Overview
Treatment of neurodegenerative disorders and cancer that are linked to the apoliporotein E genotype
Current Duke Appointments & Affiliations
Adjunct Associate Professor in the Department of Medicine
·
2009 - Present
Medicine, Hematology,
Medicine
Recent Scholarly Works
Safety and Efficacy of Inhaled Natural Product Powders That Enhance Mucociliary Clearance.
Journal article AAPS PharmSciTech · May 15, 2026 Mucociliary clearance is the lung's primary defense against inhaled pathogens and particulates, requiring optimal airway surface liquid hydration, mucus rheology, and coordinated ciliary beating. Diseases and pollutants disrupt these processes through alte ... Full text Open Access Link to item CiteGeneration of a shelf-stable, broadly-reactive influenza vaccine formulated with TLR4, TLR7/8, or TLR9 stimulating adjuvants.
Journal article Vaccine · February 6, 2026 Vaccine distribution to undeveloped regions of the world is often hindered by the lack of efficient cold-chain networks. In this study, the thin-film freezing (TFF) process was used to freeze-dry next generation influenza vaccines for shelf-stable storage. ... Full text Link to item CitePulmonary and neurobehavioral efficacies of AVR-48, a TLR4 modulator, in a preterm lamb model of bronchopulmonary dysplasia.
Journal article Respir Res · August 25, 2025 BACKGROUND: AVR-48 is a small molecule that modulates toll-like receptor 4 (TLR4) activity, changing macrophage phenotype from pro- to anti-inflammatory and increasing the anti-inflammatory cytokine IL-10. Treatment with AVR-48 via intraperitoneal injectio ... Full text Link to item CiteEducation
University of Utah ·
1993
Ph.D.
Utah State University ·
1987
B.S.