsley, DM, Lindblad-Toh, K, and Haussler, D. "Three periods of regulatory innovation during vertebrate evolution." Science (New York, N.Y.) 333, no. 6045 (August 2011): 1019-1024.  Full Text  Open Access Copy
    • Lowe, CB, Bejerano, G, Salama, SR, and Haussler, D. "Endangered species hold clues to human evolution." The Journal of Heredity 101, no. 4 (July 2010): 437-447.  Full Text  Open Access Copy
    • McLean, CY, Bristor, D, Hiller, M, Clarke, SL, Schaar, BT, Lowe, CB, Wenger, AM, and Bejerano, G. "GREAT improves functional interpretation of cis-regulatory regions." Nature Biotechnology 28, no. 5 (May 2, 2010): 495-501.  Full Text  Open Access Copy
    • Zhu, J, Sanborn, JZ, Diekhans, M, Lowe, CB, Pringle, TH, and Haussler, D. "Comparative genomics search for losses of long-established genes on the human lineage." Plos Computational Biology 3, no. 12 (December 2007): e247-null.  Full Text
    • Wang, T, Zeng, J, Lowe, CB, Sellers, RG, Salama, SR, Yang, M, Burgess, SM, Brachmann, RK, and Haussler, D. "Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53." Proceedings of the National Academy of Sciences of the United States of America 104, no. 47 (November 14, 2007): 18613-18618.  Full Text  Open Access Copy
    • Lowe, CB, Bejerano, G, and Haussler, D. "Thousands of human mobile element fragments undergo strong purifying selection near developmental genes." Proceedings of the National Academy of Sciences of the United States of America 104, no. 19 (May 2007): 8005-8010.  Full Text  Open Access Copy
    • Bejerano, G, Lowe, CB, Ahituv, N, King, B, Siepel, A, Salama, SR, Rubin, EM, Kent, WJ, and Haussler, D. "A distal enhancer and an ultraconserved exon are derived from a novel retroposon." Nature 441, no. 7089 (May 2006): 87-90.  Full Text
• Teaching & Mentoring
• 

  Recent Courses

  • BIOLOGY 728C: University Program in Genetics and Genomics Biological Solutions Module Ill 2019
  • CMB 778C: University Program in Genetics and Genomics Biological Solutions Module Ill 2019
  • MGM 778C: University Program in Genetics and Genomics Biological Solutions Module Ill 2019
  • UPGEN 701: Advanced Topics in Genetics and Genomics 2019
  • UPGEN 778C: University Program in Genetics and Genomics Biological Solutions Module Ill 2019

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