ConferenceProgress in Biomedical Optics and Imaging Proceedings of SPIE · March 6, 2026
Quantitative 3D imaging can supplement qualitative stereoscopic depth cues in microsurgical settings. Real-time feedback of quantitative 3D information is also important for applications in robotic surgery. Extending previous work on FiLMScope, we introduc ...
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ConferenceRetina · August 2020
PURPOSE: To identify characteristics associated with progression from vitreomacular traction (VMT) to a full-thickness macular hole (FTMH) or lamellar hole (LH). METHODS: Post-hoc analysis of the Phase III clinical trial comparing ocriplasmin with placebo ...
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ConferenceJAMA Ophthalmol · January 1, 2020
IMPORTANCE: Progression of retinopathy of prematurity (ROP) to stage 4 may require surgical intervention. The partial retinal detachment of stage 4 ROP may involve the fovea (stage 4B ROP) or may not (stage 4A ROP). This determination has heretofore been b ...
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ConferenceProgress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2020
Through biomedical engineering partnerships, our group has been able to develop and translate optical coherence tomography (OCT), an imaging tool conventionally used in the "eye imaging suite", for bedside use in unstable infants or for intraoperative guid ...
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ConferenceRetina · October 2019
PURPOSE:: Subretinal delivery of stem cells and gene therapy vectors hold great promise in clinical care. Delivery techniques are evolving. We investigate the utility of 4-dimensional (volumes over time) microscope-integrated optical coherence tomography ( ...
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ConferenceOphthalmology · February 2019
PURPOSE: To evaluate associations of morphologic features with 5-year visual acuity (VA) in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). DESIGN: Cohort study within a randomized clinical trial. PARTICIPANTS: Participants in ...
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ConferenceIEEE International Conference on Intelligent Robots and Systems · December 13, 2017
Intraoperative 3D imaging has great potential for enhancing surgical visualization. This is especially so in ophthalmic surgery where live volumetric imaging from optical coherence tomography systems recently incorporated into surgical microscopes has free ...
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ConferenceOphthalmology · December 2017
PurposeAppearance of geographic atrophy (GA) on color photography (CP) is preceded by specific features on spectral-domain optical coherence tomography (SD OCT). We aimed to build SD OCT-based risk assessment models for 5-year new onset of GA and ...
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ConferenceProgress in Biomedical Optics and Imaging Proceedings of SPIE · January 1, 2016
Ophthalmic surgeons manipulate micron-scale tissues using stereopsis through an operating microscope and instrument shadowing for depth perception. While ophthalmic microsurgery has benefitted from rapid advances in instrumentation and techniques, the basi ...
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ConferenceInvestigative Ophthalmology and Visual Science · December 1, 1997
Purpose. Matrix metalloprotetnases (MMP) and their inhibitors are involved in extracelular matrix turnover and have been proposed to be involved in the pathogenesis of retinal disease such as age-related macular degeneration (AMD). Little is known about th ...
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ConferenceInvestigative Ophthalmology and Visual Science · February 15, 1996
Purpose: Postoperative fibrin formation is common after vitreous surgery for the complications of proliferative diabetic retinopathy and proliferative vitreoretinopathy. We tested the efficacy of a directly acting antithrombin agent, recombinant desulphato ...
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ConferenceInvestigative Ophthalmology and Visual Science · February 15, 1996
Purpose: We wish to identify the pathologic effects of visible ultrashort laser pulses directed to the retina to assist in developing safety standards for such lasers. Methods: Picosecond and femtosecond laser energy was delivered to the retina of the Dutc ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · August 17, 1994
Threshold measurements for Minimum Visible Lesions (MVL) at the retina are reported for femtosecond (fs) and picosecond (ps) laser pulses in Rhesus monkey' eyes using visible wavelengths. The 50% probability for damage (ED50) dosages are calculated for 1 h ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · August 17, 1994
Threshold measurements at 90 femtoseconds (fs) and 600 fs have been made for minimum visible lesions (MVLs) using Dutch Belted rabbit and Rhesus monkey eyes.' Laser induced breakdown (LIB) thresholds on biological materials including vitreous, normal salin ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · August 17, 1994
We present our clinical evaluation of hemorrhagic and non-hemorrhagic 90 fs single pulses in rabbits and ri1 The rabbit and primate eye present unique in vivo models for evaluation Of retinal and choroidal laser induced hemorrhages with distinct difference ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · June 23, 1994
A model laser surgical probe was designed and built to employ laser induced breakdown (LIB) in cutting fibrovascular membranes within the vitreous cavity of the eye. Current surgical techniques for removing such membranes from eyes with severe proliferativ ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · January 1, 1993
The ability of laser-induced plasmas to shield biological tissue from intense exposure to laser pulse energy has been in question for years. Current ocular surgical techniques rely on cone angles of incident pulses to protect delicate tissue anterior and p ...
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