Scholars@Duke
Cynthia Ann Moylan

Cynthia Ann Moylan

Professor of Medicine
Medicine, Gastroenterology
cynthia.moylan@duke.edu
Duke Box 3256, 595 LaSalle GSRB 1, Durham, NC 27710
Duke South Clinic, 40 Medicine Circle, Room 0350, Durham, NC 27710

Featured Works

Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease.

Journal article Hepatology · February 2014 Featured Work UNLABELLED: Clinicians rely upon the severity of liver fibrosis to segregate patients with well-compensated nonalcoholic fatty liver disease (NAFLD) into subpopulations at high- versus low-risk for eventual liver-related morbidity and mortality. We compare ... Full text Link to item Cite

Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease.

Journal article Gastroenterology · November 2013 Featured Work BACKGROUND & AIMS: Cirrhosis and liver cancer are potential outcomes of advanced nonalcoholic fatty liver disease (NAFLD). It is not clear what factors determine whether patients will develop advanced or mild NAFLD, limiting noninvasive diagnosis and treat ... Full text Link to item Cite

Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis.

Journal article Am J Physiol Gastrointest Liver Physiol · December 2009 Featured Work Myofibroblastic hepatic stellate cells (MF-HSC) are derived from quiescent hepatic stellate cells (Q-HSC). Q-HSC express certain epithelial cell markers and have been reported to form junctional complexes similar to epithelial cells. We have shown that Hed ... Full text Link to item Cite

Disparities in liver transplantation before and after introduction of the MELD score.

Journal article JAMA · November 26, 2008 Featured Work CONTEXT: In February 2002, the allocation system for liver transplantation became based on the Model for End-Stage Liver Disease (MELD) score. Before MELD, black patients were more likely to die or become too sick to undergo liver transplantation compared ... Full text Link to item Cite

Predicting CD4 lymphocyte count <200 cells/mm(3) in an HIV type 1-infected African population.

Journal article AIDS Res Hum Retroviruses · October 2007 Featured Work Clinical criteria are recommended to select HIV-infected patients for initiation of antiretroviral therapy when CD4 lymphocyte testing is unavailable. We evaluated the performance characteristics of WHO staging criteria, anthropometrics, and simple laborat ... Full text Link to item Cite

Treatment of hepatitis C in special populations.

Journal article Clin Liver Dis · November 2005 Featured Work Treatment options for hepatitis C virus (HCV) infection have improved significantly in recent years, however, treatment recommendations came from large clinical trials of highly selected patient populations. HCV infection has increased prevalence in Africa ... Full text Link to item Cite