Daniel Raphael Saban

Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology

Ophthalmology, Corneal Diseases

daniel.saban@duke.edu

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At a Glance

Credentials
1. Education

Academic Experience

Global Scholarship

Keywords

Research
1. Selected Grants
2. External Relationships

Scholarly Works

Teaching & Mentoring
1. Recent Courses

Recognition
1. News Items

Professional Activities
1. Leadership & Clinical Positions

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Scholarly Works - Conferences

Inner Plexiform Layer-Specific Microglia Protect the Retinal Pigment Epitheilium in Retinal Degeneration

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · July 1, 2019 Link to item Cite

Elucidatiing niche-associated function of retinal microglia at the single cell level

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · July 1, 2019 Link to item Cite

Tear leukocyte phenotyping in meibomian gland dysfunction by large parameter flow cytometry

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · July 1, 2018 Link to item Cite

Role of Antigen-presenting Cells within Conjunctiva-associated Lymphoid Tissue in the Induction of Ocular Allergy

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · July 1, 2018 Link to item Cite

Recipient-Derived BAFF and Alloantigen Synergistically Activate B Cells in Murine Chronic Gvhd

Conference Blood · December 2, 2016 Featured Publication AbstractIncreased B cell-activating factor (BAFF) and aberrant B cell survival and activation are associated with chronic graft versus host disease (cGVHD) in patients. Whether excessive BAFF production has ... Full text Cite

Pathogenesis of meibomian gland dysfunction (MGD) requires the T cell-neutrophil axis, in the allergy setting

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · September 1, 2016 Link to item Cite

Allergic eye disease (AED) progression in the mouse model is associated with quantitative changes in conjunctival innate lymphoid populations.

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · September 1, 2016 Link to item Cite

Microglia and monocyte-derived macrophage responses to light damage differ across mouse strains

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · September 1, 2016 Link to item Cite

IL-9 upregulation in experimetal allergic conjunctivitis: IL-9R blockade downregulates mast cell responses

Conference ALLERGY · August 1, 2016 Link to item Cite

Dendritic cell derived thrombospondin-1 modulation of primary versus secondary T cell responses in a mouse model of ocular allergy

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

Corneal Lymphangiogenesis Contributes to Egress of Corneal Dendritic Cells in a Mouse Model of Ocular Allergy

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

Single Source Fluorescence Imaging/Blue Optical Coherence Tomography in a GFP Mouse Model

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

CCR7 is critical in the induction and maintenance of Th17 immunity in dry eye disease

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

Resolving wounds induce a more robust cytokine mRNA response and recruitment of larger numbers of neutrophils

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

A novel contribution for dendritic cells in fibrosis pathobiology as revealed in a mouse model of severe ocular allergy

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

Novel Mouse Model of Severe Ocular Allergy Reveals a Key Role for Pathogenic Th17 Cells

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

Intravital multiphoton visualization identifies inter-networking between nerves and bone marrow derived cells of the mouse cornea

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

In Type 1 Diabetes Decreased Bone Marrow Neuronal Support Shifts Normal Hematopoiesis Towards the Generation of (C-C Motif) Receptor 2 Monocytes

Conference CIRCULATION · November 20, 2012 Link to item Cite

Identification and Function of Novel Langerin Positive Dendritic Cells in the Cornea

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2010 Link to item Cite

Regulatory Effects of Early NK Cell Responses on Adaptive Immunity in Dry Eye Disease

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2010 Link to item Cite

Corticosteroids Inhibit Inflammatory Corneal Lymphangigenesis in vivo, but Display Proangiogenic Properties in vitro

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2010 Link to item Cite

Th17/IL17 Mediates Autoimmunity-Dependent Corneal Lymphangiogenesis in Dry Eye Disease

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2010 Link to item Cite

Phenotypic and Functional Characterization of Corneal Langerhans Cells in Transplantation.

Conference AMERICAN JOURNAL OF TRANSPLANTATION · January 1, 2009 Link to item Cite

Chimeric Solid Tissue Grafts Diminish Allospecific Immunity

Conference FASEB JOURNAL · April 1, 2008 Link to item Cite

Immunization of cellular antigens into the anterior chamber impairs cytotoxicity

Conference JOURNAL OF IMMUNOLOGY · April 1, 2006 Link to item Cite

Preferential production of distinct IgG subclasses in response to anterior chamber immunization with allosplenocytes

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · January 1, 2005 Link to item Cite

Optimization of lentiviral gene delivery to the retinal pigment epithelium in vivo

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · May 1, 2003 Link to item Cite

Lentiviral delivery of DH-sCNTF to RPE in P23H rats rescues photoreceptor cells morphologically but not functionally

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · May 1, 2002 Link to item Cite

Prolongation of recombinant adenoviral expression through modulation of the innate ocular immunity

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · May 1, 2002 Link to item Cite

Viral vectors for efficient gene delivery to RPE cells.

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · March 15, 2001 Link to item Cite