ConferenceHypertension · September 2025
Dendritic cells (DCs) are implicated in the progression of chronic kidney disease (CKD), and emerging evidence demonstrates that metabolic reprogramming profoundly influences DC differentiation and activation. Dynamin-related p ...
Full textCite
ConferenceHypertension · September 2024
Whereas the ubiquitin editor A20 limits NF-κB-mediated signaling in myeloid leukocytes, the functions of A20 in renal epithelial cells during hypertension have not been described. We recently found that A20 in the kidney tubule ameliorates hyperten ...
Full textCite
ConferenceHypertension · September 2023
Chronic Kidney Disease (CKD) progression may be slowed or stopped with early diagnosis and intervention, so developing novel therapies is paramount. The Wnt acyl transferase porcupine (PORCN) regulates the secretion of all 19 Wnt ligan ...
Full textCite
ConferenceHypertension · September 2021
The ubiquitin-editing protein A20 suppresses NF-κB signaling, which contributes to hypertension and kidney inflammation. However, whether A20 generated directly in the kidney tubule regulates blood pressure requires elucidation. To exa ...
Full textCite
ConferenceFront Immunol · 2021
Intestinal immunity is coordinated by specialized mononuclear phagocyte populations, constituted by a diversity of cell subsets. Although the cell subsets constituting the mononuclear phagocyte network are thought to be similar in both small and large inte ...
Full textLink to itemCite