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Steven Daniel Crowley

Professor of Medicine
Medicine, Nephrology
Duke Box 103015, Durham, NC 27710
2nd Floor, Room 2007, MSRB II, 2 Genome Court, Durham, NC 27710

Scholarly Works - Conferences


Sirtuin-3 Deletion in the Distal Nephron Protects Against Ischemic AKI

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · October 2025 Link to item Cite

Abstract FR489: Drp1 in Myeloid Cells Protects Against Kidney Injury by Suppressing Dendritic Cell Activation and T Cell Accumulation

Conference Hypertension · September 2025 Dendritic cells (DCs) are implicated in the progression of chronic kidney disease (CKD), and emerging evidence demonstrates that metabolic reprogramming profoundly influences DC differentiation and activation. Dynamin-related p ... Full text Cite

Kidney Macrophage IL-1 Receptor Limits Endoplasmic Reticulum Stress and Nephrotoxic Serum Nephritis

Conference Journal of the American Society of Nephrology · October 2024 Full text Cite

Abstract MP33: A20 in the Kidney Epithelium Attenuates Angiotensin II-induced Hypertension by Constraining Renal Tubular NHE3 Expression

Conference Hypertension · September 2024 Whereas the ubiquitin editor A20 limits NF-κB-mediated signaling in myeloid leukocytes, the functions of A20 in renal epithelial cells during hypertension have not been described. We recently found that A20 in the kidney tubule ameliorates hyperten ... Full text Cite

Novel Anti-Inflammatory Effects of IL-1 Receptor in Kidney Myeloid Cells Following AKI

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · November 2023 Link to item Cite

Abstract P183: Porcupine Protects The Kidney By Suppressing Tubular Inflammation And Preserving Mitochondrial Integrity

Conference Hypertension · September 2023 Chronic Kidney Disease (CKD) progression may be slowed or stopped with early diagnosis and intervention, so developing novel therapies is paramount. The Wnt acyl transferase porcupine (PORCN) regulates the secretion of all 19 Wnt ligan ... Full text Cite

Classical Dendritic Cells Mediate Nephrotoxic Serum Nephritis by Activating T Cells

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · October 2021 Link to item Cite

Resident Macrophages Limit IL-6 generation to Protect Against Septic AKI

Conference JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · October 2021 Link to item Cite

Abstract MP31: A20 In Renal Tubular Cells Protects Against Hypertension

Conference Hypertension · September 2021 The ubiquitin-editing protein A20 suppresses NF-κB signaling, which contributes to hypertension and kidney inflammation. However, whether A20 generated directly in the kidney tubule regulates blood pressure requires elucidation. To exa ... Full text Cite

Th17 Immunity in the Colon Is Controlled by Two Novel Subsets of Colon-Specific Mononuclear Phagocytes.

Conference Front Immunol · 2021 Intestinal immunity is coordinated by specialized mononuclear phagocyte populations, constituted by a diversity of cell subsets. Although the cell subsets constituting the mononuclear phagocyte network are thought to be similar in both small and large inte ... Full text Link to item Cite