Craig Lowe | Scholars@Duke

Craig Lowe
Assistant Professor of Molecular Genetics and Microbiology

Current Appointments & Affiliations

Assistant Professor of Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2018
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2019

Contact Information

Background
Education, Training, & Certifications
- Ph.D., University of California at Santa Cruz 2010
Research
Selected Grants
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Pollen, Alex A., Aparna Bhaduri, Madeline G. Andrews, Tomasz J. Nowakowski, Olivia S. Meyerson, Mohammed A. Mostajo-Radji, Elizabeth Di Lullo, et al. “Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution..” Cell 176, no. 4 (February 7, 2019): 743-756.e17. https://doi.org/10.1016/j.cell.2019.01.017.
    Full Text Link to Item
  - Song, Janet H. T., Craig B. Lowe, and David M. Kingsley. “Characterization of a Human-Specific Tandem Repeat Associated with Bipolar Disorder and Schizophrenia..” Am J Hum Genet 103, no. 3 (September 6, 2018): 421–30. https://doi.org/10.1016/j.ajhg.2018.07.011.
    Full Text Link to Item
  - Lowe, Craig B., Nicelio Sanchez-Luege, Timothy R. Howes, Shannon D. Brady, Rhea R. Daugherty, Felicity C. Jones, Michael A. Bell, and David M. Kingsley. “Detecting differential copy number variation between groups of samples..” Genome Res 28, no. 2 (February 2018): 256–65. https://doi.org/10.1101/gr.206938.116.
    Full Text Open Access Copy Link to Item
  - Lowe, Craig B., Julia A. Clarke, Allan J. Baker, David Haussler, and Scott V. Edwards. “Feather development genes and associated regulatory innovation predate the origin of Dinosauria..” Mol Biol Evol 32, no. 1 (January 2015): 23–28. https://doi.org/10.1093/molbev/msu309.
    Full Text Open Access Copy Link to Item
  - Lowe, Craig B., and David Haussler. “29 mammalian genomes reveal novel exaptations of mobile elements for likely regulatory functions in the human genome..” Plos One 7, no. 8 (2012). https://doi.org/10.1371/journal.pone.0043128.
    Full Text Open Access Copy Link to Item
  - Lowe, C. B. “Three periods of regulatory innovation during vertebrate evolution (Science (1019)).” Science 334, no. 6057 (November 11, 2011). https://doi.org/10.1126/science.334.6057.761-b.
    Full Text
  - Lindblad-Toh, Kerstin, Manuel Garber, Or Zuk, Michael F. Lin, Brian J. Parker, Stefan Washietl, Pouya Kheradpour, et al. “A high-resolution map of human evolutionary constraint using 29 mammals..” Nature 478, no. 7370 (October 12, 2011): 476–82. https://doi.org/10.1038/nature10530.
    Full Text Open Access Copy Link to Item
  - Alföldi, Jessica, Federica Di Palma, Manfred Grabherr, Christina Williams, Lesheng Kong, Evan Mauceli, Pamela Russell, et al. “The genome of the green anole lizard and a comparative analysis with birds and mammals..” Nature 477, no. 7366 (August 31, 2011): 587–91. https://doi.org/10.1038/nature10390.
    Full Text Open Access Copy Link to Item
  - Lowe, Craig B., Manolis Kellis, Adam Siepel, Brian J. Raney, Michele Clamp, Sofie R. Salama, David M. Kingsley, Kerstin Lindblad-Toh, and David Haussler. “Three periods of regulatory innovation during vertebrate evolution..” Science 333, no. 6045 (August 19, 2011): 1019–24. https://doi.org/10.1126/science.1202702.
    Full Text Open Access Copy Link to Item
  - Lowe, Craig B., Gill Bejerano, Sofie R. Salama, and David Haussler. “Endangered species hold clues to human evolution..” J Hered 101, no. 4 (July 2010): 437–47. https://doi.org/10.1093/jhered/esq016.
    Full Text Open Access Copy Link to Item
  - McLean, Cory Y., Dave Bristor, Michael Hiller, Shoa L. Clarke, Bruce T. Schaar, Craig B. Lowe, Aaron M. Wenger, and Gill Bejerano. “GREAT improves functional interpretation of cis-regulatory regions..” Nat Biotechnol 28, no. 5 (May 2010): 495–501. https://doi.org/10.1038/nbt.1630.
    Full Text Open Access Copy Link to Item
  - Zhu, Jingchun, J Zachary Sanborn, Mark Diekhans, Craig B. Lowe, Tom H. Pringle, and David Haussler. “Comparative genomics search for losses of long-established genes on the human lineage..” Plos Comput Biol 3, no. 12 (December 2007). https://doi.org/10.1371/journal.pcbi.0030247.
    Full Text Link to Item
  - Wang, Ting, Jue Zeng, Craig B. Lowe, Robert G. Sellers, Sofie R. Salama, Min Yang, Shawn M. Burgess, Rainer K. Brachmann, and David Haussler. “Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53..” Proc Natl Acad Sci U S A 104, no. 47 (November 20, 2007): 18613–18. https://doi.org/10.1073/pnas.0703637104.
    Full Text Open Access Copy Link to Item
  - Lowe, Craig B., Gill Bejerano, and David Haussler. “Thousands of human mobile element fragments undergo strong purifying selection near developmental genes..” Proc Natl Acad Sci U S A 104, no. 19 (May 8, 2007): 8005–10. https://doi.org/10.1073/pnas.0611223104.
    Full Text Open Access Copy Link to Item
  - Bejerano, Gill, Craig B. Lowe, Nadav Ahituv, Bryan King, Adam Siepel, Sofie R. Salama, Edward M. Rubin, W James Kent, and David Haussler. “A distal enhancer and an ultraconserved exon are derived from a novel retroposon..” Nature 441, no. 7089 (May 4, 2006): 87–90. https://doi.org/10.1038/nature04696.
    Full Text Link to Item
Teaching & Mentoring
Recent Courses

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Selected Grants

Selected Publications

Academic Articles

Recent Courses